Resource Type

Epigenetic modulation of inflammation and synaptic plasticity promotes resilience against stress in mice (open access)

Epigenetic modulation of inflammation and synaptic plasticity promotes resilience against stress in mice

This article uses high-throughput screening to identify two phytochemicals that are effective in promoting resilience against stress by moduling brain synaptic plasticity and peripheral inflammation.
Date: September 7, 2016
Creator: Wang, Jun; Hodes, Georgia E.; Zhang, Hongxing; Zhang, Song; Zhao, Wei; Golden, Sam A. et al.
System: The UNT Digital Library
Gold Nanoparticles-enabled Efficient Dual Delivery of Anticancer Therapeutics to HeLa Cells (open access)

Gold Nanoparticles-enabled Efficient Dual Delivery of Anticancer Therapeutics to HeLa Cells

This article describes a facile one-step method to synthesize stable collodial gold nanoparticles (AuNPs) loaded with a combination of two anticancer therapeutics, -bleomycin and doxorubicin
Date: September 20, 2017
Creator: Farooq, Muhammad U.; Novosad, Valentyn; Rozhkova, Elena A.; Wali, Hussain; Ali, Asghar; Fateh, Ahmed A. et al.
System: The UNT Digital Library
Deciphering pathogenicity and antibiotic resistance islands in methicillin-resistant Staphylococcus aureus genomes (open access)

Deciphering pathogenicity and antibiotic resistance islands in methicillin-resistant Staphylococcus aureus genomes

This article explores the use of an information-entropy-based gene clustering method for genomic island detection in MRSA.
Date: November 16, 2017
Creator: Jani, Mehul; Sengupta, Soham; Hu, Kelsey & Azad, Rajeev K.
System: The UNT Digital Library
Computational design of environmental sensors for the potent opioid fentanyl (open access)

Computational design of environmental sensors for the potent opioid fentanyl

This article describes the computational design of proteins that bind the potent analgesic fentanyl.
Date: September 19, 2017
Creator: Bick, Matthew J.; Greisen, Per J.; Morey, Kevin J.; Antunes, Mauricio S.; La, David; Sankaran, Banumathi et al.
System: The UNT Digital Library
Multifeature analyses of vascular cambial cells reveal longevity mechanisms in old Ginkgo biloba trees (open access)

Multifeature analyses of vascular cambial cells reveal longevity mechanisms in old Ginkgo biloba trees

This article investigates age-related changes in Ginkgo biloba trees to learn more about the molecular and metabolic mechanisms underlying their longevity. The results revealed that long-lived trees have evolved compensatory mechanisms to maintain a balance between growth and aging processes.
Date: January 13, 2020
Creator: Wang, Li; Cui, Jiawen; Jin, Biao; Zhao, Jiangou; Xu, Huimin; Lu, Zhaogeng et al.
System: The UNT Digital Library
Evaluation of a Chicken 600K SNP genotyping array in non-model species of grouse (open access)

Evaluation of a Chicken 600K SNP genotyping array in non-model species of grouse

This article tested the cross-species application of the Affymetrix 600K Chicken SNP array in five species of North American prairie grouse (Centrocercus and Tympanuchus genera). This study study provided evidence for successful cross-species application of the chicken SNP array in grouse which diverged ca. 37 mya from the chicken lineage. As far as the authors are concerned, this is the first reported application of a SNP array in non-passerine birds, and it demonstrates the feasibility of using commercial SNP arrays in research on non-model bird species.
Date: October 19, 2018
Creator: Minias, Piotr; Dunn, Peter O.; Whittingham, Linda A.; Johnson, Jeff A. & Oyler-McCance, Sara
System: The UNT Digital Library
Phylogenetic analysis of the CDGSH iron-sulfur binding domain reveals its ancient origin (open access)

Phylogenetic analysis of the CDGSH iron-sulfur binding domain reveals its ancient origin

