Latest content added for UNT Digital Library Searchhttps://digital2.library.unt.edu/search/?t=fulltext&fq=str_degree_department%3ABiological+Sciences&sort=added_d2024-03-05T14:22:19-06:00UNT LibrariesThis is a custom feed for searching UNT Digital Library SearchA gene network-driven approach to infer novel pathogenicity-associated genes: application to Pseudomonas aeruginosa PAO12024-03-05T14:22:19-06:00https://digital.library.unt.edu/ark:/67531/metadc2288911/<p><a href="https://digital.library.unt.edu/ark:/67531/metadc2288911/"><img alt="A gene network-driven approach to infer novel pathogenicity-associated genes: application to Pseudomonas aeruginosa PAO1" title="A gene network-driven approach to infer novel pathogenicity-associated genes: application to Pseudomonas aeruginosa PAO1" src="https://digital.library.unt.edu/ark:/67531/metadc2288911/thumbnail/"/></a></p><p>Article describes how within the genome of a pathogen is the information regarding factors responsible for its pathogenicity. the authors of the article developed a novel pipeline that uses standard protocol in combination with gene co-expression network of a pathogen constructed using publicly available RNA-Seq data sets.</p>Using Machine Learning to Predict Genes Underlying Differentiation of Multipartite and Unipartite Traits in Bacteria2024-03-05T14:22:08-06:00https://digital.library.unt.edu/ark:/67531/metadc2288910/<p><a href="https://digital.library.unt.edu/ark:/67531/metadc2288910/"><img alt="Using Machine Learning to Predict Genes Underlying Differentiation of Multipartite and Unipartite Traits in Bacteria" title="Using Machine Learning to Predict Genes Underlying Differentiation of Multipartite and Unipartite Traits in Bacteria" src="https://digital.library.unt.edu/ark:/67531/metadc2288910/thumbnail/"/></a></p><p>Article describes how, since the discovery of the second chromosome in the Rhodobacter spaeroides 2.4.1 in 1989 and the revelation of gene sequences, multipartite genomes have been reported in over three hundred bacterial species under nine different phyla. In this study, the authors have attempted to leverage machine learning as a means to identify the genetic factors that underlie the differentiation of bacteria with multipartite and unipartite genomes.</p>Silicon versus Superbug: Assessing Machine Learning's Role in the Fight against Antimicrobial Resistance2024-03-05T14:20:14-06:00https://digital.library.unt.edu/ark:/67531/metadc2288893/<p><a href="https://digital.library.unt.edu/ark:/67531/metadc2288893/"><img alt="Silicon versus Superbug: Assessing Machine Learning's Role in the Fight against Antimicrobial Resistance" title="Silicon versus Superbug: Assessing Machine Learning's Role in the Fight against Antimicrobial Resistance" src="https://digital.library.unt.edu/ark:/67531/metadc2288893/thumbnail/"/></a></p><p>Article describes how, in his 1945 Nobel Prize acceptance speech, Sir Alexander Fleming warned of antimicrobial resistance (AMR) if the necessary precautions were not taken diligently. This paper explores the applications of ML in predicting and understanding AMR, highlighting its potential in revolutionizing healthcare practices.</p>Lipid Droplets: Packing Hydrophobic Molecules Within the Aqueous Cytoplasm2023-12-14T05:17:52-06:00https://digital.library.unt.edu/ark:/67531/metadc2201660/<p><a href="https://digital.library.unt.edu/ark:/67531/metadc2201660/"><img alt="Lipid Droplets: Packing Hydrophobic Molecules Within the Aqueous Cytoplasm" title="Lipid Droplets: Packing Hydrophobic Molecules Within the Aqueous Cytoplasm" src="https://digital.library.unt.edu/ark:/67531/metadc2201660/thumbnail/"/></a></p><p>Article discusses how lipid droplets, also known as oil bodies or lipid bodies, are plant organelles that compartmentalize neutral lipids as a hydrophobic matrix covered by proteins embedded in a phospholipid monolayer. The authors review the growing body of knowledge about lipid droplets in plant cells, describe the evolutionary similarity and divergence in their associated subcellular machinery, and point to gaps that deserve future attention.</p>The protein conformational basis of isoflavone biosynthesis2023-10-12T14:19:29-05:00https://digital.library.unt.edu/ark:/67531/metadc2179468/<p><a href="https://digital.library.unt.edu/ark:/67531/metadc2179468/"><img alt="The protein conformational basis of isoflavone biosynthesis" title="The protein conformational basis of isoflavone biosynthesis" src="https://digital.library.unt.edu/ark:/67531/metadc2179468/thumbnail/"/></a></p><p>Authors of the article assert that isoflavonoids play important roles in plant defense and also exhibit a range of mammalian health-promoting activities. They emphasize that understanding the structural basis of isoflavone biosynthesis will facilitate the engineering of new bioactive isoflavonoids.