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A multiscale approach reveals elaborate circulatory system and intermittent heartbeat in velvet worms (Onychophora) (open access)

A multiscale approach reveals elaborate circulatory system and intermittent heartbeat in velvet worms (Onychophora)

Article describes how an antagonistic hemolymph-muscular system is essential for soft-bodied invertebrates. The authors analyzed the entire circulatory system of the peripatopsid Euperipatoides rowelli and claimed they discovered a surprisingly elaborate organization.
Date: April 28, 2023
Creator: Jahn, Henry; Hammel, Jörg U.; Göpel, Torben; Wirkner, Christian S. & Mayer, Georg
System: The UNT Digital Library
Complexity Synchronization of Organ Networks (open access)

Complexity Synchronization of Organ Networks

Article describes how the transdisciplinary nature of science as a whole became evident as the necessity for the complex nature of phenomena to explain social and life science, along with the physical sciences, blossomed into complexity theory and most recently into complexitysynchronization. The authors use the scaling of empirical datasets from the brain, cardiovascular and respiratory networks to support the hypothesis that complexity synchronization occurs between scaling indices or equivalently with the matching of the time dependencies of the networks' multifractal dimensions.
Date: September 28, 2023
Creator: West, Bruce J.; Grigolini, Paolo; Kerick, Scott E.; Franaszczuk, Piotr J. & Mahmoodi, Korosh
System: The UNT Digital Library
Preferential Solvation Study of Rosuvastatin in the {PEG400 (1) + Water (2)} Cosolvent Mixture and GastroPlus Software-Based In Vivo Predictions (open access)

Preferential Solvation Study of Rosuvastatin in the {PEG400 (1) + Water (2)} Cosolvent Mixture and GastroPlus Software-Based In Vivo Predictions

Article claims that rosuvastatin (RST) is a poorly water-soluble drug responsible for limited in vivo dissolution and subsequently low oral systemic absorption (poor bioavailability). The results of inverse Kirkwood–Buff integrals showed the PS of RST by PEG400 as observed in all studied ratios of the binary mixture.
Date: March 28, 2023
Creator: Hussain, Afzal; Afzal, Obaid; Yasmin, Sabina; Haider, Nazima; Alfawaz Altamimi, Abdulmalik Saleh; Martínez, Fleming et al.
System: The UNT Digital Library
Prebiotic/probiotic supplementation resulted in reduced visceral fat and mRNA expression associated with adipose tissue inflammation, systemic inflammation, and chronic disease risk (open access)

Prebiotic/probiotic supplementation resulted in reduced visceral fat and mRNA expression associated with adipose tissue inflammation, systemic inflammation, and chronic disease risk

Article describes how prebiotic/probiotic supplementation represents a viable option for addressing elevated systemic inflammation and chronic disease risk in overweight individuals. The key findings support that 90-day prebiotic/probiotic supplementation may be associated with reduced adipose tissue inflammation, reduced systemic inflammation, and reduced chronic disease risk.
Date: November 28, 2022
Creator: McFarlin, Brian K.; Tanner, Elizabeth A.; Hill, David W. & Vingren, Jakob L.
System: The UNT Digital Library
Multi-omic characterization of bifunctional peroxidase 4-coumarate 3-hydroxylase knockdown in Brachypodium distachyon provides insights into lignin modification associated pleiotropic effects (open access)

Multi-omic characterization of bifunctional peroxidase 4-coumarate 3-hydroxylase knockdown in Brachypodium distachyon provides insights into lignin modification associated pleiotropic effects

Article discusses how a bifunctional peroxidase enzyme, 4-coumarate 3-hydroxylase (C3H/APX), provides a parallel route to the shikimate shunt pathway for the conversion of 4-coumarate to caffeate in the early steps of lignin biosynthesis. Here, a multi-omic approach was used to characterize molecular changes resulting from C3H/APX-KD associated lignin modification and negative growth phenotype in Brachypodium distachyon.
Date: September 28, 2022
Creator: Shrestha, Him K.; Fichman, Yosef; Engle, Nancy L.; Tschaplinski, Timothy J.; Mittler, Ron; Dixon, R. A. et al.
System: The UNT Digital Library
Efficient separation of xylene isomers by a guest-responsive metal–organic framework with rotational anionic sites (open access)

