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Regulators of von Willebrand Factor Levels (open access)

Regulators of von Willebrand Factor Levels

Data management plan for the grant "Regulators of von Willebrand Factor Levels." Von Willebrand Disease is the most prevalent bleeding disease. In one of the types called type 1 von Willebrand Disease, the disease-causing genes are not known. Using zebrafish as a model, this project proposes to identify genes that cause the disease by crippling the genes by knockdown methods, and such identification may lead to not only the identification of mutations in the corresponding human genes but also to a better diagnosis.
Date: 2021-08-01/2024-07-31
Creator: Jagadeeswaran, Pudur
System: The UNT Digital Library
MRI: Acquisition of a High Performance Hybrid Computer Cluster for Computational Modeling (open access)

MRI: Acquisition of a High Performance Hybrid Computer Cluster for Computational Modeling

Data management plan for the grant, "MRI: Acquisition of a High Performance Hybrid Computer Cluster for Computational Modeling." Research grant for the purchase, installation, and operation of a new high-performance computing (HPC) resource, called CRUNTCH4, to be deployed at the University of North Texas’ (UNT) Center for Advanced Scientific Computing and Modeling (CASCaM). This much needed HPC resource combines different computing architectures and significant amounts of data storage, all connected via a high-speed communications fabric. This computing resource will provide the means for CASCaM investigators to continue research on a broad range of topics including quantum chemistry, materials design, biomolecular simulations, machine-learning based chemical discovery, and bioinformatics, among others.
Date: 2021-10-01/2024-09-30
Creator: Cundari, Thomas R., 1964-; Du, Jincheng; Andreussi, Oliviero & Yan, Hao
System: The UNT Digital Library
Expanding A Bilingual Trauma-Based Behavioral Health Workforce in Integrated Health Settings (open access)

Expanding A Bilingual Trauma-Based Behavioral Health Workforce in Integrated Health Settings

Data management plan for the grant "Expanding A Bilingual Trauma-Based Behavioral Health Workforce in Integrated Health Settings."
Date: 2021-07-01/2022-06-30
Creator: Ceballos, Peggy; Carey, Chandra Donnell; Cartwright, Angie D. & Mukherjee, Dhrubodhi
System: The UNT Digital Library
Optimization for Thermal Protection of Firefighter’s Glove by Phase Change Material (open access)

Optimization for Thermal Protection of Firefighter’s Glove by Phase Change Material

Data management plan for the grant "Optimization for Thermal Protection of Firefighter’s Glove by Phase Change Material." Research project investigating improvements to firefighers gloves thermal protection.
Date: 2021-07-01/2023-06-30
Creator: Zhao, Weihuan
System: The UNT Digital Library
Non-Genetic Inheritance of Hypoxia Tolerance in Fishes: Dynamics and Mechanisms (open access)

Non-Genetic Inheritance of Hypoxia Tolerance in Fishes: Dynamics and Mechanisms

Data management plan for the grant, "Non-Genetic Inheritance of Hypoxia Tolerance in Fishes: Dynamics and Mechanisms." Research quantifying the inheritance of tolerance to low oxygen in a model fish and then determine the tolerance mechanisms, at organismal to molecular levels, that are passed on from parents to their offspring. The investigators will not only focus on conventional, well-studied genetic mechanisms for inheritance, but will explore so-called “epigenetic” forms of inheritance that may transfer parental characteristics for only a generation or two. Such “temporary inheritance” might actually require less energy and be more beneficial to a species than the more permanent form of genetic inheritance. This project will quantify non-genetic inheritance of hypoxia tolerance in zebrafish as a model organism and then identify underlying mechanisms, at organismal to molecular levels, in parents and in their progeny. Specifically, this project will quantify non-genetically inherited traits that allow hypoxia tolerance, determine “wash-in” and “wash-out” (i.e., the dynamics) of hypoxia-tolerant phenotypes across multiple generations, and establish epigenetic mechanism(s) of non-genetic inheritance in subsequent generations. The information provided by this project will allow biologists to better predict, and perhaps even mitigate, the negative consequences of future episodes of low oxygen in rivers and lakes.
Date: 2021-06-15/2025-05-31
Creator: Burggren, Warren W. & Padilla, Pamela A.
System: The UNT Digital Library
Chemical-Guided Identification of Primary Metabolic Targets for Improvement of Hydroxy Fatty Acid Synthesis in Physaria fendleri (open access)