</p>Prebiotic/probiotic supplementation resulted in reduced visceral fat and mRNA expression associated with adipose tissue inflammation, systemic inflammation, and chronic disease risk2023-10-12T14:17:40-05:00https://digital.library.unt.edu/ark:/67531/metadc2179450/<p><a href="https://digital.library.unt.edu/ark:/67531/metadc2179450/"><img alt="Prebiotic/probiotic supplementation resulted in reduced visceral fat and mRNA expression associated with adipose tissue inflammation, systemic inflammation, and chronic disease risk" title="Prebiotic/probiotic supplementation resulted in reduced visceral fat and mRNA expression associated with adipose tissue inflammation, systemic inflammation, and chronic disease risk" src="https://digital.library.unt.edu/ark:/67531/metadc2179450/thumbnail/"/></a></p><p>Article describes how prebiotic/probiotic supplementation represents a viable option for addressing elevated systemic inflammation and chronic disease risk in overweight individuals. The key findings support that 90-day prebiotic/probiotic supplementation may be associated with reduced adipose tissue inflammation, reduced systemic inflammation, and reduced chronic disease risk.</p>The complexities of proanthocyanidin biosynthesis and its regulation in plants2023-10-12T14:14:57-05:00https://digital.library.unt.edu/ark:/67531/metadc2179412/<p><a href="https://digital.library.unt.edu/ark:/67531/metadc2179412/"><img alt="The complexities of proanthocyanidin biosynthesis and its regulation in plants" title="The complexities of proanthocyanidin biosynthesis and its regulation in plants" src="https://digital.library.unt.edu/ark:/67531/metadc2179412/thumbnail/"/></a></p><p>Article describes how proanthocyanidins (PAs) are natural flavan-3-ol polymers that contribute protection to plants under biotic and abiotic stress, benefits to human health, and bitterness and astringency to food products. This review extends the conventional understanding with recent findings that provide new insights to address lingering questions and focus strategies for manipulating PA traits in plants.</p>Transcriptomic profiling of miR-203a inhibitor and miR-34b-injected zebrafish (Danio rerio) validates oil-induced neurological, cardiovascular and eye toxicity response pathways2023-10-12T14:14:23-05:00https://digital.library.unt.edu/ark:/67531/metadc2179396/<p><a href="https://digital.library.unt.edu/ark:/67531/metadc2179396/"><img alt="Transcriptomic profiling of miR-203a inhibitor and miR-34b-injected zebrafish (Danio rerio) validates oil-induced neurological, cardiovascular and eye toxicity response pathways" title="Transcriptomic profiling of miR-203a inhibitor and miR-34b-injected zebrafish (Danio rerio) validates oil-induced neurological, cardiovascular and eye toxicity response pathways" src="https://digital.library.unt.edu/ark:/67531/metadc2179396/thumbnail/"/></a></p><p>Article discusses how the global sequencing of microRNA (miRNA; miR) and integration to downstream mRNA expression profiles in early life stages (ELS) of fish following exposure to crude oil determined consistently dysregulated miRNAs regardless of the oil source or fish species. The overlay of differentially expressed miRNAs and mRNAs into in silico software determined that the key roles of these miRNAs were predicted to be involved in cardiovascular, neurological and visually-mediated pathways.</p>Reconstructing horizontal gene flow network to understand prokaryotic evolution2023-09-21T06:33:21-05:00https://digital.library.unt.edu/ark:/67531/metadc2178774/<p><a href="https://digital.library.unt.edu/ark:/67531/metadc2178774/"><img alt="Reconstructing horizontal gene flow network to understand prokaryotic evolution" title="Reconstructing horizontal gene flow network to understand prokaryotic evolution" src="https://digital.library.unt.edu/ark:/67531/metadc2178774/thumbnail/"/></a></p><p>Article says that horizontal gene transfer (HGT) is a major source of phenotypic innovation and a mechanism of niche adaptation in prokaryotes. Methods for detecting HGT can be classified into phylogenetic-based and parametric or composition-based approaches, so authors exploited the complementary strengths of both the approaches to construct a high confidence horizontal gene flow network. The scale-free horizontal gene flow network presented here provides new insights into modes of transfer for the exchange of genetic information and also illuminates differential gene flow across phyla.</p>A lipidomics platform to analyze the fatty acid compositions of non-polar and polar lipid molecular species from plant tissues: Examples from developing seeds and seedlings of pennycress (Thlaspi arvense)2023-09-21T06:31:36-05:00https://digital.library.unt.edu/ark:/67531/metadc2178736/<p><a href="https://digital.library.unt.edu/ark:/67531/metadc2178736/"><img alt="A lipidomics platform to analyze the fatty acid compositions of non-polar and polar lipid molecular species from plant tissues: Examples from developing seeds and seedlings of pennycress (Thlaspi arvense)" title="A lipidomics platform to analyze the fatty acid compositions of non-polar and polar lipid molecular species from plant tissues: Examples from developing seeds and seedlings of pennycress (Thlaspi arvense)" src="https://digital.library.unt.edu/ark:/67531/metadc2178736/thumbnail/"/></a></p><p>Article describes a stepwise targeted lipidomics approach to characterize the polar and non-polar lipid classes using complementary LC-MS methods. This lipidomics workflow was applied to developing, mature, and germinated pennycress seeds/seedlings and found unexpected changes among several lipid molecular species.