O-Acetylserine Sulfhydrylase (OASS) is a pyridoxal phosphate enzyme that catalyzes the reaction of O-acetyl-Lserine with sulfide to give L-cysteine. OASS is present as two isoforms, designated -A and -B. The kinetic mechanism of OASS-A is well known and there is also much known concerning the acid-base chemistry of the enzyme. However, little is known concerning the location of the rate determining steps, the sequencing of chemical steps that occur at the active site, or the nature of the rate determining transition states. The studies performed to help elucidate these aspects of the OASS-A mechanism included determination of the thermodynamics of both half reactions, along with studies utilizing substrate analogs of OAS halting the reaction at specific points along the reaction pathway allowing the identification of reaction intermediates. The free energy change of the first half reaction was shown to be -5.7 Kcal/mole while the second half reaction was shown to be, for all intents and purposes, irreversible. Intermediates along the reaction pathway that have been previously identified include the internal Schiff base and the a-aminoacrylate. The external Schiff base was identified using the analogs cysteine, alanine, and glycine while the geminal diamine was identified using the analog serine. Formation of …

This thesis reports on the use of active and passive voice in the workplace and classroom through analysis of surveys completed by 37 employees and 66 students. The surveys offered six categories of business writing with ten sets of two sentences each, written in active and passive voice. Participants selected one sentence from each set and gave a reason for each selection. The participants preferred active over passive 47 to 46 percent of opportunities, but they preferred mixed voice over both, 49 percent. The participants preferred active only for memos to supervisors; in the other five categories they preferred passive or mixed voice. Both males and females preferred mixed voice, and age appeared to influence the choices. They cited context as the most common reason for using passive.

A comprehensive investigation examines the decline and changes that have affected Dallas regional theatre development from the dream of Margo Jones in the 1940s to the proliferation of emerging theatres in 1993. Changing economic conditions, lack of audience support, and shortages of performance space have contributed to an exodus of Dallas actors and artists. Reviewed are measures to reverse this trend, including funding changes, awareness campaigns, improved inter-theatre cooperation, and guidelines for audience development. The study's conclusion notes that theatres do, indeed, have a natural life cycle, but with renewed emphasis on audience development and self-sufficiency, theatres in Dallas can endure and contribute to an enlarged sense of civic pride.

The possibility of a relationship between Adlerian life style, as measured by the Life Style Personality Inventory (LSPI), and the Myers-Briggs Type Indicator (MBTI) was examined by this research. The goal of this study was to clarify the relationship between these instruments to broaden the applicability of both instruments for both research and clinical endeavors. Life style is a concept which is vital to therapeutic intervention from an Adlerian frame of reference. Assessment of life style typically involves lengthy therapist interviews. Both the LSPI and the MBTI are questionnaires designed to measure personality variables. The 117 subjects for this study were solicited from individuals seeking counseling from an urban community counseling center. The individuals served by this agency are primarily those diagnosed with Adjustment Disorders. The LSPI and the MBTI were administered individually to each subject. Means and standard deviations were computed for the seven LSPI themes and the MBTI total. Due to a lack of research support for Theme 4 by the LSPI author, the data for this theme were disregarded. The same research indicated a strong bipolar relationship for Themes 7 and 8 (Displaying Inadequacy and Social Interest), which prompted the inclusion of Theme 8 in subsequent data …

In this study, ADP-ribosylation reactions in the murine myelomonocytic cell line WEHI-3BD+ were investigated.

This thesis examines Albert Speer, minister of armaments in Germany during World War II, and the charges against him during the trial of the major war criminals in Nuremberg, Germany, 1945-1946. This thesis portrays Albert Speer as a good man enticed by the power of his position and subsequently playing a role in the crimes of the Third Reich. Primary sources included the Nuremberg Trial proceedings published by the International Military Tribunal and Speer's books, Inside the Third Reich; Spandau: The Secret Diaries; and Infiltration. The thesis has six chapters: preface, biography, the charges against Speer, the verdict, the aftermath concerning his time in Spandau Prison, and a conclusion. Albert Speer accepted his guilt, yet came to resent his imprisonment and questioned the validity of the trial.

Prolonged exposure to microgravity is known to invoke physiological changes which predispose individuals to orthostatic intolerance upon readaptation to the earth's gravitational field. Attenuated baroreflex responsiveness has been implicated in contributing to this inability to withstand orthostatic stress. To test this hypothesis, eight individuals were exposed to 15 days of simulated microgravity exposure using the 6° head-down bed rest model. Prior to, and after the simulated microgravity exposure, the following were assessed: a) aortic baroreflex function; b) carotid baroreflex function; c) cardiopulmonary baroreflex function; and d) the degree of interaction between the cardiopulmonary and carotid baroreflexes.

