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Molecular signatures in the progression of COVID-19 severity
Authors of the article discuss that to uncover genes and pathways involved in the differential clinical manifestations of COVID-19 they developed a novel gene co-expression network-based pipeline that uses gene expression obtained from different SARS-CoV-2 infected human tissues. Their study shines a new light on genes and their networks (modules) that drive the progression of COVID-19 from moderate to extremely severe condition, which could aid development of new therapeutics to combat COVID-19.
Date:
December 21, 2022
Creator:
De, Ronika & Azad, Rajeev K.
Object Type:
Article
System:
The UNT Digital Library
A gene network-driven approach to infer novel pathogenicity-associated genes: application to Pseudomonas aeruginosa PAO1
Article describes how within the genome of a pathogen is the information regarding factors responsible for its pathogenicity. the authors of the article developed a novel pipeline that uses standard protocol in combination with gene co-expression network of a pathogen constructed using publicly available RNA-Seq data sets.
Date:
November 3, 2023
Creator:
De, Ronika; Whiteley, Marvin & Aza, Rajeev K.
Object Type:
Article
System:
The UNT Digital Library
Deep Minima in the Triply Differential Cross Section for Ionization of Atomic Hydrogen by Electron and Positron Impact
Article investigating ionization of atomic hydrogen by electron- and positron-impact. This article belongs to the Special Issue: Interactions of Positrons with Matter and Radiation.
Date:
May 29, 2020
Creator:
DeMars, C. M.; Ward, S. J.; Colgan, J.; Amami, S. & Madison, D. H.
Object Type:
Article
System:
The UNT Digital Library
Model checking via testing for direct effects in Mendelian Randomization and transcriptome-wide association studies
This article proposes a new and general goodness-of-fit (GOF) test, called TEDE (TEsting Direct Effects), applicable to both correlated and independent SNPs/IVs as commonly used in transcriptome-wide association studies (TWAS) and Mendelian randomization (MR) respectively.
Date:
August 2, 2021
Creator:
Deng, Yangqing & Pan, Wei
Object Type:
Article
System:
The UNT Digital Library
Activation of an S6 Kinase From Human Placenta by Autophosphorylation
Article describing a novel S6 kinase isolated from human placenta which autoactivates through autophosphorylation in vitro. The data supports the hypothesis that this previously uncharacterized S6 kinase belongs to a unique family of protein kinases which utilize autophosphorylation as part of their in vivo activation mechanism.
Date:
September 15, 1993
Creator:
Dennis, Patrick B. & Masaracchia, Ruthann A.
Object Type:
Article
System:
The UNT Digital Library
Peptide signaling molecules CLE5 and CLE6 affect Arabidopsis leaf shape downstream of leaf patterning transcription factors and auxin
Article describes a role in Arabidopsis leaf development for two members of the CLAVATA3/ESR‐RELATED peptide family, CLE5 and CLE6, which lie adjacent to each other on chromosome 2.
Date:
December 20, 2018
Creator:
DiGennaro, Peter; Grienenberger, Etienne; Dao, Thai Q.; Jun, Ji Hyung & Fletcher, Jennifer C.
Object Type:
Article
System:
The UNT Digital Library
Duals of Tirilman spaces have unique subsymmetric basic sequences
Article describes how the Tirilman spaces were introduced by Casazza and Shura as variations of the spaces constructed by Tzafriri. We prove that all subsymmetric basic sequences in the dual space are equivalent to its canonical subsymmetic but not symmetric basis.
Date:
September 5, 2023
Creator:
Dilworth, Steven J.; Kutzarova, Denka; Sari, Bünyamin & Stankov, Svetozar
Object Type:
Article
System:
The UNT Digital Library
Function of Conserved Residues of Human Glutathione Synthetase: Implications for the ATP-Grasp Enzymes
Article examining the mechanism of Glutathione synthetase, an enzyme that belongs to the glutathione synthetase ATP-binding domain-like superfamily. A variety of structural alignment methods were applied and four highly conserved residues of human glutathione synthetase (Glu-144, Asn-146, Lys-305, and Lys-364) were identified in the binding site. The function of these was studied by experimental and computational site-directed mutagenesis.
Date:
May 21, 2004
Creator:
Dinescu, Adriana; Cundari, Thomas R., 1964-; Bhansali, Vikas S.; Luo, Jia-Li & Anderson, Mary E.
Object Type:
Article
System:
The UNT Digital Library
Brain Inflammation, Blood Brain Barrier dysfunction and Neuronal Synaptophysin Decrease after Inhalation Exposure to Titanium Dioxide Nano-aerosol in Aging Rats
This article focuses on the consequences of TiO₂ distribution on the central nervous system and particularly on the blood-brain barrier functions.