</p>Manipulating plasma thyroid hormone levels alters development of endothermy and ventilation in nestling red-winged blackbirds2023-09-21T06:31:32-05:00https://digital.library.unt.edu/ark:/67531/metadc2178735/<p><a href="https://digital.library.unt.edu/ark:/67531/metadc2178735/"><img alt="Manipulating plasma thyroid hormone levels alters development of endothermy and ventilation in nestling red-winged blackbirds" title="Manipulating plasma thyroid hormone levels alters development of endothermy and ventilation in nestling red-winged blackbirds" src="https://digital.library.unt.edu/ark:/67531/metadc2178735/thumbnail/"/></a></p><p>Authors of the article propose that thyroid hormones play an important role in regulating development of endothermy during the nestling period in altricial birds. Their data suggests plasma thyroid hormone levels play an active role in the systemic development of endothermic capacity and the development of ventilatory control.</p>Embryonic developmental oxygen preconditions cardiovascular functional response to acute hypoxic exposure and maximal β-adrenergic stimulation of anesthetized juvenile American alligators (Alligator mississippiensis)2022-06-15T15:19:16-05:00https://digital.library.unt.edu/ark:/67531/metadc1944185/<p><a href="https://digital.library.unt.edu/ark:/67531/metadc1944185/"><img alt="Embryonic developmental oxygen preconditions cardiovascular functional response to acute hypoxic exposure and maximal β-adrenergic stimulation of anesthetized juvenile American alligators (Alligator mississippiensis)" title="Embryonic developmental oxygen preconditions cardiovascular functional response to acute hypoxic exposure and maximal β-adrenergic stimulation of anesthetized juvenile American alligators (Alligator mississippiensis)" src="https://digital.library.unt.edu/ark:/67531/metadc1944185/thumbnail/"/></a></p><p>Article investigating the effect of embryonic hypoxia on the cardiovascular phenotype of 4-year-old American alligators (Alligator mississippiensis). The findings indicate that embryonic hypoxia in crocodilians alters the cardiovascular phenotype, changing the juvenile response to acute hypoxia and β-adrenergic stimulation.</p>The future of legume genetic data resources: Challenges, opportunities, and priorities2022-06-15T15:17:54-05:00https://digital.library.unt.edu/ark:/67531/metadc1944153/<p><a href="https://digital.library.unt.edu/ark:/67531/metadc1944153/"><img alt="The future of legume genetic data resources: Challenges, opportunities, and priorities" title="The future of legume genetic data resources: Challenges, opportunities, and priorities" src="https://digital.library.unt.edu/ark:/67531/metadc1944153/thumbnail/"/></a></p><p>This article is a commentary on the future of legume genetic data resources and summarizes the workshop held in March of 2019 by the Legume Genomic Data Working Group that addressed questions of data resources and priorities for legumes.</p>RNaseH-mediated simultaneous piggyback knockdown of multiple genes in adult zebrafish2022-05-27T06:00:57-05:00https://digital.library.unt.edu/ark:/67531/metadc1934203/<p><a href="https://digital.library.unt.edu/ark:/67531/metadc1934203/"><img alt="RNaseH-mediated simultaneous piggyback knockdown of multiple genes in adult zebrafish" title="RNaseH-mediated simultaneous piggyback knockdown of multiple genes in adult zebrafish" src="https://digital.library.unt.edu/ark:/67531/metadc1934203/thumbnail/"/></a></p><p>This article tests if it is possible to piggyback more than one antisense deoxyoligonucleotide (dO) with one vivo morpholino (VMO). The authors previously developed a piggyback knockdown method that was used to knockdown genes in adult zebrafish. In this article, the authors develop a method to knockdown three genes at one time, and by increasing the concentration of VMO by twofold, could knockdown six genes simultaneously. These multiple gene knockdowns will not only increase the efficiency of the method in whole genome-wide knockdowns but will also be useful to study multifactorial disorders.</p>Editorial: Biofuels and Bioenergy2022-05-27T05:55:27-05:00https://digital.library.unt.edu/ark:/67531/metadc1934136/<p><a href="https://digital.library.unt.edu/ark:/67531/metadc1934136/"><img alt="Editorial: Biofuels and Bioenergy" title="Editorial: Biofuels and Bioenergy" src="https://digital.library.unt.edu/ark:/67531/metadc1934136/thumbnail/"/></a></p><p>Editorial on the research topic of biofuels and bioenergy.</p>Were domestic camelids present on the prehispanic South American agricultural frontier? An ancient DNA study2022-05-27T05:52:16-05:00https://digital.library.unt.edu/ark:/67531/metadc1934092/<p><a href="https://digital.library.unt.edu/ark:/67531/metadc1934092/"><img alt="Were domestic camelids present on the prehispanic South American agricultural frontier? An ancient DNA study" title="Were domestic camelids present on the prehispanic South American agricultural frontier? An ancient DNA study" src="https://digital.library.unt.edu/ark:/67531/metadc1934092/thumbnail/"/></a></p><p>Article testing the hypothesis that domesticated camelids occurred in prehispanic, southern Mendoza through analysis of ancient DNA.