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Analysis of HLA-DP association with beryllium disease susceptibility in pooled exposed populations
Berylliosis or Chronic Beryllium Disease is a chronic granulomatous disorder primarily involving the lung associated with the exposition to low doses of Beryllium (Be) in the workplace. Berylliosis risk has been associated with the presence of a glutamate at position 69 of the HLA-DP beta chain (HLA-DPbetaGlu69) that is expressed in about 97% of disease cases and in 27% of the unaffected Be-exposed controls (p<0.0001) (Richeldi et al. Science 1993; 262: 242-244.12). Since this first observation of an immunogenetic association between berylliosis and HLA-DPbetaGlu69 a number of studies have confirmed the role of this marker as the primary gene of susceptibility of berylliosis (Richeldi et al Am J Ind Med. 1997; 32:337-40; Wang et al J. Immunol. 1999; 163: 1647-53; Saltini et al Eur Respir J. 2001 18:677-84; Rossman et al Am J Respir Crit Care Med. 2002 165:788-94). Moreover, a structure/function interaction between HLA-DP molecules carrying Glu69 and beryllium in driving and developing the immune response against beryllium itself has been observed as: (1) Be-specific T-cells clones obtained from berylliosis patients recognize beryllium as antigen only when presented in the context of the HLA-DP{beta}Glu69 molecules but not in the context of HLA-DP allelic variants carrying Lys69 (Lombardi G et …
Date:
December 19, 2009
Creator:
Cesare Saltini, Massimo Amicosante
Object Type:
Report
System:
The UNT Digital Library
The Bastrop Advertiser (Bastrop, Tex.), Vol. 156, No. 84, Ed. 1 Saturday, December 19, 2009
Semi-weekly newspaper from Bastrop, Texas that includes local, state and national news along with advertising.
Date:
December 19, 2009
Creator:
Wright, Cyndi
Object Type:
Newspaper
System:
The Portal to Texas History
The Baytown Sun (Baytown, Tex.), Vol. 89, No. 324, Ed. 1 Saturday, December 19, 2009
Daily newspaper from Baytown, Texas that includes local, state, and national news along with advertising.
Date:
December 19, 2009
Creator:
Clements, Clifford E.
Object Type:
Newspaper
System:
The Portal to Texas History
Beam dynamics of the Neutralized Drift Compression Experiment-II (NDCX-II),a novel pulse-compressing ion accelerator
Intense beams of heavy ions are well suited for heating matter to regimes of emerging interest. A new facility, NDCX-II, will enable studies of warm dense matter at {approx}1 eV and near-solid density, and of heavy-ion inertial fusion target physics relevant to electric power production. For these applications the beam must deposit its energy rapidly, before the target can expand significantly. To form such pulses, ion beams are temporally compressed in neutralizing plasma; current amplification factors of {approx}50-100 are routinely obtained on the Neutralized Drift Compression Experiment (NDCX) at LBNL. In the NDCX-II physics design, an initial non-neutralized compression renders the pulse short enough that existing high-voltage pulsed power can be employed. This compression is first halted and then reversed by the beam's longitudinal space-charge field. Downstream induction cells provide acceleration and impose the head-to-tail velocity gradient that leads to the final neutralized compression onto the target. This paper describes the discrete-particle simulation models (1-D, 2-D, and 3-D) employed and the space-charge-dominated beam dynamics being realized.
Date:
December 19, 2009
Creator:
Friedman, A.; Barnard, J. J.; Cohen, R. H.; Grote, D. P.; Lund, S. M.; Sharp, W. M. et al.
Object Type:
Report
System:
The UNT Digital Library
Considering value of information when using CFD in design
This thesis presents an approach to find lower resolution CFD models that can accurately lead a designer to a correct decision at a lower computational cost. High-fidelity CFD models often contain too much information and come at a higher computational cost, limiting the designs a designer can test and how much optimization can be performed on the design. Lower model resolution is commonly used to reduce computational time. However there are no clear guidelines on how much model accuracy is required. Instead experience and intuition are used to select an appropriate lower resolution model. This thesis presents an alternative to this ad hoc method by considering the added value of the addition information provided by increasing accurate and more computationally expensive models.