Date:
June 15, 2017
Creator:
Disdier, Clémence; Chalansonnet, Monique; Gagnaire, François; Gaté, Laurent; Cosnier, Frédéric; Devoy, Jérôme et al.
Object Type:
Article
System:
The UNT Digital Library
Gemini Near Infrared Spectrograph–Distant Quasar Survey: Prescriptions for Calibrating UV-based Estimates of Supermassive Black Hole Masses in High-redshift Quasars
Article describes how the most reliable single-epoch supermassive black hole mass (MBH) estimates in quasars are obtained by using the velocity widths of low-ionization emission lines, typically the Hβλ4861 line. The authors find that utilizing both emission lines, where available, reduces the scatter of UV-based MBH estimates by ∼15% when compared to previous studies.
Date:
June 13, 2023
Creator:
Dix, Cooper; Matthews, Brandon; Shemmer, Ohad; Brotherton, Michael S.; Myers, Adam D.; Andruchow, I. et al.
Object Type:
Article
System:
The UNT Digital Library
Prescriptions for Correcting Ultraviolet-based Redshifts for Luminous Quasars at High Redshift
This article presents near-infrared spectroscopy of 18 luminous quasars at 2.15 < z < 3.70 that allows the authors to obtain reliable systemic redshifts for these sources.
Date:
April 8, 2020
Creator:
Dix, Cooper; Shemmer, Ohad; Brotherton, Michael S.; Green, Richard F.; Mason, Michelle & Myers, Adam D.
Object Type:
Article
System:
The UNT Digital Library
Lignin biosynthesis: old roads revisited and new roads explored
Article presents several hypothetical models to illustrate information about lignin and the lignification process in plants.
Date:
December 4, 2019
Creator:
Dixon, R. A. & Barros, Jaime
Object Type:
Article
System:
The UNT Digital Library
Proanthocyanidin Biosynthesis—a Matter of Protection
Article discussing key questions and opportunities in the field of Proanthocyanidins (PA) biosynthesis.
Date:
August 18, 2020
Creator:
Dixon, R. A. & Sarnala, Sai
Object Type:
Article
System:
The UNT Digital Library
VvLAR1 and VvLAR2 Are Bifunctional Enzymes for Proanthocyanidin Biosynthesis in Grapevine
This article shows that both Cys-EC and 4β-(S-cysteinyl)-catechin (Cys-C) are present in grapevine. The data from this study advance knowledge of PA building blocks and LAR function and provide targets for grapevine breeding to alter PA composition.
Date:
May 15, 2019
Creator:
Dixon, R. A.; Jun, Ji Hyung; Yu, Keji & Duan, Changqing
Object Type:
Article
System:
The UNT Digital Library
The Tetracentron genome provides insight into the early evolution of eudicots and the formation of vessel elements
Article reporting a chromosome-scale assembly of the T. sinense genome.
Date:
December 2, 2020
Creator:
Dixon, R. A.; Liu, Ping-Li; Zhang, Xi; Mao, Jian-Feng; Hong, Yan-Ming; Zhang, Ren-Gang et al.
Object Type:
Article
System:
The UNT Digital Library
Phosphorus deprivation affects composition and spatial distribution of membrane lipids in legume nodules
Article assessing membrane lipids in M. truncatula tissues using electrospray ionization–mass spectrometry. The results suggest that specific PC species may be differentially important in diverse nodule zones and cell types, and that membrane lipid remodeling during P stress is not uniform across the nodule.
Date:
January 13, 2021
Creator:
Dokwal, Dhiraj; Romsdahl, Trevor B.; Kunz, Daniel A.; Alonso, Ana Paula & Dickstein, Rebecca
Object Type:
Article
System:
The UNT Digital Library
Topological View of Flows Inside the BOLD Spontaneous Activity of the Human Brain
Article describes study which found that persistent, recurring blood oxygen level dependent (BOLD) signals in triangulated rs-fMRI videoframes display previously undetected topological findings, i.e., vortex structures that cover brain activated regions.
Date:
April 22, 2020
Creator:
Don, Arjuna P. H.; Peters, James F.; Ramanna, Sheela & Tozzi, Arturo
Object Type:
Article
System:
The UNT Digital Library
Genome Sequences of Five Streptomyces Bacteriophages Forming Cluster BG
This article discusses the isolation of five novel phages, which were used to established the cluster BF, using Streptomyces griseus subsp. griseus strain ATcC 10137 as the host.
