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Preferential Solvation Study of the Synthesized Aldose Reductase Inhibitor (SE415) in the {PEG 400 (1) + Water (2)} Cosolvent Mixture and GastroPlus-Based Prediction (open access)

Preferential Solvation Study of the Synthesized Aldose Reductase Inhibitor (SE415) in the {PEG 400 (1) + Water (2)} Cosolvent Mixture and GastroPlus-Based Prediction

Article is a study highlighting the mechanistic understanding of the dissolution process of SE415 by biocompatible PEG 400 in the (PEG 400 + water) cosolvent mixture using HSPs, Kirkwood–Buff integrals, and thermodynamic functional parameters for solubility.
Date: October 15, 2021
Creator: Hussain, Afzal; Altamimi, Mohammad A.; Afzal, Obaid; Altamimi, Abdulmalik S. A.; Ali, Abuzer; Ali, Amena et al.
Object Type: Article
System: The UNT Digital Library
Preferential Solvation Study of the Synthesized Aldose Reductase Inhibitor (SE415) in the {PEG 400 (1) + Water (2)} Cosolvent Mixture and GastroPlus-Based Prediction (open access)

Preferential Solvation Study of the Synthesized Aldose Reductase Inhibitor (SE415) in the {PEG 400 (1) + Water (2)} Cosolvent Mixture and GastroPlus-Based Prediction

This article presents evidence that the binary cosolvent system can be a promising approach for enhanced oral absorption in controlling diabetes mellitus (DM) and associated complications in humans.
Date: January 2, 2022
Creator: Hussain, Afzal; Altamimi, Mohammad A.; Afzal, Obaid; Altamimi, Abdulmalik S. A.; Ali, Abuzer; Ali, Amena et al.
Object Type: Article
System: The UNT Digital Library
Identification of Pueraria spp. through DNA barcoding and comparative transcriptomics (open access)

Identification of Pueraria spp. through DNA barcoding and comparative transcriptomics

This article presents research where various kudzu accessions were analyzed through barcoding and comparative transcriptomics, generating tools for identification and molecular pathway analysis.
Date: January 3, 2022
Creator: Adolfo, Laci M.; Rao, Xiaolan & Dixon, R. A.
Object Type: Article
System: The UNT Digital Library
Instructional Models for Course-Based Research Experience (CRE) Teaching (open access)

Instructional Models for Course-Based Research Experience (CRE) Teaching

This article presents a study that was done over a period of 3 years to explicate the instructional processes involved in teaching an undergraduate course-based research experience (CRE). The study presented here delineated a set of specific instructional practices used by active CRE instructors and modeled the relations between the use of these practices and specified outcomes. The resultant educational models should provide clarification of the ways in which the aims of CRE can be effectively achieved by instructors.
Date: January 3, 2022
Creator: Hanauer, David I.; Graham, Mark J.; Arnold, Rachel J.; Ayuk, Mary A.; Balish, Mitchell F.; Beyer, Andrea R. et al.
Object Type: Article
System: The UNT Digital Library
The metabolic cost of turning right side up in the Mediterranean spur-thighed tortoise (Testudo graeca) (open access)

The metabolic cost of turning right side up in the Mediterranean spur-thighed tortoise (Testudo graeca)

Article examining the the metabolic cost of self-righting in the terrestrial Mediterranean spur-thighed tortoise using respirometry and kinematic video analysis and comparing this to the metabolic cost of locomotion at a moderate, easily sustainable speed. The results found that self-righting is, relatively, metabolically expensive and costs around two times the mass-specific power required to walk.
Date: January 10, 2022
Creator: Ewart, Heather E.; Tickle, Peter G.; Sellers, William I.; Lambertz, Markus; Crossley, Dane A., II & Codd, Jonathan R.
Object Type: Article
System: The UNT Digital Library
Larval Development in Tropical Gar (Atractosteus tropicus) Is Dependent on the Embryonic Thermal Regime: Ecological Implications under a Climate Change Context (open access)

Larval Development in Tropical Gar (Atractosteus tropicus) Is Dependent on the Embryonic Thermal Regime: Ecological Implications under a Climate Change Context