Date:
December 19, 2009
Creator:
Misra, John Satprim
Object Type:
Thesis or Dissertation
System:
The UNT Digital Library
Evaluation of bisphenol E cyanate ester for the resin-injection repair of advanced composites
This thesis is a compilation of a general introduction and literature review that ties together the subsequent chapters which consist of two journal articles that have yet to be submitted for publication. The overall topic relates to the evaluation and application of a new class of cyanate ester resin with unique properties that lend it applicable to use as a resin for injection repair of high glass transition temperature polymer matrix composites. The first article (Chapter 2) details the evaluation and optimization of adhesive properties of this cyanate ester and alumina nanocomposites under different conditions. The second article (Chapter 3) describes the development and evaluation of an injection repair system for repairing delaminations in polymer matrix composites.
Date:
December 19, 2009
Creator:
Lio, Wilber Yaote
Object Type:
Thesis or Dissertation
System:
The UNT Digital Library
Perry Daily Journal (Perry, Okla.), Vol. 117, No. 247, Ed. 1 Saturday, December 19, 2009
Daily newspaper from Perry, Oklahoma that includes local, state, and national news along with advertising.
Date:
December 19, 2009
Creator:
Brown, Gloria
Object Type:
Newspaper
System:
The Gateway to Oklahoma History
Redox Activation of Alkene Ligands in Platinum Complexes with Non-innocent Ligands
Article discussing the redox activation of alkene ligands in platinum complexes with non-innocent ligands.
Date:
December 19, 2009
Creator:
Boyer, Julie L.; Cundari, Thomas R., 1964-; DeYonker, Nathan J.; Rauchfuss, Thomas B. & Wilson, Scott R.
Object Type:
Article
System:
The UNT Digital Library
SAVANNAH RIVER SITE TANK 18 AND TANK 19 WALL SAMPLER PERFORMANCE
A sampling tool was required to evaluate residual activity ({mu}Curies per square foot) on the inner wall surfaces of underground nuclear waste storage tanks. The tool was required to collect a small sample from the 3/8 inch thick tank walls. This paper documents the design, testing, and deployment of the remotely operated sampling device. The sampler provides material from a known surface area to estimate the overall surface contamination in the tank prior to closure. The sampler consisted of a sampler and mast assembly mast assembly, control system, and the sampler, or end effector, which is defined as the operating component of a robotic arm. The mast assembly consisted of a vertical 30 feet long, 3 inch by 3 inch, vertical steel mast and a cantilevered arm hinged at the bottom of the mast and lowered by cable to align the attached sampler to the wall. The sampler and mast assembly were raised and lowered through an opening in the tank tops, called a riser. The sampler is constructed of a mounting plate, a drill, springs to provide a drive force to the drill, a removable sampler head to collect the sample, a vacuum pump to draw the sample from …
Date:
December 19, 2009
Creator:
Leishear, R.; Thaxton, D.; Minichan, R.; France, T.; Steeper, T.; Corbett, J. et al.
Object Type:
Article
System:
The UNT Digital Library
Terrorist Attacks in Mumbai, India, and Implications for U.S. Interests
None
Date:
December 19, 2009
Creator:
unknown
Object Type:
Report
System:
The UNT Digital Library
X-ray resonant magnetic scattering investigations of hexagonal multiferroics RMnO3 (R = Dy, Ho, Er)
Electricity and magnetism were unified into a common subject by James Clerk Maxwell in the nineteenth century yielding the electromagnetic theory. Four equations govern the dynamics of electric charges and magnetic fields, commonly known as Maxwell's equations. Maxwell's equations demonstrate that an accelerated charged particle can produce magnetic fields and a time varying magnetic field can induce a voltage - thereby linking the two phenomena. However, in solids, electric and magnetic ordering are most often considered separately and usually with good reason: the electric charges of electrons and ions are responsible for the charge effects, whereas the electron spin governs magnetic properties.
