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2003 Biology and Biotechnology Research Program Overview and Highlights (open access)

2003 Biology and Biotechnology Research Program Overview and Highlights

LLNL conducts multidisciplinary bioscience to fill national needs. Our primary roles are to: develop knowledge and tools which enhance national security, including biological, chemical and nuclear capabilities, and energy and environmental security; develop understanding of genetic and biochemical processes to enhance disease prevention, detection and treatment; develop unique biochemical measurement and computational modeling capabilities which enable understanding of biological processes; and develop technology and tools which enhance healthcare. We execute our roles through integrated multidisciplinary programs that apply our competencies in: microbial and mammalian genomics--the characterization of DNA, the genes it encodes, their regulation and function and their role in living systems; protein function and biochemistry - the structure, function, and interaction of proteins and other molecules involved in the integrated biochemical function of the processes of life; computational modeling and understanding of biochemical systems--the application of high-speed computing technology to simulate and visualize complex, integrated biological processes; bioinformatics--databasing, networking, and analysis of biological data; and bioinstrumentation--the application of physical and engineering technologies to novel biological and biochemical measurements, laboratory automation, medical device development, and healthcare technologies. We leverage the Laboratory's exceptional capabilities in the physical, computational, chemical, environmental and engineering sciences. We partner with industry and universities to utilize …
Date: March 1, 2003
Creator: Prange, C
Object Type: Report
System: The UNT Digital Library
78th Texas Legislature, Regular Session, House Bill 839, Chapter 469 (open access)

78th Texas Legislature, Regular Session, House Bill 839, Chapter 469

Bill introduced by the Texas House of Representatives relating to a limitation on the future employment of a board member of certain water-related districts.
Date: 2003-03/2003-06
Creator: Texas. Legislature. House of Representatives.
Object Type: Legislative Document
System: The Portal to Texas History
78th Texas Legislature, Regular Session, House Bill 850, Chapter 85 (open access)

78th Texas Legislature, Regular Session, House Bill 850, Chapter 85

Bill introduced by the Texas House of Representatives relating to the regulation of the sale of a tow truck at a new motor vehicle show or exhibition.
Date: 2003-03/2003-05
Creator: Texas. Legislature. House of Representatives.
Object Type: Legislative Document
System: The Portal to Texas History
78th Texas Legislature, Regular Session, House Bill 858, Chapter 62 (open access)

78th Texas Legislature, Regular Session, House Bill 858, Chapter 62

Bill introduced by the Texas House of Representatives relating to the salaries of certain judges in Tarrant County.
Date: 2003-03/2003-05
Creator: Texas. Legislature. House of Representatives.
Object Type: Legislative Document
System: The Portal to Texas History
78th Texas Legislature, Regular Session, House Bill 873, Chapter 472 (open access)

78th Texas Legislature, Regular Session, House Bill 873, Chapter 472

Bill introduced by the Texas House of Representatives relating to the rural volunteer fire department insurance program.
Date: 2003-03/2003-06
Creator: Texas. Legislature. House of Representatives.
Object Type: Legislative Document
System: The Portal to Texas History
Abilene Philharmonic Playbill: March 1-April 26, 2003 (open access)

Abilene Philharmonic Playbill: March 1-April 26, 2003

Program for an Abilene Philharmonic concert that ran from March 1st to April 26th (classical concerts) during the 52nd season. It includes information about the pieces performed, artists and musicians, and advertising from local companies.
Date: March 2003
Creator: Abilene Philharmonic
Object Type: Pamphlet
System: The Portal to Texas History
Advanced Petroleum-Based Fuels -- Diesel Emissions Control Project (APBF-DEC) (open access)

Advanced Petroleum-Based Fuels -- Diesel Emissions Control Project (APBF-DEC)

Annual progress report of the Advanced Petroleum-based fuels-Diesel Emissions Control Project. Contains information on 5 test projects to determine the best combinations of low-sulfur diesel fuels, lubricants, diesel engines, and emission control systems to meet projected emissions standards.
Date: March 1, 2003
Creator: unknown
Object Type: Report
System: The UNT Digital Library
Aeronautics Star, Volume 4, Number 2, March/April 2003 (open access)

Aeronautics Star, Volume 4, Number 2, March/April 2003

Bimonthly newsletter published for employees of Lockheed Martin Aeronautics Co. containing work-related information, updates about employees, and other news.
Date: March 2003
Creator: Lockheed Martin Astronautics Corporation
Object Type: Journal/Magazine/Newsletter
System: The Portal to Texas History
The Age, Volume 26, Number 3, March 2003 (open access)