</p>CaMV35S promoter – A plant biology and biotechnology workhorse in the era of synthetic biology2022-05-27T05:46:47-05:00https://digital.library.unt.edu/ark:/67531/metadc1934009/<p><a href="https://digital.library.unt.edu/ark:/67531/metadc1934009/"><img alt="CaMV35S promoter – A plant biology and biotechnology workhorse in the era of synthetic biology" title="CaMV35S promoter – A plant biology and biotechnology workhorse in the era of synthetic biology" src="https://digital.library.unt.edu/ark:/67531/metadc1934009/thumbnail/"/></a></p><p>This review article calls for establishing the CaMV 35S promoter as a quantitative reference standard for transcription activity in plants.</p>Role of ribosomal RNA released from red cells in blood coagulation in zebrafish and humans2022-01-14T16:33:04-06:00https://digital.library.unt.edu/ark:/67531/metadc1877585/<p><a href="https://digital.library.unt.edu/ark:/67531/metadc1877585/"><img alt="Role of ribosomal RNA released from red cells in blood coagulation in zebrafish and humans" title="Role of ribosomal RNA released from red cells in blood coagulation in zebrafish and humans" src="https://digital.library.unt.edu/ark:/67531/metadc1877585/thumbnail/"/></a></p><p>This article identifies that an rRNA released in hemolysis activates clotting in human and zebrafish plasma. Furthermore, it shows that fish Hgfac plays a role in rRNA-mediated activation of coagulation.</p>Isorhamnetin Inhibits Proliferation and Invasion and Induces Apoptosis through the Modulation of Peroxisome Proliferator-activated Receptor γ Activation Pathway in Gastric Cancer2021-12-17T20:15:19-06:00https://digital.library.unt.edu/ark:/67531/metadc1871081/<p><a href="https://digital.library.unt.edu/ark:/67531/metadc1871081/"><img alt="Isorhamnetin Inhibits Proliferation and Invasion and Induces Apoptosis through the Modulation of Peroxisome Proliferator-activated Receptor γ Activation Pathway in Gastric Cancer" title="Isorhamnetin Inhibits Proliferation and Invasion and Induces Apoptosis through the Modulation of Peroxisome Proliferator-activated Receptor γ Activation Pathway in Gastric Cancer" src="https://digital.library.unt.edu/ark:/67531/metadc1871081/thumbnail/"/></a></p><p>Article investigating the potential effects of isorhamnetin (IH), a 3′-O-methylated metabolite of quercetin on the peroxisome proliferator-activated receptor γ (PPAR-γ) signaling cascade using proteomics technology platform, GC cell lines, and xenograft mice model. The study y proposes a novel agent for gastric cancer treatment.</p>Zebrafish Genetics: Functional Genomics2021-11-30T07:17:39-06:00https://digital.library.unt.edu/ark:/67531/metadc1858624/<p><a href="https://digital.library.unt.edu/ark:/67531/metadc1858624/"><img alt="Zebrafish Genetics: Functional Genomics" title="Zebrafish Genetics: Functional Genomics" src="https://digital.library.unt.edu/ark:/67531/metadc1858624/thumbnail/"/></a></p><p>Video recording of Dr. Pudur Jagadeeswaran's presentation, "Zebrafish Genetics: Functional Genomics." It focuses on blood coagulation pathways in studying functional genomics. It was presented at the Transdisciplinary Ancestral Genomic Research Investigations (TAGRI) II Conference held online November 5-6, 2021.</p>Effect of increased embryonic temperature during developmental windows on survival, morphology and oxygen consumption of rainbow trout (Oncorhynchus mykiss)2021-10-21T11:25:50-05:00https://digital.library.unt.edu/ark:/67531/metadc1852213/<p><a href="https://digital.library.unt.edu/ark:/67531/metadc1852213/"><img alt="Effect of increased embryonic temperature during developmental windows on survival, morphology and oxygen consumption of rainbow trout (Oncorhynchus mykiss)" title="Effect of increased embryonic temperature during developmental windows on survival, morphology and oxygen consumption of rainbow trout (Oncorhynchus mykiss)" src="https://digital.library.unt.edu/ark:/67531/metadc1852213/thumbnail/"/></a></p><p>This article applies a developmental 3-dimensional critical window experimental design for a vertebrate, using time, temperature, and phenotypic response (i.e., variables measured). To assess thermal effects on fish development, the authors examined trout hatchling phenotypes following rearing in constant temperatures (5, 10, 15 and 17.5 °C) and following exposure to increased temperature above 5 °C during specific developmental windows.</p>In situ cardiac performance of Atlantic cod (Gadus morhua) at cold temperatures: long-term acclimation, acute thermal challenge and the role of adrenaline2021-09-22T14:32:41-05:00https://digital.library.unt.edu/ark:/67531/metadc1838882/<p><a href="https://digital.library.unt.edu/ark:/67531/metadc1838882/"><img alt="In situ cardiac performance of Atlantic cod (Gadus morhua) at cold temperatures: long-term acclimation, acute thermal challenge and the role of adrenaline" title="In situ cardiac performance of Atlantic cod (Gadus morhua) at cold temperatures: long-term acclimation, acute thermal challenge and the role of adrenaline" src="https://digital.library.unt.edu/ark:/67531/metadc1838882/thumbnail/"/></a></p><p>This article measures the cardiac performance of Newfoundland Atlantic cod (Gadus morhua). The results: (1) show that maximum performance of the isolated cod heart is not compromised by exposure to cold temperatures; and (2) support data from other studies, which show that, in contrast to salmonids, cod cardiac performance/myocardial contractility is not dependent upon humoral adrenergic stimulation.