Date:
December 19, 2009
Creator:
Nandi, Shibabrata
Object Type:
Thesis or Dissertation
System:
The UNT Digital Library
Advances in Bayesian Model Based Clustering Using Particle Learning
Recent work by Carvalho, Johannes, Lopes and Polson and Carvalho, Lopes, Polson and Taddy introduced a sequential Monte Carlo (SMC) alternative to traditional iterative Monte Carlo strategies (e.g. MCMC and EM) for Bayesian inference for a large class of dynamic models. The basis of SMC techniques involves representing the underlying inference problem as one of state space estimation, thus giving way to inference via particle filtering. The key insight of Carvalho et al was to construct the sequence of filtering distributions so as to make use of the posterior predictive distribution of the observable, a distribution usually only accessible in certain Bayesian settings. Access to this distribution allows a reversal of the usual propagate and resample steps characteristic of many SMC methods, thereby alleviating to a large extent many problems associated with particle degeneration. Furthermore, Carvalho et al point out that for many conjugate models the posterior distribution of the static variables can be parametrized in terms of [recursively defined] sufficient statistics of the previously observed data. For models where such sufficient statistics exist, particle learning as it is being called, is especially well suited for the analysis of streaming data do to the relative invariance of its algorithmic complexity …
Date:
November 19, 2009
Creator:
Merl, D M
Object Type:
Report
System:
The UNT Digital Library
The Albany News (Albany, Tex.), Vol. 134, No. 26, Ed. 1 Thursday, November 19, 2009
Weekly newspaper from Albany, Texas that includes local, county, and state news along with extensive advertising.
Date:
November 19, 2009
Creator:
Lucas, Melinda L.
Object Type:
Newspaper
System:
The Portal to Texas History
The Altus Times (Altus, Okla.), Vol. 111, No. 356, Ed. 1 Thursday, November 19, 2009
Daily newspaper from Altus, Oklahoma that includes local, state, and national news along with advertising.
Date:
November 19, 2009
Creator:
Bush, Michael
Object Type:
Newspaper
System:
The Gateway to Oklahoma History
Archer County News (Archer City, Tex.), No. 47, Ed. 1 Thursday, November 19, 2009
Weekly newspaper from Archer City, Texas that includes local, state, and national news along with advertising.
Date:
November 19, 2009
Creator:
Lewis, Shelley
Object Type:
Newspaper
System:
The Portal to Texas History
The Bastrop Advertiser (Bastrop, Tex.), Vol. 156, No. 75, Ed. 1 Thursday, November 19, 2009
Semi-weekly newspaper from Bastrop, Texas that includes local, state and national news along with advertising.
Date:
November 19, 2009
Creator:
Wright, Cyndi
Object Type:
Newspaper
System:
The Portal to Texas History
The Baytown Sun (Baytown, Tex.), Vol. 89, No. 302, Ed. 1 Thursday, November 19, 2009
Daily newspaper from Baytown, Texas that includes local, state, and national news along with advertising.
Date:
November 19, 2009
Creator:
Clements, Clifford E.
Object Type:
Newspaper
System:
The Portal to Texas History
Beam dynamics of the Neutralized Drift Compression Experiment-II (NDCX-II), a novel pulse-compressing ion accelerator
Intense beams of heavy ions are well suited for heating matter to regimes of emerging interest. A new facility, NDCX-II, will enable studies of warm dense matter at {approx}1 eV and near-solid density, and of heavy-ion inertial fusion target physics relevant to electric power production. For these applications the beam must deposit its energy rapidly, before the target can expand significantly. To form such pulses, ion beams are temporally compressed in neutralizing plasma; current amplification factors of {approx}50-100 are routinely obtained on the Neutralized Drift Compression Experiment (NDCX) at LBNL. In the NDCX-II physics design, an initial non-neutralized compression renders the pulse short enough that existing high-voltage pulsed power can be employed. This compression is first halted and then reversed by the beam's longitudinal space-charge field. Downstream induction cells provide acceleration and impose the head-to-tail velocity gradient that leads to the final neutralized compression onto the target. This paper describes the discrete-particle simulation models (1-D, 2-D, and 3-D) employed and the space-charge-dominated beam dynamics being realized.
