Deciphering pathogenicity and antibiotic resistance islands in methicillin-resistant Staphylococcus aureus genomes (open access)

Deciphering pathogenicity and antibiotic resistance islands in methicillin-resistant Staphylococcus aureus genomes

This article explores the use of an information-entropy-based gene clustering method for genomic island detection in MRSA.
Date: November 16, 2017
Creator: Jani, Mehul; Sengupta, Soham; Hu, Kelsey & Azad, Rajeev K.
Object Type: Article
System: The UNT Digital Library
The future of legume genetic data resources: Challenges, opportunities, and priorities (open access)

The future of legume genetic data resources: Challenges, opportunities, and priorities

This article is a commentary on the future of legume genetic data resources and summarizes the workshop held in March of 2019 by the Legume Genomic Data Working Group that addressed questions of data resources and priorities for legumes.
Date: August 5, 2019
Creator: Legume Genomic Data Working Group
Object Type: Article
System: The UNT Digital Library
In situ cardiac performance of Atlantic cod (Gadus morhua) at cold temperatures: long-term acclimation, acute thermal challenge and the role of adrenaline (open access)

In situ cardiac performance of Atlantic cod (Gadus morhua) at cold temperatures: long-term acclimation, acute thermal challenge and the role of adrenaline

This article measures the cardiac performance of Newfoundland Atlantic cod (Gadus morhua). The results: (1) show that maximum performance of the isolated cod heart is not compromised by exposure to cold temperatures; and (2) support data from other studies, which show that, in contrast to salmonids, cod cardiac performance/myocardial contractility is not dependent upon humoral adrenergic stimulation.
Date: November 15, 2012
Creator: Lurman, Glenn J. & Petersen, L. H.
Object Type: Article
System: The UNT Digital Library
Xenopus and the art of oxygen maintenance (open access)

Xenopus and the art of oxygen maintenance

This column article discusses the impact of Robert Boutillier and Graham Shelton's 1986 Journal of Experimental Biology paper "Gas exchange, storage and transport in voluntarily diving Xenopus laevis."
Date: November 15, 2017
Creator: Tattersall, Glenn & Burggren, Warren W.
Object Type: Article
System: The UNT Digital Library
Embryonic developmental oxygen preconditions cardiovascular functional response to acute hypoxic exposure and maximal β-adrenergic stimulation of anesthetized juvenile American alligators (Alligator mississippiensis) (open access)

Embryonic developmental oxygen preconditions cardiovascular functional response to acute hypoxic exposure and maximal β-adrenergic stimulation of anesthetized juvenile American alligators (Alligator mississippiensis)

Article investigating the effect of embryonic hypoxia on the cardiovascular phenotype of 4-year-old American alligators (Alligator mississippiensis). The findings indicate that embryonic hypoxia in crocodilians alters the cardiovascular phenotype, changing the juvenile response to acute hypoxia and β-adrenergic stimulation.
Date: January 26, 2018
Creator: Smith, Brandt R.; Crossley, Janna; Elsey, Ruth M.; Hicks, James W. & Crossley, Dane A., II
Object Type: Article
System: The UNT Digital Library
Isorhamnetin Inhibits Proliferation and Invasion and Induces Apoptosis through the Modulation of Peroxisome Proliferator-activated Receptor γ Activation Pathway in Gastric Cancer (open access)

Isorhamnetin Inhibits Proliferation and Invasion and Induces Apoptosis through the Modulation of Peroxisome Proliferator-activated Receptor γ Activation Pathway in Gastric Cancer

Article investigating the potential effects of isorhamnetin (IH), a 3′-O-methylated metabolite of quercetin on the peroxisome proliferator-activated receptor γ (PPAR-γ) signaling cascade using proteomics technology platform, GC cell lines, and xenograft mice model. The study y proposes a novel agent for gastric cancer treatment.
Date: November 2, 2012
Creator: Ramachandran, Lalitha; Manu, Kanjoormana Aryan; Shanmugam, Muthu K.; Li, Feng; Siveen, Kodappully Sivaraman; Vali, Shireen et al.
Object Type: Article
System: The UNT Digital Library
Effect of increased embryonic temperature during developmental windows on survival, morphology and oxygen consumption of rainbow trout (Oncorhynchus mykiss) (open access)

