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Fatty Acid Amide Hydrolases and Chemical Communication in Plants (open access)

Fatty Acid Amide Hydrolases and Chemical Communication in Plants

Data management plan for the grant, "Fatty Acid Amide Hydrolases and Chemical Communication in Plants." Research seeking to understand how an evolutionarily-conserved group of plant enzymes utilizes chemical signals to regulate growth and to influence their microbial environment. Specific research aims include the discovery of new enzymes and their substrate molecules that act as communication signals. Broader applications of this research may offer new strategies to enhance agricultural outputs by manipulating plant-microbe interactions in crop and soil systems.
Date: 2021-07-01/2024-06-30
Creator: Chapman, Kent Dean; Aziz, Mina & Blancaflor, Elison B.
System: The UNT Digital Library
IRES Track II - Cape Horn ASIs: Climate change and disease ecology at the southern end of the Americas (open access)

IRES Track II - Cape Horn ASIs: Climate change and disease ecology at the southern end of the Americas

Data management plan for the grant "IRES Track II - Cape Horn ASIs: Climate change and disease ecology at the southern end of the Americas." Research giving students the opportunity to be trained in quantitative experimental design and work as part of a multinational research collaboration to study infectious disease emergence in one of the few remaining pristine places on Earth. The Cape Horn Biosphere Reserve (CHBR) off the southern tip of South America protects pristine ecosystem is perfect for this type of graduate student training. The CHBR is part of the sub-Antarctic Magellanic ecoregion, which is globally significant because it houses the worlds southernmost forest biome, contains numerous endemic species, is remote, and is relatively free of anthropogenic impacts. The research questions themselves will be flexible, but organized thematically. Specifically, this IRES Track-II will focus on the merging molecular genetic analysis using a mobile next generation sequencing lab with mist netting and arthropod trapping to investigate the impacts of wildlife disease on local biodiversity and community structure. Secondarily, eDNA and traditional wildlife disease monitoring approaches will be applied to understand the potential for zoonosis and understanding ecological factors that contribute to, or inhibit, zoonosis. Resultantly, participation in this program …
Date: 2021-09-01/2024-08-31
Creator: Gregory, Andrew; Kennedy, James H. & Rozzi, Ricardo, 1960-
System: The UNT Digital Library
Collaborative Research: PIC: Slow Wave Enhanced Electrooptically Tuned Michelson Interferometer Biosensor for On-Chip Polarization Interferometry (open access)

Collaborative Research: PIC: Slow Wave Enhanced Electrooptically Tuned Michelson Interferometer Biosensor for On-Chip Polarization Interferometry

Data management plan for the grant, "Collaborative Research: PIC: Slow Wave Enhanced Electrooptically Tuned Michelson Interferometer Biosensor for On-Chip Polarization Interferometry."
Date: 2022-09-01/2025-08-31
Creator: Rout, Bibhudutta
System: The UNT Digital Library
Low-Energy Atomic Processes Including Ones Involving a Positron (open access)

Low-Energy Atomic Processes Including Ones Involving a Positron

Data management plan for the grant, "Low-Energy Atomic Processes Including Ones Involving a Positron." The proposed research in theoretical atomic physics involves few-body systems of charged particles, especially ones that involve the antiparticle of the electron, which is a positron. One of these systems is the positronium negative ion, which is comprised of two electrons and a positron. The exotic positronium atom is similar to the conventional hydrogen atom, but the positive charge in the atom is a positron rather than a proton. The proposed studies of these few-body charged systems will support international collaborations with scientists in the UK and Japan.
Date: 2022-09-01/2025-08-31
Creator: Quintanilla, Sandra J.
System: The UNT Digital Library
Development of advanced biocatalyst tools and resources to enable biogas-based biomanufacturing (open access)

Development of advanced biocatalyst tools and resources to enable biogas-based biomanufacturing

Data management plan for the grant, "Development of advanced biocatalyst tools and resources to enable biogas-based biomanufacturing."
Date: 2022-08-15/2025-07-31
Creator: Henard, Calvin
System: The UNT Digital Library
Encapsulated perovskite in NiO nanotube for topological meta-photonic devices (open access)

