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369 Matching Results
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Development, Validation, and Application of the Microbiology Concept Inventory
This article describes the creation and validation of a new microbiology concept inventory using the American Society for Microbiology Curriculum Guidelines.
Date:
October 5, 2017
Creator:
Paustian, Timothy D.; Briggs, Amy G.; Brennan, R. E.; Boury, Nancy; Buchner, John; Harris, Shannon et al.
Object Type:
Article
System:
The UNT Digital Library
Toward Best Management Practices for Ecological Corridors
This article summarizes the best available information about managing ecological corridor systems. The aim with is to provide managers with a convenient guidance document and tool to assist in applying scientific management principles to management of corridors. It does not cover issues related to corridor design or political buy in, but focuses on how a corridor should be managed once it has been established.
Date:
February 1, 2021
Creator:
Gregory, Andrew; Spence, Emma; Beier, Paul & Garding, Emily
Object Type:
Article
System:
The UNT Digital Library
Sub-Antarctic Freshwater Invertebrate Thermal Tolerances: An Assessment of Critical Thermal Limits and Behavioral Responses
Describes study which assessed the upper (CTmax) and lower (CTmin) thermal limits of three freshwater macroinvertebrate taxa with restricted low elevation distribution (20 m a.s.l.) and three taxa restricted to upper elevations (480 and 700 m a.s.l.) in the Magellanic sub-Antarctic ecoregion of southern Chile, and argues that their low tolerance to temperature increase can make them useful as indicators of thermal alteration in their habitats.
Date:
February 4, 2020
Creator:
Rendoll Cárcamo, Javier; Contador, Tamara; Convey, Peter & Kennedy, James H.
Object Type:
Article
System:
The UNT Digital Library
Extensive shared polymorphism at non-MHC immune genes in recently diverged North American prairie grouse
This article investigates the patterns of shared polymorphism and selection at non-MHC immune genes in five grouse species from Centrocercus and Tympanuchus genera.
Date:
August 2, 2017
Creator:
Minias, Piotr; Bateson, Zachary W.; Whittingham, Linda A.; Johnson, Jeff A.; Oyler-McCance, Sara & Dunn, Peter O.
Object Type:
Article
System:
The UNT Digital Library
Isorhamnetin Inhibits Proliferation and Invasion and Induces Apoptosis through the Modulation of Peroxisome Proliferator-activated Receptor γ Activation Pathway in Gastric Cancer
Article investigating the potential effects of isorhamnetin (IH), a 3′-O-methylated metabolite of quercetin on the peroxisome proliferator-activated receptor γ (PPAR-γ) signaling cascade using proteomics technology platform, GC cell lines, and xenograft mice model. The study y proposes a novel agent for gastric cancer treatment.
Date:
November 2, 2012
Creator:
Ramachandran, Lalitha; Manu, Kanjoormana Aryan; Shanmugam, Muthu K.; Li, Feng; Siveen, Kodappully Sivaraman; Vali, Shireen et al.
Object Type:
Article
System:
The UNT Digital Library
Malonylation of Glucosylated N-Lauroylethanolamine: A New Pathway That Determines N-Acylethanolamine Metabolic Fate in Plants
Article studying Malonylation of Glucosylated N-Lauroylethanolamine. Results indicate that glucosylation of NAE 12:0 by a yet to be determined glucosyltransferase and its subsequent malonylation by PMAT1 could represent a mechanism for modulating the biological activities of NAEs in plants.
Date:
December 30, 2016
Creator:
Khan, Bibi Rafeiza; Wherritt, Daniel J.; Huhman, David; Sumner, Lloyd W.; Chapman, Kent Dean & Blancaflor, Elison B.
Object Type:
Article
System:
The UNT Digital Library
The Unique Fold and Lability of the [2fe‑2s] Clusters of Neet Proteins Mediate Their Key Functions in Health and Disease
This article discusses the NEET fold and its structural elements.
Date:
February 12, 2018
Creator:
Karmi, Ola; Marjault, Henri-Baptiste; Pesce, Luca; Carloni, Paolo; Onuchic, José N.; Jennings, Patricia A. et al.