Effect of increased embryonic temperature during developmental windows on survival, morphology and oxygen consumption of rainbow trout (Oncorhynchus mykiss)

This article applies a developmental 3-dimensional critical window experimental design for a vertebrate, using time, temperature, and phenotypic response (i.e., variables measured). To assess thermal effects on fish development, the authors examined trout hatchling phenotypes following rearing in constant temperatures (5, 10, 15 and 17.5 °C) and following exposure to increased temperature above 5 °C during specific developmental windows.
Date: November 2, 2020
Creator: Melendez, Christopher L. & Mueller, Casey A.
Object Type: Article
System: The UNT Digital Library
CaMV35S promoter – A plant biology and biotechnology workhorse in the era of synthetic biology (open access)

CaMV35S promoter – A plant biology and biotechnology workhorse in the era of synthetic biology

This review article calls for establishing the CaMV 35S promoter as a quantitative reference standard for transcription activity in plants.
Date: November 18, 2020
Creator: Amack, Stephanie C. & Antunes, Mauricio S.
Object Type: Article
System: The UNT Digital Library
Editorial: Biofuels and Bioenergy (open access)

Editorial: Biofuels and Bioenergy

Editorial on the research topic of biofuels and bioenergy.
Date: November 30, 2020
Creator: Barros-Rios, Jaime; Zhang, Jin & Lu, Mengzhu
Object Type: Article
System: The UNT Digital Library
Muconic acid production from methane using rationally-engineered methanotrophic biocatalysts (open access)

Muconic acid production from methane using rationally-engineered methanotrophic biocatalysts

Article demonstrates bioconversion of methane to muconic acid, a dicarboxylic acid that can be upgraded to an array of platform chemicals, by three gammaproteobacterial methanotrophs.
Date: November 25, 2019
Creator: Henard, Calvin A.; Akberdin, Ilya R.; Kalyuzhnaya, Marina G. & Guarnieri, Michael T.
Object Type: Article
System: The UNT Digital Library
Prebiotic/probiotic supplementation resulted in reduced visceral fat and mRNA expression associated with adipose tissue inflammation, systemic inflammation, and chronic disease risk (open access)

Prebiotic/probiotic supplementation resulted in reduced visceral fat and mRNA expression associated with adipose tissue inflammation, systemic inflammation, and chronic disease risk

Article describes how prebiotic/probiotic supplementation represents a viable option for addressing elevated systemic inflammation and chronic disease risk in overweight individuals. The key findings support that 90-day prebiotic/probiotic supplementation may be associated with reduced adipose tissue inflammation, reduced systemic inflammation, and reduced chronic disease risk.
Date: November 28, 2022
Creator: McFarlin, Brian K.; Tanner, Elizabeth A.; Hill, David W. & Vingren, Jakob L.
Object Type: Article
System: The UNT Digital Library
The protein conformational basis of isoflavone biosynthesis (open access)

The protein conformational basis of isoflavone biosynthesis

Authors of the article assert that isoflavonoids play important roles in plant defense and also exhibit a range of mammalian health-promoting activities. They emphasize that understanding the structural basis of isoflavone biosynthesis will facilitate the engineering of new bioactive isoflavonoids.
Date: November 15, 2022
Creator: Wang, Xiaoqiang; Pan, Haiyun; Sagurthi, Someswar; Paris, Vincent; Zhuo, Chunliu & Dixon, R. A.
Object Type: Article
System: The UNT Digital Library
Transcriptomic profiling of miR-203a inhibitor and miR-34b-injected zebrafish (Danio rerio) validates oil-induced neurological, cardiovascular and eye toxicity response pathways (open access)

Transcriptomic profiling of miR-203a inhibitor and miR-34b-injected zebrafish (Danio rerio) validates oil-induced neurological, cardiovascular and eye toxicity response pathways