Encapsulated perovskite in NiO nanotube for topological meta-photonic devices

Data management plan for the grant, "Encapsulated perovskite in NiO nanotube for topological meta-photonic devices." Research studying meta-photonic devices with high absorption and topological photonic devices using encapsulated perovskites in NiO nanotubes. The goal is to achieve high-efficiency solar cells and electrically pumped laser in perovskite/NiO nanotubes patterned in the graded photonic super-crystal. The success of this project will lead to high-efficiency integrated lasers and solar cell devices. It also enhances the abilities in the education arena by enriching program offerings in nanotechnology, clean-energy, and photonics technology.
Date: 2021-09-01/2024-08-31
Creator: Cui, Jingbiao & Lin, Yuankun
System: The UNT Digital Library
Collaborative Research: A Systematic and Comprehensive Study of Black Hole-Driven Turbulence in Massive Galactic Systems (open access)

Collaborative Research: A Systematic and Comprehensive Study of Black Hole-Driven Turbulence in Massive Galactic Systems

Data management plan for the grant, "Collaborative Research: A Systematic and Comprehensive Study of Black Hole-Driven Turbulence in Massive Galactic Systems." This research team has developed a technique to measure gas turbulence in systems hosting giant central black holes and will directly evaluate the viability of this mechanism using a large sample of galaxies. This project will deliver a more complete view of the “feedback” provided by accreting SMBHs, leading to a better understanding of the black hole-host galaxy relation. More specifically, it will directly probe the energetics of the intra-cluster, circum-galactic, and interstellar media of massive early-type galaxies.
Date: 2021-09-01/2024-08-31
Creator: Li, Yuan
System: The UNT Digital Library
Development of Novel Approaches to Earth-abundant Methane Catalysis (open access)

Development of Novel Approaches to Earth-abundant Methane Catalysis

Data management plan for the grant "Development of Novel Approaches to Earth-abundant Methane Catalysis." Research on catalytic cycles for C–H activation and functionalization of light alkanes based on the CMD (concerted metalation deprotonation) mechanism will be modeled for Earth-abundant metal dicarboxylates and related complexes. The impact of inner and outer coordination sphere effects upon catalytic cycles for light alkane functionalization will be assessed using computational chemistry techniques. The aforementioned studies will be leveraged to identify promising, synthetically feasible lead catalysts for experimental collaborators.
Date: 2021-08-15/2024-08-14
Creator: Cundari, Thomas R., 1964-
System: The UNT Digital Library
NSFDEB-NERC: Collaborative Research: Wildlife corridors: do they work and who benefits? (open access)

NSFDEB-NERC: Collaborative Research: Wildlife corridors: do they work and who benefits?

Data management plan for the grant, "NSFDEB-NERC: Collaborative Research: Wildlife corridors: do they work and who benefits?" Research on the impact of wildlife corridors using genetics as the measure of effectiveness. The study will use 20 independent landscapes to quantify how corridor traits affect gene flow, and will use non-flying mammals as focal species because they are strongly affected by fragmentation. The research team hypothesizes (1) a strong non-linear decline in success (gene flow) with corridor length, reflecting the skewed distribution of dispersal distances within species; (2) success will drop steeply as corridor width falls below a threshold, with the threshold determined by species traits; and (3) species that are bigger, are habitat specialists, or have greater dispersal abilities (relative to brain size or reproductive rate) will benefit more from corridors. Testing these hypotheses will allow generalization to a wide range of mammal species not included in this project. It will use highly flexible Random Forest models to answer the overarching question: What landscape traits (e.g., corridor width, degree of human disturbance) and species traits (mobility, affinity to particular land cover types) are associated with effective corridors?
Date: 2021-01-15/2023-12-31
Creator: Gregory, Andrew
System: The UNT Digital Library
Developing a Biomanufacturing Platform for the Site-Selective Functionalization and Structural Diversification of Cytochalasan-Based Carbon Skeletons (open access)

Developing a Biomanufacturing Platform for the Site-Selective Functionalization and Structural Diversification of Cytochalasan-Based Carbon Skeletons

