A letter report issued by the Government Accountability Office with an abstract that begins "Acquiring new systems on budget and on schedule is critically important in transitioning to the Next Generation Air Transportation System (NextGen). However, air traffic control modernization has been on GAO's high-risk list since 1995, in part due to acquisitions exceeding budget and schedule targets. The Federal Aviation Administration's (FAA) Air Traffic Organization (ATO) has responsibility for managing air traffic control acquisitions. GAO was asked to examine (1) ATO's goals, performance measures, and reporting for systems acquisitions; (2) the validity of ATO's performance measures; and (3) the implications of using ATO's performance measures to assess progress in transitioning to NextGen. To address these issues, GAO compared ATO's measures with attributes of successful performance measures, interviewed agency officials, and sought perspectives of aviation experts."

Can supersymmetric models with a moderate stop mass be made consistent with the negative Higgs boson searches at LEP, while keeping perturbative unification manifest? The NMSSM achieves this rather easily, but only if extra matter multiplets filling complete SU(5) representations are present at intermediate energies. As a concrete example which makes use of this feature, we give an analytic description of the phenomenology of a constrained NMSSM close to a Peccei-Quinn symmetry point. The related pseudo-Goldstone boson appears in decays of the Higgs bosons and possibly of the lightest neutralino, and itself decays into (b anti-b) and (tau anti-tau).

Correspondence issued by the Government Accountability Office with an abstract that begins "In 1960, Congress authorized the construction of the San Luis Unit of the Central Valley Project (CVP) in California. The CVP is a network of dams, canals, pumps, and other facilities providing water for multiple uses. Located south of the Sacramento-San Joaquin Delta, the San Luis Unit is a component of the CVP and was built jointly by the Department of the Interior's Bureau of Reclamation (Reclamation) and the state of California. The San Luis Unit stores and delivers water that is used for various purposes, including agriculture, municipal and industrial uses, and fish and wildlife needs. Four irrigation water districts in the San Luis Unit currently receive water from the CVP. Westlands is the largest of these districts, covering about three-quarters of the land in the San Luis Unit. The three smaller districts are Pacheco, Panoche, and San Luis. Reclamation has a water service contract with each irrigation water district to deliver CVP water to the district's farmers and other water users at a set rate per acre-foot. Existing water service contracts may be renewed for a period of no more than 25 years. The San Luis …

Comparing gene expression profiles over many different conditions has led to insights that were not obvious from single experiments. In the same way, comparing patterns of natural selection across a set of ecologically distinct species may extend what can be learned from individual genome-wide surveys. Toward this end, we show how variation in protein evolutionary rates, after correcting for genome-wide effects such as mutation rate and demographic factors, can be used to estimate the level and types of natural selection acting on genes across different species. We identify unusually rapidly and slowly evolving genes, relative to empirically derived genome-wide and gene family-specific background rates for 744 core protein families in 30 gamma-proteobacterial species. We describe the pattern of fast or slow evolution across species as the 'selective signature' of a gene. Selective signatures represent a profile of selection across species that is predictive of gene function: pairs of genes with correlated selective signatures are more likely to share the same cellular function, and genes in the same pathway can evolve in concert. For example, glycolysis and phenylalanine metabolism genes evolve rapidly in Idiomarina loihiensis, mirroring an ecological shift in carbon source from sugars to amino acids. In a broader context, …

This final report summarizes the work conducted under our three year DOE GTL grant ($459,402). The work involved a number of areas, including standardization, the Systems Biology Workbench, Visual Editors, collaboration with other groups and the development of new theory and algorithms. Our work has played a key part in helping to further develop SBML, the de facto standard for System Biology Model exchange and SBGN, the developing standard for visual representation for biochemical models. Our work has also made significant contributions to developing SBW, the systems biology workbench which is now very widely used in the community (roughly 30 downloads per day for the last three years, which equates to about 30,000 downloads in total). We have also used the DOE funding to collaborate extensively with nine different groups around the world. Finally we have developed new methods to reduce model size which are now used by all the major simulation packages, including Matlab. All in all, we consider the last three years to be highly productive and influential in the systems biology community. The project resulted in 16 peer review publications.

This report examines whether such as extension would violate the First Amendment's guarantee of freedom of speech.

This report has the following articles: (1) Deconstructing Microbes--metagenomic research on bugs in termites relies on new data analysis tools; (2) Popular Science--a nanomaterial research paper in Nano Letters drew strong interest from the scientific community; (3) Direct Approach--researchers employ an algorithm to solve an energy-reduction issue essential in describing complex physical system; and (4) SciDAC Special--A science journal features research on petascale enabling technologies.