Date:
November 19, 2009
Creator:
Friedman, A; Barnard, J J; Cohen, R H; Grote, D P; Lund, S M; Sharp, W M et al.
Object Type:
Article
System:
The UNT Digital Library
The Canadian Record (Canadian, Tex.), Vol. 119, No. 47, Ed. 1 Thursday, November 19, 2009
Weekly newspaper from Canadian, Texas that includes local, state and national news along with some advertising.
Date:
November 19, 2009
Creator:
Brown, Laurie Ezzell
Object Type:
Newspaper
System:
The Portal to Texas History
Capsule Performance Optimization in the National Ignition Campaign
None
Date:
November 19, 2009
Creator:
Landen, O L; Boehly, T R; Bradley, D K; Braun, D G; Callahan, D A; Celliers, P M et al.
Object Type:
Article
System:
The UNT Digital Library
The Colony Courier-Leader (The Colony, Tex.), Vol. 28, No. 42, Ed. 1 Thursday, November 19, 2009
Weekly newspaper from The Colony, Texas that includes local, state, and national news along with advertising.
Date:
November 19, 2009
Creator:
Mann, Rick
Object Type:
Newspaper
System:
The Portal to Texas History
Comparison of Rights in Military Commission Trials and Trials in Federal Criminal Court
This report provides a brief summary of legal issues raised by the choice of forum for trying accused terrorists and a table comparing selected military commissions rules under the Military Commissions Act, as amended, to the corresponding rules that apply in federal court.
Date:
November 19, 2009
Creator:
Elsea, Jennifer K.
Object Type:
Report
System:
The UNT Digital Library
Cooper Review (Cooper, Tex.), Vol. 129, No. 45, Ed. 1 Thursday, November 19, 2009
Weekly newspaper from Cooper, Texas that includes local, state, and national news along with advertising.
Date:
November 19, 2009
Creator:
Palmer, Roger
Object Type:
Newspaper
System:
The Portal to Texas History
Corporate Crime: Prosecutors Adhered to Guidance in Selecting Monitors for Deferred Prosecution and Non-Prosecution Agreements, but DOJ Could Better Communicate Its Role in Resolving Conflicts
Testimony issued by the Government Accountability Office with an abstract that begins "Recent cases of corporate fraud and mismanagement heighten the Department of Justice's (DOJ) need to appropriately punish and deter corporate crime. Recently, DOJ has made more use of deferred prosecution and non-prosecution agreements (DPAs and NPAs), in which prosecutors may require company reform, among other things, in exchange for deferring prosecution, and may also require companies to hire an independent monitor to oversee compliance. This testimony addresses (1) the extent to which prosecutors adhered to DOJ's monitor selection guidelines, (2) the prior work experience of monitors and companies' opinions of this experience, and (3) the extent to which companies raised concerns about their monitors, and whether DOJ had defined its role in resolving these concerns. Among other steps, GAO reviewed DOJ guidance and examined the 152 agreements negotiated from 1993 (when the first 2 were signed) through September 2009. GAO also interviewed DOJ officials, obtained information on the prior work experience of monitors who had been selected, and interviewed representatives from 13 companies with agreements that required monitors. These results, while not generalizable, provide insights into monitor selection and oversight."
Date:
November 19, 2009
Creator:
United States. Government Accountability Office.
Object Type:
Text
System:
The UNT Digital Library