</p>How Tiny Zebrafish and Their Surprisingly Human-Like Genome Can Benefit Medical Research2021-03-05T13:00:06-06:00https://digital.library.unt.edu/ark:/67531/metadc1757974/<p><a href="https://digital.library.unt.edu/ark:/67531/metadc1757974/"><img alt="How Tiny Zebrafish and Their Surprisingly Human-Like Genome Can Benefit Medical Research" title="How Tiny Zebrafish and Their Surprisingly Human-Like Genome Can Benefit Medical Research" src="https://digital.library.unt.edu/ark:/67531/metadc1757974/thumbnail/"/></a></p><p>Presentation highlighting the use of zebrafish to identify genes relating to predisposition to thromboembolism and cardiovascular disease in people with African ancestry. It was presented at the UNT Transdisciplinary Conference on Ancestral Genomics Research which was held virtually on November 20-21, 2020.</p>Targeting Peroxisome Proliferator-Activated Receptor-Gamma (PPARγ) Signaling Cascade for the Prevention and Treatment of Prostate Cancer2020-08-03T15:07:04-05:00https://digital.library.unt.edu/ark:/67531/metadc1705490/<p><a href="https://digital.library.unt.edu/ark:/67531/metadc1705490/"><img alt="Targeting Peroxisome Proliferator-Activated Receptor-Gamma (PPARγ) Signaling Cascade for the Prevention and Treatment of Prostate Cancer" title="Targeting Peroxisome Proliferator-Activated Receptor-Gamma (PPARγ) Signaling Cascade for the Prevention and Treatment of Prostate Cancer" src="https://digital.library.unt.edu/ark:/67531/metadc1705490/thumbnail/"/></a></p><p>Article reviews PPARγ as an antitumor agent and summarizes the antineoplastic effects of PPARγ agonists in prostate cancer.</p>Muconic acid production from methane using rationally-engineered methanotrophic biocatalysts2020-08-03T15:07:04-05:00https://digital.library.unt.edu/ark:/67531/metadc1705486/<p><a href="https://digital.library.unt.edu/ark:/67531/metadc1705486/"><img alt="Muconic acid production from methane using rationally-engineered methanotrophic biocatalysts" title="Muconic acid production from methane using rationally-engineered methanotrophic biocatalysts" src="https://digital.library.unt.edu/ark:/67531/metadc1705486/thumbnail/"/></a></p><p>Article demonstrates bioconversion of methane to muconic acid, a dicarboxylic acid that can be upgraded to an array of platform chemicals, by three gammaproteobacterial methanotrophs.</p>Rapid Responses to Abiotic Stress: Priming the Landscape for the Signal Transduction Network2019-06-13T07:27:03-05:00https://digital.library.unt.edu/ark:/67531/metadc1506245/<p><a href="https://digital.library.unt.edu/ark:/67531/metadc1506245/"><img alt="Rapid Responses to Abiotic Stress: Priming the Landscape for the Signal Transduction Network" title="Rapid Responses to Abiotic Stress: Priming the Landscape for the Signal Transduction Network" src="https://digital.library.unt.edu/ark:/67531/metadc1506245/thumbnail/"/></a></p><p>This article proposes that the integration of these signals is mediated through pulses of gene expression that are coordinated through out the plant in a systemic manner by the ROS/Ca⁺² waves.</p>Immunized Plants: An Answer to Global Hunger2019-03-15T11:51:16-05:00https://digital.library.unt.edu/ark:/67531/metadc1459161/<p><a href="https://digital.library.unt.edu/ark:/67531/metadc1459161/"><img alt="Immunized Plants: An Answer to Global Hunger" title="Immunized Plants: An Answer to Global Hunger" src="https://digital.library.unt.edu/ark:/67531/metadc1459161/thumbnail/"/></a></p><p>Video from the Fall 2018 3 Minute Thesis (3MT®) Final Competition. In this video, Devasantosh Mohanty presents his research methods, findings, and its significance in non-technical language.</p>Diabetes Treatment with Sunshine2019-03-15T11:51:16-05:00https://digital.library.unt.edu/ark:/67531/metadc1459164/<p><a href="https://digital.library.unt.edu/ark:/67531/metadc1459164/"><img alt="Diabetes Treatment with Sunshine" title="Diabetes Treatment with Sunshine" src="https://digital.library.unt.edu/ark:/67531/metadc1459164/thumbnail/"/></a></p><p>Video from the Fall 2018 3 Minute Thesis (3MT®) Final Competition. In this video, Sujata Argawal presents her research methods, findings, and its significance in non-technical language.</p>Xenopus and the art of oxygen maintenance2019-01-12T17:20:31-06:00https://digital.library.unt.edu/ark:/67531/metadc1404223/<p><a href="https://digital.library.unt.edu/ark:/67531/metadc1404223/"><img alt="Xenopus and the art of oxygen maintenance" title="Xenopus and the art of oxygen maintenance" src="https://digital.library.unt.edu/ark:/67531/metadc1404223/thumbnail/"/></a></p><p>This column article discusses the impact of Robert Boutillier and Graham Shelton's 1986 Journal of Experimental Biology paper "Gas exchange, storage and transport in voluntarily diving Xenopus laevis."