It was my intent to find objects that were both historically symbolic and symbolic of the times we live in, and that could be melded into a nineteenth century interior where their presence would be secondary to the overall atmosphere. I wanted to incorporate objects that would function as metaphors or personal symbols as well as historical icons.

The purpose of the present cross-sectional study was to examine the effects of ambiguity of loss and type of caregiver-to-patient relationship on anticipatory grief, negative physical and psychological outcomes associated with grief, and boundary ambiguity in family caregivers of chronically ill patients. Questionnaires were completed by 23 parents of ill children and 30 spouses of ill mates. Using an original and a revised concept for level of ambiguity, partial support was found for the prediction that parents and spouses in high ambiguity of loss circumstances would report more anticipatory grief than those in low ambiguity ones. Contrary to prediction, a slight but nonsignificant trend occurred for parents and spouses in low ambiguity situations to report more negative physical and psychological effects associated with grief as well. Level of ambiguity was not found to impact boundary ambiguity as had been hypothesized. Spouses reported more boundary ambiguity than parents, regardless of level of ambiguity of the loss. Contrary to prediction that parents would report less anticipatory grief and more negative physical and psychological outcomes than spouses, generally, no significant differences were found between the two groups. However, using the original concept of ambiguity, parents did tend to recall more past grief than …

America has adopted as its own the Eden myth, which has provided the mythology of the American dream. This New Garden of America, consequently, has been a masculine garden because of its dependence on the myth of the Fall. Implied in the American dream is the idea of a garden without Eve, or at least without Eve's sin, traditionally associated with sexuality. Our canonical literature has reflected these attitudes of devaluing feminine power or making it a negative force: The Scarlet Letter, Moby-Dick, Adventures of Huckleberry Finn, The Great Gatsby, and The Sound and the Fury. To recreate the Garden myth, Americans have had to reimagine Eve as the idealized virgin, earth mother and life-giver, or as Adam's loyal helpmeet, the silent figurehead. But Eve resists her new roles: Hester Prynne embellishes her scarlet letter and does not leave Boston; the feminine forces in Moby-Dick defeat the monomaniacal masculinity of Ahab; Miss Watson, the Widow Douglas, and Aunt Sally's threat of civilization chase Huck off to the territory despite the beckoning of the feminine river; Daisy retreats unscathed into her "white palace" after Gatsby's death; and Caddy tours Europe on the arm of a Nazi officer long after Quentin's suicide, …

This study involved a geographic information systems (GIS) approach to modeling ground water pollution potential in the Southern Edwards Aquifer Region in Texas. The DRASTIC ground water model was analyzed using two methods. First, the effects of adding land cover data to the drastic model were evaluated. In the second approach, the effects of the removal of DRASTIC variables were evaluated. Six, five, and four variable models were generated and analyzed.

The study addresses whether differently ordered accounts receivable workprograms and task experience relate to differences in judgments, confidence levels, and recall ability. The study also assesses how treated and untreated inexperienced and experienced auditors store and recall accounts receivable workprogram steps in memory in a laboratory environment. Additionally, the question whether different levels of experienced auditors can effectively be manipulated is also addressed.

The primary objective of this dissertation is to determine the factors that have shaped the corporate financial reporting practices in Bahrain. Prior researchers have offered two explanations, environmental factors and cultural importation, for the emergence of financial reporting practices in developing countries. The environmental explanation suggests that a nation's financial reporting practices will be shaped by its socioeconomic structure. The cultural importation explanation states that the desire for international legitimacy creates incentives for developing nation to adopt Western financial reporting practices. Bahrain provided an excellent environment in which to examine the two explanations since its public and closed corporations have similar economic characteristics. Only public corporations are legally required to publish financial reports. I posited that public corporations would try to gain legitimacy for their published reports by adopting Western standards, while closed corporations would not have a similar incentive. I used an interpretive framework to analyze the Bahrain socioeconomic environment and to examine the general financial reporting practices of Bahraini corporations. I found that closed corporations provided data responsive to the Bahraini environment. Public corporations, however, adopted International Accounting Standards. My analysis supported prior researchers7 findings that colonialism, the need for international legitimacy, and international audit firms were important …

The problem of this study concerned factors which influence the funding of college and university noncommercial radio stations as perceived by station directors.

This research examines the assertions made by Johnson and Kaplan (1987) that cost accounting lost relevance after 1925 due to the dominance of financial accounting, to an academic preoccupation with financial accounting, to the disappearance of engineers and to a managerial emphasis on financial measures of net income and earnings per share. Additionally, the research looks at environmental effects on cost accounting, both economic and governmental.