Date:
July 13, 2017
Creator:
Donegan-Quick, Richard; Gibbs, Zane A.; Amaku, Patricia O.; Bernal, Joshua T.; Boyd, Dana A. M.; Burr, Angela R. et al.
Object Type:
Article
System:
The UNT Digital Library
Arabidopsis thaliana EARLY RESPONSIVE TO DEHYDRATION 7 Localizes to Lipid Droplets via Its Senescence Domain
This article includes a proteomics analysis of Lipid Droplets (LDs) isolated from drought-stressed Arabidopsis leaves and identifying EARLY RESPONSIVE TO DEHYDRATION 7 (ERD7) as a putative LD protein. Observations provide new insight to ERD7 and the SD-containing family of proteins in plants and suggest that ERD7 may be involved in functional aspects of plant stress response that also include localization to the LD surface.
Date:
April 14, 2021
Creator:
Doner, Nathan M.; Seay, Damien C.; Mehling, Marina; Sun, Siqi; Gidda, Satinder K.; Schmitt, Kerstin et al.
Object Type:
Article
System:
The UNT Digital Library
The Arabidopsis PAD4 Lipase-Like Domain Is Sufficient for Resistance to Green Peach Aphid
Article exploring PAD4 functions in plant defense by expressing the N-terminal PAD4 lipase-like domain (PAD4ᴸᴸᴰ) without its C-terminal EDS1-PAD4 (EP) domain. The authors show that transgenic expression of PAD4ᴸᴸᴰ in Arabidopsis is sufficient for limiting GPA infestation but not for conferring basal and effector-triggered pathogen immunity. This suggests that the C-terminal PAD4 EP domain is necessary for EDS1-dependent immune functions but is dispensable for aphid resistance. Moreover, PAD4ᴸᴸᴰ is not sufficient to interact with EDS1, indicating the PAD4-EP domain is required for stable heterodimerization. These data provide molecular evidence that PAD4 has domain-specific functions.
Date:
December 27, 2019
Creator:
Dongus, Joram A.; Bhandari, Deepak D.; Patel, Monika; Archer, Lani; Dijkgraaf, Lucas; Shah, Jyoti et al.
Object Type:
Article
System:
The UNT Digital Library
Cavity surface residues of PAD4 and SAG101 contribute to EDS1 dimer signaling specificity in plant immunity
Article investigating whether the EPDs of PAD4 and SAG101 contribute to EDS1 dimer functions.
Date:
October 27, 2021
Creator:
Dongus, Joram A.; Bhandari, Deepak D.; Penner, Eva; Lapin, Dmitry; Stolze, Sara C.; Harzen, Anne et al.
Object Type:
Article
System:
The UNT Digital Library
A globally synthesized and flagged bee occurrence dataset and cleaning workflow
Article describes how species occurrence data is foundational for research, conservation, and science communication, but the limited availability and accessibility of reliable data represents a major obstacle, particularly for insects, which face mounting pressures. The authors harmonized species names, country names, and collection dates and, we added record-level flags for a series of potential quality issues.
Date:
November 2, 2023
Creator:
Dorey, James B.; Fischer, Erica E.; Chesshire, Paige R.; Nava-Bolaños, Angela; O'Reilly, Robert L.; Bossert, Silas et al.
Object Type:
Article
System:
The UNT Digital Library
Elucidating the role of negative parenting in the genetic v. environmental influences on adult psychopathic traits
Article states that though adult psychopathic traits emerge from both genetic and environmental risk, no studies have examined etiologic associations between adult psychopathic traits and experiences of parenting in childhood, or the extent to which parenting practices may impact the heritability of adult psychopathic traits using a genetically-informed design. Utilizing a genetically-informed design, the authors found that both genetic and non-shared environmental factors contribute to the emergence of psychopathic traits.
Date:
August 12, 2021
Creator:
Dotterer, Hailey L.; Vazquez, Alexandra Y.; Hyde, Luke W.; Neumann, Craig S.; Santtila, Pekka; Pezzoli, Patrizia et al.
Object Type:
Article
System:
The UNT Digital Library
Engineered nonlinear materials using gold nanoantenna array
This article describes the use of a gold nanoantenna array to enhance both the nonlinear refractive index and two-photon absorption (2PA) of the organic dye 4,4'-bis(diphenylamino)stilbene (BDPAS), which is known as a dye with relatively large 2PA.
Date:
August 21, 2017
Creator:
Drachev, Vladimir P.; Kildishev, Alexander V.; Borneman, Joshua D.; Chen, Kuo-Ping; Shalaev, Vladimir; Yamnitskiy, Konstantin et al.
Object Type:
Article
System:
The UNT Digital Library