The Age, Volume 26, Number 3, March 2003

Monthly publication containing information related to Chambers County, Texas, including current events of the Chambers County Historical Commission, the Wallisville Heritage Park, and the Chambers County historical and genealogical societies; reprinted newspaper articles about county events and citizens; and historical news and records.
Date: March 2003
Creator: Wallisville Heritage Park (Organization)
Object Type: Journal/Magazine/Newsletter
System: The Portal to Texas History
Alkaline-Surfactant-Polymer Flooding and Reservoir Characterization of the Bridgeport and Cypress Reservoirs of the Lawrence Field (open access)

Alkaline-Surfactant-Polymer Flooding and Reservoir Characterization of the Bridgeport and Cypress Reservoirs of the Lawrence Field

Feasibility of alkaline-surfactant-polymer flood for the Lawrence Field in Lawrence County, Illinois is being studied. Two injected formulations are being designed; one for the Bridgeport A and Bridgeport B reservoirs and one for Cypress and Paint Creek reservoirs. Fluid-fluid and coreflood evaluations have developed a chemical solution that produces incremental oil in the laboratory from the Cypress and Paint Creek reservoirs. A chemical formulation for the Bridgeport A and Bridgeport B reservoirs is being developed. A reservoir characterization study is being done on the Bridgeport A, B, & D sandstones, and on the Cypress sandstone. The study covers the pilot flood area and the Lawrence Field.
Date: March 1, 2003
Creator: Pitts, Malcolm; Damm, Ron & Seyler, Bev
Object Type: Report
System: The UNT Digital Library
Alkaline-Surfactant-Polymer Flooding and Reservoir Characterization of the Bridgeport and Cypress Reservoirs of the Lawrence Field Quarterly Report: April-June 2002 (open access)

Alkaline-Surfactant-Polymer Flooding and Reservoir Characterization of the Bridgeport and Cypress Reservoirs of the Lawrence Field Quarterly Report: April-June 2002

Feasibility of alkaline-surfactant-polymer flood for the Lawrence Field in Lawrence County, Illinois is being studied. Two injected formulations are being designed; one for the Bridgeport A and Bridgeport B reservoirs and one for Cypress and Paint Creek reservoirs. Fluid-fluid and coreflood evaluations have developed a chemical solution that produces incremental oil in the laboratory from the Cypress and Paint Creek reservoirs. A chemical formulation for the Bridgeport A and Bridgeport B reservoirs is being developed. A reservoir characterization study is being done on the Bridgeport A, B, & D sandstones, and on the Cypress sandstone. The study covers the pilot flood area and the Lawrence Field.
Date: March 1, 2003
Creator: Pitts, Malcolm; Damm, Ron & Seyler, Bev
Object Type: Report
System: The UNT Digital Library
Alternative Fuel News, Vol. 6, No. 4 (open access)

Alternative Fuel News, Vol. 6, No. 4

Quarterly magazine with articles on Alternate Fuel Vehicles (AFVs) in India, alternative fuels for emergency preparedness, and testing of propane vehicles by UPS. Also an interview of author Jeremy Rifkin on how alternative fuels provide pathways to hydrogen.
Date: March 1, 2003
Creator: unknown
Object Type: Text
System: The UNT Digital Library
Amorphous Diamond In Vivo and In Vitro Evaluation (open access)

Amorphous Diamond In Vivo and In Vitro Evaluation

None
Date: March 1, 2003
Creator: FRIEDMANN, THOMAS A.; SULLIVAN, JOHN P.; LAVAN, DAVID A.; KOHANE, DANIEL & SULLIVAN, JOHN P.
Object Type: Report
System: The UNT Digital Library
Analytical Modeling of Fission Product Releases by Diffusion from Multicoated Fuel Particles (open access)

Analytical Modeling of Fission Product Releases by Diffusion from Multicoated Fuel Particles

Three levels of fission product diffusional release models are solved exactly. First, the Booth model for a homogeneous uncoated spherical fuel particle is presented and an improved implementation is suggested. Second, the release from a fuel particle with a single barrier layer is derived as a simple alternative to account for a coating layer. Third, the general case of release from a multicoated fuel particle is derived and applied to a TRISO-coated fuel. Previous approaches required approximate numerical solutions for the case of an arbitrary number of coatings with arbitrary diffusivities and arbitrary coating interface conditions.
Date: March 1, 2003
Creator: GELBARD, FRED
Object Type: Report
System: The UNT Digital Library
Annual Coded Wire Tag Program; Oregon Stock Assessment, Annual Report 2002. (open access)

Annual Coded Wire Tag Program; Oregon Stock Assessment, Annual Report 2002.

