Innes, Zemen, Frenkel, Borner and Wright (1962) described an outbreak of encephalitozoönosis of the central nervous system in mice, a summary of which is given below for an understanding of why this appendix may be of interest. When the paper was presented for publication, the editors of the journal decided to omit the history of our mouse colony. In our opinion, to understand (a) how this infection may have arisen and (b) may have spread, and still exist in some colonies, it is of prime importance to know the history of this strain of mice used by us (and others). It also has lessons on the establishment and maintenance of so-called "disease-free" or "specific pathogen-free"* colonies of laboratory animals in general. Information on the history of the mice has been culled from Col. H. Yager, VC, Director of the Division of Veterinary Medicine, Walter Reed Army Institute of Medical Research, Washington, D. C., and from Drs, Clara Lynch and John B. Nelson, Rockefeller Institute, New York.

The purpose of this paper is to present tables of the perturbed wave functions which have been recently obtained in a calculation of the quadruple antishielding factors γ∞ for the Mn+2, Fe+3, Ga+3, and Ag+ ions. The wave functions v'1(nℓ-ℓ) which are tabulated represent the effect of the perturbation due to a nuclear quadruple moment Q on the wave functions of the outermost electrons of the ion core.

The enzymolysis by α-chymotrypsin of the substrates, N-acetyl-L-tryptophane ethyl ester and N-acetyl-L-tyrosine ethyl ester, was followed by means of fluorescence whose intensity increased fourfold and threefold per mole respectively as substrate was transformed into amino acid. The assay by fluorescence was several orders of magnitude more sensitive than the assay by differential absorption spectra of these substances and was in agreement with it in those concentration regions where both methods overlap. To maintain linearity between concentration and fluorescence intensity, the concentration of substrate should be no greater than 10-4 M/1. In such solutions the rate of esterolysis could be followed with the enzyme at 10-11 M/1.

An isochronal differential-type microcalorimeter has been designed and constructed. As a result of its simple design it is very easy to handle the samples and assemble the calorimeter. Important to the operation of the calorimeter is a program, also working on the differential principle, that provides linear temperature rise of the samples. This calorimeter is used to measure very small energy releases such as those found in precipitation, stored energy, etc. It is demonstrated that the calorimeter is easily capable of measuring 0.0005 cal with a probable error of the order of 1% to 2%.

Cowley's measurements of the short-range order parameters, αi, in Cu3Au at T=405°C have been re-evaluated taking into account the effects of thermal vibrations and static displacements due to differing atomic sizes. The separate corrections for the thermal vibrations and the first-neighbor atomic size factor are found to be quite large, demonstrating their importance in the usual experiments. When combined, the corrections in this case largely cancel, and only the values of α1 and α3 are appreciably changed. The corrected values are: α1= -.113, α2= +.185, α3= -.009, α4= +.082, α5= -.058.

The role of the marrow as a site for antibody formation has been considered for many years. In 1912 Ludke reported the appearance of antibody in cultures of marrow cells obtained from previously immunized rabbits. Specific agglutinins for killed typhoid bacilli and lysins for ox red cells and sheep red cells were detected in the culture media 2 to 5 days later. However, the cultured cells failed to produce antibody when these antigens were added to the media. Similar findings by Reiter, Przygode, and Schilf appeared in the early literature with regard to the appearance of antibodies to various antigens in tissue cultures of bone marrow from immunized animals, along with failure to elicit antibody formation by addition of antigen to the culture resulted from the addition of excess amounts of antigen, so that if antibody synthesis occurred, the excess antigen combined with antibody and significant amounts of free antibody could not be detected in the culture media. Thorbecke and Keuning observed an increase in antibody in culture fluids when bone marrow fragments from rabbits immunized to paratyphoid B vaccine were cultured in roller tubes.