This article reports on the origin, evolution, and diversification of the iron-sulfur (2Fe-2S) binding motif CDGSH.
Date: November 28, 2017
Creator: Sengupta, Soham; Nechushtai, Rachel; Jennings, Patricia A.; Onuchic, José N.; Padilla, Pamela A.; Azad, Rajeev K. et al.
System: The UNT Digital Library
Identification of bottlenecks in the accumulation of cyclic fatty acids in camelina seed oil (open access)

Identification of bottlenecks in the accumulation of cyclic fatty acids in camelina seed oil

This article proposes a model for the accumulation of substantial levels of cyclopropane fatty acids (CPA) in camelina, and discusses the differences between CPA accumulation in camelina and Arabidopsis.
Date: July 10, 2017
Creator: Yu, Xiao-Hong; Cahoon, Rebecca E.; Horn, Patrick J.; Shi, Hai; Prakash, Richa R.; Cai, Yuanheng et al.
System: The UNT Digital Library
Effect of MS222 on Hemostasis in Zebrafish (open access)

Effect of MS222 on Hemostasis in Zebrafish

Article studying the effect of MS222 on hemostasis in Zebrafish. The authors performed various assays and find that Hct values, the amount of blood collected, bleeding, and coagulation differ significantly between anesthetized and nonanesthetized fish. These results suggest that blood collected after MS222 anesthesia of zebrafish has altered hemostasis.
Date: May 1, 2019
Creator: Afnan, Deebani; Iyer, Neha; Raman, Revathi & Jagadeeswaran, Pudur
System: The UNT Digital Library
Liquid Chromatography Tandem Mass Spectrometry Quantification of ¹³C-Labeling in Sugars (open access)

Liquid Chromatography Tandem Mass Spectrometry Quantification of ¹³C-Labeling in Sugars

This article describes a new methodology for monitoring sucrose labeling using liquid chromatography tandem mass spectrometry (LC-MS/MS). To date, the most commonly used method to monitor sucrose labeling is by nuclear magnetic resonance, which requires substantial amounts of biological sample.
Date: January 10, 2020
Creator: Cocuron, Jean-Christophe; Ross, Zacchary & Alonso, Ana P.
System: The UNT Digital Library
The Arabidopsis PAD4 Lipase-Like Domain Is Sufficient for Resistance to Green Peach Aphid (open access)

The Arabidopsis PAD4 Lipase-Like Domain Is Sufficient for Resistance to Green Peach Aphid

Article exploring PAD4 functions in plant defense by expressing the N-terminal PAD4 lipase-like domain (PAD4ᴸᴸᴰ) without its C-terminal EDS1-PAD4 (EP) domain. The authors show that transgenic expression of PAD4ᴸᴸᴰ in Arabidopsis is sufficient for limiting GPA infestation but not for conferring basal and effector-triggered pathogen immunity. This suggests that the C-terminal PAD4 EP domain is necessary for EDS1-dependent immune functions but is dispensable for aphid resistance. Moreover, PAD4ᴸᴸᴰ is not sufficient to interact with EDS1, indicating the PAD4-EP domain is required for stable heterodimerization. These data provide molecular evidence that PAD4 has domain-specific functions.
Date: December 27, 2019
Creator: Dongus, Joram A.; Bhandari, Deepak D.; Patel, Monika; Archer, Lani; Dijkgraaf, Lucas; Shah, Jyoti et al.
System: The UNT Digital Library
Opposing effects of MYZUS PERSICAE-INDUCED LIPASE 1 and jasmonic acid influence the outcome of Arabidopsis thaliana–Fusarium graminearum interaction (open access)

Opposing effects of MYZUS PERSICAE-INDUCED LIPASE 1 and jasmonic acid influence the outcome of Arabidopsis thaliana–Fusarium graminearum interaction

Article presents research that shows Arabidopsis MYZUS PERSICAE-INDUCED LIPASE 1 (MPL1), via its influence on limiting jasmonic acid (JA) accumulation, restricts Fusarium graminearum (Fg) infection.
Date: April 9, 2022
Creator: Alam, Syeda T.; Sarowar, Sujon; Mondal, Hossain A.; Makandar, Ragiba; Chowdhury, Zulkarnain; Louis, Joe et al.
System: The UNT Digital Library
Targeting the pattern-triggered immunity pathway to enhance resistance to Fusarium graminearum (open access)

