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04-ERD-052-Final Report
Generating the sequence of the human genome represents a colossal achievement for science and mankind. The technical use for the human genome project information holds great promise to cure disease, prevent bioterror threats, as well as to learn about human origins. Yet converting the sequence data into biological meaningful information has not been immediately obvious, and we are still in the preliminary stages of understanding how the genome is organized, what are the functional building blocks and how do these sequences mediate complex biological processes. The overarching goal of this program was to develop novel methods and high throughput strategies for determining the functions of ''anonymous'' human genes that are evolutionarily deeply conserved in other vertebrates. We coupled analytical tool development and computational predictions regarding gene function with novel high throughput experimental strategies and tested biological predictions in the laboratory. The tools required for comparative genomic data-mining are fundamentally the same whether they are applied to scientific studies of related microbes or the search for functions of novel human genes. For this reason the tools, conceptual framework and the coupled informatics-experimental biology paradigm we developed in this LDRD has many potential scientific applications relevant to LLNL multidisciplinary research in bio-defense, …
Date:
February 26, 2007
Creator:
Loots, G. G.; Ovcharenko, I.; Collette, N.; Babu, P.; Chang, J.; Stubbs, L. et al.
Object Type:
Report
System:
The UNT Digital Library
9-11 Commission Hearing #7, January 26, 2004, Part 1
Recording of the seventh public hearing held by the National Commission on Terrorist Attacks upon the United States on January 26-27 at the Hart Senate Office Building in Washington, D.C. This hearing specifically addresses the topics of border and aviation security. In addition, several staff statements from the Commission were delivered during the course of the proceedings. This section includes the first staff statement on the entry of the 9/11 hijackers into the United States and the first panel on the border security system prior to September 11, with testimony from Mary A. Ryan and Doris Meissner.
Date:
January 26, 2004
Creator:
National Commission on Terrorist Attacks upon the United States
Object Type:
Video
System:
The UNT Digital Library
9-11 Commission Hearing #7, January 26, 2004, Part 2
Recording of the seventh public hearing held by the National Commission on Terrorist Attacks upon the United States on January 26-27 at the Hart Senate Office Building in Washington, D.C. This hearing specifically addresses the topics of border and aviation security. In addition, several staff statements from the Commission were delivered during the course of the proceedings. This section includes the panel on an incident in Florida with testimony from Jose E. Mendelez-Perez.
Date:
January 26, 2004
Creator:
National Commission on Terrorist Attacks upon the United States
Object Type:
Video
System:
The UNT Digital Library
9-11 Commission Hearing #7, January 26, 2004, Part 3
Recording of the seventh public hearing held by the National Commission on Terrorist Attacks upon the United States on January 26-27 at the Hart Senate Office Building in Washington, D.C. This hearing specifically addresses the topics of border and aviation security. In addition, several staff statements from the Commission were delivered during the course of the proceedings. This section includes the staff statement on three 9/11 hijackers: identification, watchlisting, and tracking, in addition to the third panel on visas and watchlisting today, with testimony from Maura Harty, Russell E. Travers, and Donna A. Buccella.
Date:
January 26, 2004
Creator:
National Commission on Terrorist Attacks upon the United States
Object Type:
Video
System:
The UNT Digital Library
9-11 Commission Hearing #7, January 26, 2004, Part 4
Recording of the seventh public hearing held by the National Commission on Terrorist Attacks upon the United States on January 26-27 at the Hart Senate Office Building in Washington, D.C. This hearing specifically addresses the topics of border and aviation security. In addition, several staff statements from the Commission were delivered during the course of the proceedings. This section includes the fourth panel on the response to September 11 on the borders with testimony from James Ziglar, Robert C. Bonner, and Peter F. Verga.
Date:
January 26, 2004
Creator:
National Commission on Terrorist Attacks upon the United States
Object Type:
Video
System:
The UNT Digital Library
A 15-T Pulsed Solenoid for a High-Power Target Experiment
The MERIT experiment, to be run at CERN in 2007, is a proof-of-principle test for a target system that converts a 4-MW proton beam into a high-intensity muon beam for either a neutrino factory complex or a muon collider. The target system is based on a free mercury jet that intercepts an intense proton beam inside a 15-T solenoidal magnetic field. Here, we describe the design and initial performance of the 15-T, liquid-nitrogen-precooled, copper solenoid magnet.
