The contact patterns among individuals can significantly affect the progress of an infectious outbreak within a population. Gathering data about these interaction and mixing patterns is essential to assess computational modeling of infectious diseases. Various self-report approaches have been designed in different studies to collect data about contact rates and patterns. Recent advances in sensing technology provide researchers with a bilateral automated data collection devices to facilitate contact gathering overcoming the disadvantages of previous approaches. In this study, a novel unilateral wearable sensing architecture has been proposed that overcome the limitations of the bi-lateral sensing. Our unilateral wearable sensing system gather contact data using hybrid sensor arrays embedded in wearable shirt. A smartphone application has been used to transfer the collected sensors data to the cloud and apply deep learning model to estimate the number of human contacts and the results are stored in the cloud database. The deep learning model has been developed on the hand labelled data over multiple experiments. This model has been tested and evaluated, and these results were reported in the study. Sensitivity analysis has been performed to choose the most suitable image resolution and format for the model to estimate contacts and to analyze …

Word embeddings is a useful method that has shown enormous success in various NLP tasks, not only in open domain but also in biomedical domain. The biomedical domain provides various domain specific resources and tools that can be exploited to improve performance of these word embeddings. However, most of the research related to word embeddings in biomedical domain focuses on analysis of model architecture, hyper-parameters and input text. In this paper, we use SemMedDB to design new sentences called `Semantic Sentences'. Then we use these sentences in addition to biomedical text as inputs to the word embedding model. This approach aims at introducing biomedical semantic types defined by UMLS, into the vector space of word embeddings. The semantically rich word embeddings presented here rivals state of the art biomedical word embedding in both semantic similarity and relatedness metrics up to 11%. We also demonstrate how these semantic types in word embeddings can be utilized.

Ulcerative colitis (UC) is a chronic inflammatory disease characterized by periods of relapses and remissions affecting more than 500,000 people in the United States. To achieve the therapeutic goals of UC, which are to first induce and then maintain disease remission, doctors need to evaluate the severity of UC of a patient. However, it is very difficult to evaluate the severity of UC objectively because of non-uniform nature of symptoms and large variations in their patterns. To address this, in our previous works, we developed two different approaches in which one is using the image textures, and the other is using CNN (convolutional neural network) to measure and classify objectively the severity of UC presented in optical colonoscopy video frames. But, we found that the image texture based approach could not handle larger number of variations in their patterns, and the CNN based approach could not achieve very high accuracy. In this paper, we improve our CNN based approach in two ways to provide better accuracy for the classification. We add more thorough and essential preprocessing, and generate more classes to accommodate large variations in their patterns. The experimental results show that the proposed preprocessing can improve the overall accuracy …

Vehicular ad-hoc networks (VANETs) are used for vehicle-to-vehicle (V2V) and vehicle-to-infrastructure (V2I) communications. The IEEE 802.11p/WAVE (Wireless Access in Vehicular Environment) and with WAVE Short Messaging Protocol (WSMP) has been proposed as the standard protocol for designing applications for VANETs. This communication protocol must be thoroughly tested before reliable and efficient applications can be built using its protocols. In this paper, we perform on-road experiments in a variety of scenarios to evaluate the performance of the standard. We use commercial VANET devices with 802.11p/WAVE compliant chipsets for both BSM (basic safety messages) as well as video streaming applications using WSMP as a communication protocol. We show that while the standard performs well for BSM application in lightly loaded conditions, the performance becomes inferior when traffic and other performance metric increases. Furthermore, we also show that the standard is not suitable for video streaming due to the bursty nature of traffic and the bandwidth throttling, which is a major shortcoming for V2X applications.

With an ever-growing number of publications in the biomedical domain, it becomes likely that important implicit connections between individual concepts of biomedical knowledge are overlooked. Literature based discovery (LBD) is in practice for many years to identify plausible associations between previously unrelated concepts. In this paper, we present a new, completely automatic and interactive system that creates a graph-based knowledge base to capture multifaceted complex associations among biomedical concepts. For a given pair of input concepts, our system auto-generates a list of ranked subgraphs uncovering possible previously unnoticed associations based on context information. To rank these subgraphs, we implement a novel ranking method using the context information obtained by performing random walks on the graph. In addition, we enhance the system by training a Neural Network Classifier to output the likelihood of the two concepts being likely related, which provides better insights to the end user.

