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CancerNet: a unified deep learning network for pan‑cancer diagnostics (open access)

CancerNet: a unified deep learning network for pan‑cancer diagnostics

Article states that despite remarkable advances in cancer research, cancer remains one of the leading causes of death worldwide. The author's proposed framework for cancer diagnostics detects cancers and their tissues of origin using a unified model of cancers encompassing 33 cancers represented in The Cancer Genome Atlas. Their model exploits the learned features of different cancers reflected in the respective dysregulated epigenomes, holding a great promise in early cancer detection.
Date: June 13, 2022
Creator: Gore, Steven & Azad, Rajeev K.
Object Type: Article
System: The UNT Digital Library
Caputo Fractional Derivative and Quantum-Like Coherence (open access)

Caputo Fractional Derivative and Quantum-Like Coherence

This article studies two forms of anomalous diffusions and discusses the joint use of these prescriptions, with a phenomenological method and a theoretical projection method, leading to two apparently different diffusion equations. The authors prove that the two diffusion equations are equivalent and design a time series that corresponds to the anomalous diffusion equation proposed.
Date: February 9, 2021
Creator: Culbreth, Garland; Bologna, Mauro; West, Bruce J. & Grigolini, Paolo
Object Type: Article
System: The UNT Digital Library
Cardiac and metabolic physiology of early larval zebrafish (Danio rerio) reflects parental swimming stamina (open access)

Cardiac and metabolic physiology of early larval zebrafish (Danio rerio) reflects parental swimming stamina

This article explores swimming stamina in fish. Mature adult zebrafish (Danio rerio) were subjected to a swimming performance test and then bred within performance groups to discover if enhanced swimming stamina in offspring appears only in juveniles/adults, or if these traits appear as early as larvae.
Date: February 24, 2012
Creator: Burggren, Warren W. & Gore, Matthew
Object Type: Article
System: The UNT Digital Library
Cardiorespiratory physiological phenotypic plasticity in developing air-breathing anabantid fishes (Betta splendens and Trichopodus trichopterus) (open access)

Cardiorespiratory physiological phenotypic plasticity in developing air-breathing anabantid fishes (Betta splendens and Trichopodus trichopterus)

This article discusses development plasticity of cardiorespiratory physiology in two air-breathing anabantid fishes.
Date: June 16, 2017
Creator: Mendez-Sanchez, Jose F. & Burggren, Warren W.
Object Type: Article
System: The UNT Digital Library
Cascading effects of COVID-19 on population mobility and air quality: An exploration including place characteristics using geovisualization (open access)

Cascading effects of COVID-19 on population mobility and air quality: An exploration including place characteristics using geovisualization

Article examining the population mobility and air quality before and after the lockdown (mandated restriction of activity) during the public health response to COVID-19. This article is part of the Special Issue on COVID-19.
Date: January 22, 2022
Creator: Atkinson, Samuel F.; Kala, Abhishek K. & Tiwari, Chetan
Object Type: Article
System: The UNT Digital Library
Case report: Early-onset osteoporosis in a patient carrying a novel heterozygous variant of the WNT1 gene (open access)

Case report: Early-onset osteoporosis in a patient carrying a novel heterozygous variant of the WNT1 gene

Article presents a case study of a 35 year-old Caucasian woman who experienced multiple vertebral fractures two months after her second pregnancy. The results suggest a potential role of heterozygous WNT1 variants in the pathogenesis of early-onset osteoporosis. The authors suggest that teriparatide is one of the most appropriate available therapies for such cases.
Date: August 8, 2022
Creator: Campopiano, Maria Cristina; Fogli, Antonella; Michelucci, Angela; Mazoni, Laura; Longo, Antonella; Borsari, Simona et al.
Object Type: Article
System: The UNT Digital Library
Cavity surface residues of PAD4 and SAG101 contribute to EDS1 dimer signaling specificity in plant immunity (open access)

Cavity surface residues of PAD4 and SAG101 contribute to EDS1 dimer signaling specificity in plant immunity

Article investigating whether the EPDs of PAD4 and SAG101 contribute to EDS1 dimer functions.
Date: October 27, 2021
Creator: Dongus, Joram A.; Bhandari, Deepak D.; Penner, Eva; Lapin, Dmitry; Stolze, Sara C.; Harzen, Anne et al.
Object Type: Article
System: The UNT Digital Library
Celebrating 20 Years of Genetic Discoveries in Legume Nodulation and Symbiotic Nitrogen Fixation (open access)

