This dissertation describes an alternative method of measuring the W boson mass in D0 experiment. Instead of extracting M{sub W} from the fitting of W {yields} e{nu} fast Monte Carlo simulations to W {yields} e{nu} data as in the standard method, we make the direct fit of transverse mass between W {yields} e{nu} data and Z {yields} ee data. One of the two electrons from Z boson is treated as a neutrino in the calculation of transverse mass. In ratio method, the best fitted scale factor corresponds to the ratio of W and Z boson mass (M{sub W}/M{sub Z}). Given the precisely measured Z boson mass, W mass is directly fitted from W {yields} e{nu} and Z {yields} ee data. This dissertation demonstrates that ratio method is a plausible method of measuring the W boson mass. With the 1 fb{sup -1} D0 Run IIa dataset, ratio method gives M{sub W} = 80435 {+-} 43(stat) {+-} 26(sys) MeV.

Sum frequency generation (SFG) vibrational spectroscopy was used to investigate the interfacial properties of several amino acids, peptides, and proteins adsorbed at the hydrophilic polystyrene solid-liquid and the hydrophobic silica solid-liquid interfaces. The influence of experimental geometry on the sensitivity and resolution of the SFG vibrational spectroscopy technique was investigated both theoretically and experimentally. SFG was implemented to investigate the adsorption and organization of eight individual amino acids at model hydrophilic and hydrophobic surfaces under physiological conditions. Biointerface studies were conducted using a combination of SFG and quartz crystal microbalance (QCM) comparing the interfacial structure and concentration of two amino acids and their corresponding homopeptides at two model liquid-solid interfaces as a function of their concentration in aqueous solutions. The influence of temperature, concentration, equilibration time, and electrical bias on the extent of adsorption and interfacial structure of biomolecules were explored at the liquid-solid interface via QCM and SFG. QCM was utilized to quantify the biological activity of heparin functionalized surfaces. A novel optical parametric amplifier was developed and utilized in SFG experiments to investigate the secondary structure of an adsorbed model peptide at the solid-liquid interface.

We report the result of a search for the pair production of the lightest supersymmetric partner of the top quark ({tilde t}{sub 1}) in 5.4 {+-} 0.3 fb{sup -1} of data from the D0 detector at a p{bar p} center-of-mass energy of 1.96 TeV at the Fermilab Tevatron collider. The scalar top quarks are assumed to decay into a b quark, a charged lepton and a scalar neutrino ({tilde {nu}}), and the search is performed in the electron plus muon final state. No significant excess of events above the standard model prediction is detected and new exclusion limits at the 95% C.L. are set for a portion of the (m{sub {tilde t}{sub 1}}, m{sub {tilde {nu}}}) mass plane.

MINOS is a long baseline neutrino oscillation experiment based at the Fermi National Accelerator Laboratory in Illinois, USA. The experiment was designed to study neutrino oscillation phenomena. The {nu}{sub {mu}} beam produced by the NuMI beam facility at FNAL is used along with two functionally identical detectors. The Near Detector at FNAL and a Far Detector 735 km away in the Soudan Underground Laboratory in northern Minnesota. Comparison of the observed spectra of neutrinos at the two detectors provides the evidence for neutrino oscillations. This thesis presents work on the postulated phenomena of sterile neutrinos. Oscillations between active and sterile neutrinos will lead to a deficit in the expected rate of measured Neutral Current interactions at the Far Detector. A technique for selecting Neutral Current events utilizing an Artificial Neural Network is presented with resulting overall efficiency of 91.1% and purity of 66.0%. A method of predicting the expected Charged and Neutral Current energy spectra at the Far Detector given the data recorded at the Near Detector is presented. A model to search for oscillations between sterile and active neutrinos is developed. Sources of systematic uncertainty that can effect the results of the analysis are discussed. The analysis developed is …

This dissertation measures the t{bar t} production cross section at the Run II CDF detector using data from early 2001 through March 2007. The Tevatron at Fermilab is a p{bar p} collider with center of mass energy {radical}s = 1.96 TeV. This data composes a sample with a time-integrated luminosity measured at 2.2 {+-} 0.1 fb{sup -1}. A system of learning machines is developed to recognize t{bar t} events in the 'lepton plus jets' decay channel. Support Vector Machines are described, and their ability to cope with a multi-class discrimination problem is provided. The t{bar t} production cross section is then measured in this framework, and found to be {sigma}{sub t{bar t}} = 7.14 {+-} 0.25 (stat){sub -0.86}{sup +0.61}(sys) pb.