Consumer's opinions and sentiments on products can reflect the performance of products in general or in various aspects. Analyzing these data is becoming feasible, considering the availability of immense data and the power of natural language processing. However, retailers have not taken full advantage of online comments. This work is dedicated to a solution for automatically analyzing and summarizing these valuable data at both product and category levels. In this research, a system was developed to retrieve and analyze extensive data from public online resources. A parallel framework was created to make this system extensible and efficient. In this framework, a star topological network was adopted in which each computing unit was assigned to retrieve a fraction of data and to assess sentiment. Finally, the preprocessed data were collected and summarized by the central machine which generates the final result that can be rendered through a web interface. The system was designed to have sound performance, robustness, manageability, extensibility, and accuracy.

Twitter has quickly become one of the most popular social media sites. It has 313 million monthly active users, and 500 million tweets are published daily. With the massive number of tweets, Twitter users share information about a location along with the temporal awareness. In this work, I focus on tweets where author of the tweets exclusively mentions a location in the tweet. Natural language processing systems can leverage wide range of information from the tweets to build applications like recommender systems that predict the location of the author. This kind of system can be used to increase the visibility of the targeted audience and can also provide recommendations interesting places to visit, hotels to stay, restaurants to eat, targeted on-line advertising, and co-traveler matching based on the temporal information extracted from a tweet. In this work I determine if the author of the tweet is present in the mentioned location of the tweet. I also determine if the author is present in the location before tweeting, while tweeting, or after tweeting. I introduce 5 temporal tags (before the tweet but > 24 hours; before the tweet but < 24 hours; during the tweet is posted; after the tweet is …

Component failures can result in catastrophic behaviors in safety critical embedded systems, sometimes resulting in loss of life. Component failures can be treated as off nominal behaviors (ONBs) with respect to the components and sub systems involved in an embedded system. A lot of research is being carried out to tackle the problem of ONBs. These approaches are mainly focused on the states (i.e., desired and undesired states of a system at a given point of time to detect ONBs). In this paper, an approach is discussed to detect component failures and critical components of an embedded system. The approach is based on fault tree analysis (FTA), applied to the requirements specification of embedded systems at design time to find out the relationship between individual component failures and overall system failure. FTA helps in determining both qualitative and quantitative relationship between component failures and system failure. Analyzing the system at design time helps in detecting component failures and critical components and helps in devising strategies to mitigate component failures at design time and improve overall safety and reliability of a system.

In developing countries, acute respiratory infections (ARIs) are responsible for two million deaths per year. Most victims are children who are less than 5 years old. Pneumonia kills 5000 children per day. The statistics for cardiovascular diseases (CVDs) are even more alarming. According to a 2009 report from the World Health Organization (WHO), CVDs kill 17 million people per year. In many resource-poor parts of the world such as India and China, many people are unable to access cardiologists, pulmonologists, and other specialists. Hence, low skilled health professionals are responsible for screening people for ARIs and CVDs in these areas. For example, in the rural areas of the Philippines, there is only one doctor for every 10,000 people. By contrast, the United States has one doctor for every 500 Americans. Due to advances in technology, it is now possible to use a smartphone for audio recording, signal processing, and machine learning. In my thesis, I have developed an Android application named Smart Auscultation. Auscultation is a process in which physicians listen to heart and lung sounds to diagnose disorders. Cardiologists spend years mastering this skill. The Smart Auscultation application is capable of recording and classifying heart sounds, and can be …

This thesis describes an approach for object recognition using the chordiogram shape-based descriptor. Global shape representations are highly susceptible to clutter generated due to the background or other irrelevant objects in real-world images. To overcome the problem, we aim to extract precise object shape using superpixel segmentation, perceptual grouping, and connected components. The employed shape descriptor chordiogram is based on geometric relationships of chords generated from the pairs of boundary points of an object. The chordiogram descriptor applies holistic properties of the shape and also proven suitable for object detection and digit recognition mechanisms. Additionally, it is translation invariant and robust to shape deformations. In spite of such excellent properties, chordiogram is not scale-invariant. To this end, we propose scale invariant chordiogram descriptors and intend to achieve a similar performance before and after applying scale invariance. Our experiments show that we achieve similar performance with and without scale invariance for silhouettes and real world object images. We also show experiments at different scales to confirm that we obtain scale invariance for chordiogram.