A kinetic study of the exchange of normal and radioactive bromine in graphite-bromine lamellar compounds has been made at temperatures of 30° to 50°C. Natural and synthetic graphite powders were investigated. Two alternative mechanisms for the exchange, volume diffusion and surface exchange, were considered. The data were in better agreement with the diffusion mechanism. Diffusion coefficients of 10 -9 to 10 -8 cm2/sec and an activation energy of 11 to 14 kcal/mole were calculated for the natural graphite powders. The diffusion coefficients increased with increasing bromine content. Reversibly absorbed bromine exchanged more rapidly than irreversibly absorbed bromine.

The cobalt and molybdenum positions had been derived from a three-dimensional Patterson function based on complete data out to λ-1 sin θMo≈ 1. From the separation of the separation of the Mo atoms it was thought that the structure contained free, unlinked MoO4 -2 ions, and this, together with the observed density and analyses for Co and Mo, suggested that the composition was probably Co2(MoO4)3. The paucity of structural information on complex oxide systems and the interesting properties, both structural and physical, of such systems prompted the present, detailed refinement of the structure. The result is more complicated and more interesting than had been anticipated: from the analysis of the X-ray data the compound is found to be NaCo2.31(MoO4)3, and this composition is consistent with chemical analyses. The structure shows several interesting features, including the partial occupancy of cobalt atoms in two independent CoO6 octahedral sites. In one arrangement of CoO6 octahedra there is the not too common face sharing to form infinite columns; in the other arrangement a zig-zag sheet, as far as we know differing from anything thus far reported, is formed by the sharing of edges and corners.

The analysis of closed circuit systems in which spontaneous steady-state electric currents appear can be carried out with the use of the function [function not transcribed]. The analysis indicates that any open circuit system of the form. Phase 1, barrier 1, phase 2, ......, phase b, barrier b, phase 1' is a chemical source of electromotive force when the phase 1 and 1' are identical, when the system contains two or more barriers whose sets of ionic transport members are different, and when the system is composed of two or more phases whose chemical properties are different. A general expression for the electromotive force of model systems composed of homogeneous phases and biological membranes in linear array can be written as [expression not transcribed] in which the indicated summations are to be performed for all barriers and for all ions to which each barrier is permeable.

None

During the 18-year history of Hanford operations, a high degree of safety has been provided at reasonable cost by the storage of high-activity liquid wastes in underground tanks, by the percolation of low-activity liquid wastes (principally water) through the soil to the ground water, and by the adsorption or filtration of radioactive materials from gaseous effluents prior to their discharge to the atmosphere. Studies of the Hanford area indicate that current practices could be continued almost indefinitely without jeopardizing environmental safety, provided the stored liquid wastes are periodically transferred to new tanks before the existing ones fail. In 1960, a Fission Product Recovery Program was prepared outlining a plan to meet the Atomic Energy Commission`s needs for isolated fission products. Emphasis was placed on developing processes for isolating selected fission products and on providing interim production capability for recovering the fission products of immediate interest. In 1961, development efforts were channeled almost exclusively toward meeting the immediate needs of the Commission for separated strontium-90 and cesium-137. During this time, it became increasingly evident that substantial economies could be realized, both in immediate development and subsequent operating efforts, if the separate fission product recovery and waste management programs were merged. The …

A system of six codes is described that permits the solution of a broad class of problems encountered in the study of neutron thermalization, average cross sections, and spectral models. These programs are all compatible with use on MONITOR for the IBM 7090. The Fortran listings are given. (auth)

A transfer function for d-c operational amplifiers with generalized input and feed-back networks is derived by application of network theory. This transfer function, more general than others in common use, applies to three and four-terminal networks. It contains, as a special case, the well-known transfer function for d-c operational amplifiers with two-terminal networks. Examples are given. (auth)

The basic heat transfer and flow equations applicable to studies of flow oscillations in NERVA engines are first linearized, then expressed as difference-differential approximations, and finally written in a form suitable for analog computer solution. Block diagrams are presented which illustrate on analog procedure for solving the linearized, difference-differential equations.

Document issued by the Office of the Attorney General of Texas in Austin, Texas, providing an interpretation of Texas law. It provides the opinion of the Texas Attorney General, Waggoner Carr, regarding a legal question submitted for clarification: Construction of proposed rider to the General Appropriations Bill.