</p>Deciphering pathogenicity and antibiotic resistance islands in methicillin-resistant Staphylococcus aureus genomes2018-07-30T12:01:24-05:00https://digital.library.unt.edu/ark:/67531/metadc1213690/<p><a href="https://digital.library.unt.edu/ark:/67531/metadc1213690/"><img alt="Deciphering pathogenicity and antibiotic resistance islands in methicillin-resistant Staphylococcus aureus genomes" title="Deciphering pathogenicity and antibiotic resistance islands in methicillin-resistant Staphylococcus aureus genomes" src="https://digital.library.unt.edu/ark:/67531/metadc1213690/thumbnail/"/></a></p><p>This article explores the use of an information-entropy-based gene clustering method for genomic island detection in MRSA.</p>Allelic differences in Medicago truncatula NIP/LATD mutants correlate with their encoded proteins’ transport activities in planta2018-03-29T22:10:46-05:00https://digital.library.unt.edu/ark:/67531/metadc1115863/<p><a href="https://digital.library.unt.edu/ark:/67531/metadc1115863/"><img alt="Allelic differences in Medicago truncatula NIP/LATD mutants correlate with their encoded proteins’ transport activities in planta" title="Allelic differences in Medicago truncatula NIP/LATD mutants correlate with their encoded proteins’ transport activities in planta" src="https://digital.library.unt.edu/ark:/67531/metadc1115863/thumbnail/"/></a></p><p>This article examines the hypothesis that MtNIP/LATD may have another biochemical activity.</p>C. Elegans and Mutants With Chronic Nicotine Exposure as a Novel Model of Cancer Phenotype2017-12-14T11:26:10-06:00https://digital.library.unt.edu/ark:/67531/metadc1049751/<p><a href="https://digital.library.unt.edu/ark:/67531/metadc1049751/"><img alt="C. Elegans and Mutants With Chronic Nicotine Exposure as a Novel Model of Cancer Phenotype" title="C. Elegans and Mutants With Chronic Nicotine Exposure as a Novel Model of Cancer Phenotype" src="https://digital.library.unt.edu/ark:/67531/metadc1049751/thumbnail/"/></a></p><p>This article provides evidence in support of C. elegans as initial in vivo model to study nicotine and its effects on oncogenic mutations identified in humans.</p>Dynamic Changes in Transcriptome and Cell Wall Composition Underlying Brassinosteroid‑Mediated Lignification of Switchgrass Suspension Cells2017-12-14T11:26:10-06:00https://digital.library.unt.edu/ark:/67531/metadc1049706/<p><a href="https://digital.library.unt.edu/ark:/67531/metadc1049706/"><img alt="Dynamic Changes in Transcriptome and Cell Wall Composition Underlying Brassinosteroid‑Mediated Lignification of Switchgrass Suspension Cells" title="Dynamic Changes in Transcriptome and Cell Wall Composition Underlying Brassinosteroid‑Mediated Lignification of Switchgrass Suspension Cells" src="https://digital.library.unt.edu/ark:/67531/metadc1049706/thumbnail/"/></a></p><p>This article provides an overview of the dynamic compositional changes during brassinosteroid-induced cell wall remodeling, and identifies candidate genes for future plant genetic engineering to overcome cell wall recalcitrance.</p>River Notes: A Natural and Human History of the COlorado2017-08-29T09:38:41-05:00https://digital.library.unt.edu/ark:/67531/metadc991009/<p><a href="https://digital.library.unt.edu/ark:/67531/metadc991009/"><img alt="River Notes: A Natural and Human History of the COlorado" title="River Notes: A Natural and Human History of the COlorado" src="https://digital.library.unt.edu/ark:/67531/metadc991009/thumbnail/"/></a></p><p>This article reviews the book "River Notes: A Natural and Human History of the Colorado" by Wade Davis.</p>Gray Wolf Exposure to Emerging Vector-Borne Diseases in Wisconsin with Comparison to Domestic Dogs and Humans2017-07-11T19:49:35-05:00https://digital.library.unt.edu/ark:/67531/metadc984087/<p><a href="https://digital.library.unt.edu/ark:/67531/metadc984087/"><img alt="Gray Wolf Exposure to Emerging Vector-Borne Diseases in Wisconsin with Comparison to Domestic Dogs and Humans" title="Gray Wolf Exposure to Emerging Vector-Borne Diseases in Wisconsin with Comparison to Domestic Dogs and Humans" src="https://digital.library.unt.edu/ark:/67531/metadc984087/thumbnail/"/></a></p><p>This article contains the evaluation of temporal and geographic patterns of exposure to these four vector-borne diseases in Wisconsin as the Gray Wolf population expanded between 1985 and 2011.</p>Malonylation of Glucosylated N-Lauroylethanolamine: A New Pathway That Determines N-Acylethanolamine Metabolic Fate in Plants2017-05-11T16:15:11-05:00https://digital.library.unt.edu/ark:/67531/metadc974467/<p><a href="https://digital.library.unt.edu/ark:/67531/metadc974467/"><img alt="Malonylation of Glucosylated N-Lauroylethanolamine: A New Pathway That Determines N-Acylethanolamine Metabolic Fate in Plants" title="Malonylation of Glucosylated N-Lauroylethanolamine: A New Pathway That Determines N-Acylethanolamine Metabolic Fate in Plants" src="https://digital.library.unt.edu/ark:/67531/metadc974467/thumbnail/"/></a></p><p>This article focuses on the gene At5g39050, which encodes a phenolic glucoside malonyltransferase 1 (PMAT1), to better understand the biological significance of N-lauroylethanolamine (NAE 12:0)-induced gene expression changes.