Methods and results from the genome-wide association group at GAW20 (open access)

Methods and results from the genome-wide association group at GAW20

This article reports on promising statistical approaches and findings of the members of the Genome-wide Association Study group applied on real and simulated data which encompass the current topics of epigenetic and pharmacogenomics.
Date: September 17, 2018
Creator: Wang, Xuexia; Boekstegers, Felix & Brinster, Regina
Object Type: Article
System: The UNT Digital Library
Methods to evaluate rare variants gene-age interaction for triglycerides (open access)

Methods to evaluate rare variants gene-age interaction for triglycerides

This article discusses the development of two statistical methods to test the gene environment interaction effect of rare variants.
Date: September 17, 2018
Creator: Huayang Gao, Tony; Zhang, Jianjun; Medina Miguelangel, Diaz & Wang, Xuexia
Object Type: Article
System: The UNT Digital Library
Interactions between mitoNEET and NAF-1 in cells (open access)

Interactions between mitoNEET and NAF-1 in cells

This article uses yeast two-hybrid to demonstrate through vivo bimolecular fluorescence complementation (BiFC), direct coupling analysis (DCA), RNA-sequencing, ROS and iron imaging, and single and double shRNA lines with suppressed mNT, NAF-1 and mNT/NAF-1 expression, that mNT and NAF-1 directly interact in mammalian cells and could function in the same cellular pathway.
Date: April 20, 2017
Creator: Karmi, Ola; Holt, Sarah H.; Song, Luhua; Tamir, Sagi; Luo, Yuting; Bai, Fang et al.
Object Type: Article
System: The UNT Digital Library
Extremality and dynamically defined measures, part 1: Diophantine properties of quasi-decaying measures (open access)

Extremality and dynamically defined measures, part 1: Diophantine properties of quasi-decaying measures

This article presents a new method of proving the Diophantine extremality of various dynamically defined measures, vastly expanding the class of measures known to be extremal.
Date: April 7, 2017
Creator: Das, Tushar; Fishman, Lior; Simmons, David & Urbański, Mariusz
Object Type: Article
System: The UNT Digital Library
Phylogenetic analysis of eukaryotic NEET proteins uncovers a link between a key gene duplication event and the evolution of vertebrates (open access)

Phylogenetic analysis of eukaryotic NEET proteins uncovers a link between a key gene duplication event and the evolution of vertebrates

This article describes the use of three members of the human NEET protein family (CISD1, mitoNEET; CISD2, NAF-1 or Miner 1; and CISD3, Miner2) as guides to conduct a phylogenetic analysis of eukaryotic NEET proteins and their evolution.
Date: February 16, 2017
Creator: Inupakutika, Madhuri A.; Sengupta, Soham; Nechushtai, Rachel; Jennings, Patricia A.; Onuchic, José N.; Azad, Rajeev K. et al.
Object Type: Article
System: The UNT Digital Library
Polynomial Harmonic Decompositions (open access)

Polynomial Harmonic Decompositions

Article on polynomial harmonic decompositions. For real polynomials in two indeterminates a classical polynomial harmonic decomposition is extended from square-norm divisors to conic ones.
Date: January 2017
Creator: Anghel, Nicolae
Object Type: Article
System: The UNT Digital Library
Identification and Network-Enabled Characterization of Auxin Response Factor Genes in Medicago truncatula (open access)

Identification and Network-Enabled Characterization of Auxin Response Factor Genes in Medicago truncatula

This article discusses a comprehensive analysis of the Medicago truncatula genome and transcriptome that entailed search for novel Auxin Response Factor genes and the co-expression networks.
Date: December 9, 2016
Creator: Burks, David J. & Azad, Rajeev K.
Object Type: Article
System: The UNT Digital Library
Generalized parameter-free duality models in discrete minmax fractional programming based on second-order optimality conditions (open access)

Generalized parameter-free duality models in discrete minmax fractional programming based on second-order optimality conditions

This article discusses the construction of six generalized second-order parameter-free duality models, and proves several weak, strong, and strict converse duality theorems for a discrete minmax fractional programming problem using two partitioning schemes and various types of generalized second-order (ℱ, β, ɸ, 𝜌, θ, 𝑚)-univexity assumptions.
Date: November 8, 2016
Creator: Zalmai, G. J. & Verma, Ram U.
Object Type: Article
System: The UNT Digital Library
A novel statistical method for rare-variant association studies in general pedigrees (open access)

A novel statistical method for rare-variant association studies in general pedigrees

