Computer graphic representation of the antigen-binding sites of two Bence-Jones proteins (antibody light chain diners), Loc (left) and Mcg (right). The spheres represent individual amino acids. Each binding site is composed of two variable domains and each domain consists of framework segments and the hyper-variable segments which confer the specificity to the antibody molecule.

This report presents a diagnostic automation that can be used to investigate classes of systems without feedback loops. This report shows the input needed for the automation, the algorithm used, and the PROLOG program for the simulation.

A central solar-heating plant with seasonal heat storage in a deep underground aquifer is designed by means of a solar-seasonal-storage-system simulation code based on the Solar Energy Research Institute (SERI) code for Solar Annual Storage Simulation (SASS). This Solar Seasonal Storage Plant is designed to supply close to 100% of the annual heating and domestic-hot-water (DHW) load of a hypothetical new community, the Fox River Valley Project, for a location in Madison, Wisconsin. Some analyses are also carried out for Boston, Massachusetts and Copenhagen, Denmark, as an indication of weather and insolation effects. Analyses are conducted for five different types of solar collectors, and for an alternate system utilizing seasonal storage in a large water tank. Predicted seasonal performance and system and storage costs are calculated. To provide some validation of the SASS results, a simulation of the solar system with seasonal storage in a large water tank is also carried out with a modified version of the Swedish Solar Seasonal Storage Code MINSUN.

The primary-coolant flow paths of a reactor system are usually subject to close scrutiny in a design review to identify potential flow-induced vibration sources. However, secondary-flow paths through narrow gaps in component supports, which parallel the primary-flow path, occasionally are the excitation source for significant vibrations even though the secondary-flow rates are orders of magnitude smaller than the primary-flow rate. These so-called leakage flow problems are reviewed here to identify design features and excitation sources that should be avoided. Also, design rules of thumb are formulated that can be employed to guide a design, but quantitative prediction of component response is found to require scale-model testing.

The goal of this study was to develop an iron-based alloy, similar to Type 316 stainless steel in mechanical and corrosion properties but with a reduced chromium content or, ideally, no chromium. A total of twenty-six 225-g ingots and ten 2.5 to 12 kg ingots of various compositions in the Fe-Si-Mn-Ni-C system were prepared. All ingots contained from 5 to 11 w/o silicon and drew their corrosion resistance primarily from this component. The composition ranges of the remaining major alloying elements were (in w/o) 0-24 Mn, 0-35 Ni, and 0.08 to 0.95 C. Most of the alloys were reduced to sheet, demonstrating the hot fabricability of these high-silicon alloys. The mechanical and corrosion properties of these alloys are attractive. Tensile tests showed yield strengths of 303 to 379 Mpa (44 to 55 ksi), ultimate tensile strengths of 731 to 882 MPa (106 to 128 ksi), and elongations of 34 to 77%. Air oxidation rates were lower than those of 300-series stainless steels at 1000 C. Salt water corrosion rates for these alloys fall between those of stainless steels and plain carbon steels and are 5 to 10 times lower than the rates for plain carbon steels.