This paper describes automated demand response (Auto-DR) activities, an innovative effort in California to ensure that DR programs produce effective and sustainable impacts. Through the application of automation and communication technologies coupled with well-designed incentives and DR programs such as Critical Peak Pricing (CPP) and Demand Bidding (DBP), Auto-DR is opening up the opportunity for many different types of buildings to effectively participate in DR programs. We present the results of Auto-DR implementation efforts by the three California investor-owned utilities for the Summer of 2007. The presentation emphasizes Pacific Gas and Electric Company's (PG&E) Auto-DR efforts, which represents the largest in the state. PG&E's goal was to recruit, install, test and operate 15 megawatts of Auto-DR system capability. We describe the unique delivery approaches, including optimizing the utility incentive structures designed to foster an Auto-DR service provider community. We also show how PG&E's Critical Peak Pricing (CPP) and Demand Bidding (DBP) options were called and executed under the automation platform. Finally, we show the results of the Auto-DR systems installed and operational during 2007, which surpassed PG&E's Auto-DR goals. Auto-DR is being implemented by a multi-disciplinary team including the California Investor Owned Utilities (IOUs), energy consultants, energy management control system …

Coincident measurement of the Auger electron and fragmention momenta emitted after carbon core-level photoionization of acetylenehas yielded new understanding of how the dication fragments. Ab initiocalculations and experimental data, including body-frame Auger angulardistributions, are used to identify the parent electronic states andtogether yield a comprehensive map of the dissociation pathways whichinclude surface crossings and barriers to direct dissociation. The Augerangular distributions show evidence of core-holelocalization.

The purpose of this study is to report on the results of a preliminary modeling framework to investigate the causes of the large hydraulic gradient north of Yucca Mountain. This study builds on the Saturated Zone Site-Scale Flow and Transport Model (referenced herein as the Site-scale model (Zyvoloski, 2004a), which is a three-dimensional saturated zone model of the Yucca Mountain area. Groundwater flow was simulated under natural conditions. The model framework and grid design describe the geologic layering and the calibration parameters describe the hydrogeology. The Site-scale model is calibrated to hydraulic heads, fluid temperature, and groundwater flowpaths. One area of interest in the Site-scale model represents the large hydraulic gradient north of Yucca Mountain. Nearby water levels suggest over 200 meters of hydraulic head difference in less than 1,000 meters horizontal distance. Given the geologic conceptual models defined by various hydrogeologic reports (Faunt, 2000, 2001; Zyvoloski, 2004b), no definitive explanation has been found for the cause of the large hydraulic gradient. Luckey et al. (1996) presents several possible explanations for the large hydraulic gradient as provided below: The gradient is simply the result of flow through the upper volcanic confining unit, which is nearly 300 meters thick near the …

We describe our efforts to understand large-scale (10's-100's kpc) relativistic jet systems through observations of the highest-redshift quasars. Results from a VLA survey search for radio jets in {approx} 30 z > 3.4 quasars are described along with new Chandra observations of 4 selected targets.

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A letter report issued by the Government Accountability Office with an abstract that begins "The 2006 U.S. National Security Strategy stated that the United States faces challenges from Iran, including Iran's proliferation efforts and involvement in international terrorism. To address these concerns, the United States employs a range of tools, including diplomatic pressure, a military presence in the Gulf, and sanctions. A U.S. sanction is a unilateral restriction or condition on economic activity imposed by the United States for reasons of foreign policy or national security. We were asked to review (1) U.S. sanctions targeting Iran and their implementation, (2) reported sanction impacts, and (3) factors limiting sanctions. To conduct the review, we assessed trade and sanction data, information on Iran's economy and energy sector, and U.S. and international reports on Iran, and discussed sanctions with U.S. officials and Iran experts."

