Various biochemical effects of radiation have been studied in 10 patients given total body x-ray in total doses of 75 to 310 r (skin), in 5 patients given 20 to 36 mc. P{sup 32}, and in 5 project personnel accidentally exposed to excessive doses of external radiations. Similar studies have also been made of several hundred Plutonium Project personnel exposed in most instances to relatively small amounts of uranium, lead and other metals, and to chemicals and radioactive sources. These studies included the investigation of liver function, of white blood cell chemistry, and of various urinary constituents such as coproporphyrin, urorosein and other pigments, urobilinogen, ``corticosteroid-like`` substances, catalase, and uranium. Definitely excessive exposures resulted in various abnormalities in the above tests. With the exception of urinary uranium analysis none of them are specific in indicating overexposure to either radiation, metals, or chemicals. When interpreted in the light of the exposure and medical history, however, it is felt that they may aid in the clinical interpretation of relatively marked overexposure at least. In addition, they may afford further insight into the nature of radiation effects. The literature on the biochemical effects of radiation is reviewed briefly, and certain suggestions are offered …

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This memorandum discusses the roflanging of the corroded rear Van Stone flanges at the B Pile after cutting 3/8-inch off the rear gun barrel which should place the B Pile in a condition as good as, or better than that of the D or F Piles.

This report provides the monthly radiation monitoring sampling surveys for 1947.

This report contains a letter, written on July 25, 1947, concerning the sampling program at Columbia River. The author suggests reducing the sampling schedule. He states that chemical composition sampling should be reduced by one-fifth and radioactivity sampling be reduced by one-third. He suggests that only mid-channel samples are required for representative studies. He further states that weekly sampling should occur. By following these suggestions, the cost of the sampling program should be drastically reduced because the hours of manpower taken to sample the river, analyze the data, organize, and store information would be reduced.

Data acquired form the sampling of Yakima River water-t Tests is presented. The sampling took place on June 24, 1947. The samples were analyzed for ph value, alkalinity, chlorine, harness, NH(sub 3), NO(sub 3), biological oxygen demand, dissolved oxygen, and turbidity.

Data acquired from the sampling of Columbia River water July 24, 1947, is presented. The water was analyzed for temperature, hardness, turbidity, dissolved oxygen, chlorine, ph value, NO{sub 3}, NH{sub 3}, total solids, and alkalinity.

Data acquired form the sampling of Yakima River water July 24, 1947, is presented. The water was analyzed for hardness, turbidity, dissolved oxygen, ph value, alkalinity, chlorine, NH(sub 3), NO(sub 3), and total solids.

Data acquired from the sampling of Yakima River water on June 24, 1947, is presented. The water was analyzed for temperature, hardness, turbidity, dissolved oxygen, chlorine, alkalinity, NO(sub 3), NH(sub 3), and ph value.

On June 23, 1947, a hole was discovered in the earthen fill near the T Plant R-19 stairwell directly above the path followed by the underground waste lines from the canyon. Jetting of all canyon wastes to the 241 Buildings was stopped and the canyon process shut down. This report discusses repair and characterization procedures for the soils and waste line pipe.