Effect of MS222 on Hemostasis in Zebrafish (open access)

Effect of MS222 on Hemostasis in Zebrafish

Article studying the effect of MS222 on hemostasis in Zebrafish. The authors performed various assays and find that Hct values, the amount of blood collected, bleeding, and coagulation differ significantly between anesthetized and nonanesthetized fish. These results suggest that blood collected after MS222 anesthesia of zebrafish has altered hemostasis.
Date: May 1, 2019
Creator: Afnan, Deebani; Iyer, Neha; Raman, Revathi & Jagadeeswaran, Pudur
Object Type: Article
System: The UNT Digital Library
Environmental vibrios represent a source of antagonistic compounds that inhibit pathogenic Vibrio cholerae and Vibrio parahaemolyticus strains (open access)

Environmental vibrios represent a source of antagonistic compounds that inhibit pathogenic Vibrio cholerae and Vibrio parahaemolyticus strains

This article predicts that marine-derived bacteria should inhibit Vibrio pathogens and may be a source of unique antibiotic compounds.
Date: March 10, 2017
Creator: Burks, David J.; Norris, Stephen; Kauffman, Kathryn M.; Joy, Abigail; Arevalo, Philip; Azad, Rajeev K. et al.
Object Type: Article
System: The UNT Digital Library
RNA helicase DP103 and TAK1: a new connection in cancer (open access)

RNA helicase DP103 and TAK1: a new connection in cancer

Article on new markers of tumor metastasis. The authors found that expression of DP103 was significantly upregulated in the metastatic basal subtype of breast cancers in 3 independent cohorts. This elevated DP103 expression correlated with metastatic breast cancer gene signatures and was strongly associated with patient survival. This study provides the first evidence that the RNA helicase DEAD-box protein DP103 is an NF-kB target that could form part of a positive feedback loop contributing to DP103- mediated regulation of TAK1 kinase activity on the major NF-kB kinase IKK2, thus implicating DP103 in the maintenance of this oncogenic signaling arm in human cancer.
Date: May 6, 2015
Creator: Shin, Eun Myoung; Osato, Motomi; Kumar, Alan Prem & Tergaonkar, Vinay
Object Type: Article
System: The UNT Digital Library

Developmental phenotypic plasticity helps bridge stochastic weather events associated with climate change

This article posits that the frequently abrupt environmental changes accompanying much longer-term general climate change require consideration of the true nature of environmental change coupled with an expansion of focus to consider developmental phenotypic plasticity.
Date: May 10, 2018
Creator: Burggren, Warren W.
Object Type: Article
System: The UNT Digital Library
Function of Conserved Residues of Human Glutathione Synthetase: Implications for the ATP-Grasp Enzymes (open access)

Function of Conserved Residues of Human Glutathione Synthetase: Implications for the ATP-Grasp Enzymes

Article examining the mechanism of Glutathione synthetase, an enzyme that belongs to the glutathione synthetase ATP-binding domain-like superfamily. A variety of structural alignment methods were applied and four highly conserved residues of human glutathione synthetase (Glu-144, Asn-146, Lys-305, and Lys-364) were identified in the binding site. The function of these was studied by experimental and computational site-directed mutagenesis.
Date: May 21, 2004
Creator: Dinescu, Adriana; Cundari, Thomas R., 1964-; Bhansali, Vikas S.; Luo, Jia-Li & Anderson, Mary E.
Object Type: Article
System: The UNT Digital Library
Evaluation of Threshold Selection Methods for Adaptive Kernel Density Estimation in Disease Mapping (open access)

Evaluation of Threshold Selection Methods for Adaptive Kernel Density Estimation in Disease Mapping

This article assesses the relative performance of threshold selection methods in terms of resolution and reliability for disease mapping.
Date: May 8, 2018
Creator: Ruckthongsook, Warangkana; Tiwari, Chetan; Oppong, Joseph R. & Natesan, Prathiba
Object Type: Article
System: The UNT Digital Library
Noncatalytic chalcone isomerase-fold proteins in Humulus lupulus are auxiliary components in prenylated flavonoid biosynthesis (open access)

Noncatalytic chalcone isomerase-fold proteins in Humulus lupulus are auxiliary components in prenylated flavonoid biosynthesis