Data management plan for the grant, "Developing a Biomanufacturing Platform for the Site-Selective Functionalization and Structural Diversification of Cytochalasan-Based Carbon Skeletons." This project will identify fungal enzymes that efficiently modify more than one substrate in a predictable way. Also, enzymes will be engineered to expand the range of substrates. A biomanufacturing platform to synthesize bioactive molecules at lower costs will be the end result. Fungi can synthesize small molecules with complex structures using a number of highly coordinated enzymes. These molecules are difficult to make synthetically, and they can aid in crop production or have beneficial human health effects. Cytochalasans are phytotoxic, cytotoxic and actin-binding natural products. Produced by fungi, over 400 variants have been described. The structural diversity is partly explained by the flexibility of the enzymes that introduce and modify functional groups. These enzymes structurally rearrange the core carbon skeleton in a site-selective manner, often on more than one substrate. Genome mining will be used to identify cytochalasan tailoring enzymes. Overproducing strains will be characterized chemically. Transcription factor over-expression will be investigated. Targeted gene knock-out will confirm the function and scope of the enzymes. The enzymes will be engineered to expand their substrate range. Synthetic biology and metabolic …
Date: 2021-03-01/2024-02-29
Creator: Skellam, Elizabeth
System: The UNT Digital Library
G-RISE at the University of North Texas (open access)

G-RISE at the University of North Texas

Data management plan for the grant "G-RISE at the University of North Texas." The University of North Texas (UNT) serves over 32,000 undergraduate and 7,000 graduate students of which 50% of the undergraduate population and 20% of the graduate population are underrepresented minority (URM). UNT is ranked by the Carnegie Classification as a Tier 1 institute, is a Hispanic Serving Institute, and is dedicated to providing quality mentoring to a diverse group of Ph.D. students. The UNT G-­RISE mission is to provide a biomedical Ph.D. training program that is inclusive, culturally responsive, increases diversity, enhances scientific skill sets, develops trainee career and professional skill sets, provides opportunities to participants, and increases faculty development as a mentor.
Date: 2021-05-01/2022-04-30
Creator: Padilla, Pamela A.; Burggren, Warren W.; Cisneros, Gerardo Andrés & Hughes, Lee E.
System: The UNT Digital Library
Collaborative Research: Using Uncertainty Quantification and Validated Computational Models to Analyze Pumping Performance of Valveless, Tubular Hearts (open access)

Collaborative Research: Using Uncertainty Quantification and Validated Computational Models to Analyze Pumping Performance of Valveless, Tubular Hearts

Data management plan for the research grant, "Collaborative Research: Using Uncertainty Quantification and Validated Computational Models to Analyze Pumping Performance of Valveless, Tubular Hearts." This project will develop a computational model of the essential features of the circulatory system: the electrical activity of the heart, muscle contractions of the tube walls, and the fluid-structure interactions of the heart walls and blood within. This computational framework aims to be faithful to that of a real, model animal (tunicate, or sea squirt). The model will then be analyzed with mathematical tools to determine the physical limits of the pumping system. Results of this project will improve the understanding of human heart development at the earliest stages. Also, it will point to how the large, multi-chambered hearts of vertebrates could have evolved from smaller structures.
Date: 2022-05-01/2025-04-30
Creator: He, Yanyan & Cain, John
System: The UNT Digital Library
Building a Team for EXtragalactic AStrophysics (TEXAS) in the Dallas-Fort Worth Metroplex (open access)

Building a Team for EXtragalactic AStrophysics (TEXAS) in the Dallas-Fort Worth Metroplex

Data management plan for the grant, "Building a Team for EXtragalactic AStrophysics (TEXAS) in the Dallas-Fort Worth Metroplex". The project will build a new partnership between the University of North Texas (UNT), an R1 Minority-Serving Institution (MSI)/ Hispanic-Serving Institution (HSI), and the University of Texas at Dallas (UTD). During the pilot phase, the team will establish a post-baccalaureate bridge program and organize monthly colloquia and annual symposia to broaden the participation of underrepresented groups in astronomy.
Date: 2022-09-01/2024-08-31
Creator: Li, Yuan
System: The UNT Digital Library
Functional Porous Organic Polymers as Advanced Decontamination Materials for Water Purification (open access)

Functional Porous Organic Polymers as Advanced Decontamination Materials for Water Purification

