Rapid Responses to Abiotic Stress: Priming the Landscape for the Signal Transduction Network (open access)

Rapid Responses to Abiotic Stress: Priming the Landscape for the Signal Transduction Network

This article proposes that the integration of these signals is mediated through pulses of gene expression that are coordinated through out the plant in a systemic manner by the ROS/Ca⁺² waves.
Date: November 3, 2018
Creator: Kollist, Hannes; Zandalinas, Sara I.; Sengupta, Soham; Nuhkat, Maris; Kangasjärvi, Jaakko & Mittler, Ron
Object Type: Article
System: The UNT Digital Library
Peptide signaling molecules CLE5 and CLE6 affect Arabidopsis leaf shape downstream of leaf patterning transcription factors and auxin (open access)

Peptide signaling molecules CLE5 and CLE6 affect Arabidopsis leaf shape downstream of leaf patterning transcription factors and auxin

Article describes a role in Arabidopsis leaf development for two members of the CLAVATA3/ESR‐RELATED peptide family, CLE5 and CLE6, which lie adjacent to each other on chromosome 2.
Date: December 20, 2018
Creator: DiGennaro, Peter; Grienenberger, Etienne; Dao, Thai Q.; Jun, Ji Hyung & Fletcher, Jennifer C.
Object Type: Article
System: The UNT Digital Library
Specialized impulse conduction pathway in the alligator heart (open access)

Specialized impulse conduction pathway in the alligator heart

Article describes a study which examines the conduction system in crocodiles (Alligator mississippiensis), the only ectothermic vertebrates with a full ventricular septum.
Date: March 22, 2018
Creator: Jensen, Bjarke; Boukens, Bastiaan J; Crossley, Dane A., II; Conner, Justin; Mohan, Rajiv A.; van Duijvenboden, Karel et al.
Object Type: Article
System: The UNT Digital Library
A novel benzimidazole derivative, MBIC inhibits tumor growth and promotes apoptosis via activation of ROS-dependent JNK signaling pathway in hepatocellular carcinoma (open access)

A novel benzimidazole derivative, MBIC inhibits tumor growth and promotes apoptosis via activation of ROS-dependent JNK signaling pathway in hepatocellular carcinoma

This study further explores a prior screening program carried out using MTT assay that identified a series of novel benzimidazole derivatives, among which Methyl 2-(5-fluoro-2-hydroxyphenyl)-1H-benzo[d]imidazole-5-carboxylate (MBIC) showed highest anticancer efficacy compared to that of chemotherapeutic agent, cisplatin. In this article, the authors find that MBIC inhibited cell viability in different hepatocellular carcinoma (HCC) cell lines without exerting significant cytotoxic effects on normal liver cells. The results of this study demonstrate that MBIC may inhibit cell proliferation via ROS-mediated activation of the JNK signaling cascade in HCC cells.
Date: January 12, 2017
Creator: Dai, Xiaoyun; Wang, Ling Zhi; Deivasigamni, Amudha; Looi, Chung Yeng; Karthikeyan, Chandrabose; Trivedi, Piyush et al.
Object Type: Article
System: The UNT Digital Library
Simultaneous electrophysiological and morphological assessment of functional damage to neural networks in vitro after 30–300 g impacts (open access)

Simultaneous electrophysiological and morphological assessment of functional damage to neural networks in vitro after 30–300 g impacts

Article describes studying aiming to investigate and quantify network activity changes after simulated concussions in vitro and therewith develop a platform for simultaneous and direct observations of morphological and electrophysiological changes in neural networks.
Date: October 18, 2019
Creator: Rogers, Edmond A. & Gross, Guenter W.
Object Type: Article
System: The UNT Digital Library
The genome of jojoba (Simmondsia chinensis): A taxonomically isolated species that directs wax ester accumulation in its seeds (open access)

The genome of jojoba (Simmondsia chinensis): A taxonomically isolated species that directs wax ester accumulation in its seeds

