Targeting the pattern-triggered immunity pathway to enhance resistance to Fusarium graminearum (open access)

Targeting the pattern-triggered immunity pathway to enhance resistance to Fusarium graminearum

Article describes study which shows that resistance against fusarium graminearum, the primary casual agent of fusarium head blight (FHB), can be enhanced by flg22, a bacterial microbe-associated molecular pattern (MAMP).
Date: February 6, 2019
Creator: Sarowar, Sujon; Alam, Syeda T.; Makandar, Ragiba; Lee, Hyeonju; Trick, Harold N.; Dong, Yanhong et al.
System: The UNT Digital Library
RNA helicase DP103 and TAK1: a new connection in cancer (open access)

RNA helicase DP103 and TAK1: a new connection in cancer

Article on new markers of tumor metastasis. The authors found that expression of DP103 was significantly upregulated in the metastatic basal subtype of breast cancers in 3 independent cohorts. This elevated DP103 expression correlated with metastatic breast cancer gene signatures and was strongly associated with patient survival. This study provides the first evidence that the RNA helicase DEAD-box protein DP103 is an NF-kB target that could form part of a positive feedback loop contributing to DP103- mediated regulation of TAK1 kinase activity on the major NF-kB kinase IKK2, thus implicating DP103 in the maintenance of this oncogenic signaling arm in human cancer.
Date: May 6, 2015
Creator: Shin, Eun Myoung; Osato, Motomi; Kumar, Alan Prem & Tergaonkar, Vinay
System: The UNT Digital Library
Inhibition of Very Long Chain Fatty Acids Synthesis Mediates PI3P Homeostasis at Endosomal Compartments (open access)

Inhibition of Very Long Chain Fatty Acids Synthesis Mediates PI3P Homeostasis at Endosomal Compartments

This article uses metazachlor, an inhibitor of VLCFA synthesis, to find that VLCFAs are involved in the TGN/MVB distribution of PI3P. This effect is independent from either synthesis of PI3P by PI3-kinase or degradation of PI(3,5)P2 into PI3P by the SUPPRESSOR OF ACTIN1 (SAC1) phosphatase. Results suggest that PI3P might be transferable from TGN to MVBs and that VLCFAs act in this process.
Date: August 6, 2021
Creator: Ito, Yoko; Esnay, Nicolas; Fougère, Louise; Platre, Matthieu Pierre; Cordelières, Fabrice; Jaillais, Yvon et al.
System: The UNT Digital Library
Identification and characterization of a core set of ROS wave‐associated transcripts involved in the systemic acquired acclimation response of Arabidopsis to excess light (open access)

Identification and characterization of a core set of ROS wave‐associated transcripts involved in the systemic acquired acclimation response of Arabidopsis to excess light

Article reveal that the systemic transcriptomic response of plants to excess light stress is extensive in the context of systemic acquired acclimation and involves an early (2 min) and transient stage of transcript expression that includes thousands of genes.
Date: December 6, 2018
Creator: Zandalinas, Sara I.; Sengupta, Soham; Burks, David; Azad, Rajeev K. & Mittler, Ron
System: The UNT Digital Library
The Cluster Transfer Function of AtNEET Supports the Ferredoxin–Thioredoxin Network of Plant Cells (open access)

The Cluster Transfer Function of AtNEET Supports the Ferredoxin–Thioredoxin Network of Plant Cells

This article develops an inducible expression system to study AtNEET function in mature plants using a time-course proteomics approach. The authors report that the suppression of AtNEET cluster transfer function results in drastic changes in the expression of different members of the ferredoxin (Fd), Fd-thioredoxin (TRX) reductase (FTR), and TRX network of Arabidopsis, as well as in cytosolic cluster assembly proteins.
Date: August 6, 2022
Creator: Zandalinas, Sara I.; Song, Luhua; Nechushtai, Rachel; Mendoza-Cózatl, David & Mittler, Ron
System: The UNT Digital Library
Histological features of non-alcoholic fatty liver disease revealed in response to mixed vehicle emission exposure and consumption of a high-fat diet in wildtype C57Bl/6 male mice (open access)

Histological features of non-alcoholic fatty liver disease revealed in response to mixed vehicle emission exposure and consumption of a high-fat diet in wildtype C57Bl/6 male mice