Chemical-Guided Identification of Primary Metabolic Targets for Improvement of Hydroxy Fatty Acid Synthesis in Physaria fendleri

Data management plan for the grant, "Chemical-Guided Identification of Primary Metabolic Targets for Improvement of Hydroxy Fatty Acid Synthesis in Physaria fendleri." Research on the identification of primary metabolic targets using chemical-guided identification. The first objective of this research is to conduct metabolomics analysis on P. fendleri embryos cultured with two identified chemical regulators of fatty acid metabolism. The second objective of this research is to generate a metabolic flux map of embryos treated with these regulatory compounds in order to determine how metabolic rates and carbon flow can be manipulated to improve HFA production in this species and increase its commercial viability. With properties that could replace imported castor oil, research on the crop in discussion is situated directly in the scope of the USDA-AFRI Education and Workforce Development goals.
Date: 2021-06-15/2023-06-14
Creator: Johnston, Christopher
System: The UNT Digital Library
Metal Oxynitrides: Tuning Metal-N and Metal-O Interactions for Improved Electrocatalytic Properties at the Liquid/Solid Interface (open access)

Metal Oxynitrides: Tuning Metal-N and Metal-O Interactions for Improved Electrocatalytic Properties at the Liquid/Solid Interface

Data management plan for the grant "Metal Oxynitrides: Tuning Metal-N and Metal-O Interactions for Improved Electrocatalytic Properties at the Liquid/Solid Interface." Research investigating the fundamental chemical interactions relevant to the conversion of dinitrogen to ammonia via more energy-efficient routes. The studies will help in understanding the chemical and material factors that are most important for optimizing new materials for ammonia production from dinitrogen, and applications to other important industrial reactions.
Date: 2021-08-01/2024-07-31
Creator: Kelber, Jeffry A.; Cundari, Thomas R., 1964- & D'Souza, Francis
System: The UNT Digital Library
Metal Organic Frameworks Containing Frustrated Lewis Pairs for Hydrogen Storage at Ambient Temperature (open access)

Metal Organic Frameworks Containing Frustrated Lewis Pairs for Hydrogen Storage at Ambient Temperature

Data Management Plan for the research project: Metal Organic Frameworks Containing Frustrated Lewis Pairs for Hydrogen Storage at Ambient Temperature. Research to design, synthesize, and characterize novel sorbent materials for hydrogen storage. The materials are based on a Metal-Organic Framework and incorporate Frustrated Lewis Pairs (FLP-MOF). The project seeks to optimize the hydrogen storage capacity of the FLP-MOF systems at ambient temperature and under high pressure.
Date: 2021-07-01/2024-06-30
Creator: Ma, Shengqian
System: The UNT Digital Library
Connecting Galaxies and Supermassive Black Holes: Meso-scale Simulations of Multiphase Accretion Flows (open access)

Connecting Galaxies and Supermassive Black Holes: Meso-scale Simulations of Multiphase Accretion Flows

Data management plan for the grant, "Connecting Galaxies and Supermassive Black Holes: Meso-scale Simulations of Multiphase Accretion Flows." It proposes to study how gas flows onto the supermassive black holes in massive galaxies and galaxy clusters. They will perform numerical simulations with a nested zoom-in technique, focusing on the mesoscale accretion flows from the Bondi radius to hundreds of Schwarzschild radii. They will predict the mass flux of different phases, as well as their angular momentum and magnetic flux.
Date: 2022-07-01/2025-06-30
Creator: Li, Yuan
System: The UNT Digital Library
Using uncertainty quantification and machine learning techniques to study the evolution of odor capture (open access)

Using uncertainty quantification and machine learning techniques to study the evolution of odor capture