Article presents research on how temperature affects fish populations. The study shows how changes in temperature may induce craniofacial and morphological alterations in fish during early stages and contribute to understanding the possible effects of global warming in early development of fish and its ecological implications.
Date: December 14, 2021
Creator: Cordova-de la Cruz, Simrith E.; Riesco, Marta F.; Martínez-Bautista, Gil; Calzada-Ruiz, Daniel; Martínez-Burguete, Talhia; Peña-Marín, Emyr S. et al.
Object Type: Article
System: The UNT Digital Library
Gas-Phase Chemistry of 1,1,2,3,3,4,4-Heptafluorobut-1-ene Initiated by Chlorine Atoms (open access)

Gas-Phase Chemistry of 1,1,2,3,3,4,4-Heptafluorobut-1-ene Initiated by Chlorine Atoms

This article uses the relative rate method to determine the rate constant for the reaction of heptafluorobut-1-ene (CF₂=CFCF₂CF₂H) with chlorine atoms in air.
Date: December 29, 2021
Creator: Sapkota, Ramesh & Marshall, Paul
Object Type: Article
System: The UNT Digital Library
Cascading effects of COVID-19 on population mobility and air quality: An exploration including place characteristics using geovisualization (open access)

Cascading effects of COVID-19 on population mobility and air quality: An exploration including place characteristics using geovisualization

Article examining the population mobility and air quality before and after the lockdown (mandated restriction of activity) during the public health response to COVID-19. This article is part of the Special Issue on COVID-19.
Date: January 22, 2022
Creator: Atkinson, Samuel F.; Kala, Abhishek K. & Tiwari, Chetan
Object Type: Article
System: The UNT Digital Library
Abraham Model Descriptors for Melatonin; Prediction of Solution, Biological and Thermodynamic Properties (open access)

Abraham Model Descriptors for Melatonin; Prediction of Solution, Biological and Thermodynamic Properties

Article using literature solubilities to obtain properties or descriptors of melatonin.
Date: January 27, 2022
Creator: Liu, Xiangli; Abraham, M. H. (Michael H.) & Acree, William E. (William Eugene)
Object Type: Article
System: The UNT Digital Library
Inhaled diesel exhaust particles result in microbiome‑related systemic inflammation and altered cardiovascular disease biomarkers in C57Bl/6 male mice (open access)

Inhaled diesel exhaust particles result in microbiome‑related systemic inflammation and altered cardiovascular disease biomarkers in C57Bl/6 male mice

Article discusses the authors' investigation the hypothesis that exposure to inhaled diesel exhaust particles alters the gut microbiome and promotes microbial-related inflammation and cardiovascular disease biomarkers. To determine whether probiotics could prevent diet or DEP exposure mediated alterations in the gut microbiome or systemic outcomes, a subset of animals on the HF diet were treated orally with 0.3 g/day (~ 7.5 × 108 CFU/day) of Winclove Ecologic® Barrier probiotics throughout the study.
Date: February 9, 2022
Creator: Phillippi, Danielle T.; Daniel, Sarah; Pusadkar, Vaidehi; Youngblood, Victoria L.; Nguyen, Kayla N.; Azad, Rajeev K. et al.
Object Type: Article
System: The UNT Digital Library
Transcriptome Analysis Uncovers the Gene Expression Profile of Hemileia vastatrix (Race XXXIII) during the Interactions with Resistant and Susceptible Coffee (open access)

Transcriptome Analysis Uncovers the Gene Expression Profile of Hemileia vastatrix (Race XXXIII) during the Interactions with Resistant and Susceptible Coffee

This article presents research to sequence the transcriptome of H. vastatrix race XXXIII to obtain a database for use as a reference in studies of the interaction between the fungus and coffee. In addition, the authors aim to identify differentially expressed genes that have the potential to act as effector proteins during the interaction.
Date: December 27, 2021
Creator: Castro, Isabel Samila Lima; Freitas-Lopes, Rejane do Livramento; de Siqueira Ferreira, Sávio; Maciel, Talles Eduardo Ferreira; Florez, Juan Carlos; Zambolim, Eunize Maciel et al.
Object Type: Article
System: The UNT Digital Library
Air pollution and endocrine disruptors induce human microbiome imbalances: A systematic review of recent evidence and possible biological mechanisms (open access)

Air pollution and endocrine disruptors induce human microbiome imbalances: A systematic review of recent evidence and possible biological mechanisms

