This Synthesis and Assessment Product (SAP 2.4) focuses on the Climate models. Depletion of the stratospheric ozone layer by human-produced ozone-depleting substances has been recognized as a global environmental issue for more than three decades, and the international effort to address the issue via the United Nations Montreal Protocol marked its 20-year anniversary in 2007. Scientific understanding underpinned the Protocol at its inception and ever since. As scientific knowledge advanced and evolved, the Protocol evolved through amendment and adjustment. Policy-relevant science has documented the rise, and now the beginning decline, of the atmospheric abundances of many ozone-depleting substances in response to actions taken by the nations of the world. Projections are for a return of ozone-depleting chemicals (compounds containing chlorine and bromine) to their "pre-ozone-depletion" (pre-1980) levels by the middle of this century for the midlatitudes; the polar regions are expected to follow suit within 20 years after that. Since the 1980s, global ozone sustained a depletion of about 5 percent in the midlatitudes of both the Northern Hemisphere and Southern Hemisphere, where most of the Earth's population resides; it is now showing signs of turning the corner towards increasing ozone. The large seasonal depletions in the polar regions are …