</p>We Need Better Understanding About Functional Diversity and Vulnerability of Tropical Freshwater Fishes2017-05-11T16:15:11-05:00https://digital.library.unt.edu/ark:/67531/metadc974480/<p><a href="https://digital.library.unt.edu/ark:/67531/metadc974480/"><img alt="We Need Better Understanding About Functional Diversity and Vulnerability of Tropical Freshwater Fishes" title="We Need Better Understanding About Functional Diversity and Vulnerability of Tropical Freshwater Fishes" src="https://digital.library.unt.edu/ark:/67531/metadc974480/thumbnail/"/></a></p><p>This commentary extends a discussion initiated by Toussaint et al. (Sci Rep 6:22125, 2016) concerning the relationship between global patterns of freshwater fish functional diversity (FD) and its vulnerability to human impacts.</p>A determination of the spatial concordance between Lyme disease incidence and habitat probability of its primary vector Ixodes scapularis (black-legged tick)2016-10-06T22:24:21-05:00https://digital.library.unt.edu/ark:/67531/metadc910338/<p><a href="https://digital.library.unt.edu/ark:/67531/metadc910338/"><img alt="A determination of the spatial concordance between Lyme disease incidence and habitat probability of its primary vector Ixodes scapularis (black-legged tick)" title="A determination of the spatial concordance between Lyme disease incidence and habitat probability of its primary vector Ixodes scapularis (black-legged tick)" src="https://digital.library.unt.edu/ark:/67531/metadc910338/thumbnail/"/></a></p><p>This article involves mapping the probability of occurrence that the disease vector exists in the environment, mapping the incidence of Lyme disease in the human population and examining the spatial concordance between the probability map and incidence map.</p>Modelling spatial concordance between Rocky Mountain spotted fever disease incidence and habitat probability of its vector Dermacentor variabilis (American dog tick)2016-10-06T22:24:21-05:00https://digital.library.unt.edu/ark:/67531/metadc910329/<p><a href="https://digital.library.unt.edu/ark:/67531/metadc910329/"><img alt="Modelling spatial concordance between Rocky Mountain spotted fever disease incidence and habitat probability of its vector Dermacentor variabilis (American dog tick)" title="Modelling spatial concordance between Rocky Mountain spotted fever disease incidence and habitat probability of its vector Dermacentor variabilis (American dog tick)" src="https://digital.library.unt.edu/ark:/67531/metadc910329/thumbnail/"/></a></p><p>This article reports on the development and comparison of two maps of Texas related to Rocky Mountain spotted fever.</p>Activation of apoptosis in NAF-1-deficient human epithelial breast cancer cells2016-08-31T10:05:56-05:00https://digital.library.unt.edu/ark:/67531/metadc862674/<p><a href="https://digital.library.unt.edu/ark:/67531/metadc862674/"><img alt="Activation of apoptosis in NAF-1-deficient human epithelial breast cancer cells" title="Activation of apoptosis in NAF-1-deficient human epithelial breast cancer cells" src="https://digital.library.unt.edu/ark:/67531/metadc862674/thumbnail/"/></a></p><p>This article shows that small hairpin RNA-mediated suppresion of NAF-1 results in the activation of apoptosis in epithelial breast cancer cells and xenograft tumors.</p>Crystal structure of (3E,5E)-3,5-bis[4-(diethylazaniumyl)benzylidene]-1-methyl-4-oxopiperidin-1-ium trichloride dihydrate: a potential biophotonic material2016-08-31T10:05:56-05:00https://digital.library.unt.edu/ark:/67531/metadc862631/<p><a href="https://digital.library.unt.edu/ark:/67531/metadc862631/"><img alt="Crystal structure of (3E,5E)-3,5-bis[4-(diethylazaniumyl)benzylidene]-1-methyl-4-oxopiperidin-1-ium trichloride dihydrate: a potential biophotonic material" title="Crystal structure of (3E,5E)-3,5-bis[4-(diethylazaniumyl)benzylidene]-1-methyl-4-oxopiperidin-1-ium trichloride dihydrate: a potential biophotonic material" src="https://digital.library.unt.edu/ark:/67531/metadc862631/thumbnail/"/></a></p><p>This article describes the crystal structure of the title compound, and examines application as an agent for locating cancer cells with two-photon excited fluorescence as as a potential agent for a photodynamic treatment of cancer. This article includes supporting information with computing details of the study.</p>Genome-wide analysis of the omega-3 fatty acid desaturase gene family in Gossypium2016-08-31T10:05:56-05:00https://digital.library.unt.edu/ark:/67531/metadc862692/<p><a href="https://digital.library.unt.edu/ark:/67531/metadc862692/"><img alt="Genome-wide analysis of the omega-3 fatty acid desaturase gene family in Gossypium" title="Genome-wide analysis of the omega-3 fatty acid desaturase gene family in Gossypium" src="https://digital.library.unt.edu/ark:/67531/metadc862692/thumbnail/"/></a></p><p>This article identifies and characterizes the omega-3 fatty acid desaturase gene family in Gossypium hirsutum, with an emphasis on identifying omega-3 fatty acid desaturase involved in cold temperature adaption.