This special report, the second of our neuroscience series, discusses the field of neural grafting into the brain and spinal cord to treat neurological disorders. It describes the technology of neural grafting, the neurological conditions that it may be used to treat, and the patient populations that are affected. Also, the legal and ethical issues raised by the development of neural grafting techniques are discussed. The report includes a range of options for congressional action related to the Federal funding of transplantation research using human fetal tissue, the adequacy of existing Federal laws and regulations regarding the use of human fetal tissue, and the role of the Federal Government in guiding the development and promoting the safety and efficacy of neural grafting procedures.

This background paper, OTA sought the contributions of abroad spectrum of knowledgeable individuals and organizations. Some provided information, others reviewed drafts. OTA gratefully acknowledges their contributions of time and intellectual effort. As with all OTA studies, the content of this background paper is the sole responsibility of the Office of Technology Assessment and does not necessarily represent the views of our advisors or reviewers.

This OTA report was requested by the House Committee on Science, Space, and Technology, the House Subcommittee on Transportation and Hazardous Materials, Committee on Energy and Commerce, and the House Subcommittee on Regulation, Business Opportunities and Energy, Committee on Small Business. The report evaluates medical waste issues in the broader context of a waste management policy for the Nation. Waste reduction and recycling options for medical waste management, as well as incineration and non-incineration treatment alternatives are examined.

This report describes the issues associated with genetic monitoring and screening in the workplace. It examines the technologies used, analyzes the legal framework for the use of such tests, assesses the ethical issues inherent in the use of these tools in the workplace setting, describes how genetic information is conveyed by a genetic counselor, and, based on an OTA survey of 1,500 U.S. companies and the largest unions, evaluates the current and future use of genetic monitoring and screening in the workplace.