Article presents a systematic review examining the scientific evidence on the effect of environmental toxicants, air pollutants and endocrine disruptors (EDCs), on compositional and diversity of human microbiota.
Date: February 11, 2022
Creator: Mousavi, Sayed Esmaeil; Delgado-Saborit, Juana Maria; Adivi, Anna; Pauwels, Sara & Godderis, Lode
Object Type: Article
System: The UNT Digital Library
Soft Metal Cations Trigger Sandwich-Cluster Luminescence of a New Au(I)-Vinylimidazolate Cyclic Trinuclear Complex (open access)

Soft Metal Cations Trigger Sandwich-Cluster Luminescence of a New Au(I)-Vinylimidazolate Cyclic Trinuclear Complex

Article presenting results from a study where a new gold(I)-vinylimidazolate CTC, 1, was prepared and the formation of highly emissive sandwich adducts with the soft metal cations Cu+, Ag+, and Tl+, 2–4, respectively, was investigated.
Date: February 14, 2022
Creator: Lu, Zhou; Burini, Alfredo; McDougald, Roy N., Jr.; Ricci, Simone; Luciani, Lorenzo; Nesterov, Vladimir N. et al.
Object Type: Article
System: The UNT Digital Library
Soft Metal Cations Trigger Sandwich-Cluster Luminescence of a New Au(I)-Vinylimidazolate Cyclic Trinuclear Complex (open access)

Soft Metal Cations Trigger Sandwich-Cluster Luminescence of a New Au(I)-Vinylimidazolate Cyclic Trinuclear Complex

Article presenting research that obtained a new Au(I) CTC bearing the 1-vinylimidazolate ligand and furthered the controllable synthetic pathway to afford heterometallic sandwich-like clusters.
Date: February 14, 2022
Creator: Lu, Zhou; Burini, Alfredo; McDougald, Roy N., Jr.; Ricci, Simone; Luciani, Lorenzo; Nesterov, Vladimir N. et al.
Object Type: Article
System: The UNT Digital Library
Unusual Properties of Hydrogen-Bonded Ferroelectrics: The Case of Cobalt Formate (open access)

Unusual Properties of Hydrogen-Bonded Ferroelectrics: The Case of Cobalt Formate

Article using first-principles simulations to predict room temperature ferroelectricity in a representative of the formate family, [NH₂NH₃][Co(HCOO)₃].
Date: February 18, 2022
Creator: Ghosh, P. S.; DeTellem, D.; Ren, J.; Witanachchi, S.; Ma, Shengqian; Lisenkov, S. et al.
Object Type: Article
System: The UNT Digital Library
Efficient oral insulin delivery enabled by transferrin-coated acid-resistant metal-organic framework nanoparticles (open access)

Efficient oral insulin delivery enabled by transferrin-coated acid-resistant metal-organic framework nanoparticles

Article uses acid-resistant metal-organic framework nanoparticles (UiO-68-NH2) to encapsulate sufficient insulin and decorated the exterior with targeting proteins (transferrin) to realize highly efficient oral insulin delivery.
Date: September 20, 2021
Creator: Zou, Jun-Jie; Wei, Gaohui; Xiong, Chuxiao; Yu, Yunhao; Li, Sihui; Hu, Liefeng et al.
Object Type: Article
System: The UNT Digital Library
In vivo Evaluation of Non-viral NICD Plasmid-Loaded PLGA Nanoparticles in Developing Zebrafish to Improve Cardiac Functions (open access)

In vivo Evaluation of Non-viral NICD Plasmid-Loaded PLGA Nanoparticles in Developing Zebrafish to Improve Cardiac Functions

This article presents a study with the purpose to deliver a Notch Intracellular Domain (NICD)-encoded plasmid via poly(lactic-co-glycolic acid) (PLGA) nanoparticles and to investigate the toxic environmental side effects for an in vivo experiment. This research demonstrates that PLGA nanoparticle-mediated target delivery to upregulate Notch related genes can be a potential therapeutic approach with minimum toxic effects.
Date: February 23, 2022
Creator: Messerschmidt, Victoria L.; Chintapula, Uday; Bonetesta, Fabrizio; Laboy-Segarra, Samantha; Naderi, Amir; Nguyen, Kytai T. et al.
Object Type: Article
System: The UNT Digital Library
Better together: Protein partnerships for lineage-specific oil accumulation (open access)