Object Type:
Article
System:
The UNT Digital Library
Structural analysis of a plant fatty acid amide hydrolase provides insights into the evolutionary diversity of bioactive acylethanolamides
Article reporting the three-dimensional crystal structures of the signal-terminating enzyme fatty acid amide hydrolase (FAAH) from Arabidopsis in its apo and ligand-bound forms at 2.1- and 3.2-Å resolutions, respectively.
Date:
March 20, 2019
Creator:
Aziz, Mina; Wang, Xiaoqiang; Tripathi, Ashutosh; Bankaitis, Vytas A. & Chapman, Kent Dean
Object Type:
Article
System:
The UNT Digital Library
Scaling of axial muscle architecture in juvenile Alligator mississippiensis reveals an enhanced performance capacity of accessory breathing mechanisms
Article describing the anatomy of the trunk muscles, their properties that determine muscle performance (mass, length and physiological cross-sectional area [PCSA]) and investigating their scaling in juvenile Alligator mississippiensis spanning an order of magnitude in body mass (359 g–5.5 kg). Findings support existing anecdotal evidence that crocodilians shift their breathing mechanics as they increase in size.
Date:
July 23, 2021
Creator:
Rose, Kayleigh A. R.; Tickle, Peter G.; Elsey, Ruth M.; Sellers, William I.; Crossley, Dane A., II & Codd, Jonathan R.
Object Type:
Article
System:
The UNT Digital Library
The Water-Water Cycle Is Essential for Chloroplast Protection in the Absence of Stress
Article showing that knockdown Arabidopsis plants with suppressed expression of the key water-water cycle enzyme, thylakoid-attached copper/zinc superoxide dismutase (KD-SOD), are suppressed in their growth and development. This article provides e genetic evidence for the importance of the water-water cycle in protecting the photosynthetic apparatus of higher plants from photooxidative damage.
Date:
October 3, 2003
Creator:
Rizhsky, Ludmila; Liang, Hongjian & Mittler, Ron
Object Type:
Article
System:
The UNT Digital Library
Function of Conserved Residues of Human Glutathione Synthetase: Implications for the ATP-Grasp Enzymes
Article examining the mechanism of Glutathione synthetase, an enzyme that belongs to the glutathione synthetase ATP-binding domain-like superfamily. A variety of structural alignment methods were applied and four highly conserved residues of human glutathione synthetase (Glu-144, Asn-146, Lys-305, and Lys-364) were identified in the binding site. The function of these was studied by experimental and computational site-directed mutagenesis.
Date:
May 21, 2004
Creator:
Dinescu, Adriana; Cundari, Thomas R., 1964-; Bhansali, Vikas S.; Luo, Jia-Li & Anderson, Mary E.
Object Type:
Article
System:
The UNT Digital Library
Temperature-sensitive Post-translational Regulation of Plant Omega-3 Fatty-acid Desaturases Is Mediated by the Endoplasmic Reticulum-associated Degradation Pathway
Article expressing two closely related plant FAD3 genes in yeast cells and found that their enzymes produced significantly different amounts of omega-3 fatty acids and that these differences correlated to differences in rates of protein turnover. The findings indicate that Fad3 protein abundance is regulated by a combination of cis-acting degradation signals and the ubiquitin-proteasome pathway and that modulation of Fad3 protein amounts in response to temperature may represent one mechanism of homeoviscous adaptation in plants.
Date:
July 9, 2010
Creator:
O'Quin, Jami B.; Bourassa, Linda; Zhang, Daiyuan; Shockey, Jay M.; Gidda, Satinder K.; Fosnot, Spencer et al.
Object Type:
Article
System:
The UNT Digital Library
Lipoxygenase-mediated Oxidation of Polyunsaturated N-Acylethanolamines in Arabidopsis
Article hypothesizing that lipoxygenase (LOX) participated in the metabolism of PU-NAEs through the formation of NAE-oxylipins. The data suggests that Arabidopsis LOXs indeed compete with FAAH to metabolize PU-NAEs during seedling establishment. Identification of endogenous amide-conjugated oxylipins suggests potential significance of these metabolites in vivo, and FAAH mutants may offer opportunities to address this in the future.