Date:
June 26, 2006
Creator:
Kirk, H. G.; Efthymiopoulos, I.; Fabich, A.; Haug, R.; Titus, P.; McDonald, K. T. et al.
Object Type:
Article
System:
The UNT Digital Library
222-S LABORATORY FUME HOOD TESTING STUDY
The 222-S Laboratory contains 155 active fume hoods that are used to support analytical work with radioactive and/or toxic materials. The performance of a fume hood was brought into question after employees detected odors in the work area while mixing chemicals within the subject fume hood. Following the event, testing of the fume hood was conducted to assess the performance of the fume hood. Based on observations from the testing, it was deemed appropriate to conduct performance evaluations of other fume hoods within the laboratory.
Date:
March 26, 2007
Creator:
Ruelas, B. H.
Object Type:
Report
System:
The UNT Digital Library
300 Area D4 Project 2nd Quarter FY06 Building Completion Report
This report documents the deactivation, decontamination, decommissioning, and demolition of 16 buildings in the 300 Area of the Hanford Site. The D4 of these facilities included characterization, engineering, removal of hazardous and radiologically contaminated materials, equipment removal, utility disconnection, deactivation, decontamination, demolition of the structure, and stabilization or removal of the remaining slab and foundation as appropriate.
Date:
June 26, 2006
Creator:
Smith, David S.
Object Type:
Report
System:
The UNT Digital Library
300 Area Uranium Leach and Adsorption Project
The objective of this study was to measure the leaching and adsorption characteristics of uranium in six near-surface sediment samples collected from the 300 Area of the Hanford Site. Scanning electron micrographs of the samples showed that the uranium contamination in the sediments is most likely present as co-precipitates and/or discrete uranium particles. Molecular probe techniques also confirm the presence of crystalline discrete uranium bearing phases. In all cases, the uranium is present as oxidized uranium (uranyl [U(VI)]). Results from the column leach tests showed that uranium leaching did not follow a constant solubility paradigm. Four of the five contaminated sediments showed a large near instantaneous release of a few percent of the total uranium followed by a slower continual release. Steady-state uranium leachate concentrations were never measured and leaching characteristics and trends were not consistent among the samples. Dissolution kinetics were slow, and the measured leach curves most likely represent a slow kinetically controlled desorption or dissolution paradigm. Batch adsorption experiments were performed to investigate the effect of pH and uranium and carbonate solution concentrations on uranium adsorption onto the uncontaminated sediment. Uranium adsorption Kd values ranged from 0 to > 100 ml/g depending on which solution parameter was …
Date:
November 26, 2002
Creator:
Serne, R. Jeffrey; Brown, Christopher F.; Schaef, Herbert T.; Pierce, Eric M.; Lindberg, Michael J.; Wang, Zheming et al.
Object Type:
Report
System:
The UNT Digital Library
481 Form Letters from concerned citizens supporting Niagara Falls Air Force Reserve and Guard Base
Community Correspondence - 481 Form Letters from concerned citizens supporting Niagara Falls Air Force Reserve and Guard Base
Date:
July 26, 2005
Creator:
unknown
Object Type:
Letter
System:
The UNT Digital Library
525 Form Letters from concerned citizens supporting Niagara Falls Air Force Reserve and Guard Base
Community Correspondence - 525 Form Letters from concerned citizens supporting Niagara Falls Air Force Reserve and Guard Base
Date:
July 26, 2005
Creator:
unknown
Object Type:
Letter
System:
The UNT Digital Library
527 Organizations: How the Differences in Tax and Election Laws Permit Certain Organizations to Engage in Issue Advocacy without Public Disclosure and Proposals for Change
This report compares the tax and election laws relating to political organizations and political committees in an attempt to highlight the differences between them, and discusses some of the proposals in the 106th Congress to require additional reporting by organizations engaging in political activities. This report does not address the taxation of other tax-exempt organizations making political expenditures taxable under IRC § 527. The report will be updated as new proposals are reported.
Date:
June 26, 2000
Creator:
Morris, Marie B.
