The majority of U.S. commercial floor space is cooled by rooftop HVAC units (RTUs). RTU popularity derives chiefly from their low initial cost and relative ease of service access without disturbing building occupants. Unfortunately, current RTUs are inherently inefficient due to a combination of characteristics that unnecessarily increase cooling loads and energy use. 36% percent of annual U.S. energy, and two-thirds of electricity, is consumed in and by buildings. Commercial buildings consume approximately 4.2 quads of energy each year at a cost of $230 billion per year, with HVAC equipment consuming 1.2 quads of electricity. More than half of all U.S. commercial floor space is cooled by packaged HVAC units, most of which are rooftop units (RTUs). Inefficient RTUs create an estimated 3.5% of U.S. CO{sub 2} emissions, thus contributing significantly to global warming5. Also, RTUs often fail to maintain adequate ventilation air and air filtration, reducing indoor air quality. This is the second HyPak project to be supported by DOE through NETL. The prior project, referred to as HyPak-1 in this report, had two rounds of prototype fabrication and testing as well as computer modeling and market research. The HyPak-1 prototypes demonstrated the high performance capabilities of the HyPak …

This contract proposal is in response to the Federal Columbia River Power System Biological Opinion Implementation Plan/Update Proposed Action (UPA) associated with increasing the number of Snake River sockeye smolts by 150,000. To accomplish this proposal the cooperation and efforts of three government entities has been planned (e.g., Idaho Department of Fish and Game (IDFG), Oregon Department of Fish and Wildlife (ODFW), and the National Marine Fisheries Service (NMFS)). Improvements at the IDFG Eagle Fish Hatchery and NMFS Burley Creek Hatchery will focus on increasing sockeye salmon captive broodstock and egg production. Improvements at the ODFW Oxbow Fish Hatchery will be made to accommodate the incubation, hatching and rearing of 150,000 sockeye salmon smolts for release into Idaho's Sawtooth Valley, Upper Salmon River near IDFG's Sawtooth Fish Hatchery and/or Redfish Lake Creek 1.4 km downstream of Redfish Lake. Modifications to Oxbow Fish Hatchery (ODFW) will include retro-fit existing pond drains so pond cleaning effluent water can be routed to the pollution abatement pond, and modifications to the abatement pond. Also included in this project as an added phase, was the rerouting of the hatchery building effluent water to meet state DEQ guidelines for the use of formalin to treat salmonid …

The Santa Clara County Planar Solid Oxide Fuel Cell (PSOFC) project demonstrated the technical viability of pre-commercial PSOFC technology at the County 911 Communications headquarters, as well as the input fuel flexibility of the PSOFC. PSOFC operation was demonstrated on natural gas and denatured ethanol. The Santa Clara County Planar Solid Oxide Fuel Cell (PSOFC) project goals were to acquire, site, and demonstrate the technical viability of a pre-commercial PSOFC technology at the County 911 Communications headquarters. Additional goals included educating local permit approval authorities, and other governmental entities about PSOFC technology, existing fuel cell standards and specific code requirements. The project demonstrated the Bloom Energy (BE) PSOFC technology in grid parallel mode, delivering a minimum 15 kW over 8760 operational hours. The PSOFC system demonstrated greater than 81% electricity availability and 41% electrical efficiency (LHV net AC), providing reliable, stable power to a critical, sensitive 911 communications system that serves geographical boundaries of the entire Santa Clara County. The project also demonstrated input fuel flexibility. BE developed and demonstrated the capability to run its prototype PSOFC system on ethanol. BE designed the hardware necessary to deliver ethanol into its existing PSOFC system. Operational parameters were determined for running the …

