The purpose of this study was to examine the effect of post-resistance exercise alcohol ingestion on LPS-stimulated production of IFNγ, TNF-α, IL-1β, IL-6, IL-8, and IL-10. Recreationally resistance-trained men (n = 10, 25 ± 3 yr, 177 ± 7 cm, 83.8 ± 15.7 kg, 14.8 ± 8.5% body fat) and women (n = 8, 23 ± 2 yr, 161 ± 3 cm, 59.5 ± 6.0 kg, 26.5 ± 3.0% body fat) completed the study. Participants visited the laboratory for an initial visit at which time they were screened, familiarized with procedures, and had their 1-repetition maximum (1RM) back squat tested. Subsequently, participants visited the laboratory 2 more times and completed 2 identical heavy resistance exercise bouts (6 sets of 10 repetitions of 80% 1RM back squat) after which a beverage, either containing alcohol (alcohol condition, ALC; 1.09 g EtOH per kg fat free mass) or water (placebo condition, PLA), was administered. Blood samples were collected before exercise (PRE), and at 3 hours (3h) and 5 hours (5h) after exercise. Samples were stimulated with lipopolysaccharide (LPS) and cultured overnight. Supernatant was collected and analyzed for IFNγ, TNF-α, IL-1β, IL-6, IL-8, and IL-10. A significant (p < 0.05) main effect for time …

The purpose of this investigation was to examine the acute hormonal response to a bout of kettlebell swing exercise. Ten healthy men (19-30 y, 23.6 ± 3.5 y, 174.6 ± 5.7 cm, 78.7 ± 9.9 kg) who were engaged in resistance training at least twice per week but were inexperienced with kettlebell swings participated in this study. Participants were familiarized with the kettlebell swing exercise during an initial visit. During the subsequent experimental protocol visit, participants performed 12 rounds of 30 seconds of 16-kg kettlebell swings alternated with 30 seconds of rest. Heart rate (HR) and rating of perceived exertion (RPE) were measured at the end of every round of swings. Fasted blood samples were collected pre-exercise (PRE), immediately post (IP), 15 minutes post (P15), and 30 minutes post exercise (P30) and analyzed for total testosterone (T), growth hormone (GH), cortisol, and lactate concentrations. Participants completed a total of 227 ± 23 swings (average swings per round: 19 ± 2). HR and RPE increased significantly (P < 0.05) throughout the exercise protocol. Lactate concentrations were significantly increased at all post exercise time points compared to PRE. T was significantly increased at IP compared to PRE. GH was significantly increased at …