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Inhibition of Very Long Chain Fatty Acids Synthesis Mediates PI3P Homeostasis at Endosomal Compartments
This article uses metazachlor, an inhibitor of VLCFA synthesis, to find that VLCFAs are involved in the TGN/MVB distribution of PI3P. This effect is independent from either synthesis of PI3P by PI3-kinase or degradation of PI(3,5)P2 into PI3P by the SUPPRESSOR OF ACTIN1 (SAC1) phosphatase. Results suggest that PI3P might be transferable from TGN to MVBs and that VLCFAs act in this process.
Date:
August 6, 2021
Creator:
Ito, Yoko; Esnay, Nicolas; Fougère, Louise; Platre, Matthieu Pierre; Cordelières, Fabrice; Jaillais, Yvon et al.
System:
The UNT Digital Library
The Cluster Transfer Function of AtNEET Supports the Ferredoxin–Thioredoxin Network of Plant Cells
This article develops an inducible expression system to study AtNEET function in mature plants using a time-course proteomics approach. The authors report that the suppression of AtNEET cluster transfer function results in drastic changes in the expression of different members of the ferredoxin (Fd), Fd-thioredoxin (TRX) reductase (FTR), and TRX network of Arabidopsis, as well as in cytosolic cluster assembly proteins.
Date:
August 6, 2022
Creator:
Zandalinas, Sara I.; Song, Luhua; Nechushtai, Rachel; Mendoza-Cózatl, David & Mittler, Ron
System:
The UNT Digital Library