This article characterizes two noncatalytic chalcone isomerase (CHI)-like proteins using engineered yeast harboring all genes required for demethylxanthohumol (DMX) production.
Date: February 6, 2018
Creator: Ban, Zhaonan; Qin, Hao; Mitchell, Andrew J.; Liu, Baoxiu; Zhang, Fengxia; Weng, Jing-Ke et al.
Object Type: Article
System: The UNT Digital Library
Loss of Migratory Traditions Makes the Endangered Patagonian Huemul Deer a Year-Round Refugee in Its Summer Habitat (open access)

Loss of Migratory Traditions Makes the Endangered Patagonian Huemul Deer a Year-Round Refugee in Its Summer Habitat

This article analyzes the historical spatiotemporal behavior of the huemul (Hippocamelus bisulcus), an endangered deer endemic to Patagonia. Losing migratory traditions is a major threat, and may explain their presently prevalent skeletal diseases, reduced longevity, and lacking recolonizations for most remaining huemul subpopulations.
Date: May 31, 2022
Creator: Flueck, Werner T.; Smith-Flueck, Jo Anne M.; Escobar, Miguel E.; Zuliani, Melina; Fuchs, Beat; Geist, Valerius et al.
Object Type: Article
System: The UNT Digital Library
An Efficient Synthesis of Deoxyrhapontigenin-3-O-β-d-glucuronide, a Brain-Targeted Derivative of Dietary Resveratrol, and Its Precursor 4′-O-Me-Resveratrol (open access)

An Efficient Synthesis of Deoxyrhapontigenin-3-O-β-d-glucuronide, a Brain-Targeted Derivative of Dietary Resveratrol, and Its Precursor 4′-O-Me-Resveratrol

Article discusses the identification of the brain-available phenol glucuronide metabolite deoxyrhapontigenin-3-O-β-d-glucuronide (5) in perfused rat brains following subacute treatment with the stilbene resveratrol.
Date: May 7, 2019
Creator: de Fátima, Ângelo; Docampo-Palacios, Maite; Alvarez-Hernandez, Anislay; Pasinetti, Giulio M. & Dixon, R. A.
Object Type: Article
System: The UNT Digital Library
Thermal Stress Has Minimal Effects on Bacterial Communities of Thermotolerant Symbiodinium Cultures (open access)

Thermal Stress Has Minimal Effects on Bacterial Communities of Thermotolerant Symbiodinium Cultures

Article comparing the microbial communities of three isolates from different species of the genus Symbiodinium (formerly known as Symbiodinium clade A) with different ecophysiology, levels of interaction with the animal host, and thermal adaptations. Results suggest that bacteria associated or co-cultured with thermotolerant Symbiodinium might play an important role in thermotolerance.
Date: May 19, 2022
Creator: Díaz-Almeyda, Erika M.; Ryba, Tyrone; Ohdera, Aki H.; Shafer, Natali; Link, Caroline; Prado-Zapata, Marcela et al.
Object Type: Article
System: The UNT Digital Library
Brassinosteroid Mediated Cell Wall Remodeling in Grasses Under Abiotic Stress (open access)

Brassinosteroid Mediated Cell Wall Remodeling in Grasses Under Abiotic Stress

This article focuses on recent advances in brassinosteroid-regulated cell wall biosynthesis and remodeling in response to stresses, comparing the authors' understanding of the mechanisms in grass species with those in the more studied dicots.
Date: May 17, 2017
Creator: Rao, Xiaolan & Dixon, R. A.
Object Type: Article
System: The UNT Digital Library
Physiological Regulation of Growth, Hematology and Blood Gases in Chicken Embryos in Response to Low and High Incubation Humidity (open access)

Physiological Regulation of Growth, Hematology and Blood Gases in Chicken Embryos in Response to Low and High Incubation Humidity

Article examining effects of Low relative humidity (25–35%), and High relative humidity (85–93%) on hatchability, embryonic growth, hematology and blood gases and pH in chicken embryos.
Date: May 24, 2022
Creator: Branum, Sylvia R.; Tazawa, Hiroshi & Burggren, Warren W.
Object Type: Article
System: The UNT Digital Library
Frontiers in Aquatic Physiology – grand challenge (open access)

