Temperatures as low as 42 C, maintained for a little as 25 minutes, inactivate {approx}25% of HIV. Furthermore, human immunodeficiency virus (HIV)-infected T-cells are more sensitive to heat than healthy lymphocytes and susceptibility increases when the cells are pre-sensitized by exposure to tumor necrosis factor. Thus, induction of a whole-body hyperthermia, or hyperthermia specifically limited to tissues having a high viral load, are potential antiviral therapies for acquired immunodeficiency disease (AIDS). Accordingly, we incorporated therapeutic hyperthermia into an existing mathematical model which evaluates the interaction between HIV and CD4{sup +} T cells. Given the assumptions and limitations of this model, the results indicate that a daily therapy, reducing the population of actively infected cells by 40% or infectious virus by 50%, would effectively reverse the depletion of T cells. In contrast, a daily reduction of 20% of either actively infected cells or infectious virus would have a marginal effect. However, reduction by 20% of both actively infected cells and infectious virus could restore T cell numbers, assuming that permanent damage had not been inflicted on the thymus. Whole-body hyperthermia seems unlikely to be clinically useful, unless it can be induced non-invasively without general anesthesia. In contrast, heating directed specifically to …

A major part of the work in this quarter was on the combustor tests in task 2. Three of the six planned tests in this task were completed. The first two were parametric tests of nominal one shift, (8 hour) duration on coal. Due to failure of the UV detector in the first test only several hours of coal fired operation were completed. In the second test, coal fired operation continued for the planned one shift until the 4 ton coal bin was empty. After reviewing this work with DOE, it was decided to focus the remaining test on longer duration operation with each test at one optimum condition. The third test was planned for two shift coal fired operation. Due to a problem with the pilot gas ignitor, combustion was delayed by 5 hours from 7 AM to Noon. As a result coal fired operation was limited to one shift between 3 PM and 11 PM. Throughout this period the combustor remained at one fixed condition with the use of computer control. Results for these three tests are presented in this report. Most of the work on the task 4 design and cost of a 20 MW combined gas-steam …

This Reference Book contains a current copy of the Clean Water Act (excluding Section 404) and those regulations that implement the statutes and appear to be most relevant to US Department of Energy (DOE) activities. The document is provided to DOE and contractor staff for informational purposes only and should not be interpreted as legal guidance. Updates that include important new requirements will be provided periodically. Questions concerning this Reference Book may be directed to Mark Petts, EH-231 (202/586-2609).

The objectives of this secondary oil recovery project involving the Carter sandstone in northwest Alabama are: (1) To increase the ultimate economic recovery of oil from the Carter reservoirs, thereby increasing domestic reserves and lessening US dependence on foreign oil; (2) To extensively model, test, and monitor the reservoirs so their management is optimized; and (3) To assimilate and transfer the information and results gathered to other US oil companies to encourage them to attempt similar projects. Start-up water injection began on 0 1/12/93 at the Central Bluff Field, and daily operations began on 01/13/93. These operations include monitoring wellhead pressures at the injector and two producers, and injection water treatment. Water injection was running 200-300 bbl/day at the end of February. Once the unit is pressured-up well testing will be performed. Unitization was approved on 03/01/93.b. For the North Fairview Field correlations and log analyses were used to determine the fluid and rock properties. A summary of these properties is included in Table 1. The results of the log analysis were used to construct the hydrocarbon pore volume map shown on Figure 1. The map was planimetered to determine original oil-in-place (OOIP) values and the hydrocarbon pore volume by …

This report contains the following appendices: Appendix A - Requirements for Undergraduate Level; Appendix B - Requirements for Graduate Level; Appendix C - Graduate Degree In Environmental Engineeringat New Mexico State University; Appendix D - Non-degree Certificate program; Appendix E - Curriculum for Associate Degree Program in Radioactive Hazardous Waste Materials; Appendix F - Curriculum for NCC Program in Earth Environmental Sciences; Appendix G - Brochure of 1992 Teleconference Series; Appendix H - Sites for Hazardous/Radioactive Waste Management Series; Appendix I - WERC Interactive Television Courses; Appendix J - WERC Research Seminar Series Brochures; Appendix K - Summary of Technology Development of the Third Year; Appendix L - List of Major Publications Resulting From WERC; Appendix M - Types of Equipment at WERC Laboratories; and Appendix N - WERC Newsletter Examples.

