In order to perform the various experiments with a bubble chamber, a high intensity flash tube is used. This report briefly describes the power supplies designed and constructed to power these lamps.

The power supplies designed and constructed to power high intensity flash tubes used in bubble chamber experiments are briefly described and are accompanied by a schematic diagram of the layout. (D.C.W.)

These procedures are intended to be used for the initial operation of the expansion system and serve as a basis for a more complete and revised form to be written once operating experience has been gained. An attempt has been made to offer a logical and systematic presentation to facilitate operation and maintenance of the system by the operating personnel. Thus, the sequence of valve actuations has been presented in matrix and check list form to minimize errors; this also has the advantage of making it easier to adapt certain expansion system procedures to programmed control by a process control computer.

Prior to assembly into the 80" bubble chamber, the expansion system was subjected to a series of tests to check piston dynamics and gain information on the reliability of the various components. Furthermore, the rest provided operating personnel with the opportunity to become familiar with the operation and maintenance of the expansion system. Two separate tests were performed with the apparatus that was located at the north end of the AGS experimental area; one during the week of Oct. 15 and the other during the week of Nov. 12. The system was run with helium gas supplied from AGS compressor room and the piston was operated at room temperature.

One of the major, as well as first, decisions which must be taken on a large chamber is to decide on the direction of the magnetic field, i.e., vertical or horizontal. Either alternative has advantages and disadvantages ad it is the intention of this note to discuss these features.

The aim of this series of experiments was to evaluate the existence of abscopal effects of irradiation. No attempt was made towards the elucidation of mechanisms. Very early in the history of radiological research it was noticed radiation produces both local and general effects involving the entire body. Gauss and Lembcke introduced the term "Roentgenkater" (radiation sickness). They ascribed these "General Effects" to the circulation of toxic substances released from cells that disintegrated following irradiation.

Human iron metabolism has been extensively studied in the past twenty-five years with the radioisotopes iron⁵⁵ and iron⁵⁹. Before the availability of the whole body counter, however, iron absorption studies were performed by the indirect methods of fecal assay of unabsorbed radioiron, and estimation of red cell incorporation of absorbed tracer. The few long-term excretion studies performed required numerous assumptions, since human iron excretion was less well understood. Whole body counting provides a simple and accurate method of measuring the total body retention of administrative tracer iron⁵⁹, thus making absorption and subsequent excretion determinations possible with a single radioiron study. The energetic gamma emissions of iron⁵⁹ permit ready external detection with small quantities of isotope, Normal radioiron distribution is uniform throughout the circulating red cell mass and thus minimize geometry influences on the counting efficiency, 0nly the 45.1 day half-life of iron⁵⁹ limits long term iron turnover studies. Measurements of iron⁵⁹ absorption and long-term body turnover have been under way at Brookhaven National Laboratory for over two years. The present paper outlines some of the results of these studies, and discusses some implications of the method.

The magnetic field of the AGS ring can contain particles of magnetic rigidity about 34 Bv/c. This includes not only protons of kinetic energy 33 Bev, but also 32 Bev deuterons, 64 Bev alpha particles, and conceivably heavier nuclei such as 188 Bev carbon nuclei. It will be shown in this paper that such nuclei can be injected and accelerated in the AGS if some rather small modifications are made in the injection and acceleration systems. What physics could be done with such beams? Several types of experiments may be suggested. In the first place, since the deuteron is a rather loosely bound combination of a neutron and a proton, it is likely to break up when it hits a target nucleus (stripping reaction). In a considerable fraction of the collisions the neutron will go straight on with essentially unchanged energy (half the deuteron energy). Therefore, with an internal target bombarded by 30 Bev deuterons one should obtain an intense, rather well collimated and monochromatic beam of 15 Bev neutrons in the forward direction.