Frontiers in Aquatic Physiology – grand challenge

Opinion article covering grand challenges to aquatic physiology based on the five "grand challenges in organismal biology" proposed by Schwenk et al. (2007). This article also provides a list of specific examples of emerging areas of research interest in aquatic physiology.
Date: May 18, 2010
Creator: Evans, David H.; Axelsson, Michael; Beltz, Barbara; Burggren, Warren W.; Castellini, Michael; Clements, Kendall D. et al.
Object Type: Article
System: The UNT Digital Library
Genetically engineered probiotic for the treatment of phenylketonuria (PKU); assessment of a novel treatment in vitro and in the PAHᵉⁿᵘ² mouse model of PKU (open access)

Genetically engineered probiotic for the treatment of phenylketonuria (PKU); assessment of a novel treatment in vitro and in the PAHᵉⁿᵘ² mouse model of PKU

This article describes the testing of a phenylalanine lyase gene from Anabaena variabilis (AvPAL) codon-optimized and cloned into a shuttle vector for expression in Lactobacillus reuteri 100-23C (pHENOMMenal).
Date: May 17, 2017
Creator: Durrer, Katherine E.; Allen, Michael S. & Hunt von Herbing, Ione
Object Type: Article
System: The UNT Digital Library
Altered expression of ionotropic L-Glutamate receptors in aged sensory neurons of Aplysia californica (open access)

Altered expression of ionotropic L-Glutamate receptors in aged sensory neurons of Aplysia californica

Article describes study in which mRNA expression of iGluR was quantified in two sensory neuron clusters of two cohorts of Aplysia californica (Aplysia) at both sexual maturity (~8 months) and advanced age (~12 months) in order to examine if changes in ionotropic L-Glu receptor (iGluR) transcription underlie reduced physiology8
Date: May 23, 2019
Creator: Greer, Justin B.; Mager, Edward M. & Fieber, Lynne A.
Object Type: Article
System: The UNT Digital Library
G-RISE at the University of North Texas (open access)

G-RISE at the University of North Texas

Data management plan for the grant "G-RISE at the University of North Texas." The University of North Texas (UNT) serves over 32,000 undergraduate and 7,000 graduate students of which 50% of the undergraduate population and 20% of the graduate population are underrepresented minority (URM). UNT is ranked by the Carnegie Classification as a Tier 1 institute, is a Hispanic Serving Institute, and is dedicated to providing quality mentoring to a diverse group of Ph.D. students. The UNT G-­RISE mission is to provide a biomedical Ph.D. training program that is inclusive, culturally responsive, increases diversity, enhances scientific skill sets, develops trainee career and professional skill sets, provides opportunities to participants, and increases faculty development as a mentor.
Date: 2021-05-01/2022-04-30
Creator: Padilla, Pamela A.; Burggren, Warren W.; Cisneros, Gerardo Andrés & Hughes, Lee E.
Object Type: Text
System: The UNT Digital Library
Systemic signaling during abiotic stress combination in plants (open access)

Systemic signaling during abiotic stress combination in plants

Article reveals that plants can integrate different local and systemic signals generated during conditions of stress combination. Furthermore, results show that the specific part at which plants sense the two co-occurring stresses makes a significant difference in how fast and efficient they acclimate.
Date: May 29, 2020
Creator: Sengupta, Soham; Azad, Rajeev K.; Zandalinas, Sara I.; Fichman, Yosef; Devireddy, Amith R. & Mittler, Ron
Object Type: Article
System: The UNT Digital Library
Combining loss of function of FOLYLPOLYGLUTAMATE SYNTHETASE1 and CAFFEOYL-COA 3-O-METHYLTRANSFERASE1 for lignin reduction and improved saccharification efficiency in Arabidopsis thaliana (open access)

Combining loss of function of FOLYLPOLYGLUTAMATE SYNTHETASE1 and CAFFEOYL-COA 3-O-METHYLTRANSFERASE1 for lignin reduction and improved saccharification efficiency in Arabidopsis thaliana

This article tests if lignin content can be further reduced by combining genetic mutations in C1 metabolism and the lignin biosynthetic pathway by generating and functionally characterizing fpgs1ccoaomt1 double mutants. The observations demonstrate that additional reduction in lignin content and improved sugar release can be achieved by simultaneous downregulation of a gene in the C1 (FPGS1) and lignin biosynthetic (CCOAOMT) pathways.
Date: December 31, 2018
Creator: Xie, Hongli; Engle, Nancy L.; Venketachalam, Sivasankari; Yoo, Chang Geun; Barros, Jaime; Lecoultre, Mitch et al.
Object Type: Article
System: The UNT Digital Library
Agronomic Performance and Lignin Content of HCT Down-Regulated Alfalfa (Medicago sativa L.) (open access)

Agronomic Performance and Lignin Content of HCT Down-Regulated Alfalfa (Medicago sativa L.)