Article describes the high-quality, 887-Mb genome of jojoba assembled into 26 chromosomes with 23,490 protein-coding genes.
Date: March 11, 2020
Creator: Sturtevant, Drew; Lu, Shaoping; Zhou, Zhi-Wei; Shen, Yin; Wang, Shuo; Song, Jia-Ming et al.
Object Type: Article
System: The UNT Digital Library
Prioritizing riparian corridors for ecosystem restoration in urbanizing watersheds (open access)

Prioritizing riparian corridors for ecosystem restoration in urbanizing watersheds

This article explores restoration, rather than protection, being the basis for developing a watershed level strategy for improving water quality in urbanizing watersheds.This study uses a geographical information system (GIS) approach that utilizes riparian characteristics extracted from 40-meter wide corridors centered on streams and rivers. The model was applied to 90 sub-watersheds in the watershed of an important drinking water reservoir in north central Texas, USA.
Date: February 4, 2020
Creator: Atkinson, Samuel F. & Lake, Matthew C.
Object Type: Article
System: The UNT Digital Library
A Small Compound Targeting Prohibitin with Potential Interest for Cognitive Deficit Rescue in Aging mice and Tau Pathology Treatment (open access)

A Small Compound Targeting Prohibitin with Potential Interest for Cognitive Deficit Rescue in Aging mice and Tau Pathology Treatment

Article describes study analyzing the effects of a new purine derivative drug, PDD005, in attenuating mechanisms involved in the pathogenesis of neurodegenerative diseases, using both in vivo and in vitro models.
Date: January 24, 2020
Creator: Guyot, Anne-Cécile; Leuxe, Charlotte; Disdier, Clémence; Oumata, Nassima; Costa, Narciso; Le Roux, Gwenaëlle et al.
Object Type: Article
System: The UNT Digital Library
Generating pathogen- / pest-resistant non-GMO cotton through targeted genome editing of oxylipin signaling pathways (open access)

Generating pathogen- / pest-resistant non-GMO cotton through targeted genome editing of oxylipin signaling pathways

Data management plan for the research grant "Generating pathogen- / pest-resistant non-GMO cotton through targeted genome editing of oxylipin signaling pathways."
Date: 2021-01-15/2024-01-14
Creator: Ayre, Brian G.; McGarry, Roisin C. & Shah, Jyoti
Object Type: Text
System: The UNT Digital Library
LLELA Quail Program: Quail in the Park Cities? Restoring a functional quail population to a small rangeland system in the Dallas Metroplex (open access)

LLELA Quail Program: Quail in the Park Cities? Restoring a functional quail population to a small rangeland system in the Dallas Metroplex

Data management plan for the grant, "LLELA Quail Program: Quail in the Park Cities? Restoring a functional quail population to a small rangeland system in the Dallas Metroplex."
Date: 2021-10-01/2022-09-30
Creator: Gregory, Andrew
Object Type: Text
System: The UNT Digital Library
High degree of non-genetic phenotypic variation in the vascular system of crayfish: a discussion of possible causes and implications (open access)

High degree of non-genetic phenotypic variation in the vascular system of crayfish: a discussion of possible causes and implications

This article studies the hemolymph vascular system (HVS) in two cambarid crayfishes, i.e. the Marbled Crayfish, Procambarus virginalis Lyko, 2017 and the Spiny Cheek Crayfish, Faxonius limosus (Rafinesque, 1817) in regard to areas of non-genetic phenotypic variation.
Date: August 12, 2021
Creator: Scholz, Stephan; Göpel, Torben; Richter, Stefan & Wirkner, Christian S.
Object Type: Article
System: The UNT Digital Library
Magnesium and Fibromyalgia: A Literature Review (open access)

Magnesium and Fibromyalgia: A Literature Review

This article investigates if the widespread use of magnesium in fibromyalgia is supported by evidence in the literature. This review provides a layout of the studies examining the correlation between body magnesium levels and fibromyalgia and elaborates on the trials testing the effectiveness of magnesium in treating different clinical parameters of fibromyalgia.
Date: August 14, 2021
Creator: Boulis, Michael; Boulis, Mary & Clauw, Daniel
Object Type: Article
System: The UNT Digital Library
Developmental Physiology: Grand Challenges (open access)