In recent years, social media platforms such as Twitter and Facebook have emerged as effective tools for broadcasting messages worldwide during disaster events. With millions of messages posted through these services during such events, it has become imperative to identify valuable information that can help the emergency responders to develop effective relief efforts and aid victims. Many studies implied that the role of social media during disasters is invaluable and can be incorporated into emergency decision-making process. However, due to the "big data" nature of social media, it is very labor-intensive to employ human resources to sift through social media posts and categorize/classify them as useful information. Hence, there is a growing need for machine intelligence to automate the process of extracting useful information from the social media data during disaster events. This dissertation addresses the following questions: In a social media stream of messages, what is the useful information to be extracted that can help emergency response organizations to become more situationally aware during and following a disaster? What are the features (or patterns) that can contribute to automatically identifying messages that are useful during disasters? We explored a wide variety of features in conjunction with supervised learning algorithms …

In recent years, brain computer interfaces (BCIs) have gained popularity in non-medical domains such as the gaming, entertainment, personal health, and marketing industries. A growing number of companies offer various inexpensive consumer grade BCIs and some of these companies have recently introduced the concept of BCI "App stores" in order to facilitate the expansion of BCI applications and provide software development kits (SDKs) for other developers to create new applications for their devices. The BCI applications access to users' unique brainwave signals, which consequently allows them to make inferences about users' thoughts and mental processes. Since there are no specific standards that govern the development of BCI applications, its users are at the risk of privacy breaches. In this work, we perform first comprehensive analysis of BCI App stores including software development kits (SDKs), application programming interfaces (APIs), and BCI applications w.r.t privacy issues. The goal is to understand the way brainwave signals are handled by BCI applications and what threats to the privacy of users exist. Our findings show that most applications have unrestricted access to users' brainwave signals and can easily extract private information about their users without them even noticing. We discuss potential privacy threats posed by …

Mobile applications are growing in popularity and pose new problems in the area of software testing. In particular, mobile applications heavily depend upon user interactions and a dynamically changing environment of system events. In this thesis, we focus on user-driven events and use Q-learning, a reinforcement machine learning algorithm, to generate tests for Android applications under test (AUT). We implement a framework that automates the generation of GUI test cases by using our Q-learning approach and compare it to a uniform random (UR) implementation. A novel feature of our approach is that we generate user-driven event sequences through the GUI, without the source code or the model of the AUT. Hence, considerable amount of cost and time are saved by avoiding the need for model generation for generating the tests. Our results show that the systematic path exploration used by Q-learning results in higher average code coverage in comparison to the uniform random approach.

This work presents an investigation of a piezoelectric sensor based energy harvesting system, which collects energy from the surrounding environment. Increasing costs and scarcity of fossil fuels is a great concern today for supplying power to electronic devices. Furthermore, generating electricity by ordinary methods is a complicated process. Disposal of chemical batteries and cables is polluting the nature every day. Due to these reasons, research on energy harvesting from renewable resources has become mandatory in order to achieve improved methods and strategies of generating and storing electricity. Many low power devices being used in everyday life can be powered by harvesting energy from natural energy resources. Power overhead and power energy efficiency is of prime concern in electronic circuits. In this work, an energy harvester is modeled and simulated in Simscape™ for the functional analysis and comparison of achieved outcomes with previous work. Results demonstrate that the harvester produces power in the 0 μW to 100 μW range, which is an adequate amount to provide supply to low power devices. Power efficiency calculations also demonstrate that the implemented harvester is capable of generating and storing power for low power pervasive applications.

This work describes an approach to determine whether people participate in the events they tweet about. Specifically, we determine whether people are participants in events with respect to the tweet timestamp. We target all events expressed by verbs in tweets, including past, present and events that may occur in future. We define event participant as people directly involved in an event regardless of whether they are the agent, recipient or play another role. We present an annotation effort, guidelines and quality analysis with 1,096 event mentions. We discuss the label distributions and event behavior in the annotated corpus. We also explain several features used and a standard supervised machine learning approach to automatically determine if and when the author is a participant of the event in the tweet. We discuss trends in the results obtained and devise important conclusions.

