Resource Type

Association between CYP2D6 Genotypes and the Risk of Antidepressant Discontinuation, Dosage Modification and the Occurrence of Maternal Depression during Pregnancy (open access)

Association between CYP2D6 Genotypes and the Risk of Antidepressant Discontinuation, Dosage Modification and the Occurrence of Maternal Depression during Pregnancy

This article investigates the association between CYP2D6 genotype and the risk of antidepressant discontinuation, dosage modification, and the occurrence of maternal CYP2D6, Antidepressants, Depression during pregnancy.
Date: July 17, 2017
Creator: Bérard, Anick; Gaedigk, Andrea; Sheehy, Odile; Chambers, Christina; Roth, Mark; Bozzo, Pina et al.
System: The UNT Digital Library
A modified aeroponic system for growing small-seeded legumes and other plants to study root systems (open access)

A modified aeroponic system for growing small-seeded legumes and other plants to study root systems

Authors of the article state that various growth systems are available for studying plant root growth and plant–microbe interactions including hydroponics and aeroponics. The aim of their study is to present step-by-step instructions for fabricating an aeroponic system, also called a “caisson,” that has been in use in several legume research labs studying the development of symbiotic nitrogen fixing nodules, but for which detailed directions are not currently available.
Date: March 3, 2023
Creator: Cai, Jingya; Veerappan, Vijaykumar; Arildsen, Kate; Sullivan, Catrina; Piechowicz, Megan; Frugoli, Julia et al.
System: The UNT Digital Library
Correction: A modified aeroponic system for growing small-seeded legumes and other plants to study root systems (open access)

Correction: A modified aeroponic system for growing small-seeded legumes and other plants to study root systems

This is a correction to an article. The affiliation of the first author was published incorrectly.
Date: March 25, 2023
Creator: Cai, Jingya; Veerappan, Vijaykumar; Arildsen, Kate; Sullivan, Catrina; Piehowicz, Megan; Frugoli, Julia et al.
System: The UNT Digital Library
Case report: Early-onset osteoporosis in a patient carrying a novel heterozygous variant of the WNT1 gene (open access)

Case report: Early-onset osteoporosis in a patient carrying a novel heterozygous variant of the WNT1 gene

Article presents a case study of a 35 year-old Caucasian woman who experienced multiple vertebral fractures two months after her second pregnancy. The results suggest a potential role of heterozygous WNT1 variants in the pathogenesis of early-onset osteoporosis. The authors suggest that teriparatide is one of the most appropriate available therapies for such cases.
Date: August 8, 2022
Creator: Campopiano, Maria Cristina; Fogli, Antonella; Michelucci, Angela; Mazoni, Laura; Longo, Antonella; Borsari, Simona et al.
System: The UNT Digital Library
Lipophilic signals lead to organ-specific gene expression changes in Arabidopsis seedlings (open access)

Lipophilic signals lead to organ-specific gene expression changes in Arabidopsis seedlings

Article presents a study where whole transcriptome sequencing (RNA-seq) and differential expression analysis were used to identify early (1–3 hr) transcriptional changes induced by the exogenous treatment of NAE 18:2 and NAE 18:3 in cotyledons, roots, and seedlings.
Date: July 15, 2020
Creator: Cannon, Ashley E.; Yan, Chengshi; Burks, David J.; Rao, Xiaolan; Azad, Rajeev K. & Chapman, Kent Dean
System: The UNT Digital Library
Transcriptome Analysis Uncovers the Gene Expression Profile of Hemileia vastatrix (Race XXXIII) during the Interactions with Resistant and Susceptible Coffee (open access)

Transcriptome Analysis Uncovers the Gene Expression Profile of Hemileia vastatrix (Race XXXIII) during the Interactions with Resistant and Susceptible Coffee

This article presents research to sequence the transcriptome of H. vastatrix race XXXIII to obtain a database for use as a reference in studies of the interaction between the fungus and coffee. In addition, the authors aim to identify differentially expressed genes that have the potential to act as effector proteins during the interaction.
Date: December 27, 2021
Creator: Castro, Isabel Samila Lima; Freitas-Lopes, Rejane do Livramento; de Siqueira Ferreira, Sávio; Maciel, Talles Eduardo Ferreira; Florez, Juan Carlos; Zambolim, Eunize Maciel et al.
System: The UNT Digital Library
A metabolomic platform to identify and quantify polyphenols in coffee and related species using liquid chromatography mass spectrometry (open access)

