CancerNet: a unified deep learning network for pan‑cancer diagnostics (open access)

CancerNet: a unified deep learning network for pan‑cancer diagnostics

Article states that despite remarkable advances in cancer research, cancer remains one of the leading causes of death worldwide. The author's proposed framework for cancer diagnostics detects cancers and their tissues of origin using a unified model of cancers encompassing 33 cancers represented in The Cancer Genome Atlas. Their model exploits the learned features of different cancers reflected in the respective dysregulated epigenomes, holding a great promise in early cancer detection.
Date: June 13, 2022
Creator: Gore, Steven & Azad, Rajeev K.
System: The UNT Digital Library
The flexibility of proanthocyanidin biosynthesis in plants (open access)

The flexibility of proanthocyanidin biosynthesis in plants

Article presents research that explores proanthocyanidin (PA) biosynthesis routes in plants. The data suggests that different species have evolved different routes for PA biosynthesis.
Date: June 13, 2022
Creator: Lu, Nan; Jun, Ji Hyung; Liu, Chenggang & Dixon, R. A.
System: The UNT Digital Library
A role for ascorbate conjugates of (+)-catechin in proanthocyanidin polymerization (open access)

A role for ascorbate conjugates of (+)-catechin in proanthocyanidin polymerization

Article describes how both biochemically and genetically, that ascorbate (AsA) is an alternative “starter unit” to flavan-3-ol monomers for leucocyanidin-derived (+)-catechin subunit extension in the Arabidopsis thaliana anthocyanidin synthase (ans) mutant. The authors' findings advance the knowledge of (+)-catechin-type PA extension and indicate that PA oligomerization does not necessarily proceed by sequential addition of a single extension unit. AsA-[C]n defines a new type of PA intermediate which we term “sub-PAs”.
Date: June 14, 2022
Creator: Yu, Keji; Dixon, R. A. & Duan, Changquing
System: The UNT Digital Library
Transcriptome of Endophyte-Positive and Endophyte-Free Tall Fescue Under Field Stresses (open access)

Transcriptome of Endophyte-Positive and Endophyte-Free Tall Fescue Under Field Stresses

This article is a study that represents the first transcriptome analysis of E+ and E− Texoma tall fescue under freezing and chilling temperatures in the natural field environment.
Date: June 14, 2022
Creator: Islam, Shofiqul; Krom, Nick; Kwon, Taegun; Li, Guifen & Saha, Malay
System: The UNT Digital Library
Lipidomic Analysis of Arabidopsis T-DNA Insertion Lines Leads to Identification and Characterization of C-Terminal Alterations in FATTY ACID DESATURASE 6 (open access)

Lipidomic Analysis of Arabidopsis T-DNA Insertion Lines Leads to Identification and Characterization of C-Terminal Alterations in FATTY ACID DESATURASE 6

Article states that mass-spectrometry-based screening of lipid extracts of wounded and unwounded leaves from a collection of 364 Arabidopsis thaliana T-DNA insertion lines produced lipid profiles that were scored on the number and significance of their differences from the leaf lipid profiles of wild-type plants. The analysis identified Salk_109175C, which displayed alterations in leaf chloroplast glycerolipid composition, including a decreased ratio between two monogalactosyldiacylglycerol (MGDG) molecular species, MGDG(18:3/16:3) and MGDG(18:3/18:3).
Date: June 21, 2022
Creator: Lusk, Hannah J.; Neumann, Nicholas; Colter, Madeline; Roth, Mary R.; Tamura, Pamela; Yao, Libin et al.
System: The UNT Digital Library
Sustaining Human Nutrition in an Increasingly Urban World (open access)

Sustaining Human Nutrition in an Increasingly Urban World

This article proposes an urban nutrition (UN) extension to the previously published urban ecological economic system. The proposed extension can be used by decision makers worldwide to evaluate how landscape configurations and agricultural production systems affect the nutritional needs of the local population while fostering sustainable practices.
Date: June 22, 2022
Creator: Torres, Angélica Valencia; Tiwari, Chetan & Atkinson, Samuel F.
System: The UNT Digital Library