N-acylethanolamide metabolizing enzymes are upregulated in human neural progenitor-derived neurons exposed to sub-lethal oxidative stress (open access)

N-acylethanolamide metabolizing enzymes are upregulated in human neural progenitor-derived neurons exposed to sub-lethal oxidative stress

Article is a study determining whether ReN cells, a superior cell model system for studying neurodevelopment, differentiation, and neuroprotection, express proteins involved in canonical eCB NAE signaling and whether oxidative stress can induce their expression. This study is a first step toward determining how oxidative stress affects CB1, CB2, FAAH, NAAA, and NAPE-PLD expression and their potential defense against oxidative stress.
Date: August 8, 2022
Creator: Duncan, Scott R.; Riordan, Sean M.; Hall, Conner W.; Payne, Andrew J.; Chapman, Kent Dean & Koulen, Peter
Object Type: Article
System: The UNT Digital Library
Genetically engineered probiotic for the treatment of phenylketonuria (PKU); assessment of a novel treatment in vitro and in the PAHᵉⁿᵘ² mouse model of PKU (open access)

Genetically engineered probiotic for the treatment of phenylketonuria (PKU); assessment of a novel treatment in vitro and in the PAHᵉⁿᵘ² mouse model of PKU

This article describes the testing of a phenylalanine lyase gene from Anabaena variabilis (AvPAL) codon-optimized and cloned into a shuttle vector for expression in Lactobacillus reuteri 100-23C (pHENOMMenal).
Date: May 17, 2017
Creator: Durrer, Katherine E.; Allen, Michael S. & Hunt von Herbing, Ione
Object Type: Article
System: The UNT Digital Library
Genetic Differentiation of the South Florida Red-Shouldered Hawk (Buteo lineatus extimus) from the Nominate Subspecies (Buteo lineatus lineatus) (open access)

Genetic Differentiation of the South Florida Red-Shouldered Hawk (Buteo lineatus extimus) from the Nominate Subspecies (Buteo lineatus lineatus)

Article discusses how the south Florida subspecies of the Red-shouldered Hawk (Buteo lineatus extimus) is distinctly paler and smaller than other subspecies, reproduces at a lower rate, and can occupy very different habitats such as open marshes and grasslands with only scattered trees. The authors evaluated population differentiation between the south Florida population of Red-shouldered Hawks and two populations of eastern Red-shouldered Hawks (B. l. lineatus) in suburban (Cincinnati) and rural (Hocking Hills) environments in southern Ohio.
Date: March 1, 2023
Creator: Dykstra, Madeline A.; Marain, Donna M.; Wrona, Anna M.; Dysktra, Cheryl R.; Farrington, Heather L.; Johnson, Jeff A. et al.
Object Type: Article
System: The UNT Digital Library
Thermal Stress Has Minimal Effects on Bacterial Communities of Thermotolerant Symbiodinium Cultures (open access)

Thermal Stress Has Minimal Effects on Bacterial Communities of Thermotolerant Symbiodinium Cultures

Article comparing the microbial communities of three isolates from different species of the genus Symbiodinium (formerly known as Symbiodinium clade A) with different ecophysiology, levels of interaction with the animal host, and thermal adaptations. Results suggest that bacteria associated or co-cultured with thermotolerant Symbiodinium might play an important role in thermotolerance.
Date: May 19, 2022
Creator: Díaz-Almeyda, Erika M.; Ryba, Tyrone; Ohdera, Aki H.; Shafer, Natali; Link, Caroline; Prado-Zapata, Marcela et al.
Object Type: Article
System: The UNT Digital Library
DNA metabarcoding captures different macroinvertebrate biodiversity than morphological identification approaches across a continental scale (open access)

DNA metabarcoding captures different macroinvertebrate biodiversity than morphological identification approaches across a continental scale

Article describes how DNA-based aquatic biomonitoring methods show promise to provide rapid, standardized, and efficient biodiversity assessment to supplement and in some cases replace current morphology-based approaches that are often less efficient and can produce inconsistent results. The authors present a comparison of DNA metabarcoding and morphological identification, leveraging national-scale, open-source, ecological datasets from the National Ecological Observatory Network.
Date: July 19, 2023
Creator: Emmons, Sean C.; Compson, Zacchaeus Greg; Malish, Megan C.; Busch, Michelle H.; Saenz, Veronica; Higgins, Kierstyn T. et al.
Object Type: Article
System: The UNT Digital Library
Frontiers in Aquatic Physiology – grand challenge (open access)