Data management plan for the grant "Functional Porous Organic Polymers as Advanced Decontamination Materials for Water Purification." This project seeks to develop and deploy a new class of porous organic polymers which have high capacity and selectivity to rapidly remove heavy metal contaminants well below parts per million level standards set by the Environmental Protection Agency. The project will engineer porosity and surface chemistry of porous organic polymers to clean inorganic heavy metal contaminants from both surface water and wastewater. Porous organic polymers are robust, chemically and thermally stable, scalable, and modular, with very high surface area. The modularity of these polymers allows for a molecular-level tuning of the pore structure and surface chemistry that allows for engineered site-specificity of binding sites that target the heavy metal contaminants. Recent data shows these new materials offer a significant increase in capacity relative to benchmark materials, with a rapid removal of mercury and other heavy metal ions. This project will advance the concept by exploring rational design of these porous polymers with different topologies by customizing the monomer with various binding groups. The objectives of the project include design, synthesis, and characterization, followed by assessment of these materials to remove inorganic contaminants …
Date: 2021-02-01/2021-07-31
Creator: Ma, Shengqian
System: The UNT Digital Library
Generating pathogen- / pest-resistant non-GMO cotton through targeted genome editing of oxylipin signaling pathways (open access)

Generating pathogen- / pest-resistant non-GMO cotton through targeted genome editing of oxylipin signaling pathways

Data management plan for the research grant "Generating pathogen- / pest-resistant non-GMO cotton through targeted genome editing of oxylipin signaling pathways."
Date: 2021-01-15/2024-01-14
Creator: Ayre, Brian G.; McGarry, Roisin C. & Shah, Jyoti
System: The UNT Digital Library
LLELA Quail Program: Quail in the Park Cities? Restoring a functional quail population to a small rangeland system in the Dallas Metroplex (open access)

LLELA Quail Program: Quail in the Park Cities? Restoring a functional quail population to a small rangeland system in the Dallas Metroplex

Data management plan for the grant, "LLELA Quail Program: Quail in the Park Cities? Restoring a functional quail population to a small rangeland system in the Dallas Metroplex."
Date: 2021-10-01/2022-09-30
Creator: Gregory, Andrew
System: The UNT Digital Library
Regulators of von Willebrand Factor Levels (open access)

Regulators of von Willebrand Factor Levels

Data management plan for the grant "Regulators of von Willebrand Factor Levels." Von Willebrand Disease is the most prevalent bleeding disease. In one of the types called type 1 von Willebrand Disease, the disease-causing genes are not known. Using zebrafish as a model, this project proposes to identify genes that cause the disease by crippling the genes by knockdown methods, and such identification may lead to not only the identification of mutations in the corresponding human genes but also to a better diagnosis.
Date: 2021-08-01/2024-07-31
Creator: Jagadeeswaran, Pudur
System: The UNT Digital Library
MRI: Acquisition of a High Performance Hybrid Computer Cluster for Computational Modeling (open access)

MRI: Acquisition of a High Performance Hybrid Computer Cluster for Computational Modeling

Data management plan for the grant, "MRI: Acquisition of a High Performance Hybrid Computer Cluster for Computational Modeling." Research grant for the purchase, installation, and operation of a new high-performance computing (HPC) resource, called CRUNTCH4, to be deployed at the University of North Texas’ (UNT) Center for Advanced Scientific Computing and Modeling (CASCaM). This much needed HPC resource combines different computing architectures and significant amounts of data storage, all connected via a high-speed communications fabric. This computing resource will provide the means for CASCaM investigators to continue research on a broad range of topics including quantum chemistry, materials design, biomolecular simulations, machine-learning based chemical discovery, and bioinformatics, among others.
Date: 2021-10-01/2024-09-30
Creator: Cundari, Thomas R., 1964-; Du, Jincheng; Andreussi, Oliviero & Yan, Hao
System: The UNT Digital Library
Expanding A Bilingual Trauma-Based Behavioral Health Workforce in Integrated Health Settings (open access)

Expanding A Bilingual Trauma-Based Behavioral Health Workforce in Integrated Health Settings

Data management plan for the grant "Expanding A Bilingual Trauma-Based Behavioral Health Workforce in Integrated Health Settings."
Date: 2021-07-01/2022-06-30
Creator: Ceballos, Peggy; Carey, Chandra Donnell; Cartwright, Angie D. & Mukherjee, Dhrubodhi
System: The UNT Digital Library
Optimization for Thermal Protection of Firefighter’s Glove by Phase Change Material (open access)

Optimization for Thermal Protection of Firefighter’s Glove by Phase Change Material

Data management plan for the grant "Optimization for Thermal Protection of Firefighter’s Glove by Phase Change Material." Research project investigating improvements to firefighers gloves thermal protection.
Date: 2021-07-01/2023-06-30
Creator: Zhao, Weihuan
System: The UNT Digital Library
Non-Genetic Inheritance of Hypoxia Tolerance in Fishes: Dynamics and Mechanisms (open access)