A metabolomic platform to identify and quantify polyphenols in coffee and related species using liquid chromatography mass spectrometry

Article describes how products of plant secondary metabolism, such as phenolic compounds, flavonoids, alkaloids, and hormones, play an important role in plant growth, development, stress resistance. The authors state that the overall goal of this study was to develop a high-throughput workflow to identify and quantify plant polyphenols.
Date: January 6, 2023
Creator: Castro-Moretti, Fernanda R.; Cocuron, Jean-Christophe; Castillo-Gonzalez, Humberto; Escudero-Leyva, Efrain; Chaverri, Priscila; Guerreiro-Filho, Oliveiro et al.
System: The UNT Digital Library
Targeted Metabolic Profiles of the Leaves and Xylem Sap of Two Sugarcane Genotypes Infected with the Vascular Bacterial Pathogen Leifsonia xyli subsp. xyli (open access)

Targeted Metabolic Profiles of the Leaves and Xylem Sap of Two Sugarcane Genotypes Infected with the Vascular Bacterial Pathogen Leifsonia xyli subsp. xyli

This article identifies discriminant metabolites between a resistant (R) and a susceptible (S) sugarcane variety at the early stages of pathogen colonization (30 and 120 days after inoculation—DAI) by untargeted and targeted metabolomics of leaves and xylem sap using gas chromatography-mass spectrometry (GC-MS) and liquid chromatography-tandem mass spectrometry (LC-MS/MS). The data represent a valuable resource of potential biomarkers for metabolite-assisted selection of resistant varieties to RS.
Date: April 12, 2021
Creator: Castro-Moretti, Fernanda R.; Cocuron, Jean-Christophe; Cia, Maria C.; Cataldi, Thais R.; Labate, Carlos A.; Alonso, Ana Paula et al.
System: The UNT Digital Library
Metabolomics as an Emerging Tool for the Study of Plant–Pathogen Interactions (open access)

Metabolomics as an Emerging Tool for the Study of Plant–Pathogen Interactions

Paper discusses metabolomics studies that link changes in primary or specialized metabolism to the defense responses of plants against bacterial, fungal, nematode, and viral pathogens.
Date: January 29, 2020
Creator: Castro-Moretti, Fernanda R.; Gentzel, Irene N.; Mackey, David & Alonso, Ana Paula
System: The UNT Digital Library
Compartmentation of Triacylglycerol Accumulation in Plants (open access)

Compartmentation of Triacylglycerol Accumulation in Plants

Article studying an underappreciated complexity in pathways for synthesis and accumulation of Triacylglycerols from plants, familiar to most people as vegetable oils.
Date: January 20, 2012
Creator: Chapman, Kent Dean & Ohlrogge, John B.
System: The UNT Digital Library
A rapid thioacidolysis method for biomass lignin composition and tricin analysis (open access)

A rapid thioacidolysis method for biomass lignin composition and tricin analysis

This article developed a modified, rapid higher throughput thioacidolysis method to analyze both lignin monomeric composition and tricin content in the lignin polymer. The results demonstrate that the modified method can be used for rapid, high-throughput, and reliable lignin composition and tricin content analyses for screening transgenic plants for cell wall modifications or in large-scale genome-wide association studies (GWAS).
Date: January 11, 2021
Creator: Chen, Fang; Zhuo, Chunliu; Xiao, Xirong; Pendergast, Thomas H. & Devos, Katrien M.
System: The UNT Digital Library
A conserved oxalyl-coenzyme A decarboxylase in oxalate catabolism (open access)

A conserved oxalyl-coenzyme A decarboxylase in oxalate catabolism

Article presents research on oxalate catabolism in plants.
Date: May 5, 2022
Creator: Cheng, Ninghui; Paris, Vincent; Rao, Xiaolan; Wang, Xiaoqiang & Nakata, Paul A.
System: The UNT Digital Library
Local and Systemic Metabolic Responses during Light-Induced Rapid Systemic Signaling (open access)

Local and Systemic Metabolic Responses during Light-Induced Rapid Systemic Signaling