This article evaluates HCT down-regulated alfalfa plants for their forage composition and agronomic performance in the greenhouse and under field conditions.
Date: May 5, 2018
Creator: Bhattarai, Kishor; Rajasekar, Shanmugam; Dixon, R. A. & Monteros, Maria J.
Object Type: Article
System: The UNT Digital Library
Combining loss of function of FOLYLPOLYGLUTAMATE SYNTHETASE1 and CAFFEOYL-COA 3-O-METHYLTRANSFERASE1 for lignin reduction and improved saccharification efficiency in Arabidopsis thaliana (open access)

Combining loss of function of FOLYLPOLYGLUTAMATE SYNTHETASE1 and CAFFEOYL-COA 3-O-METHYLTRANSFERASE1 for lignin reduction and improved saccharification efficiency in Arabidopsis thaliana

Article describes study in which fpgs1ccoaomt1 double mutants were generated and functionally characterized in order to test if lignin content can be further reduced by combining genetic mutations in C1 metabolism and the lignin biosynthetic pathway.
Date: May 3, 2019
Creator: Xie, Hongli; Engle, Nancy L.; Venketachalam, Sivasankari; Yoo, Chang Geun; Barros, Jaime; Lecoultre, Mitch et al.
Object Type: Article
System: The UNT Digital Library
Generation of transgenic zebrafish with 2 populations of RFP- and GFP-labeled thrombocytes: analysis of their lipids (open access)

Generation of transgenic zebrafish with 2 populations of RFP- and GFP-labeled thrombocytes: analysis of their lipids

Article analyzing the lipids in transgenic zebrafish. Separating RFP+ and GFP+ thrombocytes from the GloFli fish developed here led to the analysis of their lipid composition.DiI-labeled liposomes with similar PE and PC concentrations found in RFP+ thrombocytes explained DiI labeling of thrombocytes.
Date: July 23, 2018
Creator: Fallatah, Weam; De Silva, Imesha W.; Verbeck, Guido F. & Jagadeeswaran, Pudur
Object Type: Article
System: The UNT Digital Library
Transcriptional Programs and Regulators Underlying Age-Dependent and Dark-Induced Senescence in Medicago truncatula (open access)

Transcriptional Programs and Regulators Underlying Age-Dependent and Dark-Induced Senescence in Medicago truncatula

Article presents a study that reveals the dynamics of transcriptomic responses to age- and dark-induced senescence in M. truncatula and identifies senescence-associated TFs that are attractive targets for future work to control senescence in forage legumes.
Date: May 6, 2022
Creator: Mahmood, Kashif; Torres-Jerez, Ivone; Krom, Nick; Liu, Wei & Udvardi, Michael K.
Object Type: Article
System: The UNT Digital Library
Formation of cotton bast fiber as a means to modulate carbon capture and increase bio-product utilization (open access)

Formation of cotton bast fiber as a means to modulate carbon capture and increase bio-product utilization

Data management plan for the grant "Formation of cotton bast fiber as a means to modulate carbon capture and increase bio-product utilization."
Date: 2023-05-01/2026-04-30
Creator: Ayre, Brian G.
Object Type: Text
System: The UNT Digital Library
A conserved oxalyl-coenzyme A decarboxylase in oxalate catabolism (open access)

A conserved oxalyl-coenzyme A decarboxylase in oxalate catabolism

Article presents research on oxalate catabolism in plants.
Date: May 5, 2022
Creator: Cheng, Ninghui; Paris, Vincent; Rao, Xiaolan; Wang, Xiaoqiang & Nakata, Paul A.
Object Type: Article
System: The UNT Digital Library