</p>HSI2/VAL1 PHD-like domain promotes H3K27 trimethylation to repress the expression of seed maturation genes and complex transgenes in Arabidopsis seedlings2016-08-31T10:05:56-05:00https://digital.library.unt.edu/ark:/67531/metadc862682/<p><a href="https://digital.library.unt.edu/ark:/67531/metadc862682/"><img alt="HSI2/VAL1 PHD-like domain promotes H3K27 trimethylation to repress the expression of seed maturation genes and complex transgenes in Arabidopsis seedlings" title="HSI2/VAL1 PHD-like domain promotes H3K27 trimethylation to repress the expression of seed maturation genes and complex transgenes in Arabidopsis seedlings" src="https://digital.library.unt.edu/ark:/67531/metadc862682/thumbnail/"/></a></p><p>This article studies the novel mutant allele hsi2-4, isolated in a genetic screen to identify Arabidopsis mutants with consitutively elevated expression of a glutathione S-transferase F8:luciferase reporter gene in Arabidopsis.</p>A deep transcriptomic analysis of pod development in the vanilla orchid (Vanilla planifolia)2016-08-31T10:05:56-05:00https://digital.library.unt.edu/ark:/67531/metadc862649/<p><a href="https://digital.library.unt.edu/ark:/67531/metadc862649/"><img alt="A deep transcriptomic analysis of pod development in the vanilla orchid (Vanilla planifolia)" title="A deep transcriptomic analysis of pod development in the vanilla orchid (Vanilla planifolia)" src="https://digital.library.unt.edu/ark:/67531/metadc862649/thumbnail/"/></a></p><p>This research article describes very large gene sequence datasets from vanilla pods at different times of development, representing different tissue types, including the seeds, hairs, and placental and mesocarp tissues within the pod.</p>Terpene Biosynthesis in Glandular Trichomes of Hop2015-02-06T09:38:11-06:00https://digital.library.unt.edu/ark:/67531/metadc499077/<p><a href="https://digital.library.unt.edu/ark:/67531/metadc499077/"><img alt="Terpene Biosynthesis in Glandular Trichomes of Hop" title="Terpene Biosynthesis in Glandular Trichomes of Hop" src="https://digital.library.unt.edu/ark:/67531/metadc499077/thumbnail/"/></a></p><p>Article on terpene biosynthesis in glandular trichomes of hop.</p>Co-localization of L-Phenylalanine Ammonia-Lyase and Cinnamate 4-Hydroxylase for Metabolic Channeling in Phenylpropanoid Biosynthesis2015-01-22T09:04:02-06:00https://digital.library.unt.edu/ark:/67531/metadc488182/<p><a href="https://digital.library.unt.edu/ark:/67531/metadc488182/"><img alt="Co-localization of L-Phenylalanine Ammonia-Lyase and Cinnamate 4-Hydroxylase for Metabolic Channeling in Phenylpropanoid Biosynthesis" title="Co-localization of L-Phenylalanine Ammonia-Lyase and Cinnamate 4-Hydroxylase for Metabolic Channeling in Phenylpropanoid Biosynthesis" src="https://digital.library.unt.edu/ark:/67531/metadc488182/thumbnail/"/></a></p><p>Article on the co-localization of L-phenylalanine ammonia-lyase and cinnamate 4-hydroxylase for metabolic channeling in phenylpropanoid biosynthesis.</p>Targeted down-regulation of cytochrome P450 enzymes for forage quality improvement in alfalfa (Medicago sativa L.)2015-01-22T09:04:02-06:00https://digital.library.unt.edu/ark:/67531/metadc488171/<p><a href="https://digital.library.unt.edu/ark:/67531/metadc488171/"><img alt="Targeted down-regulation of cytochrome P450 enzymes for forage quality improvement in alfalfa (Medicago sativa L.)" title="Targeted down-regulation of cytochrome P450 enzymes for forage quality improvement in alfalfa (Medicago sativa L.)" src="https://digital.library.unt.edu/ark:/67531/metadc488171/thumbnail/"/></a></p><p>Article on targeted down-regulation of cytochrome P450 enzymes for forage quality improvement in alfalfa (Medicago sativa L.).</p>Different mechanisms for phytoalexin induction by pathogen and wound signals in Medicago truncatula2015-01-22T09:04:02-06:00https://digital.library.unt.edu/ark:/67531/metadc488158/<p><a href="https://digital.library.unt.edu/ark:/67531/metadc488158/"><img alt="Different mechanisms for phytoalexin induction by pathogen and wound signals in Medicago truncatula" title="Different mechanisms for phytoalexin induction by pathogen and wound signals in Medicago truncatula" src="https://digital.library.unt.edu/ark:/67531/metadc488158/thumbnail/"/></a></p><p>Article on different mechanisms for phytoalexin induction by pathogen and wound signals in Medicago truncatula.</p>Proanthocyanidins - a final frontier in flavonoid research?2015-01-22T09:04:02-06:00https://digital.library.unt.edu/ark:/67531/metadc488173/<p><a href="https://digital.library.unt.edu/ark:/67531/metadc488173/"><img alt="Proanthocyanidins - a final frontier in flavonoid research?" title="Proanthocyanidins - a final frontier in flavonoid research?" src="https://digital.library.unt.edu/ark:/67531/metadc488173/thumbnail/"/></a></p><p>Article on proanthocyanidins -- a final frontier in flavonoid research?</p>Analysis of cDNA libraries from developing seeds of guar (Cyamopsis tetragonoloba (L.) Taub)2015-01-22T09:04:02-06:00https://digital.library.unt.edu/ark:/67531/metadc488178/<p><a href="https://digital.library.unt.edu/ark:/67531/metadc488178/"><img alt="Analysis of cDNA libraries from developing seeds of guar (Cyamopsis tetragonoloba (L.) Taub)" title="Analysis of cDNA libraries from developing seeds of guar (Cyamopsis tetragonoloba (L.) Taub)" src="https://digital.library.unt.edu/ark:/67531/metadc488178/thumbnail/"/></a></p><p>Article on the analysis of cDNA libraries from developing seeds of guar (Cyamopsis tetragonoloba (L.) Taub).</p>