Object Type:
Report
System:
The UNT Digital Library
549 Form Letters from concerned citizens supporting Niagara Falls Air Force Reserve and Guard Base
Community Correspondence - 549 Form Letters from concerned citizens supporting Niagara Falls Air Force Reserve and Guard Base
Date:
July 26, 2005
Creator:
unknown
Object Type:
Letter
System:
The UNT Digital Library
550 Form Letters from concerned citizens supporting Niagara Falls Air Force Reserve and Guard Base
Community Correspondence - 550 Form Letters from concerned citizens supporting Niagara Falls Air Force Reserve and Guard Base
Date:
July 26, 2005
Creator:
unknown
Object Type:
Letter
System:
The UNT Digital Library
555 Form Letters from concerned citizens supporting Niagara Falls Air Force Reserve and Guard Base
Community Correspondence - 555 Form Letters from concerned citizens supporting Niagara Falls Air Force Reserve and Guard Base
Date:
July 26, 2005
Creator:
unknown
Object Type:
Letter
System:
The UNT Digital Library
556 letters from concerened citizens supporting Niagara Falls Air Force Reserve Base
Community Correspondence - 556 letters from concerened citizens supporting Niagara Falls Air Force Reserve Base
Date:
July 26, 2005
Creator:
unknown
Object Type:
Letter
System:
The UNT Digital Library
565 Form Letters from concerned citizens supporting Niagara Falls Air Force Reserve and Guard Base
Community Correspondence - 565 Form Letters from concerned citizens supporting Niagara Falls Air Force Reserve and Guard Base
Date:
July 26, 2005
Creator:
unknown
Object Type:
Letter
System:
The UNT Digital Library
565 Form Letters from concerned citizens supporting Niagara Falls Air Force Reserve and Guard Base
Community Correspondence - 565 Form Letters from concerned citizens supporting Niagara Falls Air Force Reserve and Guard Base
Date:
July 26, 2005
Creator:
unknown
Object Type:
Letter
System:
The UNT Digital Library
569 Form Letters from concerned citizens supporting Niagara Falls Air Force Reserve and Guard Base
Community Correspondence - 569 Form Letters from concerned citizens supporting Niagara Falls Air Force Reserve and Guard Base
Date:
July 26, 2005
Creator:
unknown
Object Type:
Letter
System:
The UNT Digital Library
576 Form Letters from concerned citizens supporting Niagara Falls Air Force Reserve and Guard Base
Community Correspondence - 576 Form Letters from concerned citizens supporting Niagara Falls Air Force Reserve and Guard Base
Date:
July 26, 2005
Creator:
unknown
Object Type:
Letter
System:
The UNT Digital Library
670 letters from concerned citizens supporting Niagrara Falls Air Force Reserve Base
Community Correspondence - 670 letters from concerned citizens supporting Niagrara Falls Air Force Reserve Base
Date:
July 26, 2005
Creator:
unknown
Object Type:
Letter
System:
The UNT Digital Library
682 Form Letters from concerned citizens supporting Niagara Falls Air Force Reserve and Guard Base
Community Correspondence - 682 Form Letters from concerned citizens supporting Niagara Falls Air Force Reserve and Guard Base
Date:
July 26, 2005
Creator:
unknown
Object Type:
Letter
System:
The UNT Digital Library
S. 852: The Fairness in Asbestos Injury Resolution Act of 2005
From Summary: "This report provides an overview of S. 852, the Fairness in Asbestos Injury Resolution (FAIR) Act of 2005. The bill would largely remove asbestos claims from the courts in favor of the administrative process set out in the bill. The bill would establish the Office of Asbestos Disease Compensation to award damages to asbestos claimants on a no-fault basis from the Asbestos Injury Claims Resolution Fund."
Date:
April 26, 2005
Creator:
Brooks, Nathan
Object Type:
Report
System:
The UNT Digital Library
15th Street News (Midwest City, Okla.), Vol. 30, No. 13, Ed. 1 Friday, January 26, 2001
Newspaper from Rose State College in Midwest City, Oklahoma that includes national, local, and campus news along with advertising.
Date:
January 26, 2001
Creator:
Baldwin, Alisha
Object Type:
Newspaper
System:
The Gateway to Oklahoma History