Frontiers in Aquatic Physiology – grand challenge

Opinion article covering grand challenges to aquatic physiology based on the five "grand challenges in organismal biology" proposed by Schwenk et al. (2007). This article also provides a list of specific examples of emerging areas of research interest in aquatic physiology.
Date: May 18, 2010
Creator: Evans, David H.; Axelsson, Michael; Beltz, Barbara; Burggren, Warren W.; Castellini, Michael; Clements, Kendall D. et al.
Object Type: Article
System: The UNT Digital Library
The metabolic cost of turning right side up in the Mediterranean spur-thighed tortoise (Testudo graeca) (open access)

The metabolic cost of turning right side up in the Mediterranean spur-thighed tortoise (Testudo graeca)

Article examining the the metabolic cost of self-righting in the terrestrial Mediterranean spur-thighed tortoise using respirometry and kinematic video analysis and comparing this to the metabolic cost of locomotion at a moderate, easily sustainable speed. The results found that self-righting is, relatively, metabolically expensive and costs around two times the mass-specific power required to walk.
Date: January 10, 2022
Creator: Ewart, Heather E.; Tickle, Peter G.; Sellers, William I.; Lambertz, Markus; Crossley, Dane A., II & Codd, Jonathan R.
Object Type: Article
System: The UNT Digital Library
Mediterranean Spur-Thighed Tortoises (Testudo graeca) Have Optimal Speeds at Which They Can Minimise the Metabolic Cost of Transport, on a Treadmill (open access)

Mediterranean Spur-Thighed Tortoises (Testudo graeca) Have Optimal Speeds at Which They Can Minimise the Metabolic Cost of Transport, on a Treadmill

Article experimentally quantifies the metabolic cost of transport in Mediterranean spur-thighed tortoises walking on a treadmill while also quantifying the kinematics of their movement. Results found that tortoises move more efficiently than predicted and presents the first data demonstrating a curvilinear cost of transport over their speed range. The authors conclude that tortoises have an optimum speed at which they move to minimise their metabolic cost of locomotion.
Date: July 13, 2022
Creator: Ewart, Heather; Tickle, Peter; Nudds, Robert; Sellers, William; Crossley, Dane A., II & Codd, Jonathan
Object Type: Article
System: The UNT Digital Library
Generation of transgenic zebrafish with 2 populations of RFP- and GFP-labeled thrombocytes: analysis of their lipids (open access)

Generation of transgenic zebrafish with 2 populations of RFP- and GFP-labeled thrombocytes: analysis of their lipids

Article analyzing the lipids in transgenic zebrafish. Separating RFP+ and GFP+ thrombocytes from the GloFli fish developed here led to the analysis of their lipid composition.DiI-labeled liposomes with similar PE and PC concentrations found in RFP+ thrombocytes explained DiI labeling of thrombocytes.
Date: July 23, 2018
Creator: Fallatah, Weam; De Silva, Imesha W.; Verbeck, Guido F. & Jagadeeswaran, Pudur
Object Type: Article
System: The UNT Digital Library
Analysis of transcribed sequences from young and mature zebrafish thrombocytes (open access)

Analysis of transcribed sequences from young and mature zebrafish thrombocytes

Article studying thrombocyte function and development in adult zebrafish. The authors performed single-cell RNA sequencing of the young and mature zebrafish thrombocytes and compared the two datasets for young and mature thrombocyte transcripts.
Date: September 19, 2021
Creator: Fallatah, Weam; De, Ronika; Burks, David J.; Azad, Rajeev K. & Jagadeeswaran, Pudur
Object Type: Article
System: The UNT Digital Library
A dynamic model of lignin biosynthesis in Brachypodium distachyon (open access)

A dynamic model of lignin biosynthesis in Brachypodium distachyon

This article proposes a dynamic mathematical model that integrates various datasets and other information regarding the lignin pathway in Brachypodium distachyon and permits explanations for some counterintuitive observations.
Date: September 19, 2018
Creator: Faraji, Mojdeh; Fonseca, Luis L.; Escamilla-Treviño, Luis; Barros, Jaime; Engle, Nancy L.; Yang, Zamin K. et al.
Object Type: Article
System: The UNT Digital Library
Mathematical Models of Lignin Biosynthesis (open access)

