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A Small Compound Targeting Prohibitin with Potential Interest for Cognitive Deficit Rescue in Aging mice and Tau Pathology Treatment
Article describes study analyzing the effects of a new purine derivative drug, PDD005, in attenuating mechanisms involved in the pathogenesis of neurodegenerative diseases, using both in vivo and in vitro models.
Date:
January 24, 2020
Creator:
Guyot, Anne-Cécile; Leuxe, Charlotte; Disdier, Clémence; Oumata, Nassima; Costa, Narciso; Le Roux, Gwenaëlle et al.
System:
The UNT Digital Library
Spin Hall effect in prototype Rashba ferroelectrics GeTe and SnTe
Article describes study investigating spin Hall effect (SHE) in two prototypical Ferroelectric Rashba semiconductors (FERSCs), GeTe and SnTe, and show that it can be large either in ferroelectric or paraelectric structure.
Date:
January 24, 2020
Creator:
Wang, Haihang; Gopal, Priya; Picozzi, Silvia; Curtarolo, Stefano; Buongiorno Nardelli, Marco & Sławińska, Jagoda
System:
The UNT Digital Library
Metabolic reprogramming underlies cavefish muscular endurance despite loss of muscle mass and contractility
Article discusses the Mexican cavefish Astyanax mexicanus, has lost moderate-to-vigorous activity following cave colonization, reaching basal swim speeds ~3.7-fold slower than their river-dwelling counterpart. Collectively, the authors reveal broad skeletal muscle changes following cave colonization, displaying an adaptive skeletal muscle phenotype reminiscent to mammalian disuse and high-fat models while simultaneously maintaining a unique capacity for sustained muscle contraction via enhanced glycogen metabolism.
Date:
January 24, 2023
Creator:
Olsen, Luke; Levy, Michaella; Medley, J. Kyle; Hassan, Huzaifa; Miller, Brandon; Alexander, Richard et al.
System:
The UNT Digital Library