Prokaryotic life on earth is manifested by its diversity and omnipresence. These microbes serve as natural sources of a large variety of compounds with the potential to serve the ever growing, medicinal, chemical and transportation needs of the human population. However, commercially viable production of these compounds can be realized only through significant improvement of the native production capacity of natural isolates. The most favorable way to achieve this goal is through the genetic manipulation of metabolic pathways that direct the production of these molecules. While random mutagenesis and screening have dominated the industrial production of such compounds in the past our increased understanding of microbial physiology over the last five decades has shifted this trend towards rational approaches for metabolic design. Major drivers of this trend include recombinant DNA technology, high throughput characterization of macromolecular cellular components, quantitative modeling for metabolic engine ring, targeted combinatorial engineering and synthetic biology. In this chapter we track the evolution of microbial engineering technologies from the black box era of random mutagenesis to the science and engineering-driven era of metabolic design.

Proposed budget for the Coastal Water Authority Red Bluff Water Treatment Plant in Harris County, Texas outlining projected income and expenditures, with supporting documentation.

Proposed budget for the Coastal Water Authority Lake Houston Facilities Project outlining projected income and expenditures, with supporting documentation.

This document provides information on the distribution of $580 million in monthly sales tax revenue to local government.

This document provides information on the impact of the Texas Poultry Industry to the economy.

"Included in this publication is information about bluebirds and cavity nesting birds, the proper placement of nest boxes and simple plans for building wood nest boxes should you choose to do so in the future" (p. 1).

Catalog of seasonal activities offered by City of Denton Parks and Recreation and the Denton Senior Center for adults aged 50+, including special events, programs, and classes. Some issues also include articles or messages from staffmembers about topics of interest to seniors.

This primer explores the workings of the wholesale markets for natural gas, electricity and oil, which are forms of energy that are of particular interest to the Federal Energy Regulatory Commission pursuant to its authority under the Natural Gas Act, the Federal Power Act, and the Interstate Commerce Act.

Training conducted as a part of the United Negro College Fund Special Programs/National Library of Medicine -HBCU ACCESS Project at Howard University, Washington, DC on November 20, 2010.

Training Manual updated for United Negro College Fund Special Programs Corporation/National Library of Medicine - HBCU ACCESS Project for Alcorn State University, Natchez, Mississippi, November 12, 2010

Environmental health focus with training conducted as part of the United Negro College Fund Special Programs Corporation/National Library of Medicine HBCU ACCESS Project at Winston-Salem State University, NC on November 10, 2010.

Training update with Environmental a health focus. Training conducted as part of the United Negro College Fund Special Programs Corporation/National Library of Medicine - HBCU ACCESS Project at the University of the District of Columbia, Washington, DC on November 2, 2010.

An environmental report on the Edwards Aquifer's habitat areas and species as part of the process of applying for an incidental take permit for endangered species.

This document contains information about the Texas Constitution and new amendments for the year 2011.

The Dry Cleaners Environmental Response Program was created in 2003 by House Bill 1366 (78th Legislature, Regular session) and codified in the Texas Health and Safety Code. This law is established new environmental standards for dry cleaners and a remediation fund to assist with the assessment and remediation of contamination caused by dry cleaning solvents.

This document provides rules, regulations, and responsibilities of contractors that have been given approved Edwards Aquifer protection plans or Contributing Zone plans and approval letters. (p. 1).

Guide describing requirements for the use of graywater and alternative on-site water by agricultural users.

This document is intended to familiarize readers with the approach for determining representative concentrations, defining exposure levels, and evaluating potential hot spots for ecological exposure pathways.

The main purpose of this guidance document is to help generators of industrial and hazardous waste follow state and federal requirements on classifying and coding these wastes, keeping proper records, and notifying the Texas Commission on Environmental Quality about the wastes, when required.

A travel guide to the Texas Historical Commission ten heritage trails areas with attraction information, photos, and maps.

Document providing summaries of all bills and joint resolutions passed by the Texas Legislature during the 2019 Regular Session, from January 8 through May 27.

Business plan developed by the Texas Lottery Commission including organizational information about the Commission as well as the projected business plan with objects, strategies, and action plans.

Proposed budget for the Coastal Water Authority outlining projected income and expenditures, with supporting documentation.

Agency strategic plan for the Texas Department of Information Resources describing the organization's planned services, activities, and other goals during fiscal years 2013 through 2017.