Data management plan for the research grant, "Using uncertainty quantification and machine learning techniques to study the evolution of odor capture." This research proposes the application of uncertainty quantification (UQ) and machine learning (ML) to a CFD model of odor capture to understand the role of hair-array morphology, kinematics, and fluid environment in odor capture. The combination of CFD modeling and UQ&ML techniques can map out the performance space under which these chemosensory hair arrays operate and the relative sensitivity of each parameter of odor capture to construct a global, quantitative understanding of how parameters control odor-capture performance. Furthermore, this analysis can eliminate parameters that have no influence on odor capture, extracting the root principles of odor capture and providing a more efficient way to construct bioinspired devices for chemical detection. This work is of interest to the Army for extracting design principles that can be used for biomimetic and/or bioinspired devices for sensing hazardous chemicals in the environment (e.g. explosives).
Date: 2022-04-01/2025-03-31
Creator: He, Yanyan & Waldrop, Lindsay D.
System: The UNT Digital Library
Analyzing existing support structures for transfer students in Chemistry between the University of North Texas and Dallas College (open access)

Analyzing existing support structures for transfer students in Chemistry between the University of North Texas and Dallas College

Data management plan for a grant seeking to analyze existing support structures for transfer students in Chemistry between the University of North Texas and Dallas College.
Date: 2022-12-01/2023-11-30
Creator: Atkinson, Molly B.
System: The UNT Digital Library
Southwest Local Algebra Meeting 2023 (open access)

Southwest Local Algebra Meeting 2023

Data management plan for the grant, "Southwest Local Algebra Meeting 2023." No data will be collected or reported for this grant.
Date: 2023-01-15/2023-12-31
Creator: Conley, Charles H.
System: The UNT Digital Library
Quantitative PCR Primer Development for Early Detection of Invasive Species (open access)

Quantitative PCR Primer Development for Early Detection of Invasive Species

Data management plan for the grant, "Quantitative PCR Primer Development for Early Detection of Invasive Species."
Date: 2023-09-01/2026-08-31
Creator: Compson, Zacchaeus Greg
System: The UNT Digital Library
A Laser Microdissection System to Enhance Agricultural and Food Research in the North Texas and Southern Oklahoma Region (open access)

A Laser Microdissection System to Enhance Agricultural and Food Research in the North Texas and Southern Oklahoma Region

Data management plan for the grant, "A Laser Microdissection System to Enhance Agricultural and Food Research in the North Texas and Southern Oklahoma Region."
Date: 2023-09-01/2027-08-31
Creator: Ayre, Brian G.
System: The UNT Digital Library
Exploring thermal properties of nanoscale wide bandgap semiconductors via  ultrafast thermal-emission spectroscopy (open access)

Exploring thermal properties of nanoscale wide bandgap semiconductors via ultrafast thermal-emission spectroscopy

Data management plan for the grant, "Exploring thermal properties of nanoscale wide bandgap semiconductors via ultrafast thermal-emission spectroscopy." In this project, we aim to develop a new thermometrology technique based on ultrafast thermal emission to directly and accurately measure thermal properties of thin-film wide bandgap semiconductors.
Date: 2023-09-30/2025-09-29
Creator: Xiao, Yuzhe
System: The UNT Digital Library
The Molecular Building Block Sampling Approach for Polymorphic Free Energy Calculations (open access)

The Molecular Building Block Sampling Approach for Polymorphic Free Energy Calculations

Data management plan for the grant, "The Molecular Building Block Sampling Approach for Polymorphic Free Energy Calculations."
Date: 2023-07-01/2024-06-30
Creator: Valsson, Omar
System: The UNT Digital Library
Complexity Synchronization: Information Transmission among Complex Systems (open access)

Complexity Synchronization: Information Transmission among Complex Systems

Data management plan for the grant, "Complexity Synchronization: Information Transmission among Complex Systems."
Date: 2023-09-29/2024-09-28
Creator: Grigolini, Paolo
System: The UNT Digital Library
Graduate Research Fellowship Program (GRFP): Landscape genetics of wild turkey (Meleagris gallopavo) in Texas (open access)

Graduate Research Fellowship Program (GRFP): Landscape genetics of wild turkey (Meleagris gallopavo) in Texas