The determination of carbon monoxide is also possible by trapping CO on preconditioned molecular sieve and thermal desorption. Analysis in this case is performed by gas chromatography/mass spectroscopy, although the trapping technique is applicable to other suitable GC techniques.

At times called a philosophy and other times called a process, cutting score methodology is an issue routinely encountered by Industrial/Organizational (I/0) psychologists. Published literature on cutting score methodology appears much more frequently in academic settings than it does in personnel settings where the potential for lawsuits typically occurs more often. With the passage of the 1991 Civil Rights Act, it is no longer legal to use within-group scoring. It has now become necessary for personnel psychologists to develop more acceptable selection methods that fall within established guidelines. Designating cutoff scores with the Angoff method appears to suit many requirements of personnel departments. Several procedures have evolved that suggest enhancing the accuracy and reliability of the Angoff method is possible. The current experiment investigated several such procedures, and found that rater accuracy methods significantly enhance cutoff score reliability and accuracy.

The present work reports the experimental evidence of anomalous energy loss, energy straggling, and the corresponding ion-induced electron emission yields of channeled protons in silicon.

Animations is a composition in six movements (Fish, Seals, Birds, Cats, Zebras, Snakes) for percussion and computer music on tape. One percussionist performs on various percussion instruments: two suspended cymbals, crotales, triangle, vibraphone, glockenspiel, marimba, three bongos, snare drum, field drum, large tom-tom, bass drum, kettle drum, temple blocks and vibraslap. The computer music on tape employs sampled sounds in a MIDI sequencing environment. The melodic and harmonic materials for the piece are derived from a matrix of twelve heptatonic scales. The individual movements are notated using both traditional and proportional notation systems. The score is 37 pages long with a twenty-two page analysis preceding the score. Animations is approximately nine minutes in duration.

In this dissertation the results of Jerrum and Sinclair on the conductance of Markov chains are used to prove that almost all generalized Steinhaus graphs are rapidly mixing and an algorithm for the uniform generation of 2 - (4k + 1,4,1) cyclic Mendelsohn designs is developed.

Whereas conditions have existed for many centuries which served to exclude or marginalize female participation in music, many women have written compositions of musical worth sufficient to justify their contemporary performance. Although most women composers wrote works more fitting for the "salon" than for the concert hall at the turn of the century, Boulanger and Mahler are representative of the few women composers whose complex approach to art song fell within the mainstream of the genre. Many of their accompaniments attain a level of technical difficulty not previously found in women composers' writing. They offer an interesting comparison between nationalities and styles in that they both favored Symbolist texts. However, each represents a different side of the coin in her musical interpretation of Symbolism: Boulanger, Impressionism, and Mahler, Expressionism. In addition, even though their styles involve opposite musical expressions, they both show a strong influence of Wagner in their writing. This study includes background on turn-of-the-century music and musicians encompassing the role of art song among women composers. Symbolism is addressed as it applies to the poets selected by the composers, followed by information regarding the specific musical representation of Symbolist texts in the composers' art songs. The chapter of …

In the middle of his career, Arthur Garfield Dove created a smell yet novel body of landscape assemblages. They illustrate Dove's central interest in evoking nature--its motifs and rhythms--through imaginative associations of organic and man-made materials. These works represent Dove's synthesis of contemporary European stylistic and intellectual ideas as well as American philosophies and concerns. They also reflect the influence of Alfred Stieglitz and his circle and the artist Helen Torr, Dove's second wife. This study examines how Dove used a complex interplay of European theory and technique, American ideas and his own nature-based abstract style to create the landscape assemblages, works that are uniquely independent in the history of American art.

This dissertation primarily concerns performance aspects in compositions for piano and tape, using three specific works as the basis for discussion: Larry Austin's Sonata Concertante, Thomas Clark's Peninsula, and Phil Winsor's Passages. These compositions are representative of the medium as a whole, yet each offers its own unique set of performance problems.

An investigation was undertaken to examine two measures of personality and their utility with adolescent patient populations. The Rorschach, scored using Exner's (1991) Comprehensive System (2nd Ed.), and the Personality Inventory for Youth (PIY; Lachar & Gruber, in press) were explored as to their ability to distinguish inpatients from outpatients, males from females, and diagnostic groups from one another. COP, AG, CDI, DEPI, SCZI, and HVI scores on the Rorschach were utilized, as were the DIS, SOM, FAM, RLTY, WDL, and SSK scores from the PIY.