This article reports that local application of light stress to one rosette leaf of bolting Arabidopsis (Arabidopsis thaliana) plants resulted in a metabolic response that encompassed local, systemic and transport tissues, demonstrating a high degree of physical and metabolic continuity between different tissues throughout the plant.
Date: December 2018
Creator: Choudhury, Feroza K.; Devireddy, Amith R.; Azad, Rajeev K.; Shulaev, Vladimir & Mittler, Ron
System: The UNT Digital Library
The EAR-motif of the Cys2/His2-type Zinc Finger Protein Zat7 Plays a Key Role in the Defense Response of Arabidopsis to Salinity Stress (open access)

The EAR-motif of the Cys2/His2-type Zinc Finger Protein Zat7 Plays a Key Role in the Defense Response of Arabidopsis to Salinity Stress

Article reporting that transgenic Arabidopsis plants constitutively expressing the Cys2/His2 zinc finger protein Zat7 have suppressed growth and are more tolerant to salinity stress. Findings demonstrate that the EAR-domain of Cys2/His2-type zinc finger proteins plays a key role in the defense response of Arabidopsis to abiotic stresses.
Date: March 23, 2007
Creator: Ciftci-Yilmaz, Sultan; Morsy, Mustafa R.; Song, Luhua; Coutu, Alicia; Krizek, Beth A.; Lewis, Michael W. et al.
System: The UNT Digital Library
Non-conventional pathways enable pennycress (Thlaspi arvense L.) embryos to achieve high efficiency of oil biosynthesis (open access)

Non-conventional pathways enable pennycress (Thlaspi arvense L.) embryos to achieve high efficiency of oil biosynthesis

Article exploring how to improve oil production in Pennycress (Thlaspi arvense L.).
Date: February 1, 2020
Creator: Cocuron, Jean-Christophe; Alonso, Ana Paula & Tsogtbaatar, Enkhtuul
System: The UNT Digital Library
Beyond the wall: High-throughput quantification of plant soluble and cell-wall bound phenolics by liquid chromatography tandem mass spectrometry (open access)

Beyond the wall: High-throughput quantification of plant soluble and cell-wall bound phenolics by liquid chromatography tandem mass spectrometry

Article describes a study in which a novel high-throughput ultra-high performance liquid chromatography tandem mass spectrometry (UHPLC–MS/MS) method was established to quantify the levels of 19 flavonoids and 15 other phenolic compounds, including acids, aldehydes, and alcohols.
Date: December 26, 2018
Creator: Cocuron, Jean-Christophe; Casas, Maria Isabel; Yang, Fan & Grotewold, Erich
System: The UNT Digital Library
Liquid Chromatography Tandem Mass Spectrometry Quantification of ¹³C-Labeling in Sugars (open access)

Liquid Chromatography Tandem Mass Spectrometry Quantification of ¹³C-Labeling in Sugars

This article describes a new methodology for monitoring sucrose labeling using liquid chromatography tandem mass spectrometry (LC-MS/MS). To date, the most commonly used method to monitor sucrose labeling is by nuclear magnetic resonance, which requires substantial amounts of biological sample.
Date: January 10, 2020
Creator: Cocuron, Jean-Christophe; Ross, Zacchary & Alonso, Ana P.
System: The UNT Digital Library
Does the left aorta provide proton-rich blood to the gut when crocodilians digest a meal? (open access)

Does the left aorta provide proton-rich blood to the gut when crocodilians digest a meal?

Article measuring blood parameters in the left aortae and atria of crocodilians. The findings do not support the hypothesis that a R–L shunt serves to deliver CO2 for the gastrointestinal system after feeding in crocodilians.
Date: February 4, 2019
Creator: Conner, Justin L.; Crossley, Janna; Elsey, Ruth M.; Nelson, Derek; Wang, Tobias & Crossley, Dane A., II
System: The UNT Digital Library
Larval Development in Tropical Gar (Atractosteus tropicus) Is Dependent on the Embryonic Thermal Regime: Ecological Implications under a Climate Change Context (open access)

Larval Development in Tropical Gar (Atractosteus tropicus) Is Dependent on the Embryonic Thermal Regime: Ecological Implications under a Climate Change Context

