The purpose of this investigation is to make more detailed studies of transformations. Fourteen compounds have been examined by high temperature X-ray diffraction for this purpose. The investigations have been carried out in such a way as to reveal: 1. the existence of transformations, 2. the influence of polarizability on thermal expansion, 3. the anisotropy of expansion, and 4. the discontinuity of thermal expansion.

Copper(II) and oxovanadium(IV) ions resemble one another magnetically in having one unpaired electron in their complexes irrespective of their geometrical structures and bond types involved. Copper(II) complexes with antiferromagnetic exchange are well known. On the contrary, antiferromagnetic exchange in oxovanadium(IV) complexes is rather new and not well established. Very few oxovanadium(IV) complexes have been reported to have this anomalous magnetic property. In the investigation of the magnetic properties of oxovanadium(IV) complexes, we have successfully prepared two series of new oxovanadium(IV) complexes with N-salicylideneamino acids.

This study is concerned with the nature of the relatively unusual bonding which occurs in organolithium compounds as a direct result of the oligomerization and possible explanations for that bonding.

At the time this work was begun, there was some confusion about the technique necessary for the successful synthesis of organomagnesium compounds in hydrocarbon solvents and without solvents. It was decided to repeat the work of Bryce-Smith and Zakharkin. Thus began the study of the synthesis of organomagnesium compounds without solvents; the study of the reaction products of these organomagnesium compounds in hydrocarbons plus 2-butanone compared to the reaction products of the corresponding etheral Grignard reagent plus 2-butanone; and a preliminary study of the nature of these organomagnesium compounds in hydrocarbon solvents.

The study herein described involved the detection of pyridine N-oxide reductase activity in cell-free extracts of E. coli 9723, the determination of co-factors necessary for the enzymatic process, a study of the optimum conditions for enzyme catalysis, and a general characterization of the enzyme.

This study reported herein involves the synthesis and determination of certain biological activities of 4,5-dihydroxy-2-pyridinealanine and the synthesis of 3-pyridine-N-methylalanine.

The study reported herein concerns itself with the isolation of melaninless mutants of S. antibioticus, ATCC, 3723, and with the demonstration that at least one of the sites of mutation involves that of the enzyme, tyrosinase.

In many series of compounds, intensity of biological activity and chemical reactivity are proportional. Generally whenever a alkyl group replaces a reactive hydrogen atom, as would be the case for an N-substituted hydroxylamine as compared to hydroxylamine, the over-all biological activity of the resulting compound is lower than that of its nonalkylated analogue. Since toxicity and physiological activity are not proportional, this comparison can only suggest possible types of derivatives to prepare and test.

This thesis describes experiments made to test the corrosion inhibition of quaternary amines on steel.

This thesis will explore and study rhodium, a group VIII element that has rarely been studied.

The procedure of Takimoto, Denault, and Hotta was followed in order to prepare 4-amino-3-hydrazino-5-methyl-s-triazole hydrochloride (II) and its precursor, triamino-guanidine hydrochloride (I).

The primary objective of this work was to prepare dichloroketene.

Since Djerassi and Scholz found that 2-(aryloxy-methyl)imidazolines and their hydrochloride salts exhibit vasoconstrictive properties, the 1,2-(I) 1,3-(II) and 1,4-bis-(2-imidazolinylmethoxy) benzene (III) analogs (Fig. 1, p.2) were chosen for synthesis in order to test them for their effective vasoconstrictive characteristics and for whatever other physiological properties they might exhibit.

In this work, the principal concern will be with the coupling reaction and it is anticipated that the other reactions referred to above will be considered further when products of the RX-R'Li reactions are discussed.

This thesis contains the exploration and investigation of self-diffusion of Na-22 in Molten PbCl2-NaCl mixtures.

This thesis is concerned with the thermal decomposition of a series of alkyllithium compounds in the pure state in an attempt to determine the relative stability of alkyllithium compounds and to examine the mechanism of the elimination reaction.

The specific goal of the investigation was the measurement, as a function of temperature, of the self-diffusion coefficients of Pb210 and Cl36 in PbCl2-KCl compositions in the region of the first compound, and to calculate from these data the activation energy necessary for the diffusion of these ions.

This thesis investigates the synthesis, characterization, and optical isomerism of some cobalt (III) complex compounds.

The pyrolysis of sec-butyllithium in solution was studied in an attempt to understand the loss of stereo-specificity and the atypical kinetics that have been reported. Additionally, the effect of added lithium alkoxides was studied to determine their effects on the highly reactive sec-butyllithium substrate.

The objective of this investigation was to determine the electronic effects of the halogen atoms in dihaloketenes such as dichloroketene and dibromoketene.

An investigation of the cycloaddition behavior of dichloroketene with various types of olefins seemed in order to determine if dichloroketene behaved similarly to dialkylketenes. It was anticipated that a study of this type would indicate the reactivity of dichloroketene to various types of olefinic compounds and thus establish if the ease of cycloaddition with dichloroketene parallels the nucleophilicity of the olefin as it does in dialkylketenes.

This work is an extension of Yin's work studying the diffusion of Na ion in the PbCl2-NaCl system, but at more dilute compositions of NaCl.

Since only one example of an asymmetric synthesis which involved an intermediate containing an optically active ligand has been reported, two questions immediately arise: "Is this type of asymmetric synthesis an isolated example, or is it a stepping stone toward a generalized trend for Co (III) which may be extended to include levo rotatory, as well as dextro rotatory molecules?" In addition, asymmetric synthesis affords a new avenue for synthesizing resolved neutral complexes.

The object of this thesis is to establish the diffusion coefficient of Na ion in PbCl2-NaCl mixtures and to compare its relationship to the other species.