Article describes how non-alcoholic fatty liver disease (NAFLD) is currently plaguing the population at pandemic proportions and is expected to become more prevalent over the next decade. The authors investigated the hypothesis that exposure to a mixture of gasoline and diesel engine emissions (MVE), coupled with the concurrent consumption of a HF diet, promotes the development of a NAFLD phenotype within the liver.
Date: June 6, 2023
Creator: Schneider, Leah J.; Santiago, Isabella; Johnson, Bailee; Stanley, Analana Hays; Penaredondo, Bea & Lund, Amie K.
System: The UNT Digital Library
Developmental programming of DNA methylation and gene expression patterns is associated with extreme cardiovascular tolerance to anoxia in the common snapping turtle (open access)

Developmental programming of DNA methylation and gene expression patterns is associated with extreme cardiovascular tolerance to anoxia in the common snapping turtle

This article explores DNA methylation's role in the regulation of gene expression in reptiles. Results show that embryonic hypoxia programs DNA methylation and gene expression patterns and that these changes are associated with enhanced cardiac anoxia tolerance in snapping turtles later in life.
Date: September 6, 2021
Creator: Ruhr, Ilan; Bierstedt, Jacob; Rhen, Turk; Das, Debojyoti; Singh, Sunil Kumar; Miller, Solielle et al.
System: The UNT Digital Library
A metabolomic platform to identify and quantify polyphenols in coffee and related species using liquid chromatography mass spectrometry (open access)

A metabolomic platform to identify and quantify polyphenols in coffee and related species using liquid chromatography mass spectrometry

Article describes how products of plant secondary metabolism, such as phenolic compounds, flavonoids, alkaloids, and hormones, play an important role in plant growth, development, stress resistance. The authors state that the overall goal of this study was to develop a high-throughput workflow to identify and quantify plant polyphenols.
Date: January 6, 2023
Creator: Castro-Moretti, Fernanda R.; Cocuron, Jean-Christophe; Castillo-Gonzalez, Humberto; Escudero-Leyva, Efrain; Chaverri, Priscila; Guerreiro-Filho, Oliveiro et al.
System: The UNT Digital Library
Developmental plasticity of cardiac anoxia-tolerance in juvenile common snapping turtles ( Chelydra serpentina) (open access)

Developmental plasticity of cardiac anoxia-tolerance in juvenile common snapping turtles ( Chelydra serpentina)

Article describes study which tested the hypothesis that developmental hypoxia alters cardiomyocyte physiology in a manner that protects the heart from hypoxic stress.
Date: June 6, 2019
Creator: Ruhr, Ilan M.; McCourty, Heather; Bajjig, Afaf; Crossley, Dane A., II; Shiels, Holly A. & Galli, Gina L. J.
System: The UNT Digital Library
Fatty acid amide hydrolase and 9-lipoxygenase  modulate cotton seedling growth by ethanolamide  oxylipin levels (open access)

Fatty acid amide hydrolase and 9-lipoxygenase modulate cotton seedling growth by ethanolamide oxylipin levels

Article asserts that polyunsaturated N-acylethanolamines (NAEs) can be hydrolyzed by fatty acid amide hydrolase (FAAH) or oxidized by lipoxygenase (LOX). Altogether, the authors conclude that the growth of cotton seedlings involves fine-tuning of 9-NAE-HOD levels via FAAH-mediated hydrolysis and LOX-mediated production, expanding the mechanistic understanding of plant growth modulation by NAE oxylipins to a perennial crop species.
Date: December 6, 2022
Creator: Gaguancela-Arias, Omar; Aziz, Mina & Chapman, Kent Dean
System: The UNT Digital Library
State of the world's raptors: Distributions, threats, and conservation recommendations (open access)

State of the world's raptors: Distributions, threats, and conservation recommendations

Article exploring the International Union for the Conservation of Nature's Red List to examine the conservation status, distributions, threats, and conservation recommendations for all 557 raptor species.
Date: September 6, 2018
Creator: McClure, Christopher J.W.; Westrip, James R.S.; Johnson, Jeff A.; Schulwitz, Sarah; Virani, Munir Z.; Davies, Robert et al.
System: The UNT Digital Library
Transcriptional Programs and Regulators Underlying Age-Dependent and Dark-Induced Senescence in Medicago truncatula (open access)

Transcriptional Programs and Regulators Underlying Age-Dependent and Dark-Induced Senescence in Medicago truncatula

Article presents a study that reveals the dynamics of transcriptomic responses to age- and dark-induced senescence in M. truncatula and identifies senescence-associated TFs that are attractive targets for future work to control senescence in forage legumes.
Date: May 6, 2022
Creator: Mahmood, Kashif; Torres-Jerez, Ivone; Krom, Nick; Liu, Wei & Udvardi, Michael K.
System: The UNT Digital Library