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Theranostic Small-Molecule Prodrug Conjugates for Targeted Delivery and Controlled Release of Toll-like Receptor 7 Agonists (open access)

Theranostic Small-Molecule Prodrug Conjugates for Targeted Delivery and Controlled Release of Toll-like Receptor 7 Agonists

This article presents a novel class of chemically identical theranostic small-molecule prodrug conjugates (T-SMPDCs), [¹⁸/¹⁹F]F-TZ(PSMA)-LEGU-TLR7, for PSMA-targeted delivery and controlled release of toll-like receptor 7 (TLR7) agonists to elicit de novo immune response for cancer immunotherapy. The proof-of-concept biological evaluation presented demonstrates the potential of T-SMPDCs for cancer immunomodulatory therapies.
Date: June 28, 2022
Creator: Debnath, Sashi; Hao, Guiyang; Guan, Bing; Thapa, Pawan; Hao, Justin; Hammers, Hans et al.
Object Type: Article
System: The UNT Digital Library
[Minutes: Math & Science Academy Committee, June 10, 1987] (open access)

[Minutes: Math & Science Academy Committee, June 10, 1987]

Handwritten committee meeting minutes related to the creation of the Texas Academy of Mathematics and Science.
Date: June 10, 1987
Creator: unknown
Object Type: Text
System: The UNT Digital Library
[Letter from Ann Lupkowski to Jim Miller, June 14, 1989] (open access)

[Letter from Ann Lupkowski to Jim Miller, June 14, 1989]

Letter from Ann Lupkowski to Jim Miller, on June 14, 1989, congratulating him on the funding of the Texas Academy of Mathematics and Science by the Texas Legislature. She also mentions that she intends to apply for federal grants for projects for gifted and talented students.
Date: June 14, 1989
Creator: Lupkowski, Ann E.
Object Type: Letter
System: The UNT Digital Library
[Letter from Julian Stanley to Manus Donahue, June 13, 1989] (open access)

[Letter from Julian Stanley to Manus Donahue, June 13, 1989]

Letter from Julian Stanley to Manus Donahue, on June 13, 1989, welcoming him to the administrative team of the Texas Academy of Mathematics and Science, and offering a few suggestions on expanding opportunities for the students.
Date: June 13, 1989
Creator: Stanley, Julian C.
Object Type: Letter
System: The UNT Digital Library
[Letter from Julian Stanley to Rogers Redding, June 6, 1989] (open access)

[Letter from Julian Stanley to Rogers Redding, June 6, 1989]

Letter from Julian Stanley to Rogers Redding, on June 6, 1989, suggesting that the minimum number of credits needed for graduation be set at 48, to ease pressure from the students.
Date: June 6, 1989
Creator: Stanley, Julian C.
Object Type: Letter
System: The UNT Digital Library
[Letter from Ann Lupkowski to Rogers Redding, June 14, 1989] (open access)

[Letter from Ann Lupkowski to Rogers Redding, June 14, 1989]

Letter from Ann Lupkowski to Rogers Redding, on June 14, 1989, congratulating him on receiving funding for the Texas Academy of Mathematics and Science from the Texas Legislature, and offering a list of projects she hopes to undertake when she begins work at the University of North Texas.
Date: June 14, 1989
Creator: Lupkowski, Ann E.
Object Type: Letter
System: The UNT Digital Library
[Memo to Frank Kemerer, June 23, 1987] (open access)

[Memo to Frank Kemerer, June 23, 1987]

Memo to Frank Kemerer on June 23, 1987, concerning the meeting his Student Affairs Committee had with Richard Brown, of the Louisiana School for Math, Science and the Arts. Information on the Louisiana program, such as teachers, criteria for entrance, cost, and their beginning staff.
Date: June 23, 1987
Creator: unknown
Object Type: Letter
System: The UNT Digital Library
Texas Academy of Mathematics and Science Applicant Information (open access)

