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Detergent-Based Decellularization for Anisotropic Cardiac-Specific Extracellular Matrix Scaffold Generation (open access)

Detergent-Based Decellularization for Anisotropic Cardiac-Specific Extracellular Matrix Scaffold Generation

Article describes how cell-derived extracellular matrix has become increasingly popular in tissue engineering applications due to its ability to provide tailored signals for desirable cellular responses. The objective of this study was to assess the efficacy of two detergent-based decellularization methods: a combination of ethylenediaminetetraacetic acid and sodium dodecyl sulfate and a combination of sodium deoxycholate and deoxyribonuclease.
Date: November 17, 2023
Creator: Chen, Te-An; Sharma, Dhavan; Jia, Wenkai; Ha, Donggi; Man, Kun; Zhang, Jianhua et al.
Object Type: Article
System: The UNT Digital Library
New approach based on enzyme stimulating of peptides for targeting drug resistance breast cancers (open access)

New approach based on enzyme stimulating of peptides for targeting drug resistance breast cancers

Data management plan for the grant, "New approach based on enzyme stimulating of peptides for targeting drug resistance breast cancers." In this project, we propose the development of selective self-assembling peptides that form nanofibers via a self-assembling process upon the action of Eyes absent (EYA) enzyme, specific to drug resistance Triple Negative Breast cancer cells (TNBC). The objectives are: Aim 1: Design and synthesize self-assembling peptide substrates for EYA enzymes; Aim 2:Determining the efficacy of peptide substrates for inhibiting TNBC in spheroid 3D cell cultures. The correlation between the enzyme kinetic and the activity of nanostructures for targeting EYA will be evaluated. Aim 3: The apoptosis response of the TNBC cells will be determined. This study will lead to finding the potent peptide substrate and the effective dose for inhibiting TNBC cells with apoptosis cell death.
Date: 2023-08-17/2024-07-31
Creator: Habibi, Neda
Object Type: Text
System: The UNT Digital Library
High-Throughput Investigation of Multiscale Deformation Mechanism in Additively Manufactured Ni Superalloy (open access)

High-Throughput Investigation of Multiscale Deformation Mechanism in Additively Manufactured Ni Superalloy

Article discusses how, in this paper, Inconel 718 (IN718) superalloy was processed by laser powder-bed fusion additive manufacturing (L-PBFAM), followed by heat treatment. Evidence of extensive deformation of twin networks and dislocation cells was revealed by transmission electron microscopy of the deformed region under the nanoindentation tip.
Date: February 17, 2023
Creator: Dhal, Abhijeet; Agrawal, Priyanka; Haridas, Ravi Sankar; Gaddam, Supreeth; Sharma, Aishani; Parganitha, Digvijay et al.
Object Type: Article
System: The UNT Digital Library
A Low-Power Wireless System for Predicting Early Signs of Sudden Cardiac Arrest Incorporating an Optimized CNN Model Implemented on NVIDIA Jetson (open access)

A Low-Power Wireless System for Predicting Early Signs of Sudden Cardiac Arrest Incorporating an Optimized CNN Model Implemented on NVIDIA Jetson

Article discusses the low survival rate of sudden cardiac arrest and its long-term risks that patients may experience. Authors propose a more effective method of recording and reporting sudden cardiac arrest symptoms so preventative measures may be instated earlier on to increase survival rate.
Date: February 17, 2023
Creator: Kota, Venkata Deepa; Sharma, Himanshu; Albert, Mark; Mahbub, Ifana; Mehta, Gayatri & Namuduri, Kamesh
Object Type: Article
System: The UNT Digital Library