Date:
April 29, 2011
Creator:
Kilaru, Aruna; Herrfurth, Cornelia; Keereetaweep, Jantana; Hornung, Ellen; Venables, Barney J.; Feussner, Ivo et al.
Object Type:
Article
System:
The UNT Digital Library
The Transcriptional Co-activator MBF1c Is a Key Regulator of Thermotolerance in Arabidopsis thaliana
Article reporting that the highly conserved transcriptional co-activator, MBF1c (multiprotein bridging factor 1c), is a key regulator of thermotolerance in Arabidopsis thaliana. Results provide evidence for the existence of a tightly coordinated heat stress-response network, involving trehalose-, SA-, and ethylene-signaling pathways, that is under the control of MBF1c.
Date:
April 4, 2008
Creator:
Suzuki, Nobuhiro; Bajad, Sunil; Shuman, Joel; Shulaev, Vladimir & Mittler, Ron
Object Type:
Article
System:
The UNT Digital Library
Ascorbate Peroxidase 1 Plays a Key Role in the Response of Arabidopsis thaliana to Stress Combination
Article conducting proteomic and metabolic analysis of Arabidopsis thaliana plants subjected to a combination of drought and heat stress. The authors identify 45 different proteins that specifically accumulated in Arabidopsis in response to the stress combination. The findings suggest that cytosolic APX1 plays a key role in the acclimation of plants to a combination of drought and heat stress.
Date:
December 5, 2008
Creator:
Koussevitzky, Shai; Suzuki, Nobuhiro; Huntington, Serena; Armijo, Leigh; Sha, Wei; Cortes, Diego F. et al.
Object Type:
Article
System:
The UNT Digital Library
Visualization of Lipid Droplet Composition by Direct Organelle Mass Spectrometry
Article reporting an approach that combines the visualization of individual lipid droplets (LDs), microphase extraction of lipid components from droplets, and the direct identification of lipid composition by nanospray mass spectrometry, even to the level of a single LD. The triacylglycerol (TAG) composition of LDs from several plant sources (mature cotton (Gossypium hirsutum) embryos, roots of cotton seedlings, and Arabidopsis thaliana seeds and leaves) were examined by direct organelle mass spectrometry and revealed the heterogeneity of LDs derived from different plant tissue sources.
Date:
February 4, 2011
Creator:
Horn, Patrick J.; Ledbetter, Nicole R.; James, Christopher N.; Hoffman, William D.; Case, Charlene R.; Verbeck, Guido F. et al.
Object Type:
Article
System:
The UNT Digital Library
Compartmentation of Triacylglycerol Accumulation in Plants
Article studying an underappreciated complexity in pathways for synthesis and accumulation of Triacylglycerols from plants, familiar to most people as vegetable oils.
Date:
January 20, 2012
Creator:
Chapman, Kent Dean & Ohlrogge, John B.
Object Type:
Article
System:
The UNT Digital Library
The EAR-motif of the Cys2/His2-type Zinc Finger Protein Zat7 Plays a Key Role in the Defense Response of Arabidopsis to Salinity Stress
Article reporting that transgenic Arabidopsis plants constitutively expressing the Cys2/His2 zinc finger protein Zat7 have suppressed growth and are more tolerant to salinity stress. Findings demonstrate that the EAR-domain of Cys2/His2-type zinc finger proteins plays a key role in the defense response of Arabidopsis to abiotic stresses.
Date:
March 23, 2007
Creator:
Ciftci-Yilmaz, Sultan; Morsy, Mustafa R.; Song, Luhua; Coutu, Alicia; Krizek, Beth A.; Lewis, Michael W. et al.