Celebrating 20 Years of Genetic Discoveries in Legume Nodulation and Symbiotic Nitrogen Fixation

This article is a review cataloging and contextualizing all of the plant genes currently known to be required for SNF in two model legume species, Medicago truncatula and Lotus japonicus, and two crop species, Glycine max (soybean) and Phaseolus vulgaris (common bean). The authors also briefly consider the future of SNF genetics in the era of pan-genomics and genome editing.
Date: October 24, 2019
Creator: Roy, Sonali; Liu, Wei; Nandety, Raja Sekhar; Crook, Ashley; Mysore, Kirankumar S.; Pislariu, Catalina I. et al.
Object Type: Article
System: The UNT Digital Library
Cellular Plasticity in Response to Suppression of Storage Proteins in the Brassica napus Embryo (open access)

Cellular Plasticity in Response to Suppression of Storage Proteins in the Brassica napus Embryo

Article testing the tradeoff between protein and oil storage in oilseed crops by analyzing the effect of suppressing key genes encoding protein storage products (napin and cruciferin). This study provides mechanistic insights into the intriguing link between lipid and protein storage, which have implications for biotechnological strategies directed at improving oilseed crops.
Date: April 30, 2020
Creator: Rolletschek, Hardy; Schwender, Jorg; König, Christina; Chapman, Kent Dean; Romsdahl, Trevor; Lorenz, Christin et al.
Object Type: Article
System: The UNT Digital Library

Chandra and Magellan/FIRE follow-up observations of PSO167–13: An X-ray weak QSO at z = 6.515

This article presents the results of follow-up observations of the z = 6.515 radio-quiet QSO PSO167–13, which is interacting with a close companion galaxy with the goal to confirm the existence of the X-ray source and to investigate the rest-frame UV properties of the QSO. The authors observed the PSO167–13 system with Chandra/ACIS-S (177 ks) and obtained new spectroscopic observations (7.2 h) with Magellan/FIRE.
Date: May 27, 2021
Creator: Vito, F.; Brandt, William Nielsen; Ricci, F.; Congui, E.; Connor, T.; Bañados, E. et al.
Object Type: Article
System: The UNT Digital Library
Characterization of the Nit6803 nitrilase homolog from the cyanotroph Pseudomonas fluorescens NCIMB 11764 (open access)

Characterization of the Nit6803 nitrilase homolog from the cyanotroph Pseudomonas fluorescens NCIMB 11764

This article reports the purification and characterization of a nitrilase (E.C. 3.5.5.1) (Nit11764) essential for the assimilation of cyanide as the sole nitrogen source by the cyanotroph, Pseudomonas fluorescens NCIMB 11764.
Date: January 16, 2021
Creator: Jones, Lauren B.; Wang, Xiaoqiang; Gullapalli, Jaya S. & Kunz, Daniel A.
Object Type: Article
System: The UNT Digital Library
Characterization of UGT716A1 as a Multi-substrate UDP:Flavonoid Glucosyltransferase Gene in Ginkgo biloba (open access)

Characterization of UGT716A1 as a Multi-substrate UDP:Flavonoid Glucosyltransferase Gene in Ginkgo biloba

This article discusses the generation of a transcriptomic dataset of G. biloba leaf tissue by high-throughput RNA sequencing to better understand flavonoid glucosylation in G. biloba.
Date: December 7, 2017
Creator: Su, Xiaojia; Shen, Guoan; Di, Shaokang; Dixon, R. A. & Pang, Yongzhen
Object Type: Article
System: The UNT Digital Library
Charge stabilization via electron exchange: excited charge separation in symmetric, central triphenylamine derived, dimethylaminophenyl–tetracyanobutadiene donor–acceptor conjugates (open access)

Charge stabilization via electron exchange: excited charge separation in symmetric, central triphenylamine derived, dimethylaminophenyl–tetracyanobutadiene donor–acceptor conjugates