This annual report is in fulfillment of contract obligations with Bonneville Power Administration which is the funding source for the Oregon Department of Fish and Wildlife project 'Annual Stock Assessment - Coded Wire Tag Program (ODFW)'. Results for the 2002 contract period: Objective 1 - Over 1 million juvenile salmon were coded-wire by this program (Table 1). This accounted for about 20% of the fish ODFW coded-wire tagged in 2002 for release in the Columbia Basin; Objective 2 - ODFW recovered and processed over 50,000 snouts collected from coded-wire tagged fish (Table 2); Objective 3 - The survival data summarized below includes results for coded-wire groups funded by this program as well as coded-wire groups funded from other sources; Objective 4 - The last returns of experimental groups of coho marked with VIE tags occurred in 2002 at Sandy Hatchery. This sampling showed that 26 of 67 jack coho and 1 of 2,223 adult coho VIE marked as juveniles retained the VIE mark as adults.
Date: March 1, 2003
Creator: Lewis, Mark; Mallette, Christine & Murray, William
Object Type: Report
System: The UNT Digital Library
An Application of Bayesian Methods for Combining Data from Different Test Modalities (open access)

An Application of Bayesian Methods for Combining Data from Different Test Modalities

This report documents the research into the application of hierarchical Bayesian methods for characterizing the population failure rate (i.e. probability of defect) of an electronic component based on test data from a number of different test modalities. Classical statistical methods, those based on a frequency approach permit the combination of point estimates but stumble when characterizing the resulting confidence limits. Classical Bayesian methods permit the logical combination of test data, but are not fully efficient in incorporating all available information. In particular, classical Bayesian methods assume that the articles under test are not related in any manner even though the articles may be identical. Alternatively, hierarchical Bayesian methods permit the relationship between test articles to be explicitly included in the analysis. Data from four different test modalities are considered in the analysis. Comparisons are made between the current analysis approach (using traditional statistical methods), classical Bayesian methods and a hierarchical Bayesian approach.
Date: March 1, 2003
Creator: Robinson, David G. & Chang, I. Ann
Object Type: Report
System: The UNT Digital Library
Applied Phyto-Remediation Techniques Using Halophytes for Oil and Brine Spill Scars (open access)

Applied Phyto-Remediation Techniques Using Halophytes for Oil and Brine Spill Scars

Produced salt water from historical oil and gas production was often managed with inadequate care and unfortunate consequences. In Kansas, the production practices in the 1930's and 1940's--before statewide anti-pollution laws--were such that fluids were often produced to surface impoundments where the oil would segregate from the salt water. The oil was pumped off the pits and the salt water was able to infiltrate into the subsurface soil zones and underlying bedrock. Over the years, oil producing practices were changed so that segregation of fluids was accomplished in steel tanks and salt water was isolated from the natural environment. But before that could happen, significant areas of the state were scarred by salt water. These areas are now in need of economical remediation. Remediation of salt scarred land can be facilitated with soil amendments, land management, and selection of appropriate salt tolerant plants. Current research on the salt scars around the old Leon Waterflood, in Butler County, Kansas show the relative efficiency of remediation options. Based upon these research findings, it is possible to recommend cost efficient remediation techniques for slight, medium, and heavy salt water damaged soil. Slight salt damage includes soils with Electrical Conductivity (EC) values of 4.0 …
Date: March 1, 2003
Creator: Korphage, M.L.; Langhus, Bruce G. & Campbell, Scott
Object Type: Report
System: The UNT Digital Library
Atomic Force Microscopy Studies of Lipophosphoglycan (LPG) Molecules in Lipid Bilayers (open access)

Atomic Force Microscopy Studies of Lipophosphoglycan (LPG) Molecules in Lipid Bilayers