Maintenance of polarization of polarized protons in a linear accelerator is known to be feasible. Circular accelerators present a different problem, and the investigation of the interaction of orbit dynamics and particle polarization in general is undertaken. The equation of motion of the spin vector of a charged particle in a magnetic field as formulated by Bargmann, Michel, and Telegdi is utilized in the study of depolarization for several accelerators. High values of depolarization are obtained, and means for avoiding such depolarization are suggested. (D.C.W.)

This technical report describes the toxicity observations on mice of varying borate-glucose molar ratios and relative potencies (p) (4) for the pentaborate and tetraborate drug. This report outlines the methods and results of this experiment and provides a discussion of the results.

The rapid advances in many technologically important areas have not only served to accentuate the increased demands for high temperature metals and ceramics but have necessitated a more through knowledge of their physical properties when exposed to high temperature service. Toward this latter end, the use of X-ray diffraction has proved an invaluable tool in providing data of regions of thermal stability, expansion coefficients, solid solubility limits, and phase transformations by direct examination at temperature. Since this Laboratory has for some time now been engaged in the study of refractory nuclear materials, it was thought desirable to employ and possibly extend this technique to temperatures ranging up to 3000°C. This communication will describe the equipment developed for this purpose, with experimental results to be described in subsequent publications.

Since the discovery of the Straub and Feuer as well as Laki et al. that ATP bound to G-actin is transformed to ADP and inorganic phosphate during polymerization of actin (1, 2), it has become increasingly clear that the chemical changes in the nucleotide are related to the change in the physical state of the protein. Barany, Biro, Molnar and Straub have shown that highly purified actin preparation free of any enzyme which would use ATP, ADP or AMP as a substrate still catalyze the breakdown of ATP (3) thus supporting the original idea that the ATP to ADP transformation is related to the globular to fibrous transformation of the actin protein itself. Mommaerts was the first to show that the ADP formed during polymerization remains bound to F-actin and Ulbrecht et al. while extending Mommaert's finding on exhaustively purified actin preparations have shown that the P1 formed during polymerization is not bound to F-actin. The stoichiometry of the splitting and the tightness of binding of the ADP lead inevitably to questions in regard to the position of bond breaking during the hydrolysis and to the nature of the forces involved in the tight binding of ADP to F-actin. To …

The potassium-argon age of the Sikhote Alin iron meteorite has been determined. The value is 1.7 + 0.2 x 10⁹ years. Previous lead data suggest an age of 4.6 x 10⁹ years . The date of solidification may be the sum of these two ages.

The scope of the AGS complex has expanded rapidly during the three years since an accelerated beam was first obtained. Demand for research time far exceeds the amount available although facilities have been much increased. At the same time, experiments are being designed which are more complicated than previous ones and which make more stringent demands on the accelerator and on its auxiliary equipment. There is a continuous trend of experiments to particle beams of greater momentum, as the experimental techniques are refined. This use of increased momentum means that larger areas are required for the apparatus and that more power is necessary for the magnetic optics. All beam-sharing at the AGS is done by multiple use of each accelerated pulse because our experience indicates that pulse-by-pulse beam-sharing is relatively inefficient. (Expansion chambers have seldom been used at the AGS.) The problems of scheduling experiments becomes increasingly complex since combinations must be found satisfying the criteria: maximum number of experiments to run simultaneously; minimum downtime to be taken for rearrangement between successive experimental arrays

The angle by which a magnet deflects the trajectory of a particle in the x-z plane is proportional to the integral [integral not transcribed] taken over the trajectory wherever B≠0. Alternating gradient focusing is achieved by designing magnets so that I=I(x) varies linearly with x over a suitable x interval. Usually this is done by shaping the poles to give a linear variation of By with x while keeping the length of the magnet constant for different x. Certain advantaged may be gained by varying the effective length of the magnet with x and keeping By constant so that the integral varies properly with x. Figure 1 shows several such poles for which the trajectory length, and hence the integral (1), varies approximately from 2/3 to 4/3 of the mean value.