Targeting the pattern-triggered immunity pathway to enhance resistance to Fusarium graminearum

Article describes study which shows that resistance against fusarium graminearum, the primary casual agent of fusarium head blight (FHB), can be enhanced by flg22, a bacterial microbe-associated molecular pattern (MAMP).
Date: February 6, 2019
Creator: Sarowar, Sujon; Alam, Syeda T.; Makandar, Ragiba; Lee, Hyeonju; Trick, Harold N.; Dong, Yanhong et al.
System: The UNT Digital Library
Environmental vibrios represent a source of antagonistic compounds that inhibit pathogenic Vibrio cholerae and Vibrio parahaemolyticus strains (open access)

Environmental vibrios represent a source of antagonistic compounds that inhibit pathogenic Vibrio cholerae and Vibrio parahaemolyticus strains

This article predicts that marine-derived bacteria should inhibit Vibrio pathogens and may be a source of unique antibiotic compounds.
Date: March 10, 2017
Creator: Burks, David J.; Norris, Stephen; Kauffman, Kathryn M.; Joy, Abigail; Arevalo, Philip; Azad, Rajeev K. et al.
System: The UNT Digital Library
A practical guide for assessing respiratory burst and phagocytic cell activity in the fathead minnow, an emerging model for immunotoxicity (open access)

A practical guide for assessing respiratory burst and phagocytic cell activity in the fathead minnow, an emerging model for immunotoxicity

Article is a study with the goal of optimizing and validating the use of a colorimetric plate-based respiratory burst and fluorometric plate-based phagocytic cell activity assays for use with kidney cells from the fathead minnow (Pimephales promelas), an emerging immunotoxicity model.
Date: July 18, 2020
Creator: Thornton Hampton, Leah M.; Venables, Barney J. & Jeffries, Marlo K. Sellin
System: The UNT Digital Library
Draft Genome Sequence of the Cyanotroph Pseudomonas monteilii BCN3 (open access)

Draft Genome Sequence of the Cyanotroph Pseudomonas monteilii BCN3

This article reports the first draft genome of Pseudomonas monteilii BCN3, a cyanotroph isolated from sewage sludge.
Date: January 3, 2019
Creator: Jones, Lauren B. & Kunz, Daniel A.
System: The UNT Digital Library
The future of legume genetic data resources: Challenges, opportunities, and priorities (open access)

The future of legume genetic data resources: Challenges, opportunities, and priorities

This article is a commentary on the future of legume genetic data resources and summarizes the workshop held in March of 2019 by the Legume Genomic Data Working Group that addressed questions of data resources and priorities for legumes.
Date: August 5, 2019
Creator: Legume Genomic Data Working Group
System: The UNT Digital Library
Analyzing Mass Spectrometry Imaging Data of 13C-Labeled Phospholipids in Camelina sativa and Thlaspi arvense (Pennycress) Embryos (open access)

Analyzing Mass Spectrometry Imaging Data of 13C-Labeled Phospholipids in Camelina sativa and Thlaspi arvense (Pennycress) Embryos

This article uses currently available software and techniques to describe a workflow to analyze ¹³C-labeled isotopologues of the membrane lipid and storage oil lipid intermediate—phosphatidylcholine (PC). Results demonstrated greater ¹³C-isotopic labeling in the cotyledons of developing embryos compared with the embryonic axis.
Date: March 4, 2021
Creator: Romsdahl, Trevor B.; Kambhampati, Shrikaar; Koley, Somnath; Yadav, Umesh P.; Alonso, Ana Paula; Allen, Doug K. et al.
System: The UNT Digital Library
Specific Changes in Arabidopsis thaliana Rosette Lipids during Freezing Can Be Associated with Freezing Tolerance (open access)

Specific Changes in Arabidopsis thaliana Rosette Lipids during Freezing Can Be Associated with Freezing Tolerance