Non-Genetic Inheritance of Hypoxia Tolerance in Fishes: Dynamics and Mechanisms

Data management plan for the grant, "Non-Genetic Inheritance of Hypoxia Tolerance in Fishes: Dynamics and Mechanisms." Research quantifying the inheritance of tolerance to low oxygen in a model fish and then determine the tolerance mechanisms, at organismal to molecular levels, that are passed on from parents to their offspring. The investigators will not only focus on conventional, well-studied genetic mechanisms for inheritance, but will explore so-called “epigenetic” forms of inheritance that may transfer parental characteristics for only a generation or two. Such “temporary inheritance” might actually require less energy and be more beneficial to a species than the more permanent form of genetic inheritance. This project will quantify non-genetic inheritance of hypoxia tolerance in zebrafish as a model organism and then identify underlying mechanisms, at organismal to molecular levels, in parents and in their progeny. Specifically, this project will quantify non-genetically inherited traits that allow hypoxia tolerance, determine “wash-in” and “wash-out” (i.e., the dynamics) of hypoxia-tolerant phenotypes across multiple generations, and establish epigenetic mechanism(s) of non-genetic inheritance in subsequent generations. The information provided by this project will allow biologists to better predict, and perhaps even mitigate, the negative consequences of future episodes of low oxygen in rivers and lakes.
Date: 2021-06-15/2025-05-31
Creator: Burggren, Warren W. & Padilla, Pamela A.
System: The UNT Digital Library
Chemical-Guided Identification of Primary Metabolic Targets for Improvement of Hydroxy Fatty Acid Synthesis in Physaria fendleri (open access)

Chemical-Guided Identification of Primary Metabolic Targets for Improvement of Hydroxy Fatty Acid Synthesis in Physaria fendleri

Data management plan for the grant, "Chemical-Guided Identification of Primary Metabolic Targets for Improvement of Hydroxy Fatty Acid Synthesis in Physaria fendleri." Research on the identification of primary metabolic targets using chemical-guided identification. The first objective of this research is to conduct metabolomics analysis on P. fendleri embryos cultured with two identified chemical regulators of fatty acid metabolism. The second objective of this research is to generate a metabolic flux map of embryos treated with these regulatory compounds in order to determine how metabolic rates and carbon flow can be manipulated to improve HFA production in this species and increase its commercial viability. With properties that could replace imported castor oil, research on the crop in discussion is situated directly in the scope of the USDA-AFRI Education and Workforce Development goals.
Date: 2021-06-15/2023-06-14
Creator: Johnston, Christopher
System: The UNT Digital Library
Metal Oxynitrides: Tuning Metal-N and Metal-O Interactions for Improved Electrocatalytic Properties at the Liquid/Solid Interface (open access)

Metal Oxynitrides: Tuning Metal-N and Metal-O Interactions for Improved Electrocatalytic Properties at the Liquid/Solid Interface

Data management plan for the grant "Metal Oxynitrides: Tuning Metal-N and Metal-O Interactions for Improved Electrocatalytic Properties at the Liquid/Solid Interface." Research investigating the fundamental chemical interactions relevant to the conversion of dinitrogen to ammonia via more energy-efficient routes. The studies will help in understanding the chemical and material factors that are most important for optimizing new materials for ammonia production from dinitrogen, and applications to other important industrial reactions.
Date: 2021-08-01/2024-07-31
Creator: Kelber, Jeffry A.; Cundari, Thomas R., 1964- & D'Souza, Francis
System: The UNT Digital Library
Metal Organic Frameworks Containing Frustrated Lewis Pairs for Hydrogen Storage at Ambient Temperature (open access)

Metal Organic Frameworks Containing Frustrated Lewis Pairs for Hydrogen Storage at Ambient Temperature

Data Management Plan for the research project: Metal Organic Frameworks Containing Frustrated Lewis Pairs for Hydrogen Storage at Ambient Temperature. Research to design, synthesize, and characterize novel sorbent materials for hydrogen storage. The materials are based on a Metal-Organic Framework and incorporate Frustrated Lewis Pairs (FLP-MOF). The project seeks to optimize the hydrogen storage capacity of the FLP-MOF systems at ambient temperature and under high pressure.
Date: 2021-07-01/2024-06-30
Creator: Ma, Shengqian
System: The UNT Digital Library