Texas Academy of Mathematics and Science Applicant Information

Information on the applicants to the Texas Academy of Mathematics and Science for the 1988 fall semester.
Date: June 9, 1988
Creator: Texas Academy of Mathematics and Science
Object Type: Report
System: The UNT Digital Library
Foreign Students Fueled 2% Rise in 1985 Graduate Science and Engineering Enrollment (open access)

Foreign Students Fueled 2% Rise in 1985 Graduate Science and Engineering Enrollment

Article from the National Science Foundation, noting that the 2% rise in 1985 graduate science and engineering enrollment was due to foreign students.
Date: June 12, 1987
Creator: National Science Foundation
Object Type: Article
System: The UNT Digital Library
The North Carolina School of Science and Mathematics (open access)

The North Carolina School of Science and Mathematics

Article by Charles R. Eilber detailing the North Carolina School of Science and Mathematics. He talks about the students, the instructional program, the residential program, support services, public services, the outcomes and costs, and the implications for education.
Date: June 1987
Creator: Eilber, Charles R.
Object Type: Article
System: The UNT Digital Library
[Memorandum from Frank Kemerer, June 1, 1987] (open access)

[Memorandum from Frank Kemerer, June 1, 1987]

Memorandum from Frank Kemerer to Julian Dunn, Barbara Jungjohan, Peter Lane, Betsy McGuire, Byron Medler, Bruce Meeks, and selected high school students and parents, on June 1, 1987, asking them to serve on a student affairs committee to implement the Texas Academy of Math and Science.
Date: June 1, 1987
Creator: Kemerer, Frank R.
Object Type: Letter
System: The UNT Digital Library
[Letter from William W. Youngblood to Frank Kemerer, June 19, 1987] (open access)

[Letter from William W. Youngblood to Frank Kemerer, June 19, 1987]

Letter from William W. Youngblood to Frank Kemerer, on June 19, 1987, sending him the Student Code of Conduct for the North Carolina School of Science and Mathematics. He draws attention to their attendance policy, and invites Kemerer to call him with any questions. The NCSSM Code of Conduct is also included.
Date: June 19, 1987
Creator: Youngblood, William W.
Object Type: Letter
System: The UNT Digital Library
State Residential High Schools for Mathematically Talented Youth (open access)

State Residential High Schools for Mathematically Talented Youth

Paper written by Julian C. Stanley, explaining how states can promote the preparation of more highly qualified students in mathematics.
Date: June 1987
Creator: Stanley, Julian C.
Object Type: Article
System: The UNT Digital Library
[Memorandum from Richard L. Simms to Jim Muro, June 18, 1987] (open access)

[Memorandum from Richard L. Simms to Jim Muro, June 18, 1987]

Memorandum from Richard L. Simms to Jim Muro, on June 18, 1987, concerning staffing needs for the Texas Academy of Mathematics and Science during the planning year.
Date: June 18, 1987
Creator: Simms, Richard L.
Object Type: Letter
System: The UNT Digital Library
[Letter to James R. Miller, June 16, 1987] (open access)

[Letter to James R. Miller, June 16, 1987]

Letter from Jane to James R. Miller, on June 16, 1987, informing him that arrangements have been made for Miller to fly to Austin and back to attend the bill-signing ceremony.
Date: June 16, 1987
Creator: unknown
Object Type: Letter
System: The UNT Digital Library
[Letter from H. Braughn Taylor to James R. Miller, June 3, 1987] (open access)

[Letter from H. Braughn Taylor to James R. Miller, June 3, 1987]

Letter from H. Braughn Taylor to James R. Miller, on June 3, 1987, sending him a Capital Improvements Analysis, the Budget Report of April 30, 1987 by major division of the school, and the endowment.
Date: June 3, 1987
Creator: Taylor, H. Braughn
Object Type: Letter
System: The UNT Digital Library
[Memorandum from Jim Muro to Alfred Hurley, June 18, 1987] (open access)