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Using magnetohydrodynamic (MHD) adaptive mesh refinement simulations, we study the formation and early evolution of disk galaxies with a magnetized interstellar medium. For a 10{sup 10} M{sub {circle_dot}} halo with initial NFW dark matter and gas profiles, we impose a uniform 10{sup -9} G magnetic field and follow its collapse, disk formation and evolution up to 1 Gyr. Comparing to a purely hydrodynamic simulation with the same initial condition, we find that a protogalactic field of this strength does not significantly influence the global disk properties. At the same time, the initial magnetic fields are quickly amplified by the differentially rotating turbulent disk. After the initial rapid amplification lasting {approx} 500 Myr, subsequent field amplification appears self-regulated. As a result, highly magnetized material begin to form above and below the disk. Interestingly, the field strengths in the self-regulated regime agrees well with the observed fields in the Milky Way galaxy both in the warm and the cold HI phase and do not change appreciably with time. Most of the cold phase shows a dispersion of order ten in the magnetic field strength. The global azimuthal magnetic fields reverse at different radii and the amplitude declines as a function of radius …

Testimony issued by the Government Accountability Office with an abstract that begins "When oil spills occur in U.S. waters, federal law places primary liability on the vessel owner or operator--that is, the responsible party--up to a statutory limit. As a supplement to this "polluter pays" approach, a federal Oil Spill Liability Trust Fund administered by the Coast Guard pays for costs when a responsible party does not or cannot pay. This testimony is based on GAO's September 2007 report on oil spill costs and select program updates on the recent San Francisco spill. Specifically, it answers three questions: (1) How many major spills (i.e., at least $1 million) have occurred since 1990, and what is their total cost? (2) What factors affect the cost of spills? and (3) What are the implications of major oil spills for the Oil Spill Liability Trust Fund?"

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The interaction of ultra-high power picosecond laser pulses with solid targets is of interest both for benchmarking the results of hybrid particle in cell (PIC) codes and also for applications to re-entrant cone guided fast ignition. We describe the construction of novel targets in which copper/titanium wires are formed into 'nail-like' objects by a process of melting and micromachining, so that energy can be reliably coupled to a 24 {micro}m diameter wire. An extreme-ultraviolet image of the interaction of the Titan laser with such a target is shown.

We have studied detailed nucleosynthesis in the shocked surface layers of an oxygen-neon-magnesium core collapse supernova with an eye to determining whether the conditions are suitable for r-process nucleosynthesis. We find no such conditions in an unmodified model, but do find overproduction of N=50 nuclei (previously seen in early neutron-rich neutrino winds) in amounts that, if ejected, would pose serious problems for Galactic chemical evolution.

2007 was a year of progress and challenges for the Office of the Chief Financial Officer (OCFO). I believe that with the addition of a new Controller, the OCFO senior management team is stronger than ever. With the new Controller on board, the senior management team spent two intensive days updating our strategic plan for the next five years ending in 2012, while making sure that we continue to execute on our existing strategic initiatives. In 2007 the Budget Office, teaming with Human Resources, worked diligently with our colleagues on campus to reengineer the Multi-Location Appointment (MLA) process, making it easier for our Principal Investigators (PIs) to work simultaneously between the Laboratory and UC campuses. The hiring of a point-of-contact in Human Resources to administer the program will also make the process flow smoother. In order to increase our financial flexibility, the OCFO worked with the Department of Energy (DOE) to win approval to reduce the burden rates on research and development (R&D) subcontracts and Intra-University Transfers (IUT). The Budget Office also performed a 'return on investment' (ROI) analysis to secure UCRP funding for a much needed vocational rehabilitation counselor. This new counselor now works with employees who are on …

Here we discuss evolution and broad-band emission of compact (< kpc) lobes in young radio sources. We propose a simple dynamical description for these objects, consisting of a relativistic jet propagating into a uniform gaseous medium in the central parts of an elliptical host. In the framework of the proposed model, we follow the evolution of ultrarelativistic electrons injected from a terminal hotspot of a jet to expanding lobes, taking into account their adiabatic energy losses as well as radiative cooling. This allows us to discuss the broad-band lobe emission of young radio sources. In particular, we argue that the observed spectral turnover in the radio synchrotron spectra of these objects cannot originate from the synchrotron self-absorption process but is most likely due to free-free absorption effects connected with neutral clouds of interstellar medium engulfed by the expanding lobes and photoionized by active centers. We also find a relatively strong and complex high-energy emission component produced by inverse-Compton up-scattering of various surrounding photon fields by the lobes electrons. We argue that such high energy radiation is strong enough to account for several observed properties of GHz-peaked-spectrum (GPS) radio galaxies at UV and X-ray frequencies. In addition, this emission is expected …

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Correspondence issued by the Government Accountability Office with an abstract that begins "At an October 30, 2007, hearing before the subcommittee on U.S. efforts to secure, stabilize, and rebuild Iraq, several members requested additional information on international donors' pledges to reconstruction and stabilization efforts in Iraq. This correspondence provides updated information on the amounts of loans and grants pledged by each donor country, as well as the status of those pledges."