Article discusses how the global sequencing of microRNA (miRNA; miR) and integration to downstream mRNA expression profiles in early life stages (ELS) of fish following exposure to crude oil determined consistently dysregulated miRNAs regardless of the oil source or fish species. The overlay of differentially expressed miRNAs and mRNAs into in silico software determined that the key roles of these miRNAs were predicted to be involved in cardiovascular, neurological and visually-mediated pathways.
Date: November 21, 2022
Creator: Maguson, Jason T.; Leads, Rachel R.; McGruer, Victoria; Qian, Le; Tanabe, Philip; Roberts, Aaron P. et al.
Object Type: Article
System: The UNT Digital Library
The complexities of proanthocyanidin biosynthesis and its regulation in plants (open access)

The complexities of proanthocyanidin biosynthesis and its regulation in plants

Article describes how proanthocyanidins (PAs) are natural flavan-3-ol polymers that contribute protection to plants under biotic and abiotic stress, benefits to human health, and bitterness and astringency to food products. This review extends the conventional understanding with recent findings that provide new insights to address lingering questions and focus strategies for manipulating PA traits in plants.
Date: November 26, 2022
Creator: Yu, Keji; Song, Yushuang; Lin, Jinxing & Dixon, R. A.
Object Type: Article
System: The UNT Digital Library
Role of ribosomal RNA released from red cells in blood coagulation in zebrafish and humans (open access)

Role of ribosomal RNA released from red cells in blood coagulation in zebrafish and humans

This article identifies that an rRNA released in hemolysis activates clotting in human and zebrafish plasma. Furthermore, it shows that fish Hgfac plays a role in rRNA-mediated activation of coagulation.
Date: November 17, 2021
Creator: Alharbi, Abdulmajeed; Iyer, Neha; Al Qaryoute, Ayah; Raman, Revathi; Burks, David J.; Azad, Rajeev K. et al.
Object Type: Article
System: The UNT Digital Library
Dynamic Changes in Transcriptome and Cell Wall Composition Underlying Brassinosteroid‑Mediated Lignification of Switchgrass Suspension Cells (open access)

Dynamic Changes in Transcriptome and Cell Wall Composition Underlying Brassinosteroid‑Mediated Lignification of Switchgrass Suspension Cells

This article provides an overview of the dynamic compositional changes during brassinosteroid-induced cell wall remodeling, and identifies candidate genes for future plant genetic engineering to overcome cell wall recalcitrance.
Date: August 8, 2017
Creator: Rao, Xiaolan; Shen, Hui; Pattathil, Sivakumar; Hahn, Michael G.; Gelineo-Albersheim, Ivana; Mohnen, Debra et al.
Object Type: Article
System: The UNT Digital Library
Rapid Responses to Abiotic Stress: Priming the Landscape for the Signal Transduction Network (open access)

Rapid Responses to Abiotic Stress: Priming the Landscape for the Signal Transduction Network

This article proposes that the integration of these signals is mediated through pulses of gene expression that are coordinated through out the plant in a systemic manner by the ROS/Ca⁺² waves.
Date: November 3, 2018
Creator: Kollist, Hannes; Zandalinas, Sara I.; Sengupta, Soham; Nuhkat, Maris; Kangasjärvi, Jaakko & Mittler, Ron
Object Type: Article
System: The UNT Digital Library
RNaseH-mediated simultaneous piggyback knockdown of multiple genes in adult zebrafish (open access)

RNaseH-mediated simultaneous piggyback knockdown of multiple genes in adult zebrafish

This article tests if it is possible to piggyback more than one antisense deoxyoligonucleotide (dO) with one vivo morpholino (VMO). The authors previously developed a piggyback knockdown method that was used to knockdown genes in adult zebrafish. In this article, the authors develop a method to knockdown three genes at one time, and by increasing the concentration of VMO by twofold, could knockdown six genes simultaneously. These multiple gene knockdowns will not only increase the efficiency of the method in whole genome-wide knockdowns but will also be useful to study multifactorial disorders.
Date: November 19, 2020
Creator: Raman, Revathi; Ryon, Mia & Jagadeeswaran, Pudur
Object Type: Article
System: The UNT Digital Library
Immunized Plants: An Answer to Global Hunger captions transcript

