This report describes the Proposed Legislative Changes Affecting Pharmaceutical Patents on Hatch-Waxman Act. The Hatch-Waxman Act provides the FDA with certain authorities to offer periods of marketing for a pharmaceutical independent of the rights conferred by patents.

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This report summarizes India-US relations from 1947 in preparation for the 2004 National elections, including information about bilateral relations, nuclear testing, separatist movements, and human rights issues.

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Proposals to limit the federal government’s authority to raise taxes have been made several times in recent years. Most frequently, these proposals call for limits on Congress’s ability to pass revenue measures. Typically, limitation proposals would allow increases in tax revenues only under one of two circumstances. First, tax revenues could increase under existing tax laws as a result of economic upturns. Alternatively, they could increase because of a new law, but only if it were passed by a super-majority (typically two-thirds or three-fifths). Questions about how such proposals might be applied in practice have not been clearly answered. Congress has previously considered such proposals in 1996, 1997, 1998, 1999, 2000, and 2001. In each case the proposal has failed to achieve the two-thirds majority necessary for passage. Most recently, the House considered H.J.Res. 96 on June 12, 2002. The measure failed to achieve the necessary two-thirds, 227-178. This report will be updated to reflect any further legislative actions on such proposals.

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In 2001, President Bush established the President’s Commission to Strengthen Social Security to make recommendations on ways to “modernize and restore fiscal soundness to the Social Security system” in accordance with six principles, one of which mandated the creation of voluntary personal retirement accounts. The Commission proposed three alternative reform models. Under all three proposals, workers could choose to invest in personal accounts and have their traditional Social Security benefits reduced by some amount. Model 1 would make no other changes to the program.

A letter report issued by the General Accounting Office with an abstract that begins "Collecting fines ordered for violations of securities and futures laws helps ensure that violators are held accountable for their offenses and may also deter future violations. The requesters asked GAO to evaluate the actions the Securities and Exchange Commission (SEC) and Commodity Futures Trading Commission (CFTC) have taken to address earlier recommendations for improving their collection programs. The committees also asked GAO to update the fines collection rates from previous reports."

A letter report issued by the General Accounting Office with an abstract that begins "Spent nuclear fuel, the used fuel periodically removed from nuclear power reactors, is one of the most hazardous materials made by man. Nuclear power companies currently store 50,000 tons of spent fuel at 72 sites in 33 states. That amount will increase through 2010, when the Department of Energy (DOE) expects to open a permanent repository for this fuel at Yucca Mountain, Nevada. Concerns have been raised since September 11, 2001, that terrorists might target spent fuel. GAO was asked to (1) review federally sponsored studies that assessed the potential health effects of a terrorist attack or a severe accident on spent fuel, either in transit or in storage, and (2) identify options for DOE to further enhance the security of spent fuel during shipping to Yucca Mountain."

A letter report issued by the General Accounting Office with an abstract that begins "With the enactment of the Personal Responsibility and Work Opportunity Reconciliation Act of 1996 (PRWORA), the Congress made sweeping changes to federal policy for needy families. PRWORA ended the Aid to Families with Dependent Children (AFDC) program and created the Temporary Assistance for Needy Families (TANF) block grant to states. The Department of Health and Human Services (HHS) oversees the TANF block grant program, which provides grants to states totaling up to $16.5 billion each year and requires states to maintain a historical level of state spending on welfare reform programs. Under TANF, states have greater flexibility and face greater uncertainty than they did under AFDC. States have greater flexibility to design, finance, and implement programs for low-income families, including determining who is to be served and what services to provide. TANF also emphasizes the transitional nature of assistance and the importance of employment for welfare recipients. Because the amount of the TANF block grant is fixed, as caseloads decline--as they did in all states through the late 1990s--states have had additional resources that they have used to expand their programs, achieve some budgetary savings, and …

Testimony issued by the General Accounting Office with an abstract that begins "GAO has been providing ongoing assistance to the Capitol Preservation Commission and the Senate and House Appropriations Committees in their monitoring and oversight of the Capitol Visitor Center construction project. Given the current decisions facing the Congress, this testimony covers (1) management of the project, (2) the estimated cost for the project, (3) the status of the project's schedule, and (4) actions that Congress and the AOC should consider taking to address funding gaps and other current project issues and risks."