In this paper, the authors discuss a novel statistical method for rare-variant association studies in general pedigrees for quantitative traits. This method uses a retrospective view that treats the traits as fixed and the genotypes as random, which accounts for complex and undefined ascertainment of families.
Date: October 18, 2016
Creator: Zhu, Huanhuan; Wang, Zhenchuan; Wang, Xuexia & Sha, Qiuying
Object Type: Paper
System: The UNT Digital Library
Testing rare variants for hypertension using family-based tests with different weighting schemes (open access)

Testing rare variants for hypertension using family-based tests with different weighting schemes

This paper proposes 4 weighting schemes for the family-based rare variants test (FBAT-v) to test for the effects of both rare and common variants across the genome.
Date: October 18, 2016
Creator: Wang, Xuexia; Zhao, Xingwang & Zhou, Jin
Object Type: Paper
System: The UNT Digital Library
Unconventional height functions in simultaneous Diophantine approximation (open access)

Unconventional height functions in simultaneous Diophantine approximation

This article discusses three examples of nonstandard height functions, computing their exponents of irrationality as well as giving more precise results.
Date: October 3, 2016
Creator: Fishman, Lior & Simmons, David
Object Type: Article
System: The UNT Digital Library
Role of Exponential Type Random Invexities for Asymptotically Sufficient Efficiency Conditions in Semi-Infinite Multi-Objective Fractional Programming (open access)

Role of Exponential Type Random Invexities for Asymptotically Sufficient Efficiency Conditions in Semi-Infinite Multi-Objective Fractional Programming

This article introduces several notions of random exponential type asymptotic invexities to establish results to the context of a class of asymptotically sufficient efficiency conditions in semi-infinite multi-objective fractional programing.
Date: September 2, 2016
Creator: Verma, Ram U. & Seol, Youngsoo
Object Type: Article
System: The UNT Digital Library
Existence and Nonexistence of Solutions for Semilinear Equations on Exterior Domains (open access)

Existence and Nonexistence of Solutions for Semilinear Equations on Exterior Domains

This article studies radial solutions of Δu + K(r)ƒ(u) = 0 on the exterior of the ball of radius R > 0 centered at the origin in ℝᴺ where ƒ is odd with ƒ < 0 on (0,ß), ƒ > 0 on (β, δ), ƒ ≡ 0 for u > δ, and where the function K(r) is assumed to be positive and K(r) → 0 as r → ∞.
Date: August 22, 2016
Creator: Iaia, Joseph A.
Object Type: Article
System: The UNT Digital Library
Almost Holomorphic Poincaré Series Corresponding to Products of Harmonic Siegel–Maass Forms (open access)

Almost Holomorphic Poincaré Series Corresponding to Products of Harmonic Siegel–Maass Forms

This article investigates Poincaré series, particularly the study of Siegel–Poincaré series of degree 2 attached to products of terms of Fourier series of harmonic Siegel–Maass forms and holomorphic Siegel modular forms
Date: April 15, 2016
Creator: Bringmann, Kathrin; Richter, Olav K. & Westerholt-Raum, Martin
Object Type: Article
System: The UNT Digital Library
Glucose or Altered Ceramide Biosynthesis Mediate Oxygen Deprivation Sensitivity Through Novel Pathways Revealed by Transcriptome Analysis in Caenorhabditis elegans (open access)

Glucose or Altered Ceramide Biosynthesis Mediate Oxygen Deprivation Sensitivity Through Novel Pathways Revealed by Transcriptome Analysis in Caenorhabditis elegans

This article discusses how RNA-sequencing analysis was performed to assess how a glucose-supplemented diet and/or a hyl-2 mutation altered the transcriptome.
Date: August 5, 2016
Creator: Ladage, Mary L.; King, Skylar D.; Burks, David J.; Quan, Daniel L.; Garcia, Anastacia M.; Azad, Rajeev K. et al.
Object Type: Article
System: The UNT Digital Library
Identification of Novel Genomic Islands in Liverpool Epidemic Strain of Pseudomonas aeruginosa Using Segmentation and Clustering (open access)

Identification of Novel Genomic Islands in Liverpool Epidemic Strain of Pseudomonas aeruginosa Using Segmentation and Clustering

This article utilizes a recursive segmentation and cluster procedure presented as a genome-mining tool, GEMINI, to decipher genomic islands and understand their contributions to the evolution of virulence and antibiotic resistance in Pseudomonas aeruginosa.
Date: August 3, 2016
Creator: Jani, Mehul; Mathee, Kalal & Azad, Rajeev K.
Object Type: Article
System: The UNT Digital Library
Existence of Solutions for Semilinear Problems With Prescribed Number of Zeros on Exterior Domains (open access)

