Purpose: The purpose of this study was to determine if traditional indicators of college readiness were better predictors of students’ first semester college GPA and persistence to the second year of coursework compared to non-traditional indicators of college readiness. Specifically, this study analyzed the predictive validity of high school class rank and ACT/SAT scores compared to that of the psychosocial skills measured by the ACT Engage on students’ first semester college GPA and their likelihood of enrollment in the second year of college coursework. Methodology: Linear and logistic regression models were used to examine the effect of gender, age, ethnicity, socioeconomic status, high school rank, Texas Success Initiative college readiness scores, SAT or ACT scores, and the ten themes of the ACT Engage Inventory (dependent variables), on students’ first semester college GPA and rate of persistence to the second year (independent variables). A sample of 4,379 first semester college freshmen participated in this study. Findings: Results indicated that high school rank, ACT/SAT scores and psychosocial skills measured by the ACT Engage theme academic discipline were accurate predictors of college performance. Results regarding the predictive power of traditional academic and non-traditional psychosocial predictors of persistence were less definitive. Students qualifying for …