A letter report issued by the General Accounting Office with an abstract that begins "The U.S.-South Korean Land Partnership Plan (LPP), signed in March 2002, was designed to consolidate U.S. installations, improve combat readiness, enhance public safety, and strengthen the U.S.-South Korean alliance by addressing some of the causes of periodic tension associated with the U.S. presence in South Korea. The Senate report on military construction appropriations for fiscal year 2003 directed GAO to review the LPP. GAO adjusted its review to also address the effect of ongoing reassessments of U.S. overseas presence upon the LPP and other infrastructure needs. In this report, GAO assessed (1) the scope of the LPP, (2) the implications on the LPP and other construction projects of proposals to change basing in South Korea, and (3) implementation challenges associated with the LPP that could affect future U.S. military construction projects in South Korea."

A letter report issued by the General Accounting Office with an abstract that begins "Since July 1998, GAO has reported numerous times on nursing home quality-of-care issues and identified significant weaknesses in federal and state oversight. GAO was asked to assess the extent of the progress made in improving the quality of care provided by nursing homes to vulnerable elderly and disabled individuals, including (1) trends in measured nursing home quality, (2) state responses to previously identified weaknesses in their survey, complaint, and enforcement activities, and (3) the status of oversight and quality improvement efforts by the Centers for Medicare & Medicaid Services (CMS)."

Testimony issued by the General Accounting Office with an abstract that begins "Since September 11, 2001, visa operations have played an increasingly important role in ensuring the national security of the United States. The Departments of State, Homeland Security, and Justice, as well as other agencies, are involved in the visa process. Each plays an important role in making security decisions so that potential terrorists do not enter the country. In two GAO reports, we assessed the effectiveness of the visa process as an antiterrorism tool."

A letter report issued by the General Accounting Office with an abstract that begins "Prompted by a desire to reverse declining audience trends and to support the war on terrorism, the Broadcasting Board of Governors (BBG), the agency responsible for U.S. international broadcasting, began developing its new strategic approach to international broadcasting in July 2001. This approach emphasizes the need to reach mass audiences by applying modern broadcast techniques and strategically allocating resources to focus on high-priority markets. GAO was asked to examine (1) whether recent program initiatives have adhered to the Board's new strategic approach to broadcasting, (2) how the approach's effectiveness will be assessed, and (3) what critical challenges the Board faces in executing its strategy and how these challenges will be addressed."

A letter report issued by the General Accounting Office with an abstract that begins "The Department of Defense (DOD) is pursuing a new initiative involving a core competency approach for making sourcing decisions--that is, sourcing decisions based on whether the function is core to the agency's warfighting mission. In determining how to best perform non-core functions, DOD's position is that its components should look beyond just the use of public-private competitions under Office of Management and Budget (OMB) Circular A-76 in making sourcing decisions, and consider other alternatives such as partnering or employee stock ownership. GAO was asked to assess (1) the department's progress in assessing its core functions as a basis for sourcing decisions, (2) the plans and progress DOD has made in identifying and implementing alternatives to A-76, and (3) the current status of DOD's A-76 program."

Testimony issued by the General Accounting Office with an abstract that begins "In 1986, the United States entered into a Compact of Free Association with the Pacific Island nations of the Federated States of Micronesia, or FSM, and the Republic of the Marshall Islands, or RMI. The Compact provided about $2.1 billion in U.S. funds, supplied by the Department of the Interior, over 17 years (1987-2003) to the FSM and the RMI. These funds were intended to advance economic development. In a past report, GAO found that this assistance did little to advance economic development in either country, and accountability over funding was limited. The Compact also established U.S. defense rights and obligations in the region and allowed for migration from both countries to the United States. The three parties recently renegotiated expiring economic assistance provisions of the Compact in order to provide an additional 20 years of assistance (2004-2023). In addition, the negotiations addressed defense and immigration issues. The House International Relations and Resources Committees requested that GAO report on Compact negotiations."

Testimony issued by the General Accounting Office with an abstract that begins "Polar-orbiting environmental satellites provide data and imagery that are used by weather forecasters, climatologists, and the military to map and monitor changes in weather, climate, the ocean, and the environment. The current polar satellite program is a complex infrastructure that includes two satellite systems, supporting ground stations, and four central data processing centers. In the future, the National Polar-orbiting Operational Environmental Satellite System (NPOESS) is to merge the two current satellite systems into a single state-of-the-art environment monitoring satellite system. This new $7 billion satellite system is considered critical to the United States' ability to maintain the continuity of data required for weather forecasting and global climate monitoring through the year 2018. In its testimony GAO was asked, among other topics, to discuss risks to the success of the NPOESS deployment."

