Latest content added for UNT Digital Library Searchhttps://digital2.library.unt.edu/search/?t=fulltext&fq=str_year%3A2000&sort=added_a2021-12-17T20:14:08-06:00UNT LibrariesThis is a custom feed for searching UNT Digital Library SearchPhosphorylation of Myosin Light Chain Kinase by p21-activated Kinase PAK22021-12-17T20:14:08-06:00https://digital.library.unt.edu/ark:/67531/metadc1871053/<p><a href="https://digital.library.unt.edu/ark:/67531/metadc1871053/"><img alt="Phosphorylation of Myosin Light Chain Kinase by p21-activated Kinase PAK2" title="Phosphorylation of Myosin Light Chain Kinase by p21-activated Kinase PAK2" src="https://digital.library.unt.edu/ark:/67531/metadc1871053/thumbnail/"/></a></p><p>Article reporting that PAK2, a member of the Rho family of GTPase-dependent kinases, regulates isometric tension development and myosin II RLC phosphorylation in saponin permeabilized endothelial monolayers. The results demonstrate that PAK2 can directly phosphorylate MLCK, inhibiting its activity and limiting the development of isometric tension.</p>