A letter report issued by the Government Accountability Office with an abstract that begins "The Department of Defense (DOD) provides health care through its TRICARE program, which is managed by the TRICARE Management Activity (TMA). TRICARE offers three basic options. Beneficiaries who choose TRICARE Prime, an option that uses civilian provider networks, must enroll. TRICARE beneficiaries who do not enroll in this option may obtain care from nonnetwork providers under TRICARE Standard or from network providers under TRICARE Extra. The National Defense Authorization Act for Fiscal Year 2008 directed GAO to evaluate various aspects of beneficiaries' access to care under the TRICARE Standard and Extra options. This report examines (1) impediments to TRICARE Standard and Extra beneficiaries' access to civilian health care and mental health care providers and TMA's actions to address the impediments; (2) TMA's efforts to monitor access to civilian providers for TRICARE Standard and Extra beneficiaries; (3) how TMA informs network and nonnetwork civilian providers about TRICARE Standard and Extra; and (4) how TMA informs TRICARE Standard and Extra beneficiaries about their options. To address these objectives, GAO reviewed and analyzed TMA and TRICARE contractor data and documents. GAO also interviewed TMA officials, including those in its …

Testimony issued by the Government Accountability Office with an abstract that begins "The Department of the Interior oversees oil and gas activities on leased federal lands and waters. Revenue generated from federal oil and gas production is one of the largest nontax sources of federal government funds, accounting for about $9 billion in fiscal year 2009. Since the April 2010 explosion on board the Deepwater Horizon, Interior has been in the midst of restructuring the bureaus that oversee oil and gas development. Specifically, Interior's Bureau of Land Management (BLM) oversees onshore federal oil and gas activities; the Bureau of Ocean Energy Management, Regulation, and Enforcement (BOEMRE)--created in May 2010--oversees offshore oil and gas activities; and the newly established Office of Natural Resources Revenue (ONRR) is responsible for collecting royalties on oil and gas produced from both onshore and offshore federal leases. Prior to BOEMRE, the Minerals Management Service's (MMS) Offshore Energy and Minerals Management Office oversaw offshore oil and gas activities and revenue collection. In 2011, GAO identified Interior's management of oil and gas resources as a high risk issue. GAO's work in this area identified challenges in five areas: (1) reorganization, (2) balancing responsibilities, (3) human capital, (4) revenue …

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FACET is a new facility under construction at the SLAC National Accelerator Laboratory. The FACET beam line is designed to provide 23 GeV tightly focused and compressed electron and positron bunches for beam driven plasma wakefield acceleration research and other experiments. Achieving optimal beam parameters for various experimental conditions requires the optics capability for tuning in a sufficiently wide range. This will be achieved by using optics tuning systems (knobs). Design of such systems for FACET is discussed.

The SUPER-B detector solenoid has a strong 1.5 T field in the Interaction Region (IR) area, and its tails extend over the range of several meters. The main effect of the solenoid field is coupling of the horizontal and vertical betatron motion which must be corrected in order to preserve the small design beam size at the Interaction Point. The additional effects are orbit and dispersion caused by the angle between the solenoid and beam trajectories. The proposed correction system provides local compensation of the solenoid effects independently for each side of the IR. It includes 'bucking' solenoids to remove the solenoid field tails and a set of skew quadrupoles, dipole correctors and anti-solenoids to cancel linear perturbations to the optics. Details of the correction system are presented.

We investigate the nature of the mass-metallicity (M-Z) relation for long gamma-ray burst (LGRB) host galaxies. Recent studies suggest that the M-Z relation for local LGRB host galaxies may be systematically offset towards lower metallicities relative to the M-Z relation defined by the general star forming galaxy (SDSS) population. The nature of this offset is consistent with suggestions that low metallicity environments may be required to produce high mass progenitors, although the detection of several GRBs in high-mass, high-metallicity galaxies challenges the notion of a strict metallicity cut-off for host galaxies that are capable of producing GRBs. We show that the nature of this reported offset may be explained by a recently proposed anti-correlation between the star formation rate (SFR) and the metallicity of star forming galaxies. If low metallicity galaxies produce more stars than their equally massive, high-metallicity counterparts, then transient events that closely trace the SFR in a galaxy would be more likely to be found in these low metallicity, low mass galaxies. Therefore, the offset between the GRB and SDSS defined M-Z relations may be the result of the different methods used to select their respective galaxy populations, with GRBs being biased towards low metallicity, high SFR, …