The performance of the SuperLig(R) 644 resin loading and elution was evaluated at 25, 35, and 45 degree C using a single-column containing 2.25 g of oven-dry, hydrogen form of SuperLig(R) 664 resin. A simulated Envelope A solution was used to mimic the composition of low-activity waste solution from Tank 241-AN-105 supernate in the Hanford Site waste tank. The simulant was spiked with small quantities of trace metals (cadmium, chromium, iron, and lead) to evaluate the effects of these metals on cesium sorption. The results from column tests performed at 25, 35, and 45 degree C showed that more than 100 BVs of simulated Envelope A solution could be processed at each temperature before 50 percent breakthrough of the cesium occurred.

Roof bolting is the most popular method for underground openings in the mining industry, especially in the bedded deposits such as coal, potash, salt etc. In fact, all U.S. underground coal mine entries are roof-bolted as required by law. However, roof falls still occur frequently in the roof bolted entries. The two possible reasons are: the lack of knowledge of and technology to detect the roof geological conditions in advance of mining, and lack of roof bolting design criteria for modern roof bolting systems. This research is to develop a method for predicting the roof geology and stability condition in real time during roof bolting operation. Based on such information, roof bolting design criteria for modern roof bolting systems will be developed for implementation in real time. In this quarter, the field, theoretical and programming works have been performed toward achieving the research goals set in the proposal. The selected site and the field testing plan enabled us to test all three aspects of roof geological features. The development of the data interpretation methodologies and the geology mapping computer program have also been preceding well.

While commodity computing and graphics hardware has increased in capacity and dropped in cost, it is still quite difficult to make effective use of such systems for general-purpose parallel visualization and graphics. We describe the results of a recent project that provides a software infrastructure suitable for general-purpose use by parallel visualization and graphics applications. Our work combines and extends two technologies: Chromium, a stream-oriented framework that implements the OpenGL programming interface; and OpenRM Scene Graph, a pipelined-parallel scene graph interface for graphics data management. Using this combination, we implement a sort-first, distributed memory, parallel volume rendering application. We describe the performance characteristics in terms of bandwidth requirements and highlight key algorithmic considerations needed to implement the sort-first system. We characterize system performance using a distributed memory parallel volume rendering application, a nd present performance gains realized by using scene specific knowledge to accelerate rendering through reduced network bandwidth. The contribution of this work is an exploration of general-purpose, sort-first architecture performance characteristics as applied to distributed memory, commodity hardware, along with a description of the algorithmic support needed to realize parallel, sort-first implementations.

Run-II at Fermilab is progressing steadily. In the Run-II scheme, 36 antiproton bunches collide with 36 proton bunches at the CDF and D0 interaction regions in the Tevatron at 980 GeV per beam. The current status and performance of the Fermilab Accelerator complex is reviewed. The plan for Run-II, accelerator upgrades and integration of the Recycler in the accelerator chain will be presented.

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Two biodegradation models are developed to represent natural attenuation of fuel-hydrocarbon contaminants as observed in a comprehensive natural-gradient tracer test in a heterogeneous aquifer on the Columbus Air Force Base in Mississippi. The first, a first-order mass loss model, describes the irreversible losses of BTEX and its individual components, i.e., benzene (B), toluene (T), ethyl benzene (E), and xylene (X). The second, a reactive pathway model, describes sequential degradation pathways for BTEX utilizing multiple electron acceptors, including oxygen, nitrate, iron and sulfate, and via methanogenesis. The heterogeneous aquifer is represented by multiple hydraulic conductivity (K) zones delineated on the basis of numerous flowmeter K measurements. A direct propagation artificial neural network (DPN) is used as an inverse modeling tool to estimate the biodegradation rate constants associated with each of the K zones. In both the mass loss model and the reactive pathway model, the biodegradation rate constants show an increasing trend with the hydraulic conductivity. The finding of correlation between biodegradation kinetics and hydraulic conductivity distributions is of general interest and relevance to characterization and modeling of natural attenuation of hydrocarbons in other petroleum-product contaminated sites.