Mathematical Models of Lignin Biosynthesis

This article presents several computational models that can aid in the analysis of data characterizing lignin biosynthesis.
Date: February 9, 2018
Creator: Faraji, Mojdeh; Fonseca, Luis L.; Escamilla-Treviño, Luis; Barros, Jaime; Engle, Nancy L.; Yang, Zamin K. et al.
Object Type: Article
System: The UNT Digital Library
A dynamic model of lignin biosynthesis in Brachypodium distachyon (open access)

A dynamic model of lignin biosynthesis in Brachypodium distachyon

Article proposes a dynamic mathematical model that integrates various datasets and other information regarding the lignin pathway in Brachypodium distachyon and permits explanations for some counterintuitive observations.
Date: September 19, 2018
Creator: Faraji, Mojdeh; Fonseca, Luis L.; Escamilla-Treviño, Luis; Barros-Rios, Jaime; Engle, Nancy L.; Yang, Zamin K. et al.
Object Type: Article
System: The UNT Digital Library
Mathematical models of lignin biosynthesis (open access)

Mathematical models of lignin biosynthesis

Article presents several computational models than can aid in the analysis of data characterizing lignin biosynthesis.
Date: February 9, 2018
Creator: Faraji, Mojdeh; Fonseca, Luis L.; Escamilla-Treviño, Luis; Barros-Rios, Jaime; Engle, Nancy L.; Yang, Zamin K. et al.
Object Type: Article
System: The UNT Digital Library
Gold Nanoparticles-enabled Efficient Dual Delivery of Anticancer Therapeutics to HeLa Cells (open access)

Gold Nanoparticles-enabled Efficient Dual Delivery of Anticancer Therapeutics to HeLa Cells

This article describes a facile one-step method to synthesize stable collodial gold nanoparticles (AuNPs) loaded with a combination of two anticancer therapeutics, -bleomycin and doxorubicin
Date: September 20, 2017
Creator: Farooq, Muhammad U.; Novosad, Valentyn; Rozhkova, Elena A.; Wali, Hussain; Ali, Asghar; Fateh, Ahmed A. et al.
Object Type: Article
System: The UNT Digital Library
Retraction Note: Gold Nanoparticles‑enabled Efficient Dual Delivery of Anticancer Therapeutics to HeLa cells (open access)

Retraction Note: Gold Nanoparticles‑enabled Efficient Dual Delivery of Anticancer Therapeutics to HeLa cells

The editors have retracted their article Gold Nanoparticles-enabled Efficient Dual Delivery of Anticancer Therapeutics to HeLa cells. Concerns were brought to the attention of the Editors with respect to apparent inappropriate manipulation of the data in seven of the nine panels shown in Figure 7. The Editors no longer have confidence in the data reported in this Article.
Date: July 5, 2022
Creator: Farooq, Muhammad U.; Novosad, Valentyn; Rozhkova, Elena A.; Wali, Hussain; Ali, Asghar; Fateh, Ahmed A. et al.
Object Type: Article
System: The UNT Digital Library
Overexpression of phospholipid: diacylglycerol acyltransferase in Brassica napus results in changes in lipid metabolism and oil accumulation (open access)

Overexpression of phospholipid: diacylglycerol acyltransferase in Brassica napus results in changes in lipid metabolism and oil accumulation

Article studying the regulation of lipid metabolism in oilseeds.
Date: March 31, 2022
Creator: Fenyk, Stepan; Woodfield, Helen K.; Romsdahl, Trevor B.; Wallington, Emma J.; Bates, Ruth E.; Fell, David A. et al.
Object Type: Article
System: The UNT Digital Library
Using CRISPR/Cas to enhance gene expression for crop trait improvement by editing miRNA targets (open access)

Using CRISPR/Cas to enhance gene expression for crop trait improvement by editing miRNA targets

Article states that gene editing tools such as CRISPR/Cas9 are often thought of as a means to prevent gene expression; however, a more subtle and yet powerful approach is the enhancement of gene expression by precise deletion of repressor sites within a gene of interest. Authors argue that gene editing of miRNA target sites is preferable over deletion of the miRNA genes themselves, given that it avoids the pitfalls of unspecific derepression of miRNA target(s) beyond the gene of interest.
Date: January 10, 2023
Creator: Ferreira, Savio S. & Reis, Rodrigo S.
Object Type: Article
System: The UNT Digital Library
In silico guided structural and functional analysis of genes with potential involvement in resistance to coffee leaf rust: A functional marker based approach (open access)