This article explores the ability of Arabidopsis thaliana to recover after exposure to freezing temperatures.
Date: March 17, 2022
Creator: Vu, Hieu Sy; Shiva, Sunitha; Samarakoon, Thilani; Li, Maoyin; Sarowar, Sujon; Roth, Mary R. et al.
System: The UNT Digital Library
Targeted Metabolic Profiles of the Leaves and Xylem Sap of Two Sugarcane Genotypes Infected with the Vascular Bacterial Pathogen Leifsonia xyli subsp. xyli (open access)

Targeted Metabolic Profiles of the Leaves and Xylem Sap of Two Sugarcane Genotypes Infected with the Vascular Bacterial Pathogen Leifsonia xyli subsp. xyli

This article identifies discriminant metabolites between a resistant (R) and a susceptible (S) sugarcane variety at the early stages of pathogen colonization (30 and 120 days after inoculation—DAI) by untargeted and targeted metabolomics of leaves and xylem sap using gas chromatography-mass spectrometry (GC-MS) and liquid chromatography-tandem mass spectrometry (LC-MS/MS). The data represent a valuable resource of potential biomarkers for metabolite-assisted selection of resistant varieties to RS.
Date: April 12, 2021
Creator: Castro-Moretti, Fernanda R.; Cocuron, Jean-Christophe; Cia, Maria C.; Cataldi, Thais R.; Labate, Carlos A.; Alonso, Ana Paula et al.
System: The UNT Digital Library
Metabolomics as an Emerging Tool for the Study of Plant–Pathogen Interactions (open access)

Metabolomics as an Emerging Tool for the Study of Plant–Pathogen Interactions

Paper discusses metabolomics studies that link changes in primary or specialized metabolism to the defense responses of plants against bacterial, fungal, nematode, and viral pathogens.
Date: January 29, 2020
Creator: Castro-Moretti, Fernanda R.; Gentzel, Irene N.; Mackey, David & Alonso, Ana Paula
System: The UNT Digital Library
RNA helicase DP103 and TAK1: a new connection in cancer (open access)

RNA helicase DP103 and TAK1: a new connection in cancer

Article on new markers of tumor metastasis. The authors found that expression of DP103 was significantly upregulated in the metastatic basal subtype of breast cancers in 3 independent cohorts. This elevated DP103 expression correlated with metastatic breast cancer gene signatures and was strongly associated with patient survival. This study provides the first evidence that the RNA helicase DEAD-box protein DP103 is an NF-kB target that could form part of a positive feedback loop contributing to DP103- mediated regulation of TAK1 kinase activity on the major NF-kB kinase IKK2, thus implicating DP103 in the maintenance of this oncogenic signaling arm in human cancer.
Date: May 6, 2015
Creator: Shin, Eun Myoung; Osato, Motomi; Kumar, Alan Prem & Tergaonkar, Vinay
System: The UNT Digital Library
In situ cardiac performance of Atlantic cod (Gadus morhua) at cold temperatures: long-term acclimation, acute thermal challenge and the role of adrenaline (open access)

In situ cardiac performance of Atlantic cod (Gadus morhua) at cold temperatures: long-term acclimation, acute thermal challenge and the role of adrenaline

This article measures the cardiac performance of Newfoundland Atlantic cod (Gadus morhua). The results: (1) show that maximum performance of the isolated cod heart is not compromised by exposure to cold temperatures; and (2) support data from other studies, which show that, in contrast to salmonids, cod cardiac performance/myocardial contractility is not dependent upon humoral adrenergic stimulation.
Date: November 15, 2012
Creator: Lurman, Glenn J. & Petersen, L. H.
System: The UNT Digital Library
Acid-base regulation in the air-breathing swamp eel (Monopterus albus) at different temperatures (open access)

Acid-base regulation in the air-breathing swamp eel (Monopterus albus) at different temperatures

Article describes study in which researchers characterized the influence of temperature on arterial acid–base balance and intracellular pH (pHi) in the bimodal-breathing swamp eel, Monopterus albus.
Date: February 27, 2018
Creator: Thinh, Phan Vinh; Phuong, Nguyen Thanh; Brauner, Colin J.; Huong, Do Thi Thanh; Wood, Andrew T.; Kwan, Garfield T. et al.
System: The UNT Digital Library