In cyanobacteria CO2 fixation is localized in a special proteinaceous organelle, the carboxysome. The CO2 fixation enzymes are encapsulated by a selectively permeable protein shell. By structurally and functionally characterizing subunits of the carboxysome shell and the encapsulated proteins, we hope to understand what regulates the shape, assembly and permeability of the shell, as well as the targeting mechanism and organization of the encapsulated proteins. This knowledge will be used to enhance CO2 fixation in both cyanobacteria and plants through synthetic biology. The same strategy can also serve as a template for the production of modular synthetic bacterial organelles. Our research is conducted using a variety of techniques such as genomic sequencing and analysis, transcriptional regulation, DNA synthesis, synthetic biology, protein crystallization, Small Angle X-ray Scattering (SAXS), protein-protein interaction assays and phenotypic characterization using various types of cellular imaging, e.g. fluorescence microscopy, Transmission Electron Microscopy (TEM), and Soft X-ray Tomography (SXT).

The NLC Test Accelerator (NLCTA) at SLAC is currently configured for a proof-of-principle echo-enabled harmonic generation (EEHG) experiment using an 120 MeV beam. During commissioning, unexpected coherent optical undulator radiation (CUR) and coherent optical transition radiation (COTR) was observed when beam is accelerated off-crest and compressed after the chicanes. The CUR and COTR is likely due to a microbunching instability where the initial small ripples in cathode drive laser is compressed and amplified. In this paper we present the observation and characterization of the CUR, COTR and microbunching instability at NLCTA.

Rotation of the plane of polarization of reflected light (Kerr effect) is a direct manifestation of broken time reversal symmetry and is generally associated with the appearance of a ferromagnetic moment. Here I identify magnetic structures that may arise within the unit cell of cuprate superconductors that generate polarization rotation despite the absence of a net moment. For these magnetic symmetries the Kerr effect is mediated by magnetoelectric coupling, which can arise when antiferromagnetic order breaks inversion symmetry. The structures identifed are candidates for a time-reversal breaking phase in the pseudogap regime of the cuprates.

To date the vast majority of bacterial and archaeal genomes sequenced are of rather limited phylogenetic diversity as they were chosen based on their physiology and/ or medical importance. The Genomic Encyclopedia of Bacteria and Archaea (GEBA) project (Wu et al. 2009) is aimed at systematically filling the gaps of the tree of life with phylogenetically diverse reference genomes. However more than 99 percent of microorganisms elude current culturing attempts, severely limiting the ability to recover complete or even partial genomes of these largely mysterious species. These limitations gave rise to the GEBA uncultured project. Here we propose to use single cell genomics to massively expand the Genomic Encyclopedia of Bacteria and Archaea by targeting 80 single cell representatives of uncultured candidate phyla which have no or very few cultured representatives. Generating these reference genomes of uncultured microbes will dramatically increase the discovery rate of novel protein families and biological functions, shed light on the numerous underrepresented phyla that likely play important roles in the environment, and will assist in improving the reconstruction of the evolutionary history of Bacteria and Archaea. Moreover, these data will improve our ability to interpret metagenomics sequence data from diverse environments, which will be of …

De novo assembly of the transcriptome is crucial for functional genomics studies in bioenergy research, since many of the organisms lack high quality reference genomes. In a previous study we successfully de novo assembled simple eukaryote transcriptomes exclusively from short Illumina RNA-Seq reads [1]. However, extensive alternative splicing, present in most of the higher eukaryotes, poses a significant challenge for current short read assembly processes. Furthermore, the size of next-generation datasets, often large for plant genomes, presents an informatics challenge. To tackle these challenges we present a combined experimental and informatics strategy for de novo assembly in higher eukaryotes. Using maize as a test case, preliminary results suggest our approach can resolve transcript variants and improve gene annotations.