Epidemiologists rely on human interaction networks for determining states and dynamics of disease propagations in populations. However, such networks are empirical snapshots of the past. It will greatly benefit if human interaction networks are statistically predicted and dynamically created while an epidemic is in progress. We develop an application framework for the generation of human interaction networks and running epidemiological processes utilizing research on human mobility patterns and agent-based modeling. The interaction networks are dynamically constructed by incorporating different types of Random Walks and human rules of engagements. We explore the characteristics of the created network and compare them with the known theoretical and empirical graphs. The dependencies of epidemic dynamics and their outcomes on patterns and parameters of human motion and motives are encountered and presented through this research. This work specifically describes how the types and parameters of random walks define properties of generated graphs. We show that some configurations of the system of agents in random walk can produce network topologies with properties similar to small-world networks. Our goal is to find sets of mobility patterns that lead to empirical-like networks. The possibility of phase transitions in the graphs due to changes in the parameterization of agent …

The use of electroencephalogram (EEG), an electrophysiological monitoring method for recording the brain activity, for authentication has attracted the interest of researchers for over a decade. In addition to exhibiting qualities of biometric-based authentication, they are revocable, impossible to mimic, and resistant to coercion attacks. However, EEG signals carry a wealth of information about an individual and can reveal private information about the user. This brings significant privacy issues to EEG-based authentication systems as they have access to raw EEG signals. This thesis proposes a privacy-preserving EEG-based authentication system that preserves the privacy of the user by not revealing the raw EEG signals while allowing the system to authenticate the user accurately. In that, perceptual hashing is utilized and instead of raw EEG signals, their perceptually hashed values are used in the authentication process. In addition to describing the authentication process, algorithms to compute the perceptual hash are developed based on two feature extraction techniques. Experimental results show that an authentication system using perceptual hashing can achieve performance comparable to a system that has access to raw EEG signals if enough EEG channels are used in the process. This thesis also presents a security analysis to show that perceptual hashing …

The history of mitigation programs to contain vector-borne diseases is a story of successes and failures. Due to the complex interplay among multiple factors that determine disease dynamics, the general principles for timely and specific intervention for incidence reduction or eradication of life-threatening diseases has yet to be determined. This research discusses computational methods developed to assist in the understanding of complex relationships affecting vector-borne disease dynamics. A computational framework to assist public health practitioners with exploring the dynamics of vector-borne diseases, such as malaria and dengue in homogenous and heterogeneous populations, has been conceived, designed, and implemented. The framework integrates a stochastic computational model of interactions to simulate horizontal disease transmission. The intent of the computational modeling has been the integration of stochasticity during simulation of the disease progression while reducing the number of necessary interactions to simulate a disease outbreak. While there are improvements in the computational time reducing the number of interactions needed for simulating disease dynamics, the realization of interactions can remain computationally expensive. Using multi-threading technology to improve performance upon the original computational model, multi-threading experimental results have been tested and reported. In addition, to the contact model, the modeling of biological processes specific to …

Network security is a complex field that is handled by security professionals who need certain expertise and experience to configure security systems. With the ever increasing size of the networks, managing them is going to be a daunting task. What kind of solution can be used to generate effective security configurations by both security professionals and nonprofessionals alike? In this thesis, a web tool is developed to simplify the process of configuring security systems by translating direct human language input into meaningful, working security rules. These human language inputs yield the security rules that the individual wants to implement in their network. The human language input can be as simple as, "Block Facebook to my son's PC". This tool will translate these inputs into specific security rules and install the translated rules into security equipment such as virtualized Cisco FWSM network firewall, Netfilter host-based firewall, and Snort Network Intrusion Detection. This tool is implemented and tested in both a traditional network and a cloud environment. One thousand input policies were collected from various users such as staff from UNT departments' and health science, including individuals with network security background as well as students with a non-computer science background to analyze …

Managing large-scale dynamical systems (e.g., transportation systems, complex information systems, and power networks, etc.) in real-time is very challenging considering their complicated system dynamics, intricate network interactions, large scale, and especially the existence of various uncertainties. To address this issue, intelligent techniques which can quickly design decision-making strategies that are robust to uncertainties are needed. This dissertation aims to conquer these challenges by exploring a data-driven decision-making framework, which leverages big-data techniques and scalable uncertainty evaluation approaches to quickly solve optimal control problems. In particular, following techniques have been developed along this direction: 1) system modeling approaches to simplify the system analysis and design procedures for multiple applications; 2) effective simulation and analytical based approaches to efficiently evaluate system performance and design control strategies under uncertainty; and 3) big-data techniques that allow some computations of control strategies to be completed offline. These techniques and tools for analysis, design and control contribute to a wide range of applications including air traffic flow management, complex information systems, and airborne networks.