Article presents research on how temperature affects fish populations. The study shows how changes in temperature may induce craniofacial and morphological alterations in fish during early stages and contribute to understanding the possible effects of global warming in early development of fish and its ecological implications.
Date: December 14, 2021
Creator: Cordova-de la Cruz, Simrith E.; Riesco, Marta F.; Martínez-Bautista, Gil; Calzada-Ruiz, Daniel; Martínez-Burguete, Talhia; Peña-Marín, Emyr S. et al.
System: The UNT Digital Library
Silicon versus Superbug: Assessing Machine Learning's Role in the Fight against Antimicrobial Resistance (open access)

Silicon versus Superbug: Assessing Machine Learning's Role in the Fight against Antimicrobial Resistance

Article describes how, in his 1945 Nobel Prize acceptance speech, Sir Alexander Fleming warned of antimicrobial resistance (AMR) if the necessary precautions were not taken diligently. This paper explores the applications of ML in predicting and understanding AMR, highlighting its potential in revolutionizing healthcare practices.
Date: November 8, 2023
Creator: Coxe, Tallon & Azad, Rajeev K.
System: The UNT Digital Library
Draft Genome of the Common Snapping Turtle, Chelydra serpentina, a Model for Phenotypic Plasticity in Reptiles (open access)

Draft Genome of the Common Snapping Turtle, Chelydra serpentina, a Model for Phenotypic Plasticity in Reptiles

Article studying climate adaptation using common snapping turtles, Chelydra serpentina, as the model species. The genome and genetic variants identified here provide a foundation for future studies of adaptation to climate.
Date: December 1, 2020
Creator: Crossley, Dane A., II; Das, Debojyoti; Singh, Sunil Kumar; Bierstedt, Jacob; Erickson, Alyssa; Galli, Gina L. J. et al.
System: The UNT Digital Library
A novel benzimidazole derivative, MBIC inhibits tumor growth and promotes apoptosis via activation of ROS-dependent JNK signaling pathway in hepatocellular carcinoma (open access)

A novel benzimidazole derivative, MBIC inhibits tumor growth and promotes apoptosis via activation of ROS-dependent JNK signaling pathway in hepatocellular carcinoma

This study further explores a prior screening program carried out using MTT assay that identified a series of novel benzimidazole derivatives, among which Methyl 2-(5-fluoro-2-hydroxyphenyl)-1H-benzo[d]imidazole-5-carboxylate (MBIC) showed highest anticancer efficacy compared to that of chemotherapeutic agent, cisplatin. In this article, the authors find that MBIC inhibited cell viability in different hepatocellular carcinoma (HCC) cell lines without exerting significant cytotoxic effects on normal liver cells. The results of this study demonstrate that MBIC may inhibit cell proliferation via ROS-mediated activation of the JNK signaling cascade in HCC cells.
Date: January 12, 2017
Creator: Dai, Xiaoyun; Wang, Ling Zhi; Deivasigamni, Amudha; Looi, Chung Yeng; Karthikeyan, Chandrabose; Trivedi, Piyush et al.
System: The UNT Digital Library
Retinal oxygen supply shaped the functional evolution of the vertebrate eye (open access)

Retinal oxygen supply shaped the functional evolution of the vertebrate eye

Article explores the hypothesis that oxygen diffusion limited the evolution of retinal morphology by reconstructing the evolution of retinal thickness and the various mechanisms for retinal oxygen supply, including capillarization and acid-induced haemoglobin oxygen unloading.
Date: December 10, 2019
Creator: Damsgaard, Christian; Lauridsen, Henrik; Funder, Anette MD; Thomsen, Jesper S.; Desvignes, Thomas; Crossley, Dane A., II et al.
System: The UNT Digital Library
Exposure to diesel exhaust particles results in altered lung microbial profiles, associated with increased reactive oxygen species/reactive nitrogen species and inflammation, in C57Bl/6 wildtype mice on a high-fat diet (open access)

Exposure to diesel exhaust particles results in altered lung microbial profiles, associated with increased reactive oxygen species/reactive nitrogen species and inflammation, in C57Bl/6 wildtype mice on a high-fat diet

Article investigating if the exposure to diesel exhaust particles (DEP) can alter commensal lung microbiota, thereby promoting alterations in the lung’s immune and inflammatory responses. This article also explores if diet contributes to the alteration of the commensal lung microbiome.
Date: January 8, 2021
Creator: Daniel, Sarah; Phillippi, Danielle; Schneider, Leah J.; Nguyen, Kayla N.; Mirpuri, Julie & Lund, Amie K.
System: The UNT Digital Library