Efficient separation of xylene isomers by a guest-responsive metal–organic framework with rotational anionic sites

Article demonstrating the adaptively molecular discrimination of xylene isomers by employing a NbOF52−-pillared metal–organic framework (NbOFFIVE-bpy-Ni, also referred to as ZU-61) with rotational anionic sites.
Date: October 28, 2020
Creator: Cui, Xili; Niu, Zheng; Shan, Chuan; Yang, Lifeng; Hu, Jianbo; Wang, Qingju et al.
System: The UNT Digital Library
Crowdsourcing biocuration: the Community Assessment of Community 1 Annotation with Ontologies (CACAO) (open access)

Crowdsourcing biocuration: the Community Assessment of Community 1 Annotation with Ontologies (CACAO)

Article describing an approach to expand biocuration through crowdsourcing with undergraduates in the community-oriented wiki framework for GO annotation called the Gene Ontology Normal Usage Tracking System (GONUTS). This multiplies the number of high-quality annotations in international databases, enriches the coverage of the literature on normal gene function, and pushes the field in new directions.
Date: October 28, 2021
Creator: Ramsey, Jolene; McIntosh, Brenley; Renfro, Daniel; Aleksander, Susan A.; LaBonte, Sandra; Ross, Curtis et al.
System: The UNT Digital Library
The Long-Term Effects of Developmental Hypoxia on Cardiac Mitochondrial Function in Snapping Turtles (open access)

The Long-Term Effects of Developmental Hypoxia on Cardiac Mitochondrial Function in Snapping Turtles

This article investigates the long-term effects of developmental hypoxia on mitochondrial function in a species that regularly encounters hypoxia during development. Findings speculate that adjustments might improve mitochondrial hypoxia tolerance, which would be beneficial for turtles during breath-hold diving and overwintering in anoxic environments.
Date: June 28, 2021
Creator: Galli, Gina L. J.; Ruhr, Ilan M.; Crossley, Janna & Crossley, Dane A., II
System: The UNT Digital Library
Migratory movements of Atlantic puffins Fratercula arctica naumanni from high Arctic Greenland (open access)

Migratory movements of Atlantic puffins Fratercula arctica naumanni from high Arctic Greenland

This article is the first to present data on the migratory movements of the “large-billed” subspecies, F. a. naumanni, that breeds in the high Arctic and which has significantly larger body size than those farther south.
Date: May 28, 2021
Creator: Burnham, Kurt K.; Burnham, Jennifer L.; Johnson, Jeff A. & Huffman, Abby
System: The UNT Digital Library
Sarcoplasmic reticulum Ca²⁺-ATPase (SERCA) activity during the transition to endothermy in an altricial bird (open access)

Sarcoplasmic reticulum Ca²⁺-ATPase (SERCA) activity during the transition to endothermy in an altricial bird

Article describes SERCA activity in the pectoralis muscle and heart ventricle of red-winged blackbird (Agelaius phoeniceus) nestlings, fledglings and adults. Additionally, using a diet manipulation, the authors tested the hypothesis that muscle SERCA activity is affected by dietary fatty acid composition, as has been shown in some previous studies.
Date: June 28, 2019
Creator: Price, Edwin R.; Sirsat, Tushar S.; Sirsat, Sarah K. G. & Dzialowski, Edward M. (Edward Michael)
System: The UNT Digital Library
An “ideal lignin” facilitates full biomass utilization (open access)

An “ideal lignin” facilitates full biomass utilization

This article describes the ideal nature of the Catechyl lignin (C-lignin) via a revised compositional characterization of the vanilla seed coat fiber, new features of the C-lignin's reactivity and stability, and successful attempts at converting it to monomers in near-quantitative yields.
Date: September 28, 2018
Creator: Li, Yanding; Shuai, Li; Kim, Hoon; Hussain Motagamwala, Ali; Mobley, Justin K.; Yue, Fengxia et al.
System: The UNT Digital Library