Clean Coal Technology (CCT) implies the use of coal in an environmentally acceptable manner. Coal combustion results in the emission of oxides of nitrogen (NO[sub x]), which are precursors of both acid rainand ozone formation. The primary objective of this CCT project is to evaluate the use of Gas Reburning and Low NO[sub x] Burners (GR-LNB) for NO[sub x] emission control from a wall fired boiler. It is anticipated that, if the demonstration is successful, the GR-LNB technology could become commercialized during the 1990's and will be capable of (1) achieving significant reduction in the emissions of nitrogen oxides and sulfur dioxide (another acid rain precursor) from existing facilities to minimize environmental impacts such as transboundary and interstate pollution and/or (2) providing for future energy needs in an environmentally acceptable manner. Low NO[sub x] burners are designed to delay the mixing of the coal fuel with combustion air to minimize the NO[sub x] formation. Typically, one may obtain up to 50% reduction in NO[sub x] emissions through the use of LNB. For LNB applications, the technology is developed and a number of LNB designs are commercially available. With GR, about 80--85 percent of the coal fuel is fired in the …

Atmospheric transport and diffusion models have been developed by the Environmental Technology Section (ETS) of the Savannah River Technology Center to calculate the location and concentration of toxic or radioactive materials during an accidental release at the Savannah River Site (SRS). The output from these models has been used to support initial on-site and off-site emergency response activities such as protective action decision making and field monitoring coordination. These atmospheric transport and diffusion models have been incorporated into an automated computer-based system called the (Weather Information and Display) System and linked to real-time meteorological and radiological monitoring instruments to provide timely information for these emergency response activities (Hunter, 1990). This report documents various aspects of the WIND system.

Radioiodine, which is the collective term for all radioactive isotopes of the element iodine, is formed at the Savannah River Site (SRS) principally as a by-product of nuclear reactor operations. Part of the radioiodine is released to the environment during reactor and reprocessing operations at the site. The purpose of this report is to provide an introduction to radioiodine production and disposition, its status in the environment, and the radiation dose and health risks as a consequence of its release to the environment around the Savannah River Plant. A rigorous dose reconstruction study is to be completed by thee Center for Disease Control during the 1990s.

The objective of this project is to evaluate and demonstrate a cost effective emission control technology for acid rain precursors, oxides of nitrogen (NO[sub x]) and sulfur (SO[sub x])on two coal fired utility boilers in Illinois. The units selected are representative of pre-NSPS design practices: tangential and cyclone fired. The specific objectives are to demonstrate reductions of 60 percent in NO[sub x] and 50 percent in SO[sub x] emissions, by a combination of two developed technologies, gas reburning (GR) and sorbent injection (SI). With GR, about 80--85 percent of the coal fuel is fired in the primary combustion zone. The balance of the fuel is added downstream as natural gas to create a slightly fuel rich environment in which NO[sub x]is converted to N[sub 2]. The combustion process is completed by overfire air addition. SO[sub x] emissions are reduced by injecting dry sorbents (usually calcium based) into the upper furnace. The sorbents trap SO[sub x] as solid sulfates that are collected in the particulate control device. This project is conducted in three phases at each site: (1) Design and Permitting, (2) Construction and Startup, and (3) Operation, Data Collection, Reporting and Disposition. Technology transfer to industry is accomplished through the …

This is the sixth quarterly report for this project and it covers work performed on Phase 3a of the project from February 1, 1992 through April 30, 1992. Extension of the parametric test period through June 1992 provides an opportunity to regain most of the schedule slippage, but only if the modifications needed for continuous operation of the CZD system are installed concurrent with the extended test period. These modifications include automation of the lime preparation and transfer system, automatic injection control, and related instrumentation and controls as necessary to integrate the operation of the CZD system with Seward Station Boiler No. 15. Early installation of these modifications would permit testing, debugging and adjustment of the automatic control system during the parametric test period. Results of current testing indicate that considerable testing and adjustment will be required to optimize operation of the CZD system after it is automated for continuous operation. Therefore, we intend to incorporate in Phase 3a(parametric testing) the system modifications needed for continuous automatic operation that were originally included in Phase 3b. Phase 3b would then be limited only to the one-year continuous demonstration.

