This dissertation tracks the intimate relationship between writing and the body to add new dimensions to humoral criticism and textual studies of Renaissance literature. Most humor theory focuses on the volatile, permeable nature of the body, and its vulnerability to environmental stimuli, neglecting the important role that written texts play in this economy of fluids. I apply the principles of humor theory to the study of handwritten and printed texts. This approach demonstrates that the textual economy of the period—reading, writing, publishing, exchanging letters, performing all of the above on stage—mirrors the economy of fluids that governed the humoral body. Early modern readers and writers could imagine textual activities not only as cerebral, abstract concepts, but also as sexual activities, as processes of ingestion and regurgitation. My study of ink combines humoral, historical materialist, and ecocritical modes of study. Materialist critics have examined the quill, paper, and printing press as metaphors for the body; however, the ink within them remains unexamined. This dissertation infuses the figurative body of the press with circulating passions, and brings to bear the natural, biochemical properties that ink lends to the texts it creates. Considering the influence of written and printed materials on the body …