Developmental Physiology: Grand Challenges

Article indicating directions in which the field of Developmental Physiology might move. It suggests three categories of challenges: demonstrating broad relevance, promoting conceptual advances, and improving experimental approaches.
Date: June 10, 2021
Creator: Burggren, Warren W.
Object Type: Article
System: The UNT Digital Library
Phylogenetic Occurrence of the Phenylpropanoid Pathway and Lignin Biosynthesis in Plants (open access)

Phylogenetic Occurrence of the Phenylpropanoid Pathway and Lignin Biosynthesis in Plants

This article is a review summarizing recent progress in defining the lignin biosynthetic pathway in lycophytes, monilophytes, gymnosperms, and angiosperms. This review provides new insights into the genetic engineering of the lignin biosynthetic pathway to overcome biomass recalcitrance in bioenergy crops.
Date: August 17, 2021
Creator: Yao, Tao; Feng, Kai; Xie, Meng; Barros, Jaime; Tschaplinski, Timothy J.; Tuskan, Gerald et al.
Object Type: Article
System: The UNT Digital Library
Regulators of von Willebrand Factor Levels (open access)

Regulators of von Willebrand Factor Levels

Data management plan for the grant "Regulators of von Willebrand Factor Levels." Von Willebrand Disease is the most prevalent bleeding disease. In one of the types called type 1 von Willebrand Disease, the disease-causing genes are not known. Using zebrafish as a model, this project proposes to identify genes that cause the disease by crippling the genes by knockdown methods, and such identification may lead to not only the identification of mutations in the corresponding human genes but also to a better diagnosis.
Date: 2021-08-01/2024-07-31
Creator: Jagadeeswaran, Pudur
Object Type: Text
System: The UNT Digital Library
Developmental thyroid disruption causes long-term impacts on immune cell function and transcriptional responses to pathogen in a small fish model (open access)

Developmental thyroid disruption causes long-term impacts on immune cell function and transcriptional responses to pathogen in a small fish model

This article explores the connection between thyroid hormones (THs) and immune systems in fish. This article is noteworthy as disruption of the thyroid system during development, which can occur in response to chemicals present in the environment, may have lasting effects on immune function in adulthood for fish.
Date: July 14, 2021
Creator: Thornton Hampton, Leah M.; Finch, Miranda G.; Martyniuk, Christopher J.; Venables, Barney J. & Jeffries, Marlo K. Sellin
Object Type: Article
System: The UNT Digital Library
Exposure to diesel exhaust particles results in altered lung microbial profiles, associated with increased reactive oxygen species/reactive nitrogen species and inflammation, in C57Bl/6 wildtype mice on a high-fat diet (open access)

Exposure to diesel exhaust particles results in altered lung microbial profiles, associated with increased reactive oxygen species/reactive nitrogen species and inflammation, in C57Bl/6 wildtype mice on a high-fat diet

Article investigating if the exposure to diesel exhaust particles (DEP) can alter commensal lung microbiota, thereby promoting alterations in the lung’s immune and inflammatory responses. This article also explores if diet contributes to the alteration of the commensal lung microbiome.
Date: January 8, 2021
Creator: Daniel, Sarah; Phillippi, Danielle; Schneider, Leah J.; Nguyen, Kayla N.; Mirpuri, Julie & Lund, Amie K.
Object Type: Article
System: The UNT Digital Library
Knockdown screening of chromatin binding and regulatory proteins in zebrafish identified Suz12b as a regulator of tfpia and an antithrombotic drug target (open access)

Knockdown screening of chromatin binding and regulatory proteins in zebrafish identified Suz12b as a regulator of tfpia and an antithrombotic drug target

Article identifying novel epigenetic regulators for tfpia and exploiting this information to discover a drug that enhances tfpia mRNA levels and prolongation of TTO. This discovery provides the basis for testing whether UNC6852 could be used as an antithrombotic drug.
Date: July 27, 2021
Creator: Raman, Revathi; Fallatah, Weam; Al Qaryoute, Ayah; Dhinoja, Sanchi & Jagadeeswaran, Pudur
Object Type: Article
System: The UNT Digital Library
Sphingolipids mediate polar sorting of PIN2 through phosphoinositide consumption at the trans-Golgi network (open access)