Better together: Protein partnerships for lineage-specific oil accumulation

Article reviews recent evidence that protein–protein interactions in each of the three major phases of oil formation appear to have profound effects on specialized oil accumulation. This article is part of the special issue: Physiology and metabolism (2022).
Date: February 24, 2022
Creator: Busta, Lucas; Chapman, Kent Dean & Cahoon, Edgar B.
Object Type: Article
System: The UNT Digital Library
Two-Layer High-Throughput: Effective Mass Calculations Including Warping (open access)

Two-Layer High-Throughput: Effective Mass Calculations Including Warping

Article performing and analyzing two-layer high-throughput calculations.
Date: February 26, 2022
Creator: Supka, Andrew; Mecholsky, Nicholas A.; Buongiorno Nardelli, Marco; Curtarolo, Stefano & Fornari, Marco
Object Type: Article
System: The UNT Digital Library
Transgenic manipulation of triacylglycerol biosynthetic enzymes in B. napus alters lipid-associated gene expression and lipid metabolism (open access)

Transgenic manipulation of triacylglycerol biosynthetic enzymes in B. napus alters lipid-associated gene expression and lipid metabolism

Article asserts that oilseed rape (Brassica napus) is an important crop that is cultivated for the oil (mainly triacylglycerol; TAG) it produces in its seeds. The author's results show that up-regulation of these key enzymes differentially affects lipid composition and distribution as well as lipid-associated gene expression, providing important information which could be used to improve crop properties by metabolic engineering.
Date: March 1, 2022
Creator: Liao, Pan; Lechon, Tamara; Romsdahl, Trevor; Woodfield, Helen K.; Fenyk, Stepan; Fawcett, Tony et al.
Object Type: Article
System: The UNT Digital Library
Gene-based association tests using GWAS summary statistics and incorporating eQTL (open access)

Gene-based association tests using GWAS summary statistics and incorporating eQTL

Article proposes a powerful and computationally efficient gene-based association test, called Overall. Using extended Simes procedure, Overall aggregates information from three types of traditional gene-based association tests and also incorporates expression quantitative trait locus (eQTL) information into a gene-based association test using GWAS summary statistics. The results show that this newly developed method can identify more significant genes than other methods.
Date: March 3, 2022
Creator: Cao, Xuwei; Wang, Xuexia; Zhang, Shuanglin & Sha, Qiuying
Object Type: Article
System: The UNT Digital Library
Solubility of tadalafil in aqueous mixtures of Transcutol® and PEG 400 revisited: correlation, thermodynamics and preferential solvation (open access)

Solubility of tadalafil in aqueous mixtures of Transcutol® and PEG 400 revisited: correlation, thermodynamics and preferential solvation

Article analyzing mole fraction solubilities of tadalafil (3) in aqueous mixtures of Transcutol® and PEG 400 at temperatures from 298.15 to 333.15 K following Hildebrand solubility parameters.
Date: February 16, 2022
Creator: Shakeel, Faiyaz; Alshehri, Sultan; Ghoneim, Mohammed M.; Martínez, Fleming; Peña, María Á.; Jouyban, Abolghasem et al.
Object Type: Article
System: The UNT Digital Library

Flipped and Free: an inverted, active-learning general chemistry course using exclusively OER

Presentation on using a flipped course format and including an open textbook, OpenStax: Chemistry 2e. Flipped courses provide lecture content that is accessible online, and they use class time for active learning activities. It is a part of 2022 University of North Texas Open Access Symposium that was held on March 8, 2022.
Date: March 8, 2022
Creator: Petros, Amy K.
Object Type: Presentation
System: The UNT Digital Library
Developmental changes in lignin composition are driven by both monolignol supply and laccase specificity (open access)

Developmental changes in lignin composition are driven by both monolignol supply and laccase specificity

Article proposes a model in which, during C-lignin biosynthesis, caffeyl alcohol noncompetitively inhibits oxidation of coniferyl alcohol by cell wall laccases, a process that might limit movement of coniferyl alcohol to the apoplast.
Date: October 13, 2021
Creator: Zhou, Chunliu; Wang, Xin; Docampo-Palacios, Maite; Sanders, Brian C.; Engle, Nancy L.; Tschaplinski, Timothy J. et al.
Object Type: Article
System: The UNT Digital Library