In silico guided structural and functional analysis of genes with potential involvement in resistance to coffee leaf rust: A functional marker based approach

Article presents novel insights into the molecular nature of the SH genes, thereby opening new avenues for coffee rust resistance molecular breeding.
Date: July 8, 2020
Creator: Ferreira, Svio Siqueira; Barka, Geleta Dugassa; Caixeta, Eveline Teixeira & Zambolim, Larcio
Object Type: Article
System: The UNT Digital Library
MYB30 Orchestrates Systemic Reactive Oxygen Signaling and Plant Acclimation (open access)

MYB30 Orchestrates Systemic Reactive Oxygen Signaling and Plant Acclimation

This article explores the relationship among MYB30, the ROS wave, and systemic acclimation in Arabidopsis by determining the SAA response to HL stress of MYB30 mutants and wild-type plants.
Date: July 22, 2020
Creator: Fichman, Yosef; Zandalinas, Sara I.; Sengupta, Soham; Burks, David J.; Meyers, Ronald J., Jr.; Azad, Rajeev K. et al.
Object Type: Article
System: The UNT Digital Library
Beyond the Chicken: Alternative Avian Models for Developmental Physiological Research (open access)

Beyond the Chicken: Alternative Avian Models for Developmental Physiological Research

This article is a review examining the characteristics that make an animal model attractive for developmental research and explores opportunities presented by the embryo to adult continuum of alternative bird models including quail, ratites, songbirds, birds of prey, and corvids.
Date: October 21, 2021
Creator: Flores-Santin, Josele & Burggren, Warren W.
Object Type: Article
System: The UNT Digital Library
Loss of Migratory Traditions Makes the Endangered Patagonian Huemul Deer a Year-Round Refugee in Its Summer Habitat (open access)

Loss of Migratory Traditions Makes the Endangered Patagonian Huemul Deer a Year-Round Refugee in Its Summer Habitat

This article analyzes the historical spatiotemporal behavior of the huemul (Hippocamelus bisulcus), an endangered deer endemic to Patagonia. Losing migratory traditions is a major threat, and may explain their presently prevalent skeletal diseases, reduced longevity, and lacking recolonizations for most remaining huemul subpopulations.
Date: May 31, 2022
Creator: Flueck, Werner T.; Smith-Flueck, Jo Anne M.; Escobar, Miguel E.; Zuliani, Melina; Fuchs, Beat; Geist, Valerius et al.
Object Type: Article
System: The UNT Digital Library
An Arabidopsis Oxalyl-CoA Decarboxylase, AtOXC, Is Important for Oxalate Catabolism in Plants (open access)

An Arabidopsis Oxalyl-CoA Decarboxylase, AtOXC, Is Important for Oxalate Catabolism in Plants

This article identifies, in Arabidopsis, an oxalyl-CoA decarboxylase (AtOXC) that is capable of catalyzing the second step in the proposed pathway of oxalate catabolism.
Date: March 23, 2021
Creator: Foster, Justin; Cheng, Ninghui; Paris, Vincent; Wang, Lingfei; Wang, Jin; Wang, Xiaoqiang et al.
Object Type: Article
System: The UNT Digital Library
Fatty acid amide hydrolase and 9-lipoxygenase  modulate cotton seedling growth by ethanolamide  oxylipin levels (open access)

Fatty acid amide hydrolase and 9-lipoxygenase modulate cotton seedling growth by ethanolamide oxylipin levels

Article asserts that polyunsaturated N-acylethanolamines (NAEs) can be hydrolyzed by fatty acid amide hydrolase (FAAH) or oxidized by lipoxygenase (LOX). Altogether, the authors conclude that the growth of cotton seedlings involves fine-tuning of 9-NAE-HOD levels via FAAH-mediated hydrolysis and LOX-mediated production, expanding the mechanistic understanding of plant growth modulation by NAE oxylipins to a perennial crop species.
Date: December 6, 2022
Creator: Gaguancela-Arias, Omar; Aziz, Mina & Chapman, Kent Dean
Object Type: Article
System: The UNT Digital Library