Data management plan for the grant, "Graduate Research Fellowship Program (GRFP): Landscape genetics of wild turkey (Meleagris gallopavo) in Texas."
Date: 2023-09-15/2028-08-31
Creator: Gregory, Andrew & Molina, Clarissa
System: The UNT Digital Library
Examining the Viability of the use of Sarocladium zeae as a Biocontrol Agent in the Agricultural Production of Maize (open access)

Examining the Viability of the use of Sarocladium zeae as a Biocontrol Agent in the Agricultural Production of Maize

Data management plan for the grant, "Examining the Viability of the use of Sarocladium zeae as a Biocontrol Agent in the Agricultural Production of Maize." Sarocladium zeae is a fungus that naturally grows within corn and produces pyrrocidines, compounds that inhibit the production of two exogenous threats to maize, aflatoxins and fumonisins. This project aims to identify other natural products that may be produced by S. zeae through genetic modification in native and non-native fungal hosts to ensure there are no toxins present. In doing so, further information will be gathered about the possibility of using S. zeae as a targeted biocontrol agent that protects against exogenous threats while remaining safe for consumption.
Date: 2023-06-01/2026-05-31
Creator: Skellam, Elizabeth & Schoellhorn, Sydney
System: The UNT Digital Library
Approximation Theory and Complex Dynamics (open access)

Approximation Theory and Complex Dynamics

Data management plan for the grant, "Approximation Theory and Complex Dynamics." This project involves the study of approximation theory in the setting of complex functions, with applications to complex dynamics. Approximation theory seeks to understand the extent to which the behavior of a general function can be effectively modeled by that of functions drawn from a more restricted class. Efficient approximation of functions is of relevance for numerical calculation. Since the only calculations that can be carried out numerically are the elementary operations of addition, subtraction, multiplication, and division, in practical terms it is of importance to understand when the values of general functions are well approximated by the values of either polynomial or rational functions. In many situations, the values of the approximant resemble those of the general function only for a sampling of input values. What can be said about values of the approximant for other choices of input? This is the main question studied in this project, with the following application in mind: when a general function is iterated to produce a dynamical system, to what extent does the dynamical behavior of an approximant resemble the dynamical behavior of the original function? The project will also contribute …
Date: 2023-09-01/2026-08-31
Creator: Lazebnik, Kirill
System: The UNT Digital Library
Structural and mechanistic studies of oxalate catabolism (open access)

Structural and mechanistic studies of oxalate catabolism

Data management plan for the grant, "Structural and mechanistic studies of oxalate catabolism." Biologically derived oxalic acid has been shown to have a negative impact on crop production and human health. Oxalate present in plant foods can decrease their nutritional value by binding to calcium and rendering that calcium unavailable for nutritional absorption. This project will study the structure and function of key enzymes in oxalate turnover to understand their biological functions and mechanisms, facilitating metabolic engineering of plants toward improving nutritional quality and production of plant derived foods.
Date: 2023-06-15/2026-05-31
Creator: Wang, Xiaoqiang
System: The UNT Digital Library
Novel regulators of Slo2 potassium channels (open access)

Novel regulators of Slo2 potassium channels

Data management plan for the grant, "Novel regulators of Slo2 potassium channels"
Date: 2024-02-15/2026-01-31
Creator: Chen, Bojun
System: The UNT Digital Library
CAREER: Liquid Crystal-Templated Sequential Infiltration Synthesis of Hybrid Organic/Inorganic Materials with Multidimensional Chiral Structures (open access)

CAREER: Liquid Crystal-Templated Sequential Infiltration Synthesis of Hybrid Organic/Inorganic Materials with Multidimensional Chiral Structures

Data management plan for the grant, "CAREER: Liquid Crystal-Templated Sequential Infiltration Synthesis of Hybrid Organic/Inorganic Materials with Multidimensional Chiral Structures"
Date: 2024-03-01/2029-02-28
Creator: Li, Xiao
System: The UNT Digital Library
CAREER: Modeling the Evolution of Massive Galaxies with Enzo-E (open access)

CAREER: Modeling the Evolution of Massive Galaxies with Enzo-E

Data management plan for the grant, "CAREER: Modeling the Evolution of Massive Galaxies with Enzo-E."
Date: 2024-09-01/2029-08-31
Creator: Li, Yuan
System: The UNT Digital Library