Object Type:
Article
System:
The UNT Digital Library
Unraveling Δ1-Pyrroline-5-Carboxylate-Proline Cycle in Plants by Uncoupled Expression of Proline Oxidation Enzymes
Article showing that overexpression of MsProDH in tobacco and Arabidopsis or impairment of P5C oxidation in the Arabidopsis p5cdh mutant did not change the cellular Pro to P5C ratio under ambient and osmotic stress conditions, indicating that P5C excess was reduced to Pro in a mitochondrial-cytosolic cycle. Results show that normal oxidation of P5C to Glu by P5CDH is key to prevent P5C-Pro intensive cycling and avoid ROS production from electron run-off.
Date:
September 25, 2009
Creator:
Miller, Gad; Honig, Arik; Stein, Hanan; Suzuki, Nobuhiro; Mittler, Ron & Zilberstein, Aviah
Object Type:
Article
System:
The UNT Digital Library
Mutations in Arabidopsis Fatty Acid Amide Hydrolase Reveal That Catalytic Activity Influences Growth but Not Sensitivity to Abscisic Acid or Pathogens
Article showing that the enhanced growth and NAE tolerance of the AtFAAH overexpressing seedlings depends on the catalytic activity of AtFAAH, hypersensitivity to ABA and hypersusceptibility to nonhost pathogens are independent of its enzymatic activity. Findings suggest that the AtFAAH influences plant growth and interacts with ABA signaling and plant defense through distinctly different mechanisms.
Date:
December 4, 2009
Creator:
Kim, Sang-Chul; Kang, Li; Nagaraj, Satish; Blancaflor, Elison B.; Mysore, Kirankumar S. & Chapman, Kent D.
Object Type:
Article
System:
The UNT Digital Library
Activation of an S6/H4 Kinase (PAK 65) from Human Placenta by Intramolecular and Intermolecular Autophosphorylation
Article proposing a model in which phosphorylation of sites 1 and 2 occurs sequentially. The model proposes that trypsin treatment of the inactive holoenzyme removes an inhibitory rac-binding domain which blocks MgATP access to the catalytic site. The pseudosubstrate domain at site 1 is autophosphorylated and subsequent bimolecular autophosphorylation at site 2 fully opens the catalytic site.
Date:
September 8, 1995
Creator:
Benner, Gretchen E.; Dennis, Patrick B. & Masaracchia, Ruthann A.
Object Type:
Article
System:
The UNT Digital Library
Phosphorylation of Myosin Light Chain Kinase by p21-activated Kinase PAK2
Article reporting that PAK2, a member of the Rho family of GTPase-dependent kinases, regulates isometric tension development and myosin II RLC phosphorylation in saponin permeabilized endothelial monolayers. The results demonstrate that PAK2 can directly phosphorylate MLCK, inhibiting its activity and limiting the development of isometric tension.
Date:
June 16, 2000
Creator:
Goeckeler, Zoe M.; Masaracchia, Ruthann A.; Zeng, Qi; Chew, Teng-Leong; Gallagher, Patricia & Wysolmerski, Robert B.
Object Type:
Article
System:
The UNT Digital Library
Evaluation of Threshold Selection Methods for Adaptive Kernel Density Estimation in Disease Mapping
This article assesses the relative performance of threshold selection methods in terms of resolution and reliability for disease mapping.
Date:
May 8, 2018
Creator:
Ruckthongsook, Warangkana; Tiwari, Chetan; Oppong, Joseph R. & Natesan, Prathiba
Object Type:
Article
System:
The UNT Digital Library
Inhibition of Very Long Chain Fatty Acids Synthesis Mediates PI3P Homeostasis at Endosomal Compartments
This article uses metazachlor, an inhibitor of VLCFA synthesis, to find that VLCFAs are involved in the TGN/MVB distribution of PI3P. This effect is independent from either synthesis of PI3P by PI3-kinase or degradation of PI(3,5)P2 into PI3P by the SUPPRESSOR OF ACTIN1 (SAC1) phosphatase. Results suggest that PI3P might be transferable from TGN to MVBs and that VLCFAs act in this process.
Date:
August 6, 2021
Creator:
Ito, Yoko; Esnay, Nicolas; Fougère, Louise; Platre, Matthieu Pierre; Cordelières, Fabrice; Jaillais, Yvon et al.
Object Type:
Article
System:
The UNT Digital Library