Immunized Plants: An Answer to Global Hunger

Video from the Fall 2018 3 Minute Thesis (3MT®) Final Competition. In this video, Devasantosh Mohanty presents his research methods, findings, and its significance in non-technical language.
Date: November 17, 2018
Creator: Mohanty, Devasantosh
Object Type: Video
System: The UNT Digital Library
Diabetes Treatment with Sunshine captions transcript

Diabetes Treatment with Sunshine

Video from the Fall 2018 3 Minute Thesis (3MT®) Final Competition. In this video, Sujata Argawal presents her research methods, findings, and its significance in non-technical language.
Date: November 17, 2018
Creator: Argawal, Sujata
Object Type: Video
System: The UNT Digital Library
Reconstructing horizontal gene flow network to understand prokaryotic evolution (open access)

Reconstructing horizontal gene flow network to understand prokaryotic evolution

Article says that horizontal gene transfer (HGT) is a major source of phenotypic innovation and a mechanism of niche adaptation in prokaryotes. Methods for detecting HGT can be classified into phylogenetic-based and parametric or composition-based approaches, so authors exploited the complementary strengths of both the approaches to construct a high confidence horizontal gene flow network. The scale-free horizontal gene flow network presented here provides new insights into modes of transfer for the exchange of genetic information and also illuminates differential gene flow across phyla.
Date: November 30, 2022
Creator: Sungupta, Soham & Azad, Rajeev K.
Object Type: Article
System: The UNT Digital Library
A lipidomics platform to analyze the fatty acid compositions of non-polar and polar lipid molecular species from plant tissues: Examples from developing seeds and seedlings of pennycress (Thlaspi arvense) (open access)

A lipidomics platform to analyze the fatty acid compositions of non-polar and polar lipid molecular species from plant tissues: Examples from developing seeds and seedlings of pennycress (Thlaspi arvense)

Article describes a stepwise targeted lipidomics approach to characterize the polar and non-polar lipid classes using complementary LC-MS methods. This lipidomics workflow was applied to developing, mature, and germinated pennycress seeds/seedlings and found unexpected changes among several lipid molecular species.
Date: November 9, 2022
Creator: Romsdahl, Trevor B.; Cocuron, Jean-Christophe; Pearson, Mackenzie J.; Alonso, Ana Paula & Chapman, Kent Dean
Object Type: Article
System: The UNT Digital Library
Manipulating plasma thyroid hormone levels alters development of endothermy and ventilation in nestling red-winged blackbirds (open access)

Manipulating plasma thyroid hormone levels alters development of endothermy and ventilation in nestling red-winged blackbirds

Authors of the article propose that thyroid hormones play an important role in regulating development of endothermy during the nestling period in altricial birds. Their data suggests plasma thyroid hormone levels play an active role in the systemic development of endothermic capacity and the development of ventilatory control.
Date: November 29, 2022
Creator: Sirsat, Tushar S.; Sirsat, Sarah K. G.; Price, Edwan R.; Pineda, Megan & Dzialowski, Edward M. (Edward Michael)
Object Type: Article
System: The UNT Digital Library
Lipid Droplets: Packing Hydrophobic Molecules Within the Aqueous Cytoplasm (open access)

Lipid Droplets: Packing Hydrophobic Molecules Within the Aqueous Cytoplasm

Article discusses how lipid droplets, also known as oil bodies or lipid bodies, are plant organelles that compartmentalize neutral lipids as a hydrophobic matrix covered by proteins embedded in a phospholipid monolayer. The authors review the growing body of knowledge about lipid droplets in plant cells, describe the evolutionary similarity and divergence in their associated subcellular machinery, and point to gaps that deserve future attention.
Date: November 22, 2022
Creator: Guzha, Athanas; Whitehead, Payton; Ischebeck, Till & Chapman, Kent Dean
Object Type: Article
System: The UNT Digital Library