This Report, the first of the neuroscience series, discusses the risks posed by neurotoxic substances—substances that can adversely affect the nervous system—and evaluates the Federal research and regulatory programs now in place to address these risks.

This is the second of two OTA assessments on the subject of high-temperature superconductivity (HTS). As the title suggests, this study attempts to put HTS in perspective, both in terms of competing technologies (e.g., the more mature low-temperature superconductors), and in terms of the many technical and economic problems that must be overcome before HTS can be widely used.

This report is the final, summarizing report in a series of products from a broad assessment of space transportation technologies undertaken by OTA for the Senate Committee on Commerce, Science, and Transportation, and the House Committee on Science, Space, and Technology.

The House Committee on Government Operations, Subcommittee on Human Resources and Intergovernmental Relations asked the Office of Technology Assessment (OTA) to document the extent to which federally funded research on AIDS/HIV has contributed to advances in other fields including biomedical and behavior research, prevention, patient care, and health care financing. In response to this request OTA conducted a survey of distinguished biomedical and social scientists. This Staff Paper reports on the results of that survey.

For this report OTA compiled time-series data provided by the National Science Foundation (NSF) and the Federal mission agencies on proposals for competitively awarded research projects, and by the American Association for the Advancement of Science’s (AAAS) annual R&D budget series.7 These funding trends, presented below, suggest changes over the decade of the 1980s and raise some issues for future policy study.