A practical guide for assessing respiratory burst and phagocytic cell activity in the fathead minnow, an emerging model for immunotoxicity (open access)

A practical guide for assessing respiratory burst and phagocytic cell activity in the fathead minnow, an emerging model for immunotoxicity

Article is a study with the goal of optimizing and validating the use of a colorimetric plate-based respiratory burst and fluorometric plate-based phagocytic cell activity assays for use with kidney cells from the fathead minnow (Pimephales promelas), an emerging immunotoxicity model.
Date: July 18, 2020
Creator: Thornton Hampton, Leah M.; Venables, Barney J. & Jeffries, Marlo K. Sellin
System: The UNT Digital Library
Rapid embryonic accretion of docosahexaenoic acid (DHA) in the brain of an altricial bird with an aquatic-based maternal diet (open access)

Rapid embryonic accretion of docosahexaenoic acid (DHA) in the brain of an altricial bird with an aquatic-based maternal diet

This article communicates the results of a study conducted on red-winged blackbirds where brain phospholipid composition during development was measured and diet was manipulated. The dietary study confirmed that nestling brains are sensitive to fatty acid supply. The findings of this article suggest that Red-winged blackbirds may be able to advance cognitive development relative to other altricial species owing to their aquatic maternal diet.
Date: July 23, 2018
Creator: Price, Edwin R.; Sirsat, Sarah K. G.; Sirsat, Tushar S.; Venables, Barney J. & Dzialowski, Edward M. (Edward Michael)
System: The UNT Digital Library
Remodeling the epigenome and (epi)cytoskeleton: a new paradigm for co-regulation by methylation (open access)

Remodeling the epigenome and (epi)cytoskeleton: a new paradigm for co-regulation by methylation

This article is a commentary on coordinated use of methyl marks to remodel both the epigenome and the (epi)cytoskeleton, which opens the possibility for integrated regulation (referred to as ‘epiregulation’) of other higher-level functions, such as muscle contraction or learning and memory, and could even have evolutionary implications.
Date: July 3, 2020
Creator: Walker, Cheryl & Burggren, Warren W.
System: The UNT Digital Library
Scaling of axial muscle architecture in juvenile Alligator mississippiensis reveals an enhanced performance capacity of accessory breathing mechanisms (open access)

Scaling of axial muscle architecture in juvenile Alligator mississippiensis reveals an enhanced performance capacity of accessory breathing mechanisms

Article describing the anatomy of the trunk muscles, their properties that determine muscle performance (mass, length and physiological cross-sectional area [PCSA]) and investigating their scaling in juvenile Alligator mississippiensis spanning an order of magnitude in body mass (359 g–5.5 kg). Findings support existing anecdotal evidence that crocodilians shift their breathing mechanics as they increase in size.
Date: July 23, 2021
Creator: Rose, Kayleigh A. R.; Tickle, Peter G.; Elsey, Ruth M.; Sellers, William I.; Crossley, Dane A., II & Codd, Jonathan R.
System: The UNT Digital Library
Temperature-sensitive Post-translational Regulation of Plant Omega-3 Fatty-acid Desaturases Is Mediated by the Endoplasmic Reticulum-associated Degradation Pathway (open access)

Temperature-sensitive Post-translational Regulation of Plant Omega-3 Fatty-acid Desaturases Is Mediated by the Endoplasmic Reticulum-associated Degradation Pathway

Article expressing two closely related plant FAD3 genes in yeast cells and found that their enzymes produced significantly different amounts of omega-3 fatty acids and that these differences correlated to differences in rates of protein turnover. The findings indicate that Fad3 protein abundance is regulated by a combination of cis-acting degradation signals and the ubiquitin-proteasome pathway and that modulation of Fad3 protein amounts in response to temperature may represent one mechanism of homeoviscous adaptation in plants.
Date: July 9, 2010
Creator: O'Quin, Jami B.; Bourassa, Linda; Zhang, Daiyuan; Shockey, Jay M.; Gidda, Satinder K.; Fosnot, Spencer et al.
System: The UNT Digital Library
Altitudinal gradients in Magellanic sub-Antarctic lagoons: the effect of elevation on freshwater macroinvertebrate diversity and distribution (open access)

Altitudinal gradients in Magellanic sub-Antarctic lagoons: the effect of elevation on freshwater macroinvertebrate diversity and distribution