This article hypothesizes and demonstrates a new mechanism to stabilize the charge separated states via the process of electron exchange among the different acceptor entities in multimodular donor–acceptor conjugates. This work constitutes the first example of stabilizing charge-separated states via the process of electron exchange.
Date: November 13, 2020
Creator: Yadav, Indresh S.; Alsaleh, Ajyal Z.; Misra, Rajneesh & D'Souza, Francis
Object Type: Article
System: The UNT Digital Library
Charged Particle Reflection by a Planar Artificially Structured Boundary With Electrostatic Plugging (open access)

Charged Particle Reflection by a Planar Artificially Structured Boundary With Electrostatic Plugging

This article uses a classical trajectory Monte Carlo simulation to investigate an artificially structured boundary for confinement and control of charged particles.
Date: November 30, 2017
Creator: Hedlof, R. M. & Ordonez, Carlos A.
Object Type: Article
System: The UNT Digital Library
Chemical and Genetic Studies on the Formation of Pyrrolones During the Biosynthesis of Cytochalasans (open access)

Chemical and Genetic Studies on the Formation of Pyrrolones During the Biosynthesis of Cytochalasans

This article investigates the role of the highly conserved α,β-hydrolase enzymes PyiE and ORFZ during the biosynthesis of pyrichalasin H and the ACE1 metabolite, respectively, using gene knockout and complementation techniques. Taken together the results suggest that the α,β-hydrolase enzymes are essential for first ring cyclisation, but the precise nature of the intermediates remains to be determined.
Date: November 4, 2020
Creator: Zhang, Haili; Hantke, Verena; Bruhnke, Pia; Skellam, Elizabeth & Cox, Russell J.
Object Type: Article
System: The UNT Digital Library
The chemical coupling between moist CO oxidation and gas-phase potassium sulfation (open access)

The chemical coupling between moist CO oxidation and gas-phase potassium sulfation

Article discusses how the chemical coupling between moist CO oxidation and transformation of gaseous potassium salts (KCl or KOH) in the presence and absence of SO2 was investigated experimentally and through chemical kinetic modeling. Analysis of the calculations indicates that sulfation pathways in the model involving KOSO3 contribute to the overprediction, but both the thermodynamic properties and rate constants in the model involve significant uncertainties and more work is required to resolve the discrepancy.
Date: December 15, 2022
Creator: Chanpirak, Arphaphon; Hashemi, Hamid; Frandsen, Flemming; Wu, Hao; Glarborg, Peter & Marshall, Paul
Object Type: Article
System: The UNT Digital Library
Childhood Asthma and Smoking: Moderating Effect of Preterm Status and Birth Weight (open access)

Childhood Asthma and Smoking: Moderating Effect of Preterm Status and Birth Weight

Article exploring the association between second-hand smoke exposure, asthma, and asthma severity in children ages 6-17 as well as the effect of birth weight and prematurity (BWP) on parental smoking and asthma. Results indicate that focused asthma interventions in children should inquire about BWP status as well as parental smoking and household smoke exposure to reduce asthma morbidity and mortality.
Date: April 17, 2021
Creator: Ogbu, Chukwuemeka E.; Ogbu, Stella C.; Khadka, Dibya & Kirby, Russell S.
Object Type: Article
System: The UNT Digital Library
The cisd gene family regulates physiological germline apoptosis through ced-13 and the canonical cell death pathway in Caenorhabditis elegans (open access)

The cisd gene family regulates physiological germline apoptosis through ced-13 and the canonical cell death pathway in Caenorhabditis elegans

This article examines how the disruption of the cisd-1 gene function, using RNA interference (RNAi), or mutant alleles [cisd-1(tm4993) deletion mutant, cisd-1(pnIs27) insertion mutant] led to germline abnormalities including an increase in the number of cell corpses and distal tip cell migration defects.
Date: April 17, 2018
Creator: King, Skylar D.; Gray, Chipo F.; Song, Luhua; Nechushtai, Rachel; Gumienny, Tina L; Mittler, Ron et al.
Object Type: Article
System: The UNT Digital Library
Classical trajectory Monte Carlo simulation of plasma fueling using magnetic plasma expulsion (open access)

Classical trajectory Monte Carlo simulation of plasma fueling using magnetic plasma expulsion