Students often use the web as a source of help for problems that they encounter on programming assignments.In this work, we seek to understand how students use the web to search for help on their assignments.We used a mixed methods approach with 344 students who complete a survey and 41 students who participate in a focus group meetings and helped in recording data about their search habits.The survey reveals data about student reported search habits while the focus group uses a web browser plug-in to record actual search patterns.We examine the results collectively and as broken down by class year.Survey results show that at least 2/3 of the students from each class year rely on search engines to locate resources for help with their programming bugs in at least half of their assignments;search habits vary by class year;and the value of different types of resources such as tutorials and forums varies by class year.Focus group results exposes the high frequency web sites used by the students in solving their programming assignments.

Did you stand at a door with a bunch of keys and tried to find the right one to unlock the door? Did you hold a flower and wonder the name of it? A need of object recognition could rise anytime and any where in our daily lives. With the development of mobile devices object recognition applications become possible to provide immediate assistance. However, performing complex tasks in even the most advanced mobile platforms still faces great challenges due to the limited computing resources and computing power. In this thesis, we present an object recognition system that resides and executes within a mobile device, which can efficiently extract image features and perform learning and classification. To account for the computing constraint, a novel feature extraction method that minimizes the data size and maintains data consistency is proposed. This system leverages principal component analysis method and is able to update the trained classifier when new examples become available . Our system relieves users from creating a lot of examples and makes it user friendly. The experimental results demonstrate that a learning method trained with a very small number of examples can achieve recognition accuracy above 90% in various acquisition conditions. In …

There are several types of disorders that affect our colon’s ability to function properly such as colorectal cancer, ulcerative colitis, diverticulitis, irritable bowel syndrome and colonic polyps. Automatic detection of these diseases would inform the endoscopist of possible sub-optimal inspection during the colonoscopy procedure as well as save time during post-procedure evaluation. But existing systems only detects few of those disorders like colonic polyps. In this dissertation, we address the automatic detection of another important disorder called ulcerative colitis. We propose a novel texture feature extraction technique to detect the severity of ulcerative colitis in block, image, and video levels. We also enhance the current informative frame filtering methods by detecting water and bubble frames using our proposed technique. Our feature extraction algorithm based on accumulation of pixel value difference provides better accuracy at faster speed than the existing methods making it highly suitable for real-time systems. We also propose a hybrid approach in which our feature method is combined with existing feature method(s) to provide even better accuracy. We extend the block and image level detection method to video level severity score calculation and shot segmentation. Also, the proposed novel feature extraction method can detect water and bubble frames …

POD (Point of Dispensing)-based emergency response plans involving mass prophylaxis may seem feasible when considering the choice of dispensing points within a region, overall population density, and estimated traffic demands. However, the plan may fail to serve particular vulnerable sub-populations, resulting in access disparities during emergency response. Federal authorities emphasize on the need to identify sub-populations that cannot avail regular services during an emergency due to their special needs to ensure effective response. Vulnerable individuals require the targeted allocation of appropriate resources to serve their special needs. Devising schemes to address the needs of vulnerable sub-populations is essential for the effectiveness of response plans. This research focuses on data-driven computational methods to quantify and address vulnerabilities in response plans that require the allocation of targeted resources. Data-driven methods to identify and quantify vulnerabilities in response plans are developed as part of this research. Addressing vulnerabilities requires the targeted allocation of appropriate resources to PODs. The problem of resource allocation to PODs during public health emergencies is introduced and the variants of the resource allocation problem such as the spatial allocation, spatio-temporal allocation and optimal resource subset variants are formulated. Generating optimal resource allocation and scheduling solutions can be computationally hard …