Lipophosphoglycan (LPG) is a lypopolysaccharide found on the surface of the parasite Leishmania donovani that is thought to play an essential role in the infection of humans with leishamniasis. LPG acts as an adhesion point for the parasite to the gut of the sand fly, whose bite is responsible for transmitting the disease. In addition, LPG acts to inhibit protein kinase C (PKC) in the human macrophage, possibly by structural changes in the membrane. The Ca{sup 2+} ion is believed to play a role in the infection cycle, acting both as a crosslinker between LPG molecules and by playing a part in modulating PKC activity. To gain insight into the structure of LPG within a supported lipid membrane and into the structural changes that occur due to Ca{sup 2+} ions, we have employed the atomic force microscope (AFM). We have observed that the LPG molecules inhibit bilayer fusion, resulting in bilayer islands on the mica surface. One experiment suggests that the LPG molecules are parallel to the mica surface and that the structure of the LPG changes upon addition of Ca{sup 2+}, with an increase in the height of the LPG molecules from the bilayer surface and an almost complete …
Date: March 1, 2003
Creator: LAST, JULIE A.; HUBER, TINA; SASAKI, DARRYL Y.; SALVATORE, BRIAN & TURCO, SALVATORE J.
Object Type: Report
System: The UNT Digital Library
An Audit of the Basic Financial Statements of the Office of the Fire Fighters' Pension Commissioner for the Fiscal Year Ended August 31, 2002 (open access)

An Audit of the Basic Financial Statements of the Office of the Fire Fighters' Pension Commissioner for the Fiscal Year Ended August 31, 2002

Report of the Texas State Auditor's Office related to an opinion on the Office of the Fire Fighters' Pension Commissioner's (Commission) basic financial statements in accordance with auditing standards generally accepted in the US.
Date: March 2003
Creator: Texas. Office of the State Auditor.
Object Type: Report
System: The Portal to Texas History
An Audit Report on Compliance with Benefits Proportional by Fund Requirements at 20 State Entities (open access)

An Audit Report on Compliance with Benefits Proportional by Fund Requirements at 20 State Entities

Report of the Texas State Auditor's Office related to selected state entities' compliance or noncompliance with Salaries to be Proportional by Fund Requirements in the General Appropriations Act.
Date: March 2003
Creator: Texas. Office of the State Auditor.
Object Type: Report
System: The Portal to Texas History
An Audit Report on the Children's Health Insurance Program at the Health and Human Services Commission (open access)

An Audit Report on the Children's Health Insurance Program at the Health and Human Services Commission

Report of the Texas State Auditor's Office related to determining whether projected savings from the Health and Human Services Commission's in-house management of the Children's Health Insurance Program (CHIP) drug benefit were realistic and attainable; whether the Commission used accurate data and reasonable assumptions when developing initial HMO premiums for CHIP; and whether the Commission established health maintenance organization (HMO) premiums for the second year of CHIP based on reliable, accurate data and a comprehensive analysis.
Date: March 2003
Creator: Texas. Office of the State Auditor.
Object Type: Report
System: The Portal to Texas History
An Audit Report on the Commission on State Emergency Communications' Disbursement of State Funds (open access)

An Audit Report on the Commission on State Emergency Communications' Disbursement of State Funds

Report of the Texas State Auditor's Office related to determining whether the Commission on State Emergency Communications disburses state funds to the regional planning commissions (RPCs) only after RPCs spend all local funds.
Date: March 2003
Creator: Texas. Office of the State Auditor.
Object Type: Report
System: The Portal to Texas History
An Audit Report on the Department of Health's Implementation of a Business Improvement Plan (open access)

An Audit Report on the Department of Health's Implementation of a Business Improvement Plan

Report of the Texas State Auditor's Office related to the failure of the Department of Health to make significant progress in implementing important initiatives related to its core administrative support functions in its Business Improvement Plan, which has contributed to serious ongoing weaknesses in the Department's financial operations.
Date: March 2003
Creator: Texas. Office of the State Auditor.
Object Type: Report
System: The Portal to Texas History
An Audit Report on the Department of Transportation's Management of State Highway Fund 6 (open access)

An Audit Report on the Department of Transportation's Management of State Highway Fund 6

Report of the Texas State Auditor's Office related to determining whether the Department of Transportation is managing the daily balance in the State Highway Fund (Fund 6) to minimize excess balances while ensuring that funds are available for prompt payments to contractors, providing accurate and useful financial information on Fund 6 activities to the Legislature and other external customers, and complying with the capital budget provisions of the General Appropriations Act.
Date: March 2003
Creator: Texas. Office of the State Auditor.
Object Type: Report
System: The Portal to Texas History