Article describes a study exploring the possibility of fueling a magnetically confined plasma using particle sources located inside of the plasma.
Date: July 11, 2019
Creator: Martinez, Armando & Ordonez, Carlos A.
Object Type: Article
System: The UNT Digital Library
Climate Metrics for C1–C4 Hydrofluorocarbons (HFCs) (open access)

Climate Metrics for C1–C4 Hydrofluorocarbons (HFCs)

This article looks at hydrofluorocarbons (HFCs) which are potent greenhouse gases that are potential substitutes for ozone depleting substances. The Kigali amendment lists 17 HFCs that are currently in commercial use to be regulated under the Montreal Protocol. Future commercial applications may explore the use of other HFCs, most of which currently lack an evaluation of their climate metrics. In this work, atmospheric lifetimes, radiative efficiencies (REs), global warming potentials (GWPs), and global temperature change potentials (GTPs) for all saturated HFCs with fewer than 5 carbon atoms are estimated to help guide future usage and policy decisions.
Date: May 11, 2020
Creator: Burkholder, James B. (James Bart), 1954-; Marshall, Paul; Bera, Partha P.; Francisco, Joseph S. & Lee, Timothy J.
Object Type: Article
System: The UNT Digital Library
Closed-form expressions for the magnetic fields of rectangular and circular finite-length solenoids and current loops (open access)

Closed-form expressions for the magnetic fields of rectangular and circular finite-length solenoids and current loops

This article discusses closed-form expressions for the magnetic fields produced by rectangular- and circular-shaped finite-length solenoids and current loops. The closed-form expression for the magnetic field of a rectangular-shaped finite-length solenoid is derived using the Biot–Savart law. Closed-form expressions for the magnetic fields of solenoids and current loops can be used to avoid approximations in analytical models and may reduce computation time in computer simulations.
Date: June 15, 2020
Creator: Hampton, S.; Lane, R. A.; Hedlof, R. M.; Phillips, R. E. & Ordonez, Carlos A.
Object Type: Article
System: The UNT Digital Library
Cluster embedding of ionic systems: Point charges and extended ions (open access)

Cluster embedding of ionic systems: Point charges and extended ions

This article presents a detailed analysis of the orbital energies of a representative cluster model of a high spin metal oxide, FeO, that has been made to determine the importance of different embedding schemes to represent the extended oxide crystal. The embedding of cluster models of oxides with point charges and with extensions of the embedding which take into account the spatial extent of the cations is examined with an emphasis on the consequences of this embedding for the relative ionization and excitation energies that are measured in core-level spectroscopies.
Date: May 1, 2019
Creator: Bagus, Paul S.; Sassi, Michael J. & Rosso, Kevin M.
Object Type: Article
System: The UNT Digital Library
The Cluster Transfer Function of AtNEET Supports the Ferredoxin–Thioredoxin Network of Plant Cells (open access)

The Cluster Transfer Function of AtNEET Supports the Ferredoxin–Thioredoxin Network of Plant Cells

This article develops an inducible expression system to study AtNEET function in mature plants using a time-course proteomics approach. The authors report that the suppression of AtNEET cluster transfer function results in drastic changes in the expression of different members of the ferredoxin (Fd), Fd-thioredoxin (TRX) reductase (FTR), and TRX network of Arabidopsis, as well as in cytosolic cluster assembly proteins.
Date: August 6, 2022
Creator: Zandalinas, Sara I.; Song, Luhua; Nechushtai, Rachel; Mendoza-Cózatl, David & Mittler, Ron
Object Type: Article
System: The UNT Digital Library
Code Comparison in Galaxy-scale Simulations with Resolved Supernova Feedback: Lagrangian versus Eulerian Methods (open access)

Code Comparison in Galaxy-scale Simulations with Resolved Supernova Feedback: Lagrangian versus Eulerian Methods

Authors of the article present a suite of high-resolution simulations of an isolated dwarf galaxy using four different hydrodynamical codes: Gizmo, Arepo, Gadget, and Ramses. They find reasonable agreement on the time-averaged star formation rates as well as the joint density–temperature distributions between all codes.
Date: June 16, 2023
Creator: Hu, Chia-Yu; Smith, Matthew C.; Teyssier, Romain; Bryan, Greg L.; Verbeke, Robbert; Emerick, Andrew et al.
Object Type: Article
System: The UNT Digital Library