[Memorandum from Jim Muro to Alfred Hurley, June 18, 1987]

Memorandum from Jim Muro to Alfred Hurley, on June 18, 1987, laying out ideas on how to fund the Texas Academy of Mathematics and Science. Muro also mentions that they need to begin recruiting students within the next two months.
Date: June 18, 1987
Creator: Muro, James J.
Object Type: Letter
System: The UNT Digital Library
[Memorandum from Frank Kemerer, June 2, 1987] (open access)

[Memorandum from Frank Kemerer, June 2, 1987]

Memorandum from Frank Kemerer to Julian Dunn, Barbara Jungjohan, Peter Lane, Betsy McGuire, Byron Medler, Bruce Meeks, on June 2, 1987, informing them of the time and place of the first meeting of the Student Affairs Committee to Implement the Texas Academy of Math and Science.
Date: June 2, 1987
Creator: Kemerer, Frank R.
Object Type: Letter
System: The UNT Digital Library
[Executive Summary of A Proposal for the Establishment of a Texas Academy of Mathematics and Science at North Texas State University] (open access)

[Executive Summary of A Proposal for the Establishment of a Texas Academy of Mathematics and Science at North Texas State University]

Executive summary of a proposal for the establishment of a Texas Academy of Mathematics and Science at North Texas State University, including information on the purpose, rationale and need, a description of the academy, personnel, organizational structure, management, a budget summary, and expected outcomes.
Date: June 3, 1987
Creator: Miller, James R.
Object Type: Paper
System: The UNT Digital Library
[Memo from Rogers Redding to Alfred Hurley, June 22, 1988] (open access)

[Memo from Rogers Redding to Alfred Hurley, June 22, 1988]

Memo from Rogers Redding to Alfred Hurley, on June 22, 1988, informing him of the university's cooperation with the Texas Prefreshmen Engineering Preparation program, in regards to Hurley's hope to bring minority students into the Academy.
Date: June 22, 1988
Creator: Redding, Rogers W.
Object Type: Letter
System: The UNT Digital Library
[Letter from Frank Kemerer to Charles R. Eilber, June 8, 1987] (open access)

[Letter from Frank Kemerer to Charles R. Eilber, June 8, 1987]

Letter from Frank Kemerer to Charles R. Eilber, on June 8, 1987, asking that he send copies of policies related to student residential life, so that he can consider them as the chair of a student affairs committee.
Date: June 8, 1987
Creator: Kemerer, Frank R.
Object Type: Letter
System: The UNT Digital Library
[Two Articles on State Residential Schools for Mathematically Talented Youth] (open access)

[Two Articles on State Residential Schools for Mathematically Talented Youth]

Two articles on the advanced schools provided for gifted and talented students in North Carolina and Maryland.
Date: June 1987
Creator: Stanley, Julian C. & Eilber, Charles R.
Object Type: Article
System: The UNT Digital Library
[Memo to Frank Kemerer, June 23, 1987] (open access)

[Memo to Frank Kemerer, June 23, 1987]

Memo to Frank Kemerer concerning the meeting his Student Affairs Committee had with Richard Brown, of the Louisiana School for Math, Science and the Arts. It includes information on the Louisiana program, such as teachers, criteria for entrance, cost, and their beginning staff.
Date: June 23, 1987
Creator: unknown
Object Type: Letter
System: The UNT Digital Library
[Memo from Frank Kemerer, June 17, 1987] (open access)

[Memo from Frank Kemerer, June 17, 1987]

Memo from Frank Kemerer to Julia Dunn, Barbara Jungjohan, Peter Lane, Betsy McGuire, Bruce Meeks, and Byron Medler, on June 17, 1987, extending an invitation from Dr. Jean Schaake to meet with the director of the Louisiana School for Math, Science and the Arts.
Date: June 17, 1987
Creator: Kemerer, Frank R.
Object Type: Letter
System: The UNT Digital Library