Laboratory mechanical tests were conducted to evaluate AE during uniaxial tensile, fracture and fatigue crack growth in A533B pressure vessel steel. The A533B steel included two heats of Class 1, one heat of Class 2 and a weldment made for the Heavy Section Steel Technology (HSST) Program. Specimen types included uniaxial tensile specimens, size 2 compact tension specimens for fatigue crack growth and fracture tests, and a single-edge notch specimen also for fatigue crack growth through material that was uniformly strained 3% prior to fatigue testing. In addition, AE monitoring was conducted on the HSST V-7B 6-inch thick pressure vessel test. AE data were partitioned into four ranges of signal amplitude and rise time. All the AE data were analyzed, with respect to mechanical behavior of A533B steel. Linear elastic fracture mechanics analysis methods were used to relate AE parameters to fracture and fatigue crack growth parameters. AE data from the V-7B vessel test were correlated with stress intensity factor and crack opening displacement. AE data from the fatigue crack growth tests were investigated using models based on fatigue crack growth rate, fatigue crack area and theoretical crack tip plastic zone size.