It is concluded that the laboratory tests should be conducted at high levels of SO[sub 3] such that the resulting resistivity is in the range of 10[sup 7]--10[sup 8] ohm-cm. There are several reasons leading to this conclusion. At SO[sub 3] concentrations of 30 ppM and greater, the curves for both dew point and resistivity are relatively flat so that changes in gas phase SO[sub 3] will have minimal impact on particle characteristics. In addition, the electrostatic forces are relatively flat in this range so that changes in flue gas conditions will that result in a change in resistivity by up to two orders of magnitude will have little effect on the magnitude of reentrainment. Finally, at the very low resistivity conditions, reentrainment will be the highest. Since the purpose of the laboratory resistivity tests is to determine the relative ability of the various additives to reduce resistivity, the greater the reentrainment, the easier it will be to measure an improvement. Tests were conducted by first operating at baseline conditions with no additives and then repeating the test with additives. The data collected during each test includes the resistivity of the material, thickness of the collected dust layer, and subjective …

Progress was achieved in four areas: development of surface supported Group 5 metal organometallic compounds for catalytic arene hydrogenation, isolation and reactivity of possible intermediates in catalytic arene hydrogenation, synthesis and characterization of new d[sup 0]-metal hydride compounds, and stoichiometric reactivity of d[sup 0] metal hydrido, aryloxide compounds. (DLC)

A microjet reactor coupled to a VUV photoionization time-of-flight mass spectrometer has been used to obtain species measurements during high temperature pyrolysis and oxidation of a wide range of hydrocarbon compounds ranging from allene and acetylene to cyclohexane, benzene and toluene. Initial work focused on calibration of the technique, optimization of ion collection and detection and characterization of limitations. Using the optimized technique with 118 nm photoionization, intermediate species profiles were obtained for analysis of the hydrocarbon pyrolysis and oxidation mechanisms. The soft'' ionization, yielding predominantly molecular ions, allowed the study of reaction pathways in these high temperature systems where both sampling and detection challenges are severe. Work has focused on the pyrolysis and oxidative pyrolysis of aliphatic and aromatic hydrocarbon mixtures representative of coal pyrolysis and hydropyrolysis products. The detailed mass spectra obtained during pyrolysis and oxidation of hydrocarbon mixtures is especially important because of the complex nature of the product mixture even at short residence times and low primary reactant conversions. The combustion community has advanced detailed modeling of pyrolysis and oxidation to the C4 hydrocarbon level but in general above that size uncertainties in rate constant and thermodynamic data do not allow us to a priori predict …

Starting from free relativistic particles whose position and velocity can only be measured to a precision < [Delta]r[Delta]v > [equivalent to] [plus minus] k/2 meter[sup 2]sec[sup [minus]1] , we use the relativistic conservation laws to define the relative motion of the coordinate r = r[sub 1] [minus] r[sub 2] of two particles of mass m[sub 1], m[sub 2] and relative velocity v = [beta]c = [sub (k[sub 1] + k[sub 2]])/ [sup (k[sub 1] [minus] k[sub 2]]) in terms of conic section equation v[sup 2] = [Gamma] [2/r [plus minus] 1/a] where +'' corresponds to hyperbolic and [minus]'' to elliptical trajectories. Equation is quantized by expressing Kepler's Second Law as conservation of angular niomentum per unit mass in units of k. Principal quantum number is n [equivalent to] j + [1/2] with square'' [sub T[sup 2]]/[sup A[sup 2]] = (n [minus]1)nk[sup 2] [equivalent to] [ell][sub [circle dot]]([ell][sub [circle dot]] + 1)k[sup 2]. Here [ell][sub [circle dot]] = n [minus] 1 is the angular momentumquantum number for circular orbits. In a sense, we obtain spin'' from this quantization. Since [Gamma]/a cannot reach c[sup 2] without predicting either circular or asymptotic velocities equal to the limiting velocity for particulate motion, we can …

A large percentage of the radioactivity released to the environment by operations at the Savannah River Site (SRS) is due to tritium. Because of the relative importance of the releases of tritium from SRS facilities through the groundwater to the environment, periodic evaluation and documentation of the facility operational status, proposed corrective actions, and projected changes/reductions in tritium releases are justified. Past, current, and projected tritium releases from the F and H Area Seepage Basins and the Solid Waste Disposal Facilities (SWDF) to Fourmile Branch are described. Each section provides a brief operational history along with the current status and proposed corrective actions. A conceptual model and quantitative estimates of tritium release from the facilities into the groundwater and the environment are developed. Tritium releases from the F and H Area Seepage Basins are declining and will be further reduced by the implementation of a groundwater corrective action required by the Resource Conservation and Recovery Act (RCRA). Tritium releases from the SWDF have been relatively stable over the past 10 years. It is anticipated that SWDF tritium releases to Fourmile Branch will remain approximately at current levels for at least 10--20 years. Specific characterization activities are recommended to allow an …

The Electrochemical Technology Program at Argonne National Laboratory (ANL) provides technical and programmatic support to DOE's Electric and Hybrid Propulsion Division (DOE-EHP). The goal of DOE-EHP is to advance promising electric-vehicle (EV) propulsion technologies to levels where industry will continue their commercial development and thereby significantly reduce air pollution and petroleum consumption due to the transportation sector of the economy. In support of this goal, ANL provides research, development, testing/evaluation, post-test analysis, modeling, and project management on advanced battery technologies for DOE-EHP. This report summarizes the battery-related activities undertaken during the period of January 1, 1993 through March 31, 1993. In this report, the objective, background, technical progress, and status are described for each task. The work is organized into the following task areas: 1.0 Project Management; 2.0 Sodium/Metal Chloride R D; 3.0 Microreference Electrodes for Lithium/Polymer Batteries.