Polyamines regulate important cellular functions and polyamine dysregulation frequently occurs in cancer. The objective of this study was to use a systems approach to study the relative effects of PG-11047, a polyamine analogue, across breast cancer cells derived from different patients and to identify genetic markers associated with differential cytotoxicity. A panel of 48 breast cell lines that mirror many transcriptional and genomic features present in primary human breast tumours were used to study the antiproliferative activity of PG-11047. Sensitive cell lines were further examined for cell cycle distribution and apoptotic response. Cell line responses, quantified by the GI50 (dose required for 50% relative growth inhibition) were correlated with the omic profiles of the cell lines to identify markers that predict response and cellular functions associated with drug sensitivity. The concentrations of PG-11047 needed to inhibit growth of members of the panel of breast cell lines varied over a wide range, with basal-like cell lines being inhibited at lower concentrations than the luminal cell lines. Sensitive cell lines showed a significant decrease in S phase fraction at doses that produced little apoptosis. Correlation of the GI50 values with the omic profiles of the cell lines identified genomic, transcriptional and proteomic …

As a gateway for scientific discovery, the Argonne Leadership Computing Facility (ALCF) works hand in hand with the world's best computational scientists to advance research in a diverse span of scientific domains, ranging from chemistry, applied mathematics, and materials science to engineering physics and life sciences. Sponsored by the U.S. Department of Energy's (DOE) Office of Science, researchers are using the IBM Blue Gene/L supercomputer at the ALCF to study and explore key scientific problems that underlie important challenges facing our society. For instance, a research team at the University of California-San Diego/ SDSC is studying the molecular basis of Parkinson's disease. The researchers plan to use the knowledge they gain to discover new drugs to treat the disease and to identify risk factors for other diseases that are equally prevalent. Likewise, scientists from Pratt & Whitney are using the Blue Gene to understand the complex processes within aircraft engines. Expanding our understanding of jet engine combustors is the secret to improved fuel efficiency and reduced emissions. Lessons learned from the scientific simulations of jet engine combustors have already led Pratt & Whitney to newer designs with unprecedented reductions in emissions, noise, and cost of ownership. ALCF staff members provide …

We calculate the single transverse-spin asymmetry for open charm production in pp collisions within the QCD collinear factorization approach. We include contributions from both twist-three quark-gluon and tri-gluon correlation functions. We find that the quark-gluon correlation functions alone generate only a very small asymmetry for open charm production in the kinematic region of current interest at RHIC, so that the observation of any significant single-spin asymmetry would be a clear indication of the presence of tri-gluon correlations inside a polarized proton. We furthermore demonstrate that the tri-gluon contribution could be very different for the production of D and \bar{D} mesons. These features make the single spin asymmetry in open charm production in polarized pp collisions at RHIC an excellent probe of tri-gluon correlation functions.

This report discusses the current political state of Afghanistan, as well as the Afghan government. This report also discusses Afghanistan's relationship with the United States, particularly U.S. efforts to urge President Hamid Karzai to address corruption within the Afghan government.

This report highlights design and component selection considerations for compressed gas hydrogen fueling stations operating at 5000 psig or 350 bar. The primary focus is on options for compression and storage – in terms of practical equipment options as well as various system configurations and how they influence delivery performance and station economics.

This report includes background information on Bolivia's political unrest, particularly regarding instability in shifting leaderships, economic situation, and relations with the United States.

This report consists of the budget reconciliation process with timing of legislative action.

This report describes substantive enforcement procedures associated withthe budget resolution explains the concept of a "deeming resolution" discusses House and Senate action on deeming resolutions, and provides information on a related topic, waiving a bar against the consideration of budgetary legislation for a fiscal year before a budget resolution for that fiscal year was adopted.

This report examines the procedures of the Emergency Economic Stabilization Act of 2008 (Division A of H.R. 1424, P.L. 110-343) and explains how they differ from the regular parliamentary mechanisms of the House and Senate. It will be updated as needed.

The Emergency Economic Stabilization Act of 2008 (Division A of H.R. 1424, P.L. 110-343) empowers the Secretary of the Treasury to purchase certain "troubled assets" as a means to stabilize the economy. This report examines this procedure and explains how it differs from the regular parliamentary mechanisms of the House and Senate.

A letter report issued by the Government Accountability Office with an abstract that begins "Established in 1934 to enforce the securities laws and protect investors, the Securities and Exchange Commission (SEC) plays an important role in maintaining the integrity of the U.S. securities markets. Pursuant to the Accountability of Tax Dollars Act of 2002, SEC is required to prepare and submit to Congress and the Office of Management and Budget audited financial statements. GAO agreed, under its audit authority, to perform the audit of SEC's financial statements. GAO's audit determined whether, in all material respects, (1) SEC's fiscal year 2008 financial statements were reliable and (2) SEC's management maintained effective internal control over financial reporting and compliance with laws and regulations. GAO also tested SEC's compliance with selected laws and regulations."

