The Arabidopsis PAD4 Lipase-Like Domain Is Sufficient for Resistance to Green Peach Aphid (open access)

The Arabidopsis PAD4 Lipase-Like Domain Is Sufficient for Resistance to Green Peach Aphid

Article exploring PAD4 functions in plant defense by expressing the N-terminal PAD4 lipase-like domain (PAD4ᴸᴸᴰ) without its C-terminal EDS1-PAD4 (EP) domain. The authors show that transgenic expression of PAD4ᴸᴸᴰ in Arabidopsis is sufficient for limiting GPA infestation but not for conferring basal and effector-triggered pathogen immunity. This suggests that the C-terminal PAD4 EP domain is necessary for EDS1-dependent immune functions but is dispensable for aphid resistance. Moreover, PAD4ᴸᴸᴰ is not sufficient to interact with EDS1, indicating the PAD4-EP domain is required for stable heterodimerization. These data provide molecular evidence that PAD4 has domain-specific functions.
Date: December 27, 2019
Creator: Dongus, Joram A.; Bhandari, Deepak D.; Patel, Monika; Archer, Lani; Dijkgraaf, Lucas; Shah, Jyoti et al.
System: The UNT Digital Library
Antiviral Activity of Metal-Containing Polymers—Organotin and Cisplatin-Like Polymers (open access)

Antiviral Activity of Metal-Containing Polymers—Organotin and Cisplatin-Like Polymers

This article examines the use of metal-containing polymers as a novel class of antivirals. Polymers containing platinum and to a lesser extent tin, have repeatedly demonstrated antitumor activity in vitro and in vivo against a variety of cell and tumor types. The mechanisms responsible for the antitumor activity include inducing a delay in cell proliferation and sister chromatid exchanges blocking tumor growth.
Date: May 27, 2011
Creator: Roner, Michael R.; Carraher, Charles E., Jr.; Shahi, Kimberly & Barot, Girish
System: The UNT Digital Library
Acid-base regulation in the air-breathing swamp eel (Monopterus albus) at different temperatures (open access)

Acid-base regulation in the air-breathing swamp eel (Monopterus albus) at different temperatures

Article describes study in which researchers characterized the influence of temperature on arterial acid–base balance and intracellular pH (pHi) in the bimodal-breathing swamp eel, Monopterus albus.
Date: February 27, 2018
Creator: Thinh, Phan Vinh; Phuong, Nguyen Thanh; Brauner, Colin J.; Huong, Do Thi Thanh; Wood, Andrew T.; Kwan, Garfield T. et al.
System: The UNT Digital Library
Use of prior odds for missing persons identifications (open access)

Use of prior odds for missing persons identifications

This article discusses the use of DNA typing, likelihood ratios, and prior odds for missing persons identifications.
Date: June 27, 2011
Creator: Budowle, Bruce; Ge, Jianye; Chakraborty, Ranajit & Gill-King, Harrell
System: The UNT Digital Library
Improved Campephiline detection: An experiment conducted with the Magellanic Woodpecker (open access)

Improved Campephiline detection: An experiment conducted with the Magellanic Woodpecker

Article describes a study which tried to determine which of three methods (useing a drumming device to simulate a double‐knock (i.e., territorial acoustical signal), broadcasting a territorial call, or passively listening) best results in a detection of Magellanic Woodpeckers (Campephilus magellanicus ), and if weather variables influence detection probability.
Date: September 27, 2019
Creator: Wynia, Amy L.; Rolland, Virginie & Jiménez, Jaime E.
System: The UNT Digital Library
Lipid signaling in plants (open access)

Lipid signaling in plants

Article on the publication of a volume of articles of researchers addressing various fundamental questions in lipid signaling in plants.
Date: June 27, 2013
Creator: Wang, Xuemin & Chapman, Kent Dean
System: The UNT Digital Library
Development of micro-electrode array based tests for neurotoxicity: assessment of interlaboratory reproducibility with neuroactive chemicals (open access)

Development of micro-electrode array based tests for neurotoxicity: assessment of interlaboratory reproducibility with neuroactive chemicals

Article evaluating the response to the pharmacological compounds Fluoxetine, Muscimol, and Verapamil in primary neuronal cultures. Final conclusions are drawn that MEA technology has a potential for standard in vitro neurotoxicity/neuropharmacology evaluation.
Date: April 27, 2011
Creator: Novellino, A.; Scelfo, Bibiana; Palosaari, T.; Price, A.; Sobanski, Tomasz; Shafer, T.J. et al.
System: The UNT Digital Library
Metabolic Allometry during Development and Metamorphosis of the Silkworm Bombyx mori: Analyses, Patterns, and Mechanisms (open access)

Metabolic Allometry during Development and Metamorphosis of the Silkworm Bombyx mori: Analyses, Patterns, and Mechanisms

This article studies the silkworm Bombyx mori, and hypothesizes that allometric relationships for metabolism both across all developmental stages and within each stage would not reflect conventional scaling coefficients.
Date: January 27, 2010
Creator: Blossman-Myer, Bonnie L. & Burggren, Warren W.
System: The UNT Digital Library
Hawk Mountain: A Conservation Success Story (open access)

Hawk Mountain: A Conservation Success Story

Book review of "Hawk Mountain: A Conservation Success Story" by James J. Brett and Keith L. Bildstein.
Date: April 27, 2016
Creator: Bednarz, James C.
System: The UNT Digital Library
SPHK1 regulates proliferation and survival responses in triple-negative breast cancer (open access)

SPHK1 regulates proliferation and survival responses in triple-negative breast cancer

Article describes study suggesting that the inhibation of sphingosine kinase 1 (SPHK1) can attenuate ERK1/2 and AKT signaling and reduce growth of triple-negative breast cancer (TNBC) cells in vitro and in a xenograft SCID mouse model.
Date: March 27, 2014
Creator: Datta, Arpita; Loo, Ser Yue; Huang, Baohua; Wong, Lingkai; Tan, Sheryl S.L.; Tan, Tuan Zea et al.
System: The UNT Digital Library
Rapid identification of causative insertions underlying Medicago truncatula Tnt1 mutants defective in symbiotic nitrogen fixation from a forward genetic screen by whole genome sequencing (open access)

Rapid identification of causative insertions underlying Medicago truncatula Tnt1 mutants defective in symbiotic nitrogen fixation from a forward genetic screen by whole genome sequencing

This article demonstrates that whole genome sequencing is an efficient approach for identification of causative genes underlying symbiotic nitrogen fixation defective phenotypes in Medicago truncatula Tnt1 insertion mutants obtained via forward genetic screens.
Date: February 27, 2016
Creator: Veerappan, Vijaykumar; Jani, Mehul; Kadel, Khem; Troiani, Taylor; Gale, Ronny; Mayes, Tyler et al.
System: The UNT Digital Library