The research was in the area of solid cluster compounds containing metal clusters. Two classes of materials were studied: those based on solutions formed by dissolving LiMo[sub 3]Se[sub 3] in polar solvents, and those based on M[sub 6]X[sub 8] clusters. The cluster phases were synthesized and their properties examined. Nb[sub 6]I[sub 11] and Mo[sub 6]X[sub 8] were also studied.

Our work on the immunobiology of tumors induced in normal mice by non-ionizing radiation and chemical carcinogens has previously demonstrated a correlation between MHC molecule expression and the immunogenicity of tumors in a transplanted syngeneic host. Such that immunogenic or regressive tumors were found to demonstrate higher constitutive or inducible levels of MHC expression, while most virulent, aggressive tumors exhibited a low level of MHC Class I expression. We attributed much of the control of MHC molecule expression by antigen-bearing tumors and normal cells to the immunological status of the host since the host must provide the appropriate stimulus to enhance MHC antigen expression by the invading tumor. Our results with UVR-induced tumors suggested that a significant role is played by the T-cell lymphokine, [gamma]-interferon ([gamma]IFN), in the modulation of MHC molecule expression in vivo. Virulent tumors, induced by boneseeking radionuclides, may be refractory to [gamma]IFN stimulation of MHC molecule expression. It is also possible that certain tumors might be fully responsive to the Class I modulatory influences by [gamma]IFN, but exhibit a reduced capacity to stimulate the synthesis of this lymphokine by host T cells. We present experiments designed to : Describe the virulence, latency period, and transplantation characteristics …

The purpose of the Environmental Implementation Plan (EIP) is to show the current and future (five years) environmental plans from individual site organizations and divisions, as well as site environmental programs and initiatives which are designed to protect the environment and meet or exceed changing environmental/regulatory requirements. Communicating with site organizations, departments, and committees is essential in making the site's environmental-planning process work. The EIP gives the site the what, when, how, and why for environmental requirements. Through teamwork and proactive planning, a partnership for environmental excellence is formed to achieve the site vision for SRS to become the recognized model for Environmental Excellence in the Department of Energy's Nuclear Weapons Complex.

A weekly publication, the Texas Register serves as the journal of state agency rulemaking for Texas. Information published in the Texas Register includes proposed, adopted, withdrawn and emergency rule actions, notices of state agency review of agency rules, governor's appointments, attorney general opinions, and miscellaneous documents such as requests for proposals. After adoption, these rulemaking actions are codified into the Texas Administrative Code.

A weekly publication, the Texas Register serves as the journal of state agency rulemaking for Texas. Information published in the Texas Register includes proposed, adopted, withdrawn and emergency rule actions, notices of state agency review of agency rules, governor's appointments, attorney general opinions, and miscellaneous documents such as requests for proposals. After adoption, these rulemaking actions are codified into the Texas Administrative Code.

A weekly publication, the Texas Register serves as the journal of state agency rulemaking for Texas. Information published in the Texas Register includes proposed, adopted, withdrawn and emergency rule actions, notices of state agency review of agency rules, governor's appointments, attorney general opinions, and miscellaneous documents such as requests for proposals. After adoption, these rulemaking actions are codified into the Texas Administrative Code.

A weekly publication, the Texas Register serves as the journal of state agency rulemaking for Texas. Information published in the Texas Register includes proposed, adopted, withdrawn and emergency rule actions, notices of state agency review of agency rules, governor's appointments, attorney general opinions, and miscellaneous documents such as requests for proposals. After adoption, these rulemaking actions are codified into the Texas Administrative Code.

A weekly publication, the Texas Register serves as the journal of state agency rulemaking for Texas. Information published in the Texas Register includes proposed, adopted, withdrawn and emergency rule actions, notices of state agency review of agency rules, governor's appointments, attorney general opinions, and miscellaneous documents such as requests for proposals. After adoption, these rulemaking actions are codified into the Texas Administrative Code.