Other written product issued by the Government Accountability Office with an abstract that begins "Presented is GAO's performance and accountability report for fiscal year 2008. In the spirit of the Government Performance and Results Act, this annual report informs the Congress and the American people about what we have achieved on their behalf. The financial information and the data measuring GAO's performance contained in this report are complete and reliable."

A letter report issued by the Government Accountability Office with an abstract that begins "The Federal Emergency Management Agency (FEMA), the Department of Homeland Security (DHS) agency that administers the National Flood Insurance Program (NFIP), estimates that subsidized properties--those that receive discounted premium rates that do not fully reflect the properties' actual flood risk--experience as much as five times the flood damage as properties that do not qualify for subsidized rates. Almost one in every four residential policies has subsidized rates that are on average 35-40 percent of the full-risk rate. Unprecedented losses from the 2005 hurricane season and NFIP's periodic need to borrow from the Department of the Treasury to pay flood insurance claims has raised concerns about the impact that subsidized premium rates have on the longterm financial solvency of NFIP. GAO designated NFIP as high-risk in March 2006; as of June 2008, NFIP's debt stood at $17.4 billion. This report (1) provides information on NFIP's inventory of subsidized properties and (2) examines NFIP's current approach to subsidized properties and the advantages and disadvantages of options for reducing the costs associated with these properties. To do this work, GAO analyzed data on policies and claims and collected available …

A letter report issued by the Government Accountability Office with an abstract that begins "Amid ongoing operations in Iraq and Afghanistan, the Army embarked in 2004 on a plan to create a modular, brigade-based force that would be equally capable as its divisional predecessor in part because it would have advanced equipment and specialized personnel. GAO has previously reported that restructuring and rebuilding the Army will require billions of dollars for equipment and take years to complete. For this report, GAO assessed the extent to which the Army has (1) developed a plan to link funding with results and (2) evaluated its modular force designs. GAO analyzed Army equipment and personnel data, key Army reports, planning documents, performance metrics, testing plans, and funding requests. GAO also visited Army Training and Doctrine Command, including selected Army proponents and schools; Army Reserve Command; and the National Guard Bureau."

This report describes recent developments in the assistance effort in post-authoritarian Iraq and key issues of potential interest to Congress.

This report identifies a number of issues related to establishing marine protected areas (MPAs) in the United States. It begins by defining the concept and administrative actions taken to provide spatial protection in marine areas. It then considers some of the key issues and potential benefits and costs of designating additional MPAs. It concludes by summarizing current congressional interest in the topic and legislation proposed during the 110th Congress.

This report covers the North American Free Trade Agreement (NAFTA) and U.S.-Mexico drug trafficking. It also looks at migration, environmental issues, legislation in the 110th Congress, and the relationship between the Bush Administration and Mexico.

In an extension of the Associated Particle Imaging technique that is used for the detection and imaging of hidden explosives, the present measurements use a beam of tagged 14.1 MeV neutrons in coincidence with two or more gammas to probe for the presence of fissionable materials. We have measured neutron-gamma-gamma coincidences with targets of depleted uranium, tungsten, lead, iron, and carbon and will present results that show the multiple-coincidence counting rate for the depleted uranium is substantially higher than any of the non-fissionable materials. In addition, the presence of coincidences involving delayed particle spectra provides a signature for fissionable materials that is distinct from that for non-fissionable ones. Information from the tagged neutron involved in the coincidence event is used to compute the position of the fissionable material in all three dimensions. The result is an imaging probe for fissionable materials that is compact and portable, and produces relatively low levels of background radiation. Simultaneous measurements on packages of interest for both explosives and fissionable materials are now feasible.

This report provides background information on DDG-1000 (Zumwalt) program. The issue for Congress for FY2009 was how to take the Navy's new position on destroyer procurement into account in marking up the Navy's proposed FY2009 budget.

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