It was the purpose of this study to purify glyoxalase I and then characterize its physical and kinetic properties. A comparison of the enzyme from the liver of normal and tumor-bearing mice and from the tumor itself was also to be made.

The isolation and purification of triosephosphate isomerase from humanerythrocytes, cardiac and skeletal muscle, liver, and brain has been described. Subsequent isolation and characterization of three isozymes from three tissues was effected.

"The Crystalline Sense" is a composition in one movement for chamber orchestra with the following instrumentation: flute, oboe, clarinet in Bb (doubling bass clarinet in Bb), bassoon, horn in F, trumpet in Bb, trombone, percussion and strings. The composition is approximately nine minutes in length. The goals of the work are (1) to employ intra-sectional practices, (2) to derive all rhythmic ideas from the main themes, (3) to combine certain elements of chromatic, whole tone, and certain triadic structures into a valid compositional technique effective in both vertical and horizontal situations, (4) and to produce a piece of music of moderate difficulty which fully exposes each instrument technically and lyrically.

This investigation is concerned with change in school-directed aspirations of middle and upper-middle-class Jewish public high school students over a fifteen-year period of time.

The process of the organization of the orchestra began with the rise of opera; considered on a broad scale this process divides itself into two periods, the first terminated by the deaths of Bach and Handel (1600-1759) and the second beginning with the complete change of orchestral sound evident in the symphonies of Haydn and Mozart during the second half of the eighteenth century. It is the first of these two periods that witnessed the composers of art music exploiting the natural trumpet, an instrument long associated with court, camp, and field, to the extent that they developed a vast repertoire of trumpet music characterized by its virtuosic technical requirements.

A procedure was developed for the rapid isolation of human phosphoglucose isomerase by substrate-induced elution from cellulose phosphate. The high degree of selectivity of the elution provided homogenous enzyme from erythrocytes after a purification of approximately 30,000-fold with a recovery of approximately 70%. The enzyme was also isolated from other human tissues by a similar procedure.

Procedures for the isolation and characterization of Ascaris glyceraldehyde-3-phosphate dehydrogenase and actin are described. The properties of these proteins, including molecular weights, isoelectric points, kinetics, peptide maps, and amino acid compositions, are strikingly similar to the respective proteins from rabbit muscle.