Existence of Solutions for Semilinear Problems With Prescribed Number of Zeros on Exterior Domains

This article proves the existence of an infinite number of radial solutions of Δ(u) + f(u) = 0 with prescribed number of zeros on the exterior of the ball of radius R > 0 centered at the origin in ℝᴺ where f is odd with f < 0 on (0, β), f > 0 on (β,∞) where β > 0.
Date: May 3, 2016
Creator: Joshi, Janak & Iaia, Joseph A.
Object Type: Article
System: The UNT Digital Library
Generalized second-order parametric optimality conditions in semiinfinitediscrete minmax fractional programming and second order (F,β,φ,ρ,θ,m)-univexity (open access)

Generalized second-order parametric optimality conditions in semiinfinitediscrete minmax fractional programming and second order (F,β,φ,ρ,θ,m)-univexity

Article discusses establishing numerous sets of generalized second order paramertic sufficient optimality conditions for a semiinfinite discrete minmax fractional programming problem, while the results on semiinfinite discrete minmax fractional programming problem achieved based on some partitioning schemes under various types of generalized second order univexity assumptions.
Date: February 28, 2016
Creator: Verma, Ram U. & Zalmai, G. J.
Object Type: Article
System: The UNT Digital Library
Rapid identification of causative insertions underlying Medicago truncatula Tnt1 mutants defective in symbiotic nitrogen fixation from a forward genetic screen by whole genome sequencing (open access)

Rapid identification of causative insertions underlying Medicago truncatula Tnt1 mutants defective in symbiotic nitrogen fixation from a forward genetic screen by whole genome sequencing

This article demonstrates that whole genome sequencing is an efficient approach for identification of causative genes underlying symbiotic nitrogen fixation defective phenotypes in Medicago truncatula Tnt1 insertion mutants obtained via forward genetic screens.
Date: February 27, 2016
Creator: Veerappan, Vijaykumar; Jani, Mehul; Kadel, Khem; Troiani, Taylor; Gale, Ronny; Mayes, Tyler et al.
Object Type: Article
System: The UNT Digital Library
ABA Is Required for Plant Acclimation to a Combination of Salt and Heat Stress (open access)

ABA Is Required for Plant Acclimation to a Combination of Salt and Heat Stress

This article highlights the important role abscisic acid plays in the acclimation of plants to a combination of two different abiotic stresses.
Date: January 29, 2016
Creator: Suzuki, Nobuhiro; Bassil, Elias; Hamilton, Jason S.; Inupakutika, Madhuri A.; Zandalinas, Sara I.; Tripathy, Deesha et al.
Object Type: Article
System: The UNT Digital Library
Curvature Bundle Morphisms for Hypersurface Generalized Dirac Operators (open access)

Curvature Bundle Morphisms for Hypersurface Generalized Dirac Operators

This article establishes uses a Gauss-like relationship to examine how the curvature bundle morphisms relate.
Date: 2016
Creator: Anghel, Nicolae
Object Type: Article
System: The UNT Digital Library
Epilepsy Detection Using EEG with Different Time Frames (open access)

Epilepsy Detection Using EEG with Different Time Frames

This article analyzes and classifies EEG signals using wavelets decomposition and support vector machines (SVM).
Date: 2016
Creator: Liu, Jianguo
Object Type: Article
System: The UNT Digital Library
Loitering at the hilltop on exterior domains (open access)

Loitering at the hilltop on exterior domains

In this article, the author proves the existence of an infinite number of radial solutions of Δu+f(u)=0 on the exterior of the ball of radius R>0 centered at the origin and f is odd with f<0 on (0,β), f>0 on (β,δ), and f≡0 for u>δ. The primitive F(u)=∫u0f(t)dt has a "hilltop" at u=δ which allows one to use the shooting method and ODE techniques to prove the existence of solutions.
Date: November 23, 2015
Creator: Iaia, Joseph A.
Object Type: Article
System: The UNT Digital Library
Activation of apoptosis in NAF-1-deficient human epithelial breast cancer cells (open access)

Activation of apoptosis in NAF-1-deficient human epithelial breast cancer cells

This article shows that small hairpin RNA-mediated suppresion of NAF-1 results in the activation of apoptosis in epithelial breast cancer cells and xenograft tumors.
Date: November 11, 2015
Creator: Holt, Sarah H.; Darash-Yahana, Merav; Sohn, Yang Sung; Song, Luhua; Karmi, Ola; Tamir, Sagi et al.
Object Type: Article
System: The UNT Digital Library