Testimony issued by the Government Accountability Office with an abstract that begins "Identity theft is a serious and growing problem in the United States. Taxpayers are harmed when identity thieves file fraudulent tax documents using stolen names and Social Security numbers. In 2010 alone, the Internal Revenue Service (IRS) identified over 245,000 identity theft incidents that affected the tax system. The hundreds of thousands of taxpayers with tax problems caused by identity theft represent a small percentage of the expected 140 million individual returns filed, but for those affected, the problems can be quite serious. GAO was asked to describe, among other things, (1) when IRS detects identity theft based refund and employment fraud, (2) the steps IRS has taken to resolve, detect, and prevent innocent taxpayers' identity theft related problems, and (3) constraints that hinder IRS's ability to address these issues. GAO's testimony is based on its previous work on identity theft. GAO updated its analysis by examining data on identity theft cases and interviewing IRS officials."

Fully understanding the genetic potential of a microbial community requires functional annotation of all the genes it encodes. The recently developed deep metagenome sequencing approach has enabled rapid identification of millions of genes from a complex microbial community without cultivation. Current homology-based gene annotation fails to detect distantly-related or structural homologs. Furthermore, homology searches with millions of genes are very computational intensive. To overcome these limitations, we developed rhModeller, a homology-independent software pipeline to efficiently annotate genes from metagenomic sequencing projects. Using cellulases and carbonic anhydrases as two independent test cases, we demonstrated that rhModeller is much faster than HMMER but with comparable accuracy, at 94.5percent and 99.9percent accuracy, respectively. More importantly, rhModeller has the ability to detect novel proteins that do not share significant homology to any known protein families. As {approx}50percent of the 2 million genes derived from the cow rumen metagenome failed to be annotated based on sequence homology, we tested whether rhModeller could be used to annotate these genes. Preliminary results suggest that rhModeller is robust in the presence of missense and frameshift mutations, two common errors in metagenomic genes. Applying the pipeline to the cow rumen genes identified 4,990 novel cellulases candidates and 8,196 novel …

The geometry of storage ring collider interaction regions present an impedance to beam fields resulting in the generation of additional electromagnetic fields (higher order modes or wake fields) which affect the beam energy and trajectory. These affects are computed for the Super B interaction region by evaluating longitudinal loss factors and averaged transverse kicks for short range wake fields. Results indicate at least a factor of 2 lower wake field power generation in comparison with the interaction region geometry of the PEP-II B-factory collider. Wake field reduction is a consderation in the Super B design. Transverse kicks are consistent with an attractive potential from the crotch nearest the beam trajectory. The longitudinal loss factor scales as the -2.5 power of the bunch length. A factor of 60 loss factor reduction is possible with crotch geometry based on an intersecting tubes model.

SLAC is investigating long-range options for building a high performance light source machine while reusing the existing linac and PEP-II tunnels. One previously studied option is the PEP-X low emittance storage ring. The alternative option is based on a superconducting Energy Recovery Linac (ERL) and the PEP-X design. The ERL advantages are the low beam emittance, short bunch length and small energy spread leading to better qualities of the X-ray beams. Two ERL configurations differed by the location of the linac have been studied. Details of the lattice design and the results of beam transport simulations with the coherent synchrotron radiation effects are presented.

ECHO-7 is a proof-of-principle echo-enabled harmonic generation (EEHG) FEL experiment in the Next Linear Collider Test Accelerator (NLCTA) at SLAC. The experiment is intended to test the EEHG principle at low electron beam energy, 120 MeV, and determine the sensitivities and limitations to understand the expected performance at the higher energy scales and harmonic numbers required for x-ray FELs. In this paper we present the experimental results from the commissioning run of the completed experimental setup which started in April 2010.

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This report is on Border Security: CRS Experts.

This report mainly focuses on China-U.S. Trade Issues. China-U.S. ties have been substantially expanded over the past three decades. U.S imports from China have risen much more rapidly than U.S exports to China.

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The Community Oriented Policing Services (COPS) program was created by Title I of the Violent Crime Control and Law Enforcement Act of 1994 (P.L. 103-322). The mission of the COPS program is to advance community policing in all jurisdictions across the United States. Legislation introduced in the 111th Congress would reauthorize the COPS program through FY2014 and reestablish COPS as a multi-grant program. This report provides an overview and analysis of issues Congress might choose to consider when taking up legislation to reauthorize the COPS program.

This report discusses the implications from the U.S.-South Korean Free Trade Agreement on aspects of U.S. business, particularly the auto industry.