The relation between trace kinetic parameters of cell populations and the statistics used in studies on cell populations is discussed. It is pointed out that responses in cell populations are complex and subject to many perturbations. Some of these are discussed. It is concluded that a complete check list of sources of error is required for studies of great accuracy, and a calculus to help in combining heterogeneous data is needed for studies of systems of great complexity.

This technical report discusses techniques that have been developed for "computing the angular thermal flux spectrum emerging from a lattice. These methods are applied to water lattices and it is found that the computed spectra are sensitive to the geometrical description of the lattice, but insensitive to the anisotropic scattering by water. Comparisons with measured spectra indicate that corrections for gradients and the finite size of the experimental lattice are important." -- from abstract (p. 3).

Technical report describes how glasses and crystals subjected to ionizing radiation develop absorption bands and become colored. The coloring of defects can be used to determine how nuclear reactor induced defects anneal out or disappear as an irradiated sample is heated.

The role of the marrow as a site for antibody formation has been considered for many years. In 1912 Ludke reported the appearance of antibody in cultures of marrow cells obtained from previously immunized rabbits. Specific agglutinins for killed typhoid bacilli and lysins for ox red cells and sheep red cells were detected in the culture media 2 to 5 days later. However, the cultured cells failed to produce antibody when these antigens were added to the media. Similar findings by Reiter, Przygode, and Schilf appeared in the early literature with regard to the appearance of antibodies to various antigens in tissue cultures of bone marrow from immunized animals, along with failure to elicit antibody formation by addition of antigen to the culture resulted from the addition of excess amounts of antigen, so that if antibody synthesis occurred, the excess antigen combined with antibody and significant amounts of free antibody could not be detected in the culture media. Thorbecke and Keuning observed an increase in antibody in culture fluids when bone marrow fragments from rabbits immunized to paratyphoid B vaccine were cultured in roller tubes.

A study is being made of two-prong antiproton interactions in hydrogen at 3.25 Bev/c. About 2250 two-prong events were measured on automatic digitized machines and their reconstruction and analysis were performed with standard programs. Of the total number of events 1003 were classified as elastic interactions. About 500 inelastic events were examined using bubble density estimates in addition to criteria based on distribution values in the classification procedure. The inelastic events in which a secondary nucleon or antinucleon was unambiguously identified were used to obtain limits for annihilation and non-annihilation partial cross sections. The two-prong events were 57% of the total. Results for angular distributions and cross sections are presented in graphs and tables. (M.C.G.)

In the reprocessing of spent solid fuels from nuclear reactors by direct volatilization, one of the major problems is the removal of heat from the highly exothermic gas-solid reactions. The use of fluidized beds of inert granular material as heat transfer media to control these exothermic reactions forms the basis of one approach to volatile reprocessing which is under development at BNL The engineering scale work carried out under this development program is discussed.

The Brookhaven Bubble Chamber Group is developing a Hough-Powell fast analysis system (HPD)1 for bubble chamber photographs. High precision measurements are made with a computer controlled flying spot digitizer. We are currently testing the track selection programs for the system. We have just completed a study of a method for automatic bubble density measurements.

Mammalian bone marrow contains a considerable number of small lymphoid cells (small lymphocytes and small lymphocyte-like cells). The total number of these cells (50,000 to 500,000 per mm3) depends on species, age and other factors. The origin, function and fate of these cells remain obscure in many respects. In particular, it has not been shown beyond doubt, if and to what extent small lymphoid cells enter the bone marrow via the blood stream or if their origin is in part or entirely within the bone marrow. In addition it has not been clearly shown whether or not these cells may function as multipotential hemopoietic stem cells. Results obtained from experiments with irradiated parabiotic animals and animals given regional fractioned doses of X-irradiation, and transplantation of leukocytes from peripheral blood into lethally irradiated recipients afford indirect evidence that peripheral blood of mice and rats may contain stem cells capable of DNA synthesis and division.

Technique used in deriving values of the linac ball tuner settings to produce various fields is discussed briefly, and tables showing ball tuner change numbers and values used in making up the ball tuner change numbers are given.