Sphingolipids mediate polar sorting of PIN2 through phosphoinositide consumption at the trans-Golgi network

Article discovering a mechanism for how sphingolipids mediate phosphoinositide homeostasis at the TGN in plant cells. The data presented identifies a mode of action of sphingolipids in lipid interplay at the TGN during protein sorting.
Date: July 13, 2021
Creator: Ito, Yoko; Esnay, Nicolas; Platre, Matthieu Pierre; Wattelet-Boyer, Valérie; Noack, Lise C.; Fougère, Louise et al.
Object Type: Article
System: The UNT Digital Library
Dual activity of anthocyanidin reductase supports the dominant plant proanthocyanidin extension unit pathway (open access)

Dual activity of anthocyanidin reductase supports the dominant plant proanthocyanidin extension unit pathway

This article presents research on genetic and biochemical analyses that shows ANR has dual activity and is involved not only in the production of (−)-epicatechin starter units but also in the formation of 2,3-cis-leucocyanidin to serve as (−)-epicatechin extension units. The results find that differences in the product specificities of ANRs account for the presence/absence of PA polymerization and the compositions of PAs across plant species
Date: May 14, 2021
Creator: Jun, Ji Hyung; Lu, Nan; Docampo-Palacios, Maite; Wang, Xiaoqiang & Dixon, R. A.
Object Type: Article
System: The UNT Digital Library
In silico guided structural and functional analysis of genes with potential involvement in resistance to coffee leaf rust: A functional marker based approach (open access)

In silico guided structural and functional analysis of genes with potential involvement in resistance to coffee leaf rust: A functional marker based approach

Article presents novel insights into the molecular nature of the SH genes, thereby opening new avenues for coffee rust resistance molecular breeding.
Date: July 8, 2020
Creator: Ferreira, Svio Siqueira; Barka, Geleta Dugassa; Caixeta, Eveline Teixeira & Zambolim, Larcio
Object Type: Article
System: The UNT Digital Library
Lipophilic signals lead to organ-specific gene expression changes in Arabidopsis seedlings (open access)

Lipophilic signals lead to organ-specific gene expression changes in Arabidopsis seedlings

Article presents a study where whole transcriptome sequencing (RNA-seq) and differential expression analysis were used to identify early (1–3 hr) transcriptional changes induced by the exogenous treatment of NAE 18:2 and NAE 18:3 in cotyledons, roots, and seedlings.
Date: July 15, 2020
Creator: Cannon, Ashley E.; Yan, Chengshi; Burks, David J.; Rao, Xiaolan; Azad, Rajeev K. & Chapman, Kent Dean
Object Type: Article
System: The UNT Digital Library
Insertional mutagenesis of Brachypodium distachyon using the Tnt1 retrotransposable element (open access)

Insertional mutagenesis of Brachypodium distachyon using the Tnt1 retrotransposable element

Article is a study exploring the possibility of using the tobacco retrotransposon Tnt1 to create a transposon-based insertion mutant population in B. distachyon.
Date: May 15, 2020
Creator: Serrani-Yarce, Juan C.; Nandety, Raja Sekhar; Gill, Upinder S.; Oh, Sunhee; Lee, Hee-Kyung; Zhang, Xinji et al.
Object Type: Article
System: The UNT Digital Library
A Simple Method for Measuring Apoplast Hydration and Collecting Apoplast Contents (open access)

A Simple Method for Measuring Apoplast Hydration and Collecting Apoplast Contents

This article describes a refined method optimized for maize (Zea mays) seedling leaves, which not only provides a simple procedure for obtaining apoplast fluid, but also allows direct calculation of apoplast hydration at the time of harvest for every sample.
Date: March 1, 2019
Creator: Gentzel, Irene; Giese, Laura; Zhao, Wanying; Alonso, Ana Paula & Mackey, David
Object Type: Article
System: The UNT Digital Library