Traditional Public Health decision-support can benefit from the Web and social media revolution. This dissertation presents approaches to mining social media benefiting public health epidemiology. Through discovery and analysis of trends in Influenza related blogs, a correlation to Centers for Disease Control and Prevention (CDC) influenza-like-illness patient reporting at sentinel health-care providers is verified. A second approach considers personal beliefs of vaccination in social media. A vaccine for human papillomavirus (HPV) was approved by the Food and Drug Administration in May 2006. The virus is present in nearly all cervical cancers and implicated in many throat and oral cancers. Results from automatic sentiment classification of HPV vaccination beliefs are presented which will enable more accurate prediction of the vaccine's population-level impact. Two epidemic models are introduced that embody the intimate social networks related to HPV transmission. Ultimately, aggregating these methodologies with epidemic and social network modeling facilitate effective development of strategies for targeted interventions.

This dissertation describes WikiRank, an unsupervised method of assigning relative values to elements of a broad coverage encyclopedic information source in order to identify those entries that may be relevant to a given piece of text. The valuation given to an entry is based not on textual similarity but instead on the links that associate entries, and an estimation of the expected frequency of visitation that would be given to each entry based on those associations in context. This estimation of relative frequency of visitation is embodied in modifications to the random walk interpretation of the PageRank algorithm. WikiRank is an effective algorithm to support natural language processing applications. It is shown to exceed the performance of previous machine learning algorithms for the task of automatic topic identification, providing results comparable to that of human annotators. Second, WikiRank is found useful for the task of recognizing text-based paraphrases on a semantic level, by comparing the distribution of attention generated by two pieces of text using the encyclopedic resource as a common reference. Finally, WikiRank is shown to have the ability to use its base of encyclopedic knowledge to recognize terms from different ontologies as describing the same thing, and thus …

New circuit design techniques that accommodate lower supply voltages necessary for portable systems need to be integrated into the semiconductor intellectual property (IP) core. Systems that once worked at 3.3 V or 2.5 V now need to work at 1.8 V or lower, without causing any performance degradation. Also, the fluctuation of device characteristics caused by process variation in nanometer technologies is seen as design yield loss. The numerous parasitic effects induced by layouts, especially for high-performance and high-speed circuits, pose a problem for IC design. Lack of exact layout information during circuit sizing leads to long design iterations involving time-consuming runs of complex tools. There is a strong need for low-power, high-performance, parasitic-aware and process-variation-tolerant circuit design. This dissertation proposes methodologies and techniques to achieve variability, power, performance, and parasitic-aware circuit designs. Three approaches are proposed: the single iteration automatic approach, the hybrid Monte Carlo and design of experiments (DOE) approach, and the corner-based approach. Widely used mixed-signal circuits such as analog-to-digital converter (ADC), voltage controlled oscillator (VCO), voltage level converter and active pixel sensor (APS) have been designed at nanoscale complementary metal oxide semiconductor (CMOS) and subjected to the proposed methodologies. The effectiveness of the proposed methodologies has …

This dissertation is composed of research studies that contribute to three research areas including social context-aware computing, internal context-aware computing, and human behavioral data mining. In social context-aware computing, four studies are conducted. First, mobile phone user calling behavioral patterns are characterized in forms of randomness level where relationships among them are then identified. Next, a study is conducted to investigate the relationship between the calling behavior and organizational groups. Third, a method is presented to quantitatively define mobile social closeness and social groups, which are then used to identify social group sizes and scaling ratio. Last, based on the mobile social grouping framework, the significant role of social ties in communication patterns is revealed. In internal context-aware computing, two studies are conducted where the notions of internal context are intention and situation. For intentional context, the goal is to sense the intention of the user in placing calls. A model is thus presented for predicting future calls envisaged as a call predicted list (CPL), which makes use of call history to build a probabilistic model of calling behavior. As an incoming call predictor, CPL is a list of numbers/contacts that are the most likely to be the callers within …

The motivation of this work is to understand E-shape analysis and how it can be applied to various classification tasks. It has a powerful feature to not only look at what information is contained, but rather how that information looks. This new technique gives E-shape analysis the ability to be language independent and to some extent size independent. In this thesis, I present a new mechanism to characterize an email without using content or context called E-shape analysis for email. I explore the applications of the email shape by carrying out a case study; botnet detection and two possible applications: spam filtering and social-context based finger printing. The second part of this thesis takes what I apply E-shape analysis to activity recognition of humans. Using the Android platform and a T-Mobile G1 phone I collect data from the triaxial accelerometer and use it to classify the motion behavior of a subject.