In this article, freshwater macroinvertebrate diversity associated with lakes and ponds along the altitudinal gradient of a Magellanic sub-Antarctic watershed are assessed. A monotonic decline in species richness was observed with increasing elevation, with simpler and more even community composition at higher altitude. This pattern differs from the mid-peak trend found in streams of the same watershed. Functional feeding group structure also diminished with increasing elevation.
Date: July 29, 2019
Creator: Rendoll Cárcamo, Javier; Contador, Tamara; Gañán, Melisa; Pérez Troncoso, Carolina; Maldonado Márquez, Alan; Convey, Peter et al.
System: The UNT Digital Library
Whole-genome survey reveals extensive variation in genetic diversity and inbreeding levels among peregrine falcon subspecies (open access)

Whole-genome survey reveals extensive variation in genetic diversity and inbreeding levels among peregrine falcon subspecies

Article describes how, in efforts to prevent extinction, resource managers are often tasked with increasing genetic diversity in a population of concern to prevent inbreeding depression or improve adaptive potential in a changing environment. The authors used whole-genome resequencing to generate over two million single nucleotide polymorphisms (SNPs) from multiple individuals of all peregrine falcon subspecies.
Date: July 20, 2023
Creator: Johnson, Jeff A.; Athrey, Giridhar; Anderson, Clifford M.; Bell, Douglas A.; Dixon, Andrew; Kumazawa, Yoshinori et al.
System: The UNT Digital Library
Comparing Methods of Defining Priority Areas for Greater Sage-Grouse (open access)

Comparing Methods of Defining Priority Areas for Greater Sage-Grouse

Article comparing priority areas for wildlife species using different methods and data types. The authors used resource selection function (RSF) models to predict high priority areas and compared this to priority areas developed using two alternative methods: (1) modified conservation buffer, and (2) utilization distribution (UD) models.
Date: July 7, 2022
Creator: Parsons, Lindsey; Jenks, Jonathan; Runia, Travis & Gregory, Andrew
System: The UNT Digital Library
Genome Sequences of Five Streptomyces Bacteriophages Forming Cluster BG (open access)

Genome Sequences of Five Streptomyces Bacteriophages Forming Cluster BG

This article discusses the isolation of five novel phages, which were used to established the cluster BF, using Streptomyces griseus subsp. griseus strain ATcC 10137 as the host.
Date: July 13, 2017
Creator: Donegan-Quick, Richard; Gibbs, Zane A.; Amaku, Patricia O.; Bernal, Joshua T.; Boyd, Dana A. M.; Burr, Angela R. et al.
System: The UNT Digital Library
Effective Mechanisms for Improving Seed Oil Production in Pennycress (Thlaspi arvense L.) Highlighted by Integration of Comparative Metabolomics and Transcriptomics (open access)

Effective Mechanisms for Improving Seed Oil Production in Pennycress (Thlaspi arvense L.) Highlighted by Integration of Comparative Metabolomics and Transcriptomics

Article presents comparative biomass, metabolomic, and transcriptomic analyses between a high oil accession (HO) and low oil accession (LO) of pennycress to assess potential factors required to optimize oil content.
Date: July 14, 2022
Creator: Johnston, Christopher; García Navarrete, Tatiana; Ortiz, Emmanuel; Romsdahl, Trevor B.; Guzha, Athanas; Chapman, Kent Dean et al.
System: The UNT Digital Library
Heart Performance Determination by Visualization in Larval Fishes: Influence of Alternative Models for Heart Shape and Volume (open access)

Heart Performance Determination by Visualization in Larval Fishes: Influence of Alternative Models for Heart Shape and Volume

This article assesses the validity of three different heart models applied to digital images of complete cardiac cycles in larval mahi-mahi and red drum.
Date: July 4, 2017
Creator: Perrichon, Prescilla; Grosell, Martin & Burggren, Warren W.
System: The UNT Digital Library
Association between CYP2D6 Genotypes and the Risk of Antidepressant Discontinuation, Dosage Modification and the Occurrence of Maternal Depression during Pregnancy (open access)

Association between CYP2D6 Genotypes and the Risk of Antidepressant Discontinuation, Dosage Modification and the Occurrence of Maternal Depression during Pregnancy

This article investigates the association between CYP2D6 genotype and the risk of antidepressant discontinuation, dosage modification, and the occurrence of maternal CYP2D6, Antidepressants, Depression during pregnancy.
Date: July 17, 2017
Creator: Bérard, Anick; Gaedigk, Andrea; Sheehy, Odile; Chambers, Christina; Roth, Mark; Bozzo, Pina et al.
System: The UNT Digital Library
Developmental Transcriptomic Analyses for Mechanistic Insights Into Critical Pathways Involved in Embryogenesis of Pelagic Mahi-Mahi (Coryphaena Hippurus) (open access)

Developmental Transcriptomic Analyses for Mechanistic Insights Into Critical Pathways Involved in Embryogenesis of Pelagic Mahi-Mahi (Coryphaena Hippurus)

This article characterizes the developmental transcriptome of mahi-mahi by means of high throughput sequencing at three critical developmental stages.
Date: July 10, 2017
Creator: Xu, Elvis Genbo; Mager, Edward M.; Grosell, Martin; Stieglitz, John D.; Hazard, E. Starr; Hardiman, Gary et al.
System: The UNT Digital Library
Ectopic Defense Gene Expression Is Associated with Growth Defects in Medicago truncatula Lignin Pathway Mutants (open access)

Ectopic Defense Gene Expression Is Associated with Growth Defects in Medicago truncatula Lignin Pathway Mutants

Article analyzing transposon insertion mutants resulting in independent loss of function of five enzymes of the monolignol pathway, as well as one double mutant, in the model legume Medicago truncatula, to address whether a common mechanism linking lignin modification with perturbations in plant growth and development exists.
Date: July 9, 2019
Creator: Ha, Chan Man; Fine, Dennis; Bhatia, Anil; Rao, Xiaolan; Martin, Madhavi Z.; Engle, Nancy L. et al.
System: The UNT Digital Library
Tailoring seed oil composition in the real world: optimising omega-3 long chain polyunsaturated fatty acid accumulation in transgenic Camelina sativa (open access)

Tailoring seed oil composition in the real world: optimising omega-3 long chain polyunsaturated fatty acid accumulation in transgenic Camelina sativa

This article discusses the further tailoring of the seed oil profile to reduce the omega-6 content, and an evaluation of the performance of such GM plants under field conditions in terms of agronomic performance and the lipidomic profile of seed oil.
Date: July 26, 2017
Creator: Usher, Sarah; Han, Lihua; Haslam, Richard P.; Michaelson, Louise V.; Sturtevant, Drew; Aziz, Mina et al.
System: The UNT Digital Library
Tales of diversity: Genomic and morphological characteristics of forty-six Arthrobacter phages (open access)

Tales of diversity: Genomic and morphological characteristics of forty-six Arthrobacter phages

This article describes the isolation and genomic characterization of 46 phages from environmental samples at various geographic locations in the U.S. infecting a single Arthrobacter sp. strain.
Date: July 17, 2017
Creator: Klyczek, Karen; Bonilla, J. Alfred; Jacobs-Sera, Deborah; Adair, Tamarah; Afram, Patricia; Allen, Katherine G. et al.
System: The UNT Digital Library
Mediterranean Spur-Thighed Tortoises (Testudo graeca) Have Optimal Speeds at Which They Can Minimise the Metabolic Cost of Transport, on a Treadmill (open access)

Mediterranean Spur-Thighed Tortoises (Testudo graeca) Have Optimal Speeds at Which They Can Minimise the Metabolic Cost of Transport, on a Treadmill

Article experimentally quantifies the metabolic cost of transport in Mediterranean spur-thighed tortoises walking on a treadmill while also quantifying the kinematics of their movement. Results found that tortoises move more efficiently than predicted and presents the first data demonstrating a curvilinear cost of transport over their speed range. The authors conclude that tortoises have an optimum speed at which they move to minimise their metabolic cost of locomotion.
Date: July 13, 2022
Creator: Ewart, Heather; Tickle, Peter; Nudds, Robert; Sellers, William; Crossley, Dane A., II & Codd, Jonathan
System: The UNT Digital Library
Developmental thyroid disruption causes long-term impacts on immune cell function and transcriptional responses to pathogen in a small fish model (open access)

Developmental thyroid disruption causes long-term impacts on immune cell function and transcriptional responses to pathogen in a small fish model

This article explores the connection between thyroid hormones (THs) and immune systems in fish. This article is noteworthy as disruption of the thyroid system during development, which can occur in response to chemicals present in the environment, may have lasting effects on immune function in adulthood for fish.
Date: July 14, 2021
Creator: Thornton Hampton, Leah M.; Finch, Miranda G.; Martyniuk, Christopher J.; Venables, Barney J. & Jeffries, Marlo K. Sellin
System: The UNT Digital Library
Knockdown screening of chromatin binding and regulatory proteins in zebrafish identified Suz12b as a regulator of tfpia and an antithrombotic drug target (open access)

Knockdown screening of chromatin binding and regulatory proteins in zebrafish identified Suz12b as a regulator of tfpia and an antithrombotic drug target

Article identifying novel epigenetic regulators for tfpia and exploiting this information to discover a drug that enhances tfpia mRNA levels and prolongation of TTO. This discovery provides the basis for testing whether UNC6852 could be used as an antithrombotic drug.
Date: July 27, 2021
Creator: Raman, Revathi; Fallatah, Weam; Al Qaryoute, Ayah; Dhinoja, Sanchi & Jagadeeswaran, Pudur
System: The UNT Digital Library
Sphingolipids mediate polar sorting of PIN2 through phosphoinositide consumption at the trans-Golgi network (open access)

Sphingolipids mediate polar sorting of PIN2 through phosphoinositide consumption at the trans-Golgi network

Article discovering a mechanism for how sphingolipids mediate phosphoinositide homeostasis at the TGN in plant cells. The data presented identifies a mode of action of sphingolipids in lipid interplay at the TGN during protein sorting.
Date: July 13, 2021
Creator: Ito, Yoko; Esnay, Nicolas; Platre, Matthieu Pierre; Wattelet-Boyer, Valérie; Noack, Lise C.; Fougère, Louise et al.
System: The UNT Digital Library
In silico guided structural and functional analysis of genes with potential involvement in resistance to coffee leaf rust: A functional marker based approach (open access)

In silico guided structural and functional analysis of genes with potential involvement in resistance to coffee leaf rust: A functional marker based approach

Article presents novel insights into the molecular nature of the SH genes, thereby opening new avenues for coffee rust resistance molecular breeding.
Date: July 8, 2020
Creator: Ferreira, Svio Siqueira; Barka, Geleta Dugassa; Caixeta, Eveline Teixeira & Zambolim, Larcio
System: The UNT Digital Library
Lipophilic signals lead to organ-specific gene expression changes in Arabidopsis seedlings (open access)

Lipophilic signals lead to organ-specific gene expression changes in Arabidopsis seedlings

Article presents a study where whole transcriptome sequencing (RNA-seq) and differential expression analysis were used to identify early (1–3 hr) transcriptional changes induced by the exogenous treatment of NAE 18:2 and NAE 18:3 in cotyledons, roots, and seedlings.
Date: July 15, 2020
Creator: Cannon, Ashley E.; Yan, Chengshi; Burks, David J.; Rao, Xiaolan; Azad, Rajeev K. & Chapman, Kent Dean
System: The UNT Digital Library
Leaf Lipid Alterations in Response to Heat Stress of Arabidopsis thaliana (open access)

Leaf Lipid Alterations in Response to Heat Stress of Arabidopsis thaliana

Article measuring lipid levels with mass spectrometry to confirm the previously observed changes in Arabidopsis thaliana leaf lipids under three heat stress regimens. Additionally, in response to heat, increased oxidation of the fatty acyl chains of leaf galactolipids, sulfoquinovosyldiacylglycerols, and phosphatidylglycerols, and incorporation of oxidized acyl chains into acylated monogalactosyldiacylglycerols are shown. The authors also observed increased levels of digalactosylmonoacylglycerols and monogalactosylmonoacylglycerols. The hypothesis that a defect in sterol glycosylation would adversely affect regrowth of plants after a severe heat stress regimen was tested, but differences between wild-type and sterol glycosylation-defective plants were not detected.
Date: July 4, 2020
Creator: Shiva, Sunitha; Samarakoon, Thilani; Lowe, Kaleb A.; Roach, Charles; Vu, Hieu Sy; Colter, Madeline et al.
System: The UNT Digital Library
SEIPIN Isoforms Interact with the Membrane-Tethering Protein VAP27-1 for Lipid Droplet Formation (open access)

SEIPIN Isoforms Interact with the Membrane-Tethering Protein VAP27-1 for Lipid Droplet Formation

Article demonstrating that part of the function of two SEIPIN isoforms in Arabidopsis (Arabidopsis thaliana), AtSEIPIN2 and AtSEIPIN3, may depend on their interaction with the vesicle-associated membrane protein (VAMP)–associated protein (VAP) family member AtVAP27-1. The authors used a combination of biochemical, cell biology, and genetics approaches to show that AtVAP27-1 interacts with the N termini of AtSEIPIN2 and AtSEIPIN3 and likely supports the normal formation of LDs. This insight indicates that the ER membrane tethering machinery in plant cells could play a role with select SEIPIN isoforms in LD biogenesis at the ER, and additional experimental evidence in Saccharomyces cerevisiae supports the possibility that this interaction may be important in other eukaryotic systems.
Date: July 20, 2020
Creator: Greer, Michael Scott; Cai, Yingqi; Gidda, Satinder K.; Esnay, Nicolas